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RGS22 Gene

protein-coding   GIFtS: 48
GCID: GC08M100973

Regulator Of G-Protein Signaling 22

(Previous name: regulator of G-protein signalling 22)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Regulator Of G-Protein Signaling 221 2
Regulator Of G-Protein Signalling 221
CT1452
PRTD-NY22

External Ids:    HGNC: 244991   Entrez Gene: 261662   Ensembl: ENSG000001325547   OMIM: 6156505   UniProtKB: Q8NE093   

Export aliases for RGS22 gene to outside databases

Previous GC identifers: GC08M101044 GC08M096176


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RGS22 Gene:
RGS22 (regulator of G-protein signaling 22) is a protein-coding gene. Diseases associated with RGS22 include azoospermia, and squamous cell carcinoma. GO annotations related to this gene include GTPase activator activity.

UniProtKB/Swiss-Prot: RGS22_HUMAN, Q8NE09
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby
driving them into their inactive GDP-bound form (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RGS22 gene promoter:
         TBP   Pbx1a   HNF-3beta   Tal-1beta   C/EBPalpha   MEF-2A   aMEF-2   ITF-2   En-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRGS22 promoter sequence
   Search Chromatin IP Primers for RGS22

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RGS22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.2   Ensembl cytogenetic band:  8q22.2   HGNC cytogenetic band: 8q22.2

RGS22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGS22 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M100973:  view genomic region     (about GC identifiers)

Start:
100,973,164 bp from pter      End:
101,143,496 bp from pter
Size:
170,333 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RGS22_HUMAN, Q8NE09 (See protein sequence)
Recommended Name: Regulator of G-protein signaling 22  
Size: 1264 amino acids; 147163 Da
Secondary accessions: Q569L2 Q86Y71 Q9UFN6
Alternative splicing: 2 isoforms:  Q8NE09-1   Q8NE09-2   (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for RGS22: NX_Q8NE09

Explore proteomics data for RGS22 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RGS22 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273621.1  NP_001273622.1  NP_056483.3  

    ENSEMBL proteins: 
     ENSP00000354109   ENSP00000429382   ENSP00000430378   ENSP00000428212   ENSP00000427754  
     ENSP00000427798   ENSP00000429198   ENSP00000430903   ENSP00000427930  

    RGS22 Human Recombinant Protein Products:

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    Novus Biologicals RGS22 Protein
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    Cloud-Clone Corp. Proteins for RGS22

    RGS22 Antibody Products:

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    Abcam antibodies for RGS22
    Cloud-Clone Corp. Antibodies for RGS22
    ThermoFisher Antibody for RGS22
    LSBio Antibodies in human, mouse, rat for RGS22

    RGS22 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RGS22
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RGS22
    Cloud-Clone Corp. CLIAs for RGS22


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RGS: Regulators of G-protein signaling

    2 InterPro protein domains:
     IPR016137 Regulat_G_prot_signal_superfam
     IPR000342 RGS_dom

    Graphical View of Domain Structure for InterPro Entry Q8NE09

    ProtoNet protein and cluster: Q8NE09

    UniProtKB/Swiss-Prot: RGS22_HUMAN, Q8NE09
    Similarity: Contains 2 RGS domains


    RGS22 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RGS22_HUMAN, Q8NE09
    Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby
    driving them into their inactive GDP-bound form (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity IBA--
         
    RGS22 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RGS22:
     Synthetic lethal with Ras  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RGS22
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RGS22
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RGS22

    miRNA
    Products:
        
    miRTarBase miRNAs that target RGS22:
    hsa-mir-335-5p (MIRT018202)

    Block miRNA regulation of human, mouse, rat RGS22 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate RGS22:
    hsa-miR-3613-3p hsa-miR-186 hsa-miR-34b hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidRGS22 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RGS22
    Predesigned siRNA for gene silencing in human, mouse, rat RGS22

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for RGS22

    Clone
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    OriGene clones in human, mouse for RGS22 (see all 7)
    OriGene ORF clones in mouse, rat for RGS22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RGS22 (NM_015668)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGS22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS22

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for RGS22
    Browse ESI BIO Cell Lines and PureStem Progenitors for RGS22 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS22


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol2
    nucleus2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IBA--
    GO:0005886plasma membrane IBA--

    RGS22 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RGS22
    Interactions:

        Search GeneGlobe Interaction Network for RGS22

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for RGS22 (Q8NE093 ENSP000003541094) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3GLB2Q9NR463I2D: score=1 
    GSK3BENSP000003248064STRING: ENSP00000324806
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0038032termination of G-protein coupled receptor signaling pathway IEA--
    GO:0043547positive regulation of GTPase activity IBA--

    RGS22 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RGS22



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RGS22 gene (3 alternative transcripts): 
    NM_001286692.1  NM_001286693.1  NM_015668.4  

    Unigene Cluster for RGS22:

    Regulator of G-protein signaling 22
    Hs.120021  [show with all ESTs]
    Unigene Representative Sequence: BC092411
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360863(uc011lgz.1 uc003yjb.1 uc003yjc.1 uc010mbo.1)
    ENST00000523287(uc003yja.1) ENST00000517769(uc022azf.1) ENST00000517843
    ENST00000523437 ENST00000517828 ENST00000519421 ENST00000519725 ENST00000520923(uc022azh.1)
    ENST00000518474 ENST00000524182 ENST00000520117 ENST00000519092 ENST00000519408
    ENST00000522064 ENST00000523600 ENST00000518719
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RGS22 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate RGS22:
    hsa-miR-3613-3p hsa-miR-186 hsa-miR-34b hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidRGS22 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RGS22
    Predesigned siRNA for gene silencing in human, mouse, rat RGS22
    Clone
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    OriGene clones in human, mouse for RGS22 (see all 7)
    OriGene ORF clones in mouse, rat for RGS22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RGS22 (NM_015668)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGS22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS22
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RGS22
    OriGene qSTAR qPCR primer pairs in human, mouse for RGS22
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RGS22
      QuantiTect SYBR Green Assays in human, mouse, rat RGS22
      QuantiFast Probe-based Assays in human, mouse, rat RGS22

    Additional mRNA sequence: 

    AK097399.1 AK292559.1 AK302475.1 AK309194.1 AL117544.1 AY009106.1 BC036665.1 BC047060.1 
    BC050053.1 BC092411.1 

    8 DOTS entries:

    DT.95312569  DT.409140  DT.95219709  DT.120636512  DT.95154354  DT.120636483  DT.120636502  DT.95236101 

    Selected AceView cDNA sequences (see all 50):

    AK097399 BC036665 AI911174 BX101099 AI827862 BM929758 AI127752 BI823859 
    AL043929 AW072366 AW169431 BE463845 AI202895 BC047060 BC050053 AI674775 
    AI377703 BG772468 AY009106 AI005136 CD358527 AL117544 NM_015668 BU680476 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RGS22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAGCTCCA
    RGS22 Expression
    About this image

    RGS22 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RGS22 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.120021
        Custom PCR Arrays for RGS22
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    QuantiFast Probe-based Assays in human, mouse, rat RGS22
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS22

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RGS22 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rgs221 , 5 regulator of G-protein signalling 221, 5 79.73(n)1
    76.1(a)1
      15 (14.46 cM)5
    6265961  NM_001195748.11  NP_001182677.11 
     360094795 
    chicken
    (Gallus gallus)
    Aves RGS221 regulator of G-protein signaling 22 64.93(n)
    56.4(a)
      101751119  XM_004939994.1  XP_004940051.1 
    lizard
    (Anolis carolinensis)
    Reptilia RGS226
    regulator of G-protein signaling 22
    52(a)
    1 ↔ 1
    GL343394.1(335190-426000)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rgs221 regulator of G-protein signaling 22 59.24(n)
    50.5(a)
      100492604  XM_002934418.2  XP_002934464.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018840831 regulator of G-protein signaling 22-like 49.95(n)
    39.07(a)
      101884083  XM_005169778.1  XP_005169835.1 


    ENSEMBL Gene Tree for RGS22 (if available)
    TreeFam Gene Tree for RGS22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RGS22 (see all 2821)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2009923611,2
    Cuntested1101075809(+) CCCTGC/G/TTCTCT 2 N S mis10--------
    rs358802761,2
    C--100972918(+) TCAAA-/TAA/
    AATAATAA
    TAATA
    3 -- ds5001 cds11NA 2
    rs562891881,2
    C--100972951(+) TAATA-/ATA   
      ATAATA
    TAGTT
    2 -- ds5001 cds11Minor allele frequency- ATAATAATA:0.00NA 2
    rs732733011,2
    C,F--100973144(+) CTTAAT/CGACTG 1 -- ds50015Minor allele frequency- C:0.12WA CSA NA EA 362
    rs786655491,2
    F--100973250(+) CAGAAC/TAGCTA 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs736998961,2
    C,F--100973298(+) TCTTTA/CTTTAT 1 -- ut313Minor allele frequency- C:0.15WA CSA 122
    rs1864578181,2
    --100973406(+) AGCAGA/GATCTG 1 -- ut310--------
    rs1913502031,2
    --100973465(+) ATCTAC/TAGAAA 1 -- int10--------
    rs1836627721,2
    --100973511(+) ACTTAC/TATAGA 1 -- int10--------
    rs70154201,2
    C,F--100973549(+) cacccC/Aaatct 1 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for RGS22 (100973164 - 101143496 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RGS22:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2466799CNV Deletion19546169
    esv1068346CNV Deletion17803354
    esv1205143CNV Deletion17803354
    nsv396616CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RGS22
    DNA2.0 Custom Variant and Variant Library Synthesis for RGS22

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615650    OMIM disorders: --

    2 diseases for RGS22:    About MalaCards
    azoospermia    squamous cell carcinoma


    RGS22 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RGS22
    Human Genome Epidemiology (HuGE) Navigator: RGS22 (2 documents)

    Export disorders for RGS22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RGS22 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RGS22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. (PubMed id 20627871)1, 4 Wang J....Wu X. (Carcinogenesis 2010)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. RGS22, a novel cancer/testis antigen, inhibits epithelial cell invasion and metastasis. (PubMed id 21533872)1 Hu Y....Sha J. (amp 2011)
    5. RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits. (PubMed id 18703424)1 Hu Y....Sha J. (Biol. Reprod. 2008)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26166 HGNC: 24499 AceView: DKFZP434I092 Ensembl:ENSG00000132554 euGenes: HUgn26166
    ECgene: RGS22 H-InvDB: RGS22

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RGS22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RGS22 gene:
    Search GeneIP for patents involving RGS22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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