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RGPD4 Gene

protein-coding   GIFtS: 42
GCID: GC02P108443

RANBP2-Like And GRIP Domain Containing 4

  Search for RGPD4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RANBP2-Like And GRIP Domain Containing 41 2
RGP42 3 5
RanBP2-Like And GRIP Domain-Containing Protein 42

External Ids:    HGNC: 324171   Entrez Gene: 2851902   Ensembl: ENSG000001968627   OMIM: 6127075   UniProtKB: Q7Z3J33   

Export aliases for RGPD4 gene to outside databases

Previous GC identifers: GC02U900817 GC02M087836 GC02P107810 GC02P109910


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RGPD4 Gene:
RGPD4 (RANBP2-like and GRIP domain containing 4) is a protein-coding gene. An important paralog of this gene is PPIE.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RGPD4 gene promoter:
         MEF-2A   Sp1   MEF-2   IRF-1   Nkx2-5   aMEF-2   RORalpha2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RGPD4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RGPD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.3   Ensembl cytogenetic band:  2q12.3   HGNC cytogenetic band: 2q12.3

RGPD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGPD4 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P108443:  view genomic region     (about GC identifiers)

Start:
108,443,388 bp from pter      End:
108,509,000 bp from pter
Size:
65,613 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RGPD4_HUMAN, Q7Z3J3 (See protein sequence)
Recommended Name: RanBP2-like and GRIP domain-containing protein 4  
Size: 1758 amino acids; 197289 Da
Miscellaneous: One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere
Secondary accessions: B9A029
Alternative splicing: 2 isoforms:  Q7Z3J3-1   Q7Z3J3-2   

Explore the universe of human proteins at neXtProt for RGPD4: NX_Q7Z3J3

Explore proteomics data for RGPD4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys106, Lys799, Lys1086, Lys1181, Lys1206, Lys1383, Lys1421, Lys1449
  • Modification sites at PhosphoSitePlus

  • See RGPD4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_872394.2  
    ENSEMBL proteins: 
     ENSP00000386810   ENSP00000347081  

    RGPD4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RGPD4
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RGPD4

    RGPD4 Antibody Products:

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    OriGene Custom Antibody Services for RGPD4
    Search for Antibodies for RGPD4 at Abcam
    Cloud-Clone Corp. Antibodies for RGPD4
    Search ThermoFisher Antibodies for RGPD4
    Search LSBio for Antibodies for RGPD4

    RGPD4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for RGPD4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RGPD4
    Cloud-Clone Corp. CLIAs for RGPD4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    Selected InterPro protein domains (see all 7):
     IPR000156 Ran_bind_dom
     IPR011990 TPR-like_helical
     IPR011993 PH_like_dom
     IPR001440 TPR_1
     IPR000237 GRIP

    Graphical View of Domain Structure for InterPro Entry Q7Z3J3

    ProtoNet protein and cluster: Q7Z3J3

    UniProtKB/Swiss-Prot: RGPD4_HUMAN, Q7Z3J3
    Similarity: Contains 1 GRIP domain
    Similarity: Contains 2 RanBD1 domains
    Similarity: Contains 2 TPR repeats


    RGPD4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    RGPD4 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RGPD4:
     G2 arrest  Increased S DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RGPD4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RGPD4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RGPD4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RGPD4

    miRNA
    Products:
        
    miRTarBase miRNAs that target RGPD4:
    hsa-mir-335-5p (MIRT017956)

    Block miRNA regulation of human, mouse, rat RGPD4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RGPD4 (see all 14):
    hsa-miR-548w hsa-miR-548j hsa-miR-559 hsa-miR-548h hsa-miR-548i hsa-miR-548c-5p hsa-miR-27a hsa-miR-548y
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RGPD4
    Predesigned siRNA for gene silencing in human, mouse, rat RGPD4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RGPD4

    Clone
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    OriGene clones in human, mouse for RGPD4 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RGPD4 (NM_182588)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGPD4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RGPD4

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RGPD4 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGPD4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    mitochondrion1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RGPD4 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA transport
    RNA transport

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for RGPD4):
        RNA transport


    RGPD4 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RGPD4
    Interactions:

        Search GeneGlobe Interaction Network for RGPD4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RGPD4 (Q7Z3J33 ENSP000003868104) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UVRAGQ9P2Y53, ENSP000003484554I2D: score=1 STRING: ENSP00000348455
    PLK1P533503, ENSP000003000934I2D: score=2 STRING: ENSP00000300093
    KCNA2P163893I2D: score=2 
    PRKAR1AP106443I2D: score=2 
    AIREO439183I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000042protein targeting to Golgi IEA--
    GO:0046907intracellular transport ----

    RGPD4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RGPD4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RGPD4 gene: 
    NM_182588.2  

    Unigene Cluster for RGPD4:

    RANBP2-like and GRIP domain containing 4
    Hs.449164  [show with all ESTs]
    Unigene Representative Sequence: BX537861
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000408999(uc010ywk.2 uc002tdu.3 uc010ywl.2) ENST00000354986

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RGPD4 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RGPD4 (see all 14):
    hsa-miR-548w hsa-miR-548j hsa-miR-559 hsa-miR-548h hsa-miR-548i hsa-miR-548c-5p hsa-miR-27a hsa-miR-548y
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RGPD4
    Predesigned siRNA for gene silencing in human, mouse, rat RGPD4
    Clone
    Products:
         
