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Aliases for RGPD1 Gene

Aliases for RGPD1 Gene

  • RANBP2-Like And GRIP Domain Containing 1 2 3 5
  • Ran-Binding Protein 2-Like 6 3 4
  • RanBP2-Like 6 3 4
  • RanBP2L6 3 4
  • RGP1 3 4
  • RANBP2-Like And GRIP Domain-Containing Protein 1/2 3
  • Ran-Binding Protein 2-Like 2/6 3
  • RanBP2-Like 2/6 3
  • RanBP2L2 3
  • RGPD2 3

External Ids for RGPD1 Gene

Previous GeneCards Identifiers for RGPD1 Gene

  • GC02P087013
  • GC02U900966
  • GC02P086994
  • GC02P087135

Summaries for RGPD1 Gene

GeneCards Summary for RGPD1 Gene

RGPD1 (RANBP2-Like And GRIP Domain Containing 1) is a Protein Coding gene. Among its related pathways are RNA transport. An important paralog of this gene is RGPD8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RGPD1 Gene

Genomics for RGPD1 Gene

Regulatory Elements for RGPD1 Gene

Enhancers for RGPD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RGPD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RGPD1 Gene

86,907,953 bp from pter
87,013,981 bp from pter
106,029 bases
Plus strand

Genomic View for RGPD1 Gene

Genes around RGPD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RGPD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RGPD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RGPD1 Gene

Proteins for RGPD1 Gene

  • Protein details for RGPD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RANBP2-like and GRIP domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • P0C839
    • Q68DN6
    • Q6V1X0

    Protein attributes for RGPD1 Gene

    1748 amino acids
    Molecular mass:
    196662 Da
    Quaternary structure:
    No Data Available
    • One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere.

neXtProt entry for RGPD1 Gene

Proteomics data for RGPD1 Gene at MOPED

Post-translational modifications for RGPD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RGPD1 Gene

No data available for DME Specific Peptides for RGPD1 Gene

Domains & Families for RGPD1 Gene

Gene Families for RGPD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 GRIP domain.
  • Contains 3 TPR repeats.
  • Contains 1 GRIP domain.
  • Contains 2 RanBD1 domains.
  • Contains 3 TPR repeats.
genes like me logo Genes that share domains with RGPD1: view

No data available for Suggested Antigen Peptide Sequences for RGPD1 Gene

Function for RGPD1 Gene

Phenotypes for RGPD1 Gene

GenomeRNAi human phenotypes for RGPD1:
genes like me logo Genes that share phenotypes with RGPD1: view

Animal Model Products

CRISPR Products

miRNA for RGPD1 Gene

miRTarBase miRNAs that target RGPD1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RGPD1 Gene

Localization for RGPD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RGPD1 Gene

Pathways & Interactions for RGPD1 Gene

SuperPathways for RGPD1 Gene

Superpath Contained pathways
1 RNA transport
genes like me logo Genes that share pathways with RGPD1: view

Pathways by source for RGPD1 Gene

1 KEGG pathway for RGPD1 Gene

Interacting Proteins for RGPD1 Gene

Gene Ontology (GO) - Biological Process for RGPD1 Gene


No data available for SIGNOR curated interactions for RGPD1 Gene

Drugs & Compounds for RGPD1 Gene

No Compound Related Data Available

Transcripts for RGPD1 Gene

mRNA/cDNA for RGPD1 Gene

(10) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RGPD1 Gene

RANBP2-like and GRIP domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RGPD1 Gene

No ASD Table

Relevant External Links for RGPD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RGPD1 Gene

mRNA expression in normal human tissues for RGPD1 Gene

mRNA differential expression in normal tissues according to GTEx for RGPD1 Gene

This gene is overexpressed in Testis (x16.4), Cervix - Endocervix (x13.6), and Pituitary (x5.5).

