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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RGMB Gene

protein-coding   GIFtS: 58
GCID: GC05P098132

RGM Domain Family, Member B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RGM Domain Family, Member B1 2
DRAGON2 3 5
DRG11-Responsive Axonal Guidance And Outgrowth Of Neurite2 3
Repulsive Guidance Molecule B2
RGM Domain Family Member B2

External Ids:    HGNC: 268961   Entrez Gene: 2857042   Ensembl: ENSG000001741367   OMIM: 6126875   UniProtKB: Q6NW403   

Export aliases for RGMB gene to outside databases

Previous GC identifers: GC05P098181 GC05P093292


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RGMB Gene:
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA,
MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 (PubMed
15671031)).(supplied by OMIM, Apr 2009)

GeneCards Summary for RGMB Gene: 
RGMB (RGM domain family, member B) is a protein-coding gene. Diseases associated with RGMB include chronic monocytic leukemia, and dermatomycosis, and among its related super-pathways are Axon guidance and DCC mediated attractive signaling. GO annotations related to this gene include identical protein binding. An important paralog of this gene is RGMA.

UniProtKB/Swiss-Prot: RGMB_HUMAN, Q6NW40
Function: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the
developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates
BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth

Gene Wiki entry for RGMB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_034772.6  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RGMB gene promoter:
         SRY   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RGMB promoter sequence
   Search SABiosciences Chromatin IP Primers for RGMB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGMB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q15   Ensembl cytogenetic band:  5q15   HGNC cytogenetic band: 5q21.1

RGMB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGMB gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P098132:  view genomic region     (about GC identifiers)

Start:
98,104,354 bp from pter      End:
98,134,347 bp from pter
Size:
29,994 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RGMB_HUMAN, Q6NW40 (See protein sequence)
Recommended Name: RGM domain family member B precursor  
Size: 437 amino acids; 47547 Da
Subunit: Homooligomer (By similarity). Interacts with DRGX (By similarity). Interacts with BMP2 and BMP4 (By
similarity). Interacts with the BMP type I receptors ACVR1, BMPR1A and BMPR1B and with the BMP type II receptor
ACVR2B (By similarity)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Membrane raft (By similarity)
Sequence caution: Sequence=AAH67736.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAC11268.1; Type=Miscellaneous discrepancy; Note=Intron retention;
3 PDB 3D structures from and Proteopedia for RGMB:
4BQ6 (3D)        4BQ7 (3D)        4BQ8 (3D)    
Secondary accessions: D6R9A0 Q8NC92

Explore the universe of human proteins at neXtProt for RGMB: NX_Q6NW40

Explore proteomics data for RGMB at MOPED 

Post-translational modifications:

  • UniProtKB: GPI-anchored (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6NW40

  • RGMB Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RGMB Protein Expression
    REFSEQ proteins: NP_001012779.2  
    ENSEMBL proteins: 
     ENSP00000308219   ENSP00000423256  
    Reactome Protein details: Q6NW40
    Human Recombinant Protein Products for RGMB: 
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    Cloud-Clone Corp. Proteins for RGMB 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment ISS--
    GO:0045121membrane raft IEA--
    GO:0046658anchored to plasma membrane ISS--

    RGMB for ontologies           About GeneDecksing



    RGMB Antibody Products: 
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    Cloud-Clone Corp. CLIAs for RGMB


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR009496 RGM_C
     IPR010536 RGM_N

    Graphical View of Domain Structure for InterPro Entry Q6NW40

    ProtoNet protein and cluster: Q6NW40

    1 Blocks protein domain: IPB009496 Repulsive guidance molecule

    UniProtKB/Swiss-Prot: RGMB_HUMAN, Q6NW40
    Similarity: Belongs to the repulsive guidance molecule (RGM) family


    RGMB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RGMB_HUMAN, Q6NW40
    Function: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the
    developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates
    BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042802identical protein binding ISS--
         
    RGMB for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RGMB:
     Synthetic lethal with c-Myc af 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rgmb):
     mortality/aging 

