Aliases for RGS16 Gene
External Ids for RGS16 Gene
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
GeneCards Summary for RGS16 Gene
RGS16 (Regulator Of G-Protein Signaling 16) is a Protein Coding gene. Diseases associated with RGS16 include chordoid glioma. Among its related pathways are Activation of cAMP-Dependent PKA and G-AlphaQ Signaling. GO annotations related to this gene include calmodulin binding and GTPase activator activity. An important paralog of this gene is RGS18.
UniProtKB/Swiss-Prot for RGS16 Gene
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade