RGS12 Gene
protein-coding GIFtS: 59
GCID: GC04P003253
|
|
regulator of G-protein signaling 12(Previous name: regulator of G-protein signalling 12 )
| |
Aliases
for RGS12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Regulator Of G-Protein Signaling 121 2 | | Regulator Of G-Protein Signalling 121 2 |
| External Ids: | HGNC: 99941 | Entrez Gene: 60022 | Ensembl: ENSG000001597887 | OMIM: 6025125 | UniProtKB: O149243 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n339810 | |
Export aliases for RGS12 gene to outside databasesPrevious GC identifers: GC04P003321 GC04P003349 GC04P003348 GC04P003352 GC04P003294
Summaries
for RGS12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RGS12:
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein mayfunction as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. Thisprotein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identifiedfor this gene. Other alternative splice variants have been described but their biological nature has not beendetermined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RGS12_HUMAN, O14924Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby drivingthem into their inactive GDP-bound form
Gene Wiki entry for RGS12
|
Genomic Views
for RGS12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006051.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RGS12 gene promoter:
Max1 ER-alpha AML1a p53 RelA Evi-1 AREB6 S8 Zic3 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for RGS12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGS12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p16.3 Ensembl cytogenetic band: 4p16.3 HGNC cytogenetic band: 4p16.3RGS12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P003253: view genomic region
(about GC identifiers)
Start:
|
3,294,755 bp from pter |
End:
|
3,441,640 bp from pter |
Size:
|
146,886 bases |
Orientation:
|
plus strand |
|
Proteins
for RGS12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RGS12_HUMAN, O14924 (See
protein sequence)Recommended Name: Regulator of G-protein signaling 12 Size: 1447 amino acids; 156357 Da
Subunit: Interacts with GNAI1, GNAI2 and GNAI3; the interactions are GDP-dependent (By similarity)
Subcellular location: Nucleus
2 PDB 3D structures from  and Proteopedia  for RGS12:2EBZ (3D)
2KV8 (3D)
Secondary accessions: B1AQ30 B1AQ31 B1AQ32 O14922 O14923 O43510 O75338Alternative splicing: 4 isoforms: O14924-1 O14924-2 O14924-3 O14924-4 Explore the universe of human proteins at neXtProt for RGS12: NX_O14924
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14924
RGS12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_002917.1 NP_937870.1 NP_937872.1
ENSEMBL proteins: ENSP00000423003 ENSP00000339381 ENSP00000424251 ENSP00000372238 ENSP00000342133 ENSP00000338509 ENSP00000440566 ENSP00000304459 ENSP00000438888
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
RGS12 for ontologies About GeneDecksing
RGS12 Antibody Products:
Assay Products for RGS12: |
Protein
Domains /
Families
for RGS12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RGS12 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry O14924ProtoNet protein and cluster: O14924 5 Blocks protein families: IPB000342 Regulator of G-protein signalling (RGS) protein signature IPB001478 PDZ/DHR/GLGF domain IPB003109 G-alpha GTPase activator IPB003116 Raf-like Ras-binding IPB006020 Phosphotyrosine interaction domain
UniProtKB/Swiss-Prot: RGS12_HUMAN, O14924Domain: The GoLoco domain is necessary for interaction with GNAI1, GNAI2 and GNAI3 (By similarity)Similarity: Contains 1 GoLoco domainSimilarity: Contains 1 PDZ (DHR) domainSimilarity: Contains 1 PID domainSimilarity: Contains 2 RBD (Ras-binding) domainsSimilarity: Contains 1 RGS domain |
Function
for RGS12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RGS12_HUMAN, O14924Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby drivingthem into their inactive GDP-bound form Genatlas biochemistry entry for RGS12:negative regulator of G protein signaling 12,functioning as GTPase-activating protein for G protein alpha i and qsubunits,with four alternatively spliced isoforms,highly expressed in brain,kidney,thymus,prostate,C elegans EGL-10and yeast SST2 homolog
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RGS12 (NM_002926) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGS12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS12 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RGS12 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RGS12:
Animal Models:
Mouse knock-out Rgs12tm1Lex for RGS12
1 MGI phenotypic allele  for Rgs12 (no phenotypes)
RGS12 for phenotypes About GeneDecksing
|
Pathways & Interactions
for RGS12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | G-AlphaQ Signaling | | | 2 | Activation of cAMP-Dependent PKA | |
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RGS12
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RGS12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/27 Interacting proteins for RGS12 (O149242, 3 ENSP000003393814) via UniProtKB, MINT, STRING, and/or I2D (see all 27)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway |
TAS | 9651375 | | GO:0038032 | termination of G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0043547 | positive regulation of GTPase activity |
TAS | 9651375 | | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway |
-- | -- |
RGS12 for ontologies About GeneDecksing
|
Drugs & Compounds
for RGS12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RGS12
Search CenterWatch for drugs/clinical trials and news about RGS12
|
Transcripts
for RGS12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RGS12 gene (7 alternative transcripts): NM_002926.3 NM_198227.1 NM_198229.2 NM_198230.1 NM_198430.1 NM_198432.1 NM_198587.1 Unigene Cluster for RGS12: Regulator of G-protein signaling 12 Hs.527061 [show with all ESTs]Unigene Representative Sequence: NM_00292618/29 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 29): ENST00000506631(uc010ics.1) ENST00000511275(uc003ggu.2) ENST00000344733(uc003ggw.3 uc003ggy.1)
ENST00000502947(uc003ggx.1) ENST00000514268(uc011bvr.1) ENST00000382788(uc011bvs.2)
ENST00000511805 ENST00000513784 ENST00000338806(uc003ggz.3) ENST00000506998(uc010ict.1)
ENST00000508158(uc010icu.1) ENST00000505570 ENST00000512990 ENST00000503041
ENST00000504194(uc003gha.3 uc010icv.3) ENST00000512266 ENST00000513991(uc003ghb.2)