    RGMB for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RGMB 
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    miRNA
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    8/91 QIAGEN miScript miRNA Assays for microRNAs that regulate RGMB (see all 91):
    hsa-miR-411* hsa-miR-548j hsa-miR-140-5p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-93 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidRGMB 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RGMB About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Axon guidance
    Axon guidance0.69
    Developmental Biology0.69
    2Netrin-1 signaling
    Netrin-1 signaling0.33
    3Signaling by BMP
    BMP receptor signaling0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for RGMB
        BMP receptor signaling

    3        Reactome Pathways for RGMB
        Developmental Biology
    Netrin-1 signaling
    Axon guidance



    RGMB for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RGMB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/28 Interacting proteins for RGMB (Q6NW403 ENSP000003082194) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BMPR1AP368943I2D: score=1 
    BAMBIENSP000003646834STRING: ENSP00000364683
    BMP2ENSP000003681044STRING: ENSP00000368104
    BMP4ENSP000002454514STRING: ENSP00000245451
    BMPR1BENSP000002645684STRING: ENSP00000264568
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007155cell adhesion ISS--
    GO:0007165signal transduction ISS--
    GO:0007411axon guidance TAS--
    GO:0030509BMP signaling pathway ISS--
    GO:0045893positive regulation of transcription, DNA-dependent ISS--

    RGMB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RGMB

    Search CenterWatch for drugs/clinical trials and news about RGMB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RGMB gene (2 alternative transcripts): 
    NM_173670.2  NM_001012761.2  

    Unigene Cluster for RGMB:

    RGM domain family, member B
    Hs.526902  [show with all ESTs]
    Unigene Representative Sequence: NM_001012761
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504776 ENST00000505265 ENST00000434027(uc003knb.2) ENST00000308234(uc003knc.3)
    ENST00000507054 ENST00000513185 ENST00000508978
    miRNA
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    8/91 QIAGEN miScript miRNA Assays for microRNAs that regulate RGMB (see all 91):
    hsa-miR-411* hsa-miR-548j hsa-miR-140-5p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-93 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidRGMB 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGMB
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGMB

    Additional mRNA sequence: 

    AK054622.1 AK074887.1 AK125284.1 BC020513.1 BC044231.1 BC067736.1 

    5 DOTS entries:

    DT.414777  DT.203356  DT.40290433  DT.75147495  DT.97771808 

    24/133 AceView cDNA sequences (see all 133):

    BQ021208 AI383006 BM706050 BF724316 BG741703 BI966210 AI468297 CB127183 
    AI740728 N35732 AI308931 BC020513 AA470819 BX109418 AK054622 N35457 
    BG675151 BE855765 BQ212600 AI087846 CB118185 AI919210 BF724900 CA443601 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RGMB    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4
    SP1:        -     -               
    SP2:              -               
    SP3:                              


    ECgene alternative splicing isoforms for RGMB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RGMB expression in normal human tissues (normalized intensities)      RGMB embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGTCTTTA
    RGMB Expression
    About this image


    RGMB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Peripheral Nervous System (Nervous System)
             Human Schwann Cells (HSC)   
     
     Inner Cell Mass (Early Embryonic Tissues)
             Line H7 (WA07)
     
     Chorion (Extraembryonic Tissues)
             chorion villus cells   
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Fibroblast (Uncategorized)
             X-gene Foreskin Fibroblasts   

    See RGMB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RGMB

    SOURCE GeneReport for Unigene cluster: Hs.526902
        SABiosciences Custom PCR Arrays for RGMB
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RGMB gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rgmb1 , 5 RGM domain family, member B1, 5 87.91(n)1
    90.3(a)1
      17 (8.96 cM)5
    687991  NM_178615.31  NP_848730.21 
     158062535 
    chicken
    (Gallus gallus)
    Aves RGMB1 RGM domain family, member B 74.47(n)
    76.36(a)
      427277  XM_424860.3  XP_424860.3 
    lizard
    (Anolis carolinensis)
    Reptilia RGMB6
    RGM domain family, member B
    74(a)
    1 ↔ 1
    2(27342180-27386383)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC758142 hypothetical protein MGC75814 78.34(n)    BC061325.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rgmb1 RGM domain family, member B 68.13(n)
    69.33(a)
      414273  NM_001001727.1  NP_001001727.1 
    worm
    (Caenorhabditis elegans)
    Secernentea drag-11 Protein DRAG-1 44.32(n)
    34.47(a)
      190602  NM_058480.3  NP_490881.3 


