RGR Gene
protein-coding GIFtS: 59
GCID: GC10P085994
|
|
retinal G protein coupled receptor
| |
Aliases
for RGR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Retinal G Protein Coupled Receptor1 2 | | RP441 2 5 | | RGR-Opsin1 | | RPE Retinal G-Protein Coupled Receptor2 | | RPE-Retinal G Protein-Coupled Receptor2 |
Export aliases for RGR gene to outside databasesPrevious GC identifers: GC10P084961 GC10P085226 GC10P086136 GC10P085669 GC10P079850 |
Summaries
for RGR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RGR:
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains aconserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze theconversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinalphotoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, theretinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomaldominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcriptvariants encoding different isoforms. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804Function: Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze theisomerization of the chromophore by a retinochrome-like mechanism
Gene Wiki entry for RGR (Retinal G protein coupled receptor)
|
Genomic Views
for RGR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RGR gene promoter:
GR GR-beta GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for RGR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q23 Ensembl cytogenetic band: 10q23.1 HGNC cytogenetic band: 10q23RGR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P085994: view genomic region
(about GC identifiers)
Start:
|
86,004,809 bp from pter |
End:
|
86,019,716 bp from pter |
Size:
|
14,908 bases |
Orientation:
|
plus strand |
|
Proteins
for RGR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804 (See
protein sequence)Recommended Name: RPE-retinal G protein-coupled receptor Size: 291 amino acids; 31874 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: A6NKK7 Q96FC5Alternative splicing: 3 isoforms: P47804-1 P47804-2 P47804-3 Explore the universe of human proteins at neXtProt for RGR: NX_P47804
Post-translational modifications:
Covalently binds all-trans- and 11-cis-retinal1
View neXtProt modification sites for NX_P47804
RGR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001012738.1 NP_001012740.1 NP_002912.2
ENSEMBL proteins: ENSP00000352427 ENSP00000361164 ENSP00000350823 Reactome Protein details: P47804
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005887 | integral to plasma membrane |
IEA | -- |
RGR for ontologies About GeneDecksing
RGR Antibody Products:
Assay Products for RGR: |
Protein
Domains /
Families
for RGR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RGR for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P47804ProtoNet protein and cluster: P47804 2 Blocks protein families: IPB001760 Opsin IPB001793 Retinal pigment epithelium-retinal GPCR signature
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804Similarity: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily |
Function
for RGR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804Function: Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze theisomerization of the chromophore by a retinochrome-like mechanism Genatlas biochemistry entry for RGR:retinal opsin related,(rhodopsin homolog)expressed in the retinal pigment epithelium,encoding aretinaldehyde,preferentially all-trans retinal,binding protein,G protein coupled receptor superfamily
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGR (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RGR (NM_001012722) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGR | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGR |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGR |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RGR for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Rgrtm1Hkf for RGR
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rgr):
RGR for phenotypes About GeneDecksing
|
Pathways & Interactions
for RGR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | Opsins | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 
Reactome Pathways for RGR (see all 7)
RGR for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RGR
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for RGR (P478041, 2, 3 ENSP000003524274) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
RGR for ontologies About GeneDecksing
|
Drugs & Compounds
for RGR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RGR for compounds About GeneDecksing
 Browse Tocris compounds for RGR
1 HMDB Compound for RGR About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Retinal | 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal (see all 19) | 116-31-4 | -- |
3 Novoseek chemical compound relationships for RGR gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 11-cis-retinol |
81.5 |
1 |
11852972 (1) |
| retinoid |
69 |
2 |
11086144 (1), 14742273 (1) |
| vitamin a |
51.2 |
1 |
12407145 (1) |
Search CenterWatch for drugs/clinical trials and news about RGR
|
Transcripts
for RGR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RGR gene (3 alternative transcripts): NM_001012720.1 NM_001012722.1 NM_002921.3 Unigene Cluster for RGR: Retinal G protein coupled receptor Hs.1544 [show with all ESTs]Unigene Representative Sequence: BX64103310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000359452(uc001kdd.1 uc001kdc.1 uc001kde.1) ENST00000469446
ENST00000478727 ENST00000483660 ENST00000372092(uc001kdb.1) ENST00000483771
ENST00000483744 ENST00000497161 ENST00000479725 ENST00000358110
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGR (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGR (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): RGR (NM_001012722) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGR |
Additional cDNA sequence: BC008094.1 BC011349.1 BC027987.1 BX641033.1 U14910.1 9 DOTS entries: DT.207290 DT.100754799 DT.100754798 DT.95291163 DT.95340314 DT.97804812 DT.100022272 DT.121282849 DT.70101934 24/45 AceView cDNA sequences (see all 45): BU730825 BM708524 AI858943 AW949377 BM708080 BM710540 AL713378 BM694752 BU731262 BX641033 NM_002921 BM713989 BC027987 BG820359 BG819215 AI417427 BG196839 BM686346 AL712389 BM723398 BC008094 BF528793 BG818112 BQ638073
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RGR (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for RGR
|
Expression