    OriGene clones in human, mouse for RGPD4 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RGPD4 (NM_182588)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RGPD4
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RGPD4
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RGPD4
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RGPD4
      QuantiTect SYBR Green Assays in human, mouse, rat RGPD4
      QuantiFast Probe-based Assays in human, mouse, rat RGPD4

    Additional mRNA sequence: 

    AK302921.1 BX537861.1 

    10 DOTS entries:

    DT.91842999  DT.120933586  DT.91900581  DT.92409447  DT.95274706  DT.120933571  DT.86858214  DT.120933560 
    DT.120996976  DT.87078957 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RGPD4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RGPD4 Expression
    About this image

    RGPD4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RGPD4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.449164
        Custom PCR Arrays for RGPD4
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RGPD4
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat RGPD4
    QuantiTect SYBR Green Assays in human, mouse, rat RGPD4
    QuantiFast Probe-based Assays in human, mouse, rat RGPD4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGPD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RGPD4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ranbp21 RAN binding protein 2 87.87(n)
    88.67(a)
      19386  NM_011240.3  NP_035370.2 
    chicken
    (Gallus gallus)
    Aves RANBP21 RAN binding protein 2 71.02(n)
    68.77(a)
      418730  XM_416929.4  XP_416929.4 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    42(a)
    1 → many
    3(107454117-107504389)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ranbp21 RAN binding protein 2 66.69(n)
    62.64(a)
      100134999  XM_002937658.2  XP_002937704.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch1073-55a19.21 si:ch1073-55a19.2 56.71(n)
    55.19(a)
      100317326  XM_005169115.1  XP_005169172.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG50716
    --
    14(a)
    1 → many
    3R(21444136-21446401)
    worm
    (Caenorhabditis elegans)
    Secernentea T22F3.126
    Y17G9B.46
    Protein Y17G9B.4 (Y17G9B.4) mRNA, complete cds
    7(a)
    13(a)
    many ↔ many
    many ↔ many
    V(3589029-3592199) WBGene00044705
    IV(4752094-4753230) WBGene00021201


    ENSEMBL Gene Tree for RGPD4 (if available)
    TreeFam Gene Tree for RGPD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RGPD4 gene
    RGPD31 2  RGPD11 2  RGPD21 2  RGPD81 2  RGPD51 2  RGPD61 2  PPIE2  PPIAL4C2  
    RANBP22  PPIF2  PPIA2  PPIAL4D2  PPIAL4A2  PPIAL4G2  PPIAL4B2  
    8 SIMAP similar genes for RGPD4 using alignment to 2 protein entries:     RGPD4_HUMAN (see all proteins):
    RGPD3    RGPD1    RGPD2    RGPD5    RGPD6    RGPD8
    RANBP1    RANBP2

    RGPD4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RGPD4 (see all 482)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs50232931,2
    C--108445458(+) GCCTCG/TACCCG 1 -- int11Minor allele frequency- T:0.00NA 2
    rs50232941,2
    --108445660(+) GCCTCG/CATGGC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs754712181,2
    F--108445727(+) GGCCTC/TGACCC 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1866367961,2
    --108445781(+) TGGGCA/GCTGCT 1 -- int10--------
    rs1910969351,2
    --108445796(+) GGCGCA/GCTCTG 1 -- int10--------
    rs16598971,2
    C--108445908(-) CGGGTC/AGAGGC 1 -- int12Minor allele frequency- A:0.00NA 4
    rs741802931,2
    C--108445912(+) CGACCC/TGGCCC 1 -- int12Minor allele frequency- T:0.25NA 4
    rs16239101,2
    C,H--108445917(-) CCGCCG/CGGCCA 1 -- int11Minor allele frequency- C:0.00NA 2
    rs105477901,2
    C--108446800(+) AGCTT-/A/AA  
            
    AAAAA
    1 -- int10--------
    rs3725502201,2
    C--108446800(+) AAGCT-/AAAAAAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for RGPD4 (108443388 - 108509000 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RGPD4 (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720498CNV Deletion23290073
    esv1536919CNV Deletion17803354
    esv2720482CNV Deletion23290073
    dgv724e199CNV Deletion23128226
    esv1116837CNV Insertion17803354
    esv2475213CNV Loss19546169
    esv995182CNV Loss20482838
    dgv61n68CNV Gain17160897
    nsv829610CNV Gain20364138
    nsv829611CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RGPD4
    DNA2.0 Custom Variant and Variant Library Synthesis for RGPD4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612707    OMIM disorders: --


    RGPD4 for disorders           About GeneDecksing


    Export disorders for RGPD4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RGPD4 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RGPD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2, 3 Hillier L.W.... Wilson R.K. (Nature 2005)
    2. Complex genomic rearrangements lead to novel primate gene function. (PubMed id 15710750)1, 2, 3 Ciccarelli F.D.... Bork P. (Genome Res. 2005)
    3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. (PubMed id 19596235)1 Svendsen J.M.... Harper J.W. (Cell 2009)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 285190 HGNC: 32417 Ensembl:ENSG00000196862 euGenes: HUgn285190 ECgene: RGPD4 Kegg: 285190
    H-InvDB: RGPD4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RGPD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RGPD4 gene:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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