Protein differential expression in normal tissues from HIPED for RGPD1 Gene

This gene is overexpressed in Nasal epithelium (57.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RGPD1 Gene

SOURCE GeneReport for Unigene cluster for RGPD1 Gene Hs.728970

genes like me logo Genes that share expression patterns with RGPD1: view

Protein tissue co-expression partners for RGPD1 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RGPD1 Gene

Orthologs for RGPD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RGPD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RANBP2 35
  • 85.06 (n)
  • 83.97 (a)
(Mus musculus)
Mammalia Ranbp2 35
  • 87.81 (n)
  • 88.06 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 75 (a)
-- 36
  • 79 (a)
(Pan troglodytes)
Mammalia -- 36
  • 95 (a)
(Gallus gallus)
Aves RANBP2 35
  • 71.13 (n)
  • 68.91 (a)
-- 36
  • 43 (a)
-- 36
  • 58 (a)
-- 36
  • 48 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 41 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ranbp2 35
  • 66.51 (n)
  • 62.43 (a)
(Danio rerio)
Actinopterygii si:ch1073-55a19.2 35
  • 56.6 (n)
  • 55.08 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5071 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea T22F3.12 36
  • 7 (a)
Y17G9B.4 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 4 (a)
Species with no ortholog for RGPD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RGPD1 Gene

Gene Tree for RGPD1 (if available)
Gene Tree for RGPD1 (if available)

Paralogs for RGPD1 Gene

Paralogs for RGPD1 Gene

(8) SIMAP similar genes for RGPD1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with RGPD1: view

Variants for RGPD1 Gene

Sequence variations from dbSNP and Humsavar for RGPD1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1828964 -- 87,001,868(-) actga(C/G)cccag intron-variant, utr-variant-3-prime
rs2918648 -- 86,982,606(-) AGGAT(A/G)TGCTG intron-variant
rs2919164 -- 86,974,059(-) AAATA(A/T)AAAAA intron-variant
rs2943623 -- 86,965,778(-) cgcag(C/T)agctc intron-variant
rs4971894 -- 86,951,944(-) ATGGA(A/G)CCAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RGPD1 Gene

Variant ID Type Subtype PubMed ID
esv25494 CNV Gain 19812545
nsv7316 OTHER Inversion 18451855
nsv874473 CNV Gain 21882294
dgv1214e1 CNV Complex 17122850
nsv874474 CNV Loss 21882294
nsv519198 CNV Loss 19592680
nsv874475 CNV Loss 21882294
esv33176 CNV Loss 17666407
dgv1215e1 CNV Complex 17122850
nsv2815 CNV Loss 18451855
nsv10064 CNV Gain 18304495
nsv498927 CNV Loss 21111241
nsv508849 CNV Insertion 20534489
nsv516958 CNV Gain+Loss 19592680
dgv61n16 CNV Deletion 17901297
nsv834287 CNV Gain 17160897
nsv834288 CNV Gain 17160897
nsv874574 CNV Gain 21882294
dgv4227n71 CNV Loss 21882294
nsv874577 CNV Gain 21882294
nsv10070 CNV Gain 18304495
nsv820913 CNV Deletion 20802225
esv27348 CNV Gain 19812545
nsv874578 CNV Gain 21882294
nsv829493 CNV Gain 20364138
nsv829494 CNV Gain 20364138
nsv874580 CNV Loss 21882294
esv1743470 CNV Deletion 17803354
nsv10071 CNV Gain 18304495

Variation tolerance for RGPD1 Gene

Gene Damage Index Score: 1.84; 34.58% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RGPD1 Gene

Disorders for RGPD1 Gene

Relevant External Links for RGPD1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RGPD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RGPD1 Gene

Publications for RGPD1 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 2 3 4 67
  2. Complex genomic rearrangements lead to novel primate gene function. (PMID: 15710750) Ciccarelli F.D. … Bork P. (Genome Res. 2005) 2 3
  3. Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. (PMID: 25963833) Drissi R. … Boisvert F.M. (Mol. Cell Proteomics 2015) 3
  4. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  5. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 3

Products for RGPD1 Gene

Sources for RGPD1 Gene