Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RGS9BP Gene

protein-coding   GIFtS: 46
GCID: GC19P033166

regulator of G protein signaling 9 binding protein

(Previous name: regulator of G protein signalling 9 binding protein )
 Explore 3 diseases affiliated with
RGS9BP via our new
 Human Malady Compendium 
Biological research products
for RGS9BP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Regulator Of G Protein Signaling 9 Binding Protein1 2     FLJ457441
R9AP1 2 3 5     Regulator Of G Protein Signalling 9 Binding Protein1
PERRS1 2 5     Regulator Of G-Protein Signaling 9-Binding Protein2
RGS91 2 5     RGS9 Anchor Protein2
RGS9-Anchoring Protein2 3     

External Ids:    HGNC: 303041   Entrez Gene: 3885312   Ensembl: ENSG000001863267   OMIM: 6078145   UniProtKB: Q6ZS823   

Export aliases for RGS9BP gene to outside databases

Previous GC identifers: GC19P037862 GC19P029669


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RGS9BP:
The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction.
Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer
segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the
regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble
interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression
(PERRS), also known as bradyopsia. (provided by RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: R9BP_HUMAN, Q6ZS82
Function: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery
phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the
targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of
RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time
scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RGS9BP gene promoter:
         Spz1   AML1a   Sp1   p300   HNF-4alpha2   HNF-4alpha1   AREB6   Pax-3   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRGS9BP promoter sequence
   Search SABiosciences Chromatin IP Primers for RGS9BP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGS9BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.11   Ensembl cytogenetic band:  19q13.11   HGNC cytogenetic band: 19q13.11

RGS9BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGS9BP gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P033166:  view genomic region     (about GC identifiers)

Start:
33,166,313 bp from pter      End:
33,169,206 bp from pter
Size:
2,894 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: R9BP_HUMAN, Q6ZS82 (See protein sequence)
Recommended Name: Regulator of G-protein signaling 9-binding protein  
Size: 235 amino acids; 25148 Da
Subunit: Specifically interacts with isoform RGS9-1 of RGS9. Component of the RGS9-1-Gbeta5 complex composed of RGS9-1,
Gbeta5 (GNB5) and RGS9BP (By similarity)
Subcellular location: Membrane; Single-pass type IV membrane protein (By similarity)
Secondary accessions: Q6ZVJ6

Explore the universe of human proteins at neXtProt for RGS9BP: NX_Q6ZS82

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6ZS82

  • RGS9BP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_997274.2  
    ENSEMBL proteins: 
     ENSP00000334134  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for RGS9BP 
    GenScript Custom Purified and Recombinant Proteins Services for RGS9BP
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RGS9BP

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    RGS9BP for ontologies           About GeneDecksing



    RGS9BP Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RGS9BP 
    GenScript Custom Superior Antibodies Services for RGS9BP
    Novus Biologicals RGS9BP Antibody
    Search for Antibodies for RGS9BP at Abcam  
    Uscn Antibodies for RGS9BP
    ThermoFisher Antibodies for RGS9BP

    Assay Products for RGS9BP: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RGS9BP
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for RGS9BP


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RGS9BP for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR026513 RGS9BP
     IPR026512 RGS7BP/RGS9BP

    Graphical View of Domain Structure for InterPro Entry Q6ZS82

    ProtoNet protein and cluster: Q6ZS82

    UniProtKB/Swiss-Prot: R9BP_HUMAN, Q6ZS82
    Similarity: Belongs to the RGS7BP/RGS9BP family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: R9BP_HUMAN, Q6ZS82
    Function: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery
    phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the
    targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of
    RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time
    scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By
    similarity)

    miRNA
    Products:
        
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RGS9BP
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate RGS9BP (see all 15):
    hsa-miR-3130-5p hsa-miR-3173-3p hsa-miR-320a hsa-miR-148b* hsa-miR-193a-3p hsa-miR-601 hsa-miR-320d hsa-miR-4290
    SwitchGear 3'UTR luciferase reporter plasmidRGS9BP 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGS9BP (see all 7)
    OriGene shRNA RFP: RGS9BP
    OriGene siRNA: RGS9BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RGS9BP

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RGS9BP

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: RGS9BP (NM_207391)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGS9BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS9BP 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RGS9BP
    Search LifeMap BioReagents cell lines for RGS9BP

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS9BP

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rgs9bp):
     vision/eye 

    RGS9BP for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Visual signal transduction- Rods
    Visual signal transduction- Rods1.00
    Visual signal transduction- Cones0.39


    2 BioSystems Pathways for RGS9BP 
        Visual signal transduction- Cones
    Visual signal transduction- Rods


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RGS9BP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for RGS9BP (ENSP000003341344) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNAT1ENSP000002324614STRING: ENSP00000232461
    GNAT2ENSP000002513374STRING: ENSP00000251337
    GNB5ENSP000002618374STRING: ENSP00000261837
    PDE6AENSP000002552664STRING: ENSP00000255266
    PDE6BENSP000004202954STRING: ENSP00000420295
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009968negative regulation of signal transduction IEA--
    GO:0050908detection of light stimulus involved in visual perception IEA--


    RGS9BP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RGS9BP
    Search CenterWatch for drugs/clinical trials and news about RGS9BP / R9BP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RGS9BP gene: 
    NM_207391.2  

    Unigene Cluster for RGS9BP:

    Regulator of G protein signaling 9 binding protein
    Hs.528491  [show with all ESTs]
    Unigene Representative Sequence: AK124499
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000334176(uc002ntp.1)

    miRNA
    Products:
         
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RGS9BP
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate RGS9BP (see all 15):
    hsa-miR-3130-5p hsa-miR-3173-3p hsa-miR-320a hsa-miR-148b* hsa-miR-193a-3p hsa-miR-601 hsa-miR-320d hsa-miR-4290
    SwitchGear 3'UTR luciferase reporter plasmidRGS9BP 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGS9BP (see all 7)
    OriGene shRNA RFP: RGS9BP
    OriGene siRNA: RGS9BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RGS9BP
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: RGS9BP (NM_207391)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGS9BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS9BP 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGS9BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RGS9BP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGS9BP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS9BP

    Additional cDNA sequence: 

    AF086461.1 AK124499.1 AK127646.1 

    1 DOTS entry:

    DT.97819355 

    15 AceView cDNA sequences:

    AK127646 AW302149 BM673230 BQ187216 CF145448 BX645932 BM710194 AF086461 
    CF145408 BX116028 BM671616 BM707056 AI375213 W81663 BM562937 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RGS9BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCTCCCACT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RGS9BP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RGS9BP

    SOURCE GeneReport for Unigene cluster: Hs.528491
        SABiosciences Custom PCR Arrays for RGS9BP
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGS9BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RGS9BP
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGS9BP
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS9BP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS9BP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for RGS9BP gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rgs9bp1 , 5 regulator of G-protein signalling 9 binding protein1, 5 82.27(n)1
    83.4(a)1
      7 (21.37 cM)5
    2439231  NM_145840.31  NP_665839.11 
     355789985 
    chicken
    (Gallus gallus)
    Aves RGS9BP1 regulator of G protein signaling 9 binding protein 66.24(n)
    60.85(a)
      395170  NM_204505.1  NP_989836.1 
    lizard
    (Anolis carolinensis)
    Reptilia RGS9BP6
    --
    63(a)
    1 ↔ 1
    GL343483.1(178106-178819)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5592321 regulator of G-protein signaling 9-binding protein-like 62.39(n)
    53.42(a)
      559232  XM_682552.5  XP_687644.2 


    ENSEMBL Gene Tree for RGS9BP (if available)
    TreeFam Gene Tree for RGS9BP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/26 NCBI SNPs in RGS9BP are shown (see all 26    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1129400811,2
    C,--29671694(+) AAGACG/ACGCTA 1 -- ut312Minor allele frequency- A:0.06CSA WA 120
    rs1140259651,2
    C,F,--29671874(+) AAAGGG/ACTCTC 1 -- ut311Minor allele frequency- A:0.03WA 118
    rs802472931,2
    C,F,--29672076(+) GTGCGT/CGCTGG 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs1138889391,2
    C,--29672583(+) GCCACC/TGCACC 1 -- ds50012Minor allele frequency- T:0.02NA 122
    rs1898503321,2
    --33168107(+) TGCAGA/GAGCTT 1 -- ut310--------
    rs1825615271,2
    --33168124(+) CTATTA/GATAGA 1 -- ut310--------
    rs1172865851,2
    F,--33168322(+) TGGTTG/AGTCTG 1 -- ut311Minor allele frequency- A:0.03EA 120
    rs766189591,2
    C,F,--33168383(+) TAATCT/GTTCAG 1 -- ut312Minor allele frequency- G:0.04WA EA 238
    rs1485033691,2
    C,--33168402(+) TTTAG-/GAGAGTG 1 -- ut310--------
    rs2592931,2
    C,--33168412(-) CTCTCA/GGGACA 1 -- ut31 ese312Minor allele frequency- G:0.23NA WA CSA EA 374

