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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RGS11 Gene

protein-coding GIFtS: 61
GCID: GC16M000318

regulator of G-protein signaling 11

(Previous name: regulator of G-protein signalling 11 )

Explore 9 diseases affiliated with
RGS11 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Regulator Of G-Protein Signaling 11¹ ²
Regulator Of G-Protein Signalling 11¹ ²
RS11² ⁵

External Ids:	HGNC: 9993¹	Entrez Gene: 8786²	Ensembl: ENSG00000076344⁷	OMIM: 603895⁵	UniProtKB: O94810³

Export aliases for RGS11 gene to outside databases

Previous GC identifers: GC16M000337 GC16M000259 GC16M000260 GC16M000261

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RGS11:

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS

family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This

protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving

them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants

encoding distinct isoforms have been identified. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RGS11_HUMAN, O94810

Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving

them into their inactive GDP-bound form

Gene Wiki entry for RGS11

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RGS11 gene promoter:
Lmo2 AP-2gamma Evi-1 COMP1 AP-2beta AP-2alpha NF-Y AP-2alphaA CBF(2)
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for RGS11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGS11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3

RGS11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGS11 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M000318: view genomic region (about GC identifiers)

Start:	318,300 bp from pter	End:	325,980 bp from pter
Size:	7,681 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RGS11_HUMAN, O94810 (See protein sequence)

Recommended Name: Regulator of G-protein signaling 11

Size: 467 amino acids; 52946 Da

Subunit: Heterodimer with Gbeta5. Interacts with RGS7BP, leading to regulate the subcellular location of the

heterodimer formed with Gbeta5 (By similarity)

Secondary accessions: O75883 Q4TT71

Alternative splicing: 2 isoforms: O94810-1 O94810-2

Explore the universe of human proteins at neXtProt for RGS11: NX_O94810

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O94810

RGS11 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_003825.1 NP_899180.1

ENSEMBL proteins:

ENSP00000380876 ENSP00000168869 ENSP00000319069 ENSP00000352778 ENSP00000380874

ENSP00000411215

Human Recombinant Protein Products:

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	Uscn Proteins for RGS11

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005737	cytoplasm	IBA	--
GO:0005834	heterotrimeric G-protein complex	IEA	--
GO:0005886	plasma membrane	IBA	--
GO:0043234	protein complex	IDA	18468998

RGS11 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for RGS11

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RGS11 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR024066 Regulat_G_prot_signal_dom1

IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom

IPR000342 Regulat_G_prot_signal

IPR016137 Regulat_G_prot_signal_superfam

IPR000591 DEP_dom

Graphical View of Domain Structure for InterPro Entry O94810

ProtoNet protein and cluster: O94810

3 Blocks protein families:

IPB000342 Regulator of G-protein signalling (RGS) protein signature

IPB000591 Pleckstrin putative G-protein interacting domain

IPB001770 Gamma G-protein (transducin) signature

UniProtKB/Swiss-Prot: RGS11_HUMAN, O94810

Similarity: Contains 1 DEP domain

Similarity: Contains 1 G protein gamma domain

Similarity: Contains 1 RGS domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RGS11_HUMAN, O94810

Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving

them into their inactive GDP-bound form

Genatlas biochemistry entry for RGS11:

negative regulator of G protein signaling 11,predominantly expressed in both brain and retina,functioning as

GTPase-activating protein for G protein alpha subunits,G alpha i, G alpha o and complexing with G beta 5

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Gene Editing
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		Search LifeMap BioReagents cell lines for RGS11

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS11

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004871	signal transducer activity	IEA	--
GO:0005096	GTPase activator activity	IBA	--

RGS11 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for RGS11:

Increased S DNA content

Animal Models:
Mouse knock-out Rgs11^tm1Lex for RGS11
4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Rgs11):

mortality/aging

nervous system

reproductive system

vision/eye

RGS11 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

G-protein signaling_G-Protein alpha-i signaling cascades

G-protein signaling_G-Protein alpha-i signaling cascades

1.00

G-protein signaling G-Protein alpha-i signaling cascades

1.00

G-AlphaQ Signaling

G-AlphaQ Signaling

1.00

G-AlphaI Signaling

0.47

Calcium Regulation in the Cardiac Cell

Calcium Regulation in the Cardiac Cell

1.00

Myometrial Relaxation and Contraction Pathways

0.43

Activation of cAMP-Dependent PKA

cAMP Pathway

0.77

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for RGS11

G-protein signaling G-Protein alpha-i signaling cascades

3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RGS11

	cAMP Pathway
	G-AlphaI Signaling
	G-AlphaQ Signaling

1 GeneGo (Thomson Reuters) Pathway for RGS11

G-protein signaling G-Protein alpha-i signaling cascades

2 BioSystems Pathways for RGS11

	Myometrial Relaxation and Contraction Pathways
	Calcium Regulation in the Cardiac Cell

RGS11 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RGS11

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/34 Interacting proteins for RGS11 (O94810³ ENSP00000380876⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 34)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GNB5	O14775³, ENSP00000261837⁴	I2D: score=1 STRING: ENSP00000261837
GNA11	ENSP00000078429⁴	STRING: ENSP00000078429
GNA12	ENSP00000275364⁴	STRING: ENSP00000275364
GNA13	ENSP00000400717⁴	STRING: ENSP00000400717
GNA14	ENSP00000365807⁴	STRING: ENSP00000365807

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007186	G-protein coupled receptor signaling pathway	IEA	--
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	TAS	9789084
GO:0035556	intracellular signal transduction	IEA	--
GO:0038032	termination of G-protein coupled receptor signaling pathway	IEA	--
GO:0043547	positive regulation of GTPase activity	TAS	9789084

RGS11 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RGS11
Search CenterWatch for drugs/clinical trials and news about RGS11

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RGS11 gene (2 alternative transcripts):

NM_003834.1 NM_183337.1

Unigene Cluster for RGS11:

Regulator of G-protein signaling 11

Hs.65756 [show with all ESTs]

Unigene Representative Sequence: AB209582

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000397770(uc002cgj.1) ENST00000168869(uc002cgk.1) ENST00000316163(uc002cgi.1 uc010bqs.1)

ENST00000477143 ENST00000359740 ENST00000481672 ENST00000493449(uc010uue.2)

ENST00000472466 ENST00000397768 ENST00000431291

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGS11

Additional cDNA sequence:

AB016929.1 AB209582.1 AF035153.1 AF035154.1 AK091701.1 AK293564.1 AK294033.1 AK294448.1

AK308972.1 BC040504.1 BC141803.1 DQ656000.2 DQ656001.2 EF212269.1

8 DOTS entries:

DT.100020012 DT.307442 DT.99954033 DT.120711778 DT.120711872 DT.100740336 DT.120711834 DT.120711836

24/41 AceView cDNA sequences (see all 41):

BX955418 AB016929 NM_183337 AF035154 AL045210 AF035153 BE047585 BX507622

AL539076 BI770147 CA391209 NM_003834 CR593949 BF352690 BQ002302 AL138125

BC040504 BF352695 AX747138 BF338370 AK091701 CK299324 BM926869 BX089104

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for RGS11 About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10
SP1:																	-		-				-
SP2:					-		-						-
SP3:							-						-
SP4:
SP5:													-

ECgene alternative splicing isoforms for RGS11

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RGS11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGTCTCGG

About this image

RGS11 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Mature Horizontal Cells

Horizontal, Retina

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Brain

Neural Tube

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

See RGS11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RGS11

SOURCE GeneReport for Unigene cluster: Hs.65756

SABiosciences Custom PCR Arrays for RGS11

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGS11

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for RGS11 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RGS11¹	regulator of G-protein signaling 11	74.89(n) 70.96(a)		395621 XM_001231807.2 XP_001231808.2
lizard (Anolis carolinensis)	Reptilia	RGS11⁶	--	75(a)	1 ↔ 1	GL343507.1(540857-541523)
zebrafish (Danio rerio)	Actinopterygii	rgs11¹	regulator of G-protein signaling 11	64.91(n) 61.88(a)		559197 NM_001111161.1 NP_001104631.1
fruit fly (Drosophila melanogaster)	Insecta	CG7095³ CG42450¹	regulation of G-protein coupled receptor protein more³ CG42450¹	41(a)³ 52.38(n)¹ 42.18(a)¹		17E1³ 32874¹ NM_133100.2¹ NP_573328.2¹
worm (Caenorhabditis elegans)	Secernentea	eat-16⁶	EATing: abnormal pharyngeal pumping family member ...	30(a)	1 → many	I(9722541-9725602)