    ENSEMBL Gene Tree for RGMB (if available)
    TreeFam Gene Tree for RGMB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RGMB gene
    RGMA2  HFE22  
    2 SIMAP similar genes for RGMB using alignment to 2 protein entries:     RGMB_HUMAN (see all proteins):
    RGMA    HFE2

    RGMB for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/448 SNPs in RGMB are shown (see all 448)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807186651,2
    --98103149(+) AATGTC/TCAAGT 1 -- us2k10--------
    rs1863771471,2
    --98103225(+) ATGATC/GTGATG 1 -- us2k10--------
    rs1912316661,2
    --98103361(+) AGCAGC/GAGAGG 1 -- us2k10--------
    rs799122441,2
    C,F--98103443(+) CATCAT/GTATTT 1 -- us2k11Minor allele frequency- G:0.03EA 120
    rs1380629531,2
    C--98103621(+) TGGGG-/TTTTTT 1 -- us2k10--------
    rs1388286751,2
    C--98103752(+) AGGTG-/AAAAAA 1 -- us2k10--------
    rs1818929931,2
    --98103759(+) AAAAAC/TACTAA 1 -- us2k10--------
    rs13632981,2
    C,F,H--98103849(+) AATTAT/ATGCCT 1 -- us2k1 tfbs314Minor allele frequency- A:0.00NS EA NA WA CSA 548
    rs77312221,2
    C,F,H--98104055(+) AGCTGG/CAGAGG 1 -- us2k15Minor allele frequency- C:0.01NS EA WA 516
    rs1869170061,2
    --98104064(+) GGGTCA/GTAGAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RGMB (98104354 - 98134347 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RGMB:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv882414CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RGMB
    DNA2.0 Custom Variant and Variant Library Synthesis for RGMB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612687    OMIM disorders: --

    8 diseases for RGMB:    About MalaCards
    chronic monocytic leukemia    dermatomycosis    basilar artery occlusion    spinal cord injury
    monocytic leukemia    breast cancer    neuronitis    leukemia

    2 diseases from the University of Copenhagen DISEASES database for RGMB:
    Dermatomycosis     Chronic monocytic leukemia

    RGMB for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: RGMB (1 document)

    Export disorders for RGMB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RGMB gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with RGMB)
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    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Structure of the repulsive guidance molecule (RGM)-neo genin signaling hub. (PubMed id 23744777)1 Bell C.H....Siebold C. (2013)
    4. Repulsive guidance molecule B (RGMB) plays negative ro les in breast cancer by coordinating BMP signaling. (PubMed id 22415859)1 Li J....Jiang W.G. (2012)
    5. Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of pr ostate cancer cells. (PubMed id 22076499)1 Li J....Jiang W.G. (2012)
    6. Potential prognostic value of repulsive guidance mole cules in breast cancer. (PubMed id 21617229)1 Li J....Jiang W.G. (2011)
    7. Variants in several genomic regions associated with a sperger disorder. (PubMed id 21182207)1 Salyakina D....Pericak-Vance M.A. (2010)
    8. Repulsive guidance molecule b inhibits neurite growth and is increased after spinal cord injury. (PubMed id 19324014)2 Liu X.... Yamashita T. (2009)
    9. DRAGON, a bone morphogenetic protein co-receptor. (PubMed id 15671031)1 Samad T.A....Woolf C.J. (2005)
    10. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 285704 HGNC: 26896 AceView: RGMB Ensembl:ENSG00000174136 euGenes: HUgn285704
    ECgene: RGMB H-InvDB: RGMB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RGMB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RGMB gene:
    Search GeneIP for patents involving RGMB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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