RGPD1 Gene
protein-coding GIFtS: 43
GCID: GC02P087135
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|
RANBP2-like and GRIP domain containing 1
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Aliases
for RGPD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RANBP2-Like And GRIP Domain Containing 11 2 | | RanBP2L63 | | RGP11 2 3 5 | | RanBP2-Like 2/62 | | Ran-Binding Protein 2-Like 62 3 | | RANBP2-Like And GRIP Domain-Containing Protein 12 | | RanBP2-Like 62 3 | | RANBP2-Like And GRIP Domain-Containing Protein 1/22 | | RGPD22 | | RANBP2L63 | | RanBP2L22 | | RanBP2L63 | | Ran-Binding Protein 2-Like 2/62 | | |
Export aliases for RGPD1 gene to outside databasesPrevious GC identifers: GC02P087013 GC02U900966 GC02P086994 |
Summaries
for RGPD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RGPD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RGPD1 gene promoter:
TBP ISGF-3 AML1a Sp1 FOXL1 Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for RGPD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGPD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p11.2 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p11.2RGPD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P087135: view genomic region
(about GC identifiers)
Start:
|
87,135,076 bp from pter |
End:
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87,241,104 bp from pter |
Size:
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106,029 bases |
Orientation:
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plus strand |
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Proteins
for RGPD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RGPD1_HUMAN, P0DJD0 (See
protein sequence)Recommended Name: RANBP2-like and GRIP domain-containing protein 1 Size: 1748 amino acids; 196662 Da
Miscellaneous: One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere
Secondary accessions: P0C839 Q68DN6 Q6V1X0Explore the universe of human proteins at neXtProt for RGPD1: NX_P0DJD0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0DJD0
RGPD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001019628.3
ENSEMBL proteins: ENSP00000453170 ENSP00000402729 ENSP00000386808 ENSP00000381253 ENSP00000397931
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
-- | -- |
RGPD1 for ontologies About GeneDecksing
RGPD1 Antibody Products:
Assay Products for RGPD1: |
Protein
Domains /
Families
for RGPD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RGPD1 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry P0DJD0ProtoNet protein and cluster: P0DJD0 UniProtKB/Swiss-Prot: RGPD1_HUMAN, P0DJD0Similarity: Contains 1 GRIP domainSimilarity: Contains 2 RanBD1 domainsSimilarity: Contains 3 TPR repeats |
Function
for RGPD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RGPD1 (NM_001024457) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGPD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGPD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGPD1 |
|
Pathways & Interactions
for RGPD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RGPD1
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for RGPD1 (ENSP000003812534) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000042 | protein targeting to Golgi |
IEA | -- | | GO:0046907 | intracellular transport |
-- | -- |
RGPD1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RGPD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RGPD1
Search CenterWatch for drugs/clinical trials and news about RGPD1
|
Transcripts
for RGPD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RGPD1 gene: NM_001024457.3 Unigene Cluster for RGPD1: RANBP2-like and GRIP domain containing 1 Hs.728970 [show with all ESTs]Unigene Representative Sequence: CR7493305 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000559485(uc021vkh.1) ENST00000428128 ENST00000409776(uc010fgv.3 uc002ssc.3)
ENST00000398193 ENST00000456925
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RGPD1 (NM_001024457) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RGPD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGPD1 |
Additional cDNA sequence: AF086151.1 AK302429.1 AK303443.1 CR749330.1 24/29 DOTS entries (see all 29): DT.99940910 DT.309339 DT.121025807 DT.95274717 DT.121024439 DT.121024440 DT.121025771 DT.121025763 DT.121024469 DT.121025674 DT.121025795 DT.95274695 DT.121024457 DT.121025755 DT.40291677 DT.120954923 DT.120968095 DT.87078349 DT.91842999 DT.109397 DT.110533 DT.120968102 DT.121024458 DT.121025659 2 AceView cDNA sequences: BV203127 BI008704
GeneLoc Exon Structure
|
Expression
for RGPD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RGPD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RGPD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RGPD1
SOURCE GeneReport for Unigene cluster: Hs.728970
SABiosciences Custom PCR Arrays for RGPD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGPD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RGPD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGPD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGPD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGPD1 |
Orthologs
for RGPD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RGPD1 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for RGPD1 (if available)
TreeFam Gene Tree for RGPD1 (if available) |
Paralogs
for RGPD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RGPD1 gene
- RGPD21 2 RGPD41 2 RGPD31 2 RGPD81 2 RGPD51 2 RGPD61 2 RANBP22 RANBP12
8 SIMAP similar genes for RGPD1 using alignment to 5 protein entries: RGPD1_HUMAN (see all proteins):RGPD2 RGPD3 RGPD4 RGPD6 RGPD5 RGPD8
RANBP2 RANBP1
RGPD1 for paralogs About GeneDecksing
|
Genomic Variants
for RGPD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RGPD1 (87135076 - 87241104 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 38 variations for RGPD1
15/36 CNVs (see all 36): 35864 89770 89768 89774 89772 89773 89777 89771 89761 78622 89759 3374 7283 89778 68078
2 Indels: 40344 26756 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGPD1 |
|
Disorders
/ Diseases
for RGPD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RGPD1 for disorders About GeneDecksing
OMIM gene information: 612704
OMIM disorders: --
2  diseases for RGPD1: About MalaCardspseudosarcomatous fibromatosis fibromatosis
1 disease from the University of Copenhagen DISEASES database for RGPD1:Pseudosarcomatous fibromatosis Human Genome Epidemiology (HuGE) Navigator: RGPD1 (3 documents)
Export disorders for RGPD1 gene to outside databases
|
Publications
for RGPD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RGPD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RGPD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2, 3 Hillier L.W....Wilson R.K. (2005)
- Complex genomic rearrangements lead to novel primate gene function. (PubMed id 15710750)1, 3 Ciccarelli F.D.... Bork P. (2005)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
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External Searches for RGPD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing RGPD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RGPD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RGPD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RGPD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RGPD1 gene:
Search GeneIP for patents involving RGPD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RGPD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RGPD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGPD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RGPD1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RGPD1 | | OriGene 3'-UTR Clone for RGPD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RGPD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | RGPD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RGPD1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RGPD1 |
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