ENST00000515521
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): RGS12 (NM_002926) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGS12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS12 |
Additional cDNA sequence: AF030109.1 AF030110.1 AF030111.1 AF035152.1 AF464735.1 AF464736.1 AF464737.1 AK123325.1 AK290805.1 AK293767.1 AK301510.1 AK303135.1 AK308734.1 AK310999.1 AY987042.1 BC012118.1 BC028154.1 BC106944.1 BC118594.1 22 DOTS entries: DT.100795518 DT.100795519 DT.92429869 DT.455298 DT.101983738 DT.40132607 DT.101983740 DT.116803 DT.95274682 DT.99974025 DT.100795513 DT.92429866 DT.100721399 DT.95312695 DT.92054661 DT.116804 DT.121269468 DT.121269477 DT.40225421 DT.95362660 DT.100801601 DT.91898055 24/278 AceView cDNA sequences (see all 278): CB529763 AI928372 BE302699 AI304638 AI700519 CB529269 NM_198432 BM353618 AF464737 AL043625 AA861363 AA610280 AI298195 AI697612 BX282653 BM932171 BE890033 AI492460 BX106958 AW449762 AI738938 D44704 CD676395 BP354686
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RGS12 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 20a | · | 20b | ^ | 21 |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for RGS12
|
Expression
for RGS12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RGS12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGCTCCCTG
About this image
See RGS12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RGS12
SOURCE GeneReport for Unigene cluster: Hs.527061
UniProtKB/Swiss-Prot: RGS12_HUMAN, O14924Tissue specificity: Isoform 3 is brain specific
SABiosciences Expression via Pathway-Focused PCR Array including RGS12:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGS12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RGS12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGS12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS12 |
Orthologs
for RGS12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RGS12 gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RGS121 |
regulator of G-protein signaling 12 |
69.78(n)
73.73(a) |
|
395619 XM_420820.3 XP_420820.3 |
lizard
(Anolis carolinensis) |
Reptilia |
RGS126 |
-- |
68(a) |
1 ↔ 1 |
GL343236.1(2118468-2192785) |
African clawed frog
(Xenopus laevis) |
Amphibia |
480597302 |
-- |
75.65(n) |
|
48059730 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.186942 |
Danio rerio RGS12TS-S mRNA, complete cds, alternatively more |
75.13(n) |
|
AY427669.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
loco6 |
locomotion defects |
14(a) |
1 → many |
3R(18445690-18465082) |
ENSEMBL Gene Tree for RGS12 (if available)
TreeFam Gene Tree for RGS12 (if available) |
Paralogs
for RGS12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RGS12 gene
- RGS142 RGS112 RGS102 RGS72 RGS62 RGS92
13 SIMAP similar genes for RGS12 using alignment to 10 protein entries: RGS12_HUMAN (see all proteins):DKFZp761K1617 RGS10 RGS4 RGS17 RGS3 RGS14
RGS5 RGS16 RGS19 RGS1 RGS13 RGS8
RGS21
RGS12 for paralogs About GeneDecksing
|
Genomic Variants
for RGS12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for RGS12
8 CNVs: 31153 30195 53656 80147 91881 51384 3477 10033
6 Indels: 42067 27636 80148 91882 68628 68627 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGS12 |
|
Disorders
/ Diseases
for RGS12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RGS12 for disorders About GeneDecksing
OMIM gene information: 602512
OMIM disorders: --
6  diseases for RGS12: About MalaCardsbone giant cell tumor giant cell tumor squamous cell carcinoma schizophrenia
carcinoma prostatitis
Human Genome Epidemiology (HuGE) Navigator: RGS12 (4 documents)
Export disorders for RGS12 gene to outside databases
|
Publications
for RGS12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RGS12 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with RGS12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. (PubMed id 9651375)1, 2, 3, 9 Snow B.E....Siderovski D.P. (1998)
- Novel alternative splicing and nuclear localization of human RGS12 gene products. (PubMed id 10869340)1, 2, 9 Chatterjee T.K. and Fisher R.A. (2000)
- Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
- Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel. (PubMed id 11130074)1, 9 Schiff M.L....Diverse-Pierluissi M. (2000)
- Exome sequencing supports a de novo mutational paradi gm for schizophrenia. (PubMed id 21822266)1 Xu B....Karayiorgou M. (2011)
- Genetic variations in regulator of G-protein signalin g genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. (PubMed id 20627871)1 Wang J....Wu X. (2010)
- Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
- Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- Identification of the ligands of protein interaction domains through a functional approach. (PubMed id 17124247)1 Caratu G.... Zambrano N. (2007)
|
External Searches for RGS12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RGS12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RGS12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RGS12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RGS12 gene:
Search GeneIP for patents involving RGS12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RGS12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RGS12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGS12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGS12 | | | OriGene Protein Over-expression Lysate for RGS12 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RGS12 | | OriGene 3'-UTR Clone for RGS12 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGS12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RGS12 | | OriGene Custom Protein Services for RGS12 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RGS12 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGS12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGS12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RGS12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGS12 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for RGS12 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | RGS12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS12 |
|  |  |  | | | | ThermoFisher Antibodies for RGS12 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGS12 |
|
|
|
|
GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356977-web1.xennexinc.com
index build: 100 solr: 1.4
|