    HapMap Linkage Disequilibrium report for RGS9BP (33166313 - 33169206 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RGS9BP: --
    Human Gene Mutation Database (HGMD): RGS9BP

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGS9BP
    DNA2.0 Custom Variant and Variant Library Synthesis for RGS9BP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RGS9BP for disorders           About GeneDecksing

    OMIM gene information: 607814   
    OMIM disorders: 608415  
    UniProtKB/Swiss-Prot: R9BP_HUMAN, Q6ZS82
  • Defects in RGS9BP are a cause of prolonged electroretinal response suppression (PERRS) [MIM:608415]; also
  • known as bradyopsia. PERRS is characterized by difficulty adjusting to sudden changes in luminance levels mediated by
    cones

    3 diseases for RGS9BP:    About MalaCards
    bradyopsia    atherosclerosis    retinitis

    Human Genome Epidemiology (HuGE) Navigator: RGS9BP (1 document)

    Export disorders for RGS9BP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RGS9BP gene integrated from 9 sources:
    (articles sorted by number of sources associating them with RGS9BP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation. (PubMed id 14702087)1, 2 Nishiguchi K.M.... Dryja T.P. (2004)
    2. R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. (PubMed id 12119397)1, 3 Hu G. and Wensel T.G. (2002)
    3. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1, 3 Bonaldo M.F.... Soares M.B. (1996)
    4. Type 5 G protein beta subunit (Gbeta5) controls the i nteraction of regulator of G protein signaling 9 (RGS9) with membrane anchors. (PubMed id 21511947)1 Masuho I....Martemyanov K.A. (2011)
    5. Novel mutations and electrophysiologic findings in RG S9- and R9AP-associated retinal dysfunction (Bradyopsia). (PubMed id 19818506)1 Michaelides M....Webster A.R. (2010)
    6. Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975)1 McGeachie M....Ramoni M.F. (2009)
    7. The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levels. (PubMed id 18318613)1 Stockman A....Sharpe L.T. (2008)
    8. Bradyopsia in an Asian man. (PubMed id 17698770)1 Cheng J.Y....Vithana E.N. (2007)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. (PubMed id 12560335)1 Hu G....Wensel T.G. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 388531 HGNC: 30304 AceView: FLJ45744 Ensembl:ENSG00000186326 euGenes: HUgn388531
    ECgene: RGS9BP H-InvDB: RGS9BP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RGS9BP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RGS9BP gene:
    Search GeneIP for patents involving RGS9BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for RGS9BP  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGS9BP   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGS9BP  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for RGS9BP   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS9BP  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RGS9BP   OriGene Custom Protein Services for RGS9BP  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RGS9BP
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGS9BP
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGS9BP
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RGS9BP
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS9BP
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGS9BP
     GenScript Custom Purified and Recombinant Proteins Services for RGS9BP GenScript cDNA clones with any tag delivered in your preferred vector for RGS9BP
     GenScript Custom Assay Services for RGS9BP GenScript Custom Superior Antibodies Services for RGS9BP
     GenScript Custom overexpressing Cell Line Services for RGS9BP CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RGS9BP promoter
     Search Chromatin IP Primers for RGS9BP
     RT2 qPCR Primer Assay in human, mouse, rat RGS9BP
     Search GNC Networks for RGS9BP
     SABiosciences Custom PCR Arrays for RGS9BP
     Search Tocris compounds for RGS9BP
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RGS9BP antibodies
     Search for Antibodies for RGS9BP at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for RGS9BP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     RGS9BP Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for RGS9BP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS9BP
     SwitchGear 3'UTR luciferase reporter plasmids for RGS9BP
     SwitchGear Promoter luciferase reporter plasmids for RGS9BP
     ThermoFisher Antibodies for RGS9BP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS9BP
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RGS9BP gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4