ENSEMBL Gene Tree for RGS11 (if available)
TreeFam Gene Tree for RGS11 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RGS11 gene

RGS14² RGS12² RGS10² RGS7² RGS6² RGS9²

14 SIMAP similar genes for RGS11 using alignment to 8 protein entries: RGS11_HUMAN (see all proteins):

RGS9 RGS17 RGS19 RGS20 RGS3 RGS10

RGS4 RGS13 RGS5 RGS7 RGS6 RGS18

RGS8 RGS16

RGS11 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs35527239^1,2	C	--	317878(+)	`CTACAC/TGACAC`	2	--	int¹		1		NA	2
rs4984857^1,2	C,F,A,H,	--	318050(+)	`ACGGGC/TGCTAC`	2	--	int¹		18		NS NA WA CSA EA	1872
rs183637558^1,2		--	318051(+)	`CGGGTA/GCTACA`	2	--	int¹		0	--	--	--	--
rs72765825^1,2	C,	--	318077(+)	`TATGCG/ATACAC`	2	--	int¹		6		NA CSA WA EA	362
rs142767416^1,2	C,	--	318154(+)	`TGCCT-/CACAGTA`	2	--	int¹		0	--	--	--	--
rs188442758^1,2		--	318191(+)	`TCACAA/CACGCT`	2	--	int¹		0	--	--	--	--
rs74003723^1,2	C,	--	318236(+)	`ACATGC/TCTCAT`	2	--	int¹		1		WA	2
rs3743876^1,2	C,F,	--	318243(+)	`TCATAC/TGCACA`	2	--	int¹		8		NA CSA WA EA	367
rs3743877^1,2	C,F,A,	--	318246(+)	`TACGCA/GCACAC`	2	--	int¹		1		EA	120
rs148164179^1,2		--	318275(+)	`TGCACC/TGTCAC`	2	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RGS11 (318300 - 325980 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RGS11
1 CNV: 5329

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGS11

DNA2.0 Custom Variant and Variant Library Synthesis for RGS11

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RGS11 for disorders           About GeneDecksing

OMIM gene information: 603895    OMIM disorders: --

9 diseases for RGS11:    About MalaCards

night blindness hereditary night blindness retinoschisis blindness

squamous cell carcinoma pharyngitis esophagitis adenocarcinoma

carcinoma

1 disease from the University of Copenhagen DISEASES database for RGS11:

Hereditary night blindness

Human Genome Epidemiology (HuGE) Navigator: RGS11 (2 documents)

Export disorders for RGS11 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for RGS11 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with RGS11)

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A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. (PubMed id 9789084)^{1, 2, 3} Snow B.E.... Siderovski D.P. (1998)
The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)^{1, 2} Martin J.... Pennacchio L.A. (2004)
Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)^{1, 2} Daniels R.J....Higgs D.R. (2001)
Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. (PubMed id 10339615)^{1, 2} Snow B.E.... Siderovski D.P. (1999)
Genetic variations in regulator of G-protein signalin g genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. (PubMed id 20627871)¹ Wang J....Wu X. (2010)
A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)¹ Liu C.Y....Christiani D.C. (2010)
RGS11 interacts preferentially with R7BP over Galpha( oa)--characterization of Gbeta5-free RGS11. (PubMed id 19497306)¹ Saleem Y. and Kim K.S. (2009)
Blood pressure is regulated by an alpha1D-adrenergic r eceptor/dystrophin signalosome. (PubMed id 18468998)¹ Lyssand J.S....Hague C. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8786	HGNC: 9993	AceView: RGS11	Ensembl:ENSG00000076344	euGenes: HUgn8786
ECgene: RGS11	H-InvDB: RGS11

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RGS11	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RGS11 gene
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Patent Information for RGS11 gene:
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regulator of G-protein signaling 11

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RGS11 Gene

regulator of G-protein signaling 11

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