for RGR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RGR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RGR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RGR
SOURCE GeneReport for Unigene cluster: Hs.1544
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804Tissue specificity: Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cellsof the neural retina
SABiosciences Expression via Pathway-Focused PCR Array including RGR:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGR
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGR |
Orthologs
for RGR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for RGR gene from 4/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RGR1 |
retinal G protein coupled receptor |
67.36(n)
63.07(a) |
|
423619 NM_001031216.1 NP_001026387.1 |
lizard
(Anolis carolinensis) |
Reptilia |
RGR6 |
-- |
56(a) |
1 ↔ 1 |
GL343199.1(3386866-3413180) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.176092 |
Xenopus laevis transcribed sequence with weak similarity more |
71.97(n) |
|
BG812984.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
rgra1 |
retinal G protein coupled receptor a |
62.12(n)
57.34(a) |
|
550575 NM_001017877.1 NP_001017877.1 |
ENSEMBL Gene Tree for RGR (if available)
TreeFam Gene Tree for RGR (if available) |
Paralogs
for RGR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RGR gene
- OPN32 OPN1MW2 OPN1SW2 RHO2 OPN42 OPN1MW22 RRH2 OPN1LW2
- OPN52
1 SIMAP similar gene for RGR using alignment to 2 protein entries: RGR_HUMAN (see all proteins):RRH
RGR for paralogs About GeneDecksing
|
Genomic Variants
for RGR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RGR (86004809 - 86019716 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RGR: --
Human Gene Mutation Database (HGMD): RGR
Locus Specific Mutation Databases (LSDB): RGR
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGR |
|
Disorders
/ Diseases
for RGR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RGR for disorders About GeneDecksing
OMIM gene information: 600342
OMIM disorders: --
UniProtKB/Swiss-Prot: RGR_HUMAN, P47804
Defects in RGR are the cause of retinitis pigmentosa type 44 (RP44) [MIM:613769]. RP44 is a retinal dystrophybelonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment depositsvisible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of conephotoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As theircondition progresses, they lose their far peripheral visual field and eventually central vision as well
14  diseases for RGR: About MalaCardsretinitis retinitis pigmentosa retinitis pigmentosa-44 human granulocytic anaplasmosis
human monocytic ehrlichiosis leber congenital amaurosis pigmentary retinopathy fundus dystrophy
cone dystrophy achromatopsia ehrlichiosis retinal disease
alzheimer's disease blindness
2 diseases from the University of Copenhagen DISEASES database for RGR:Human granulocytic anaplasmosis Human monocytic ehrlichiosis 1 Novoseek disease relationship for RGR gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| retinitis pigmentosa |
77.3 |
5 |
11431696 (1), 17454745 (1), 10581022 (1), 12843338 (1) |
Human Genome Epidemiology (HuGE) Navigator: RGR (5 documents)
Export disorders for RGR gene to outside databases
|
Publications
for RGR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RGR gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with RGR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A human opsin-related gene that encodes a retinaldehyde-binding protein. (PubMed id 7947717)1, 2, 9 Shen D.... Fong H.K.W. (1994)
- Localization of the human RGR opsin gene to chromosome 10q23. (PubMed id 8641686)1, 3, 9 Chen X.N....Fong H.K. (1996)
- Mutations in RGR, encoding a light-sensitive opsin homologue, in patients with retinitis pigmentosa. (PubMed id 10581022)1, 2, 9 Morimura H.... Dryja T.P. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Alternative splicing in human retinal mRNA transcripts of an opsin-related protein. (PubMed id 7789419)1, 9 Jiang M....Fong H.K. (1995)
- Accumulation of extracellular RGR-d in Bruch's membrane and close association with drusen at intercapillary regions. (PubMed id 19450444)1, 9 Kochounian H....Fong H.K. (2009)
- In silico characterisation and chromosomal localisation of human RRH (peropsin) -- implications for opsin evolution. (PubMed id 12542842)1, 9 Bellingham J.... Foster R.G. (2003)
- Study of the involvement of the RGR, CRPB1, and CRB1 genes in the pathogenesis of autosomal recessive retinitis pigmentosa. (PubMed id 12843338)1, 9 Bernal S.... Baiget M. (2003)
- Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal pigment epithelial cells. (PubMed id 18474598)1, 9 Radu R.A....Travis G.H. (2008)
- Deposition of exon-skipping splice isoform of human retinal G protein-coupled receptor from retinal pigment epithelium into Bruch's membrane. (PubMed id 17679941)1, 9 Lin M.Y....Fong H.K. (2007)
|
External Searches for RGR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RGR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RGR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RGR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RGR | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for RGR | Genetics and Cytogenetics in Oncology and Haematology | | Mutations of the RGR gene | http://www.retina-international.org/files/sci-news/rgrmut.htm | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/RGR |
|
| | |
About This Section
| Patent Information for RGR gene:
Search GeneIP for patents involving RGR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RGR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RGR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGR | | | OriGene Protein Over-expression Lysate for RGR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RGR | | OriGene 3'-UTR Clone for RGR | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RGR | | OriGene Custom Protein Services for RGR | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RGR | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RGR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGR |
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| | | | Search Tocris compounds for RGR |
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 | | | RGR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGR |
|  |  |  | | | | ThermoFisher Antibody for RGR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGR |
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