Aliases for RGS9 Gene
External Ids for RGS9 Gene
Previous GeneCards Identifiers for RGS9 Gene
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
GeneCards Summary for RGS9 Gene
RGS9 (Regulator Of G-Protein Signaling 9) is a Protein Coding gene. Diseases associated with RGS9 include bradyopsia and retinitis pigmentosa. Among its related pathways are Signaling by GPCR and Transport to the Golgi and subsequent modification. GO annotations related to this gene include signal transducer activity and protein complex binding. An important paralog of this gene is RGS12.
UniProtKB/Swiss-Prot for RGS9 Gene
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).