Aliases for RGS11 Gene
External Ids for RGS11 Gene
Previous GeneCards Identifiers for RGS11 Gene
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
GeneCards Summary for RGS11 Gene
RGS11 (Regulator Of G-Protein Signaling 11) is a Protein Coding gene. Diseases associated with RGS11 include hereditary night blindness. Among its related pathways are Signaling by GPCR and Activation of cAMP-Dependent PKA. GO annotations related to this gene include signal transducer activity and GTPase activator activity. An important paralog of this gene is RGS12.
UniProtKB/Swiss-Prot for RGS11 Gene
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form