Aliases for RGP1 Gene
External Ids for RGP1 Gene
Previous HGNC Symbols for RGP1 Gene
GeneCards Summary for RGP1 Gene
RGP1 (RGP1 Homolog, RAB6A GEF Complex Partner 1) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Vesicle-mediated transport. GO annotations related to this gene include Rab GTPase binding and Rab guanyl-nucleotide exchange factor activity.
UniProtKB/Swiss-Prot for RGP1 Gene
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.