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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RGL2 Gene

protein-coding   GIFtS: 54
GCID: GC06M033259

ral guanine nucleotide dissociation stimulator-like 2

(Previous names: RAB2, member RAS oncogene family-like )
(Previous symbol: RAB2L)
 Explore 7 diseases affiliated with
RGL2 via our new
 Human Malady Compendium 
Biological research products
for RGL2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ral Guanine Nucleotide Dissociation Stimulator-Like 21 2     RalGDS-Like Factor2 3
RAB2L1 2 3 5     Ras-Associated Protein RAB2L2 3
HKE1.51 2     RAB2, Member RAS Oncogene Family-Like1
KE1.51 2     GDS-Related Protein2
RalGDS-Like 22 3     

External Ids:    HGNC: 97691   Entrez Gene: 58632   Ensembl: ENSG000002374417   OMIM: 6023065   UniProtKB: O152113   

Export aliases for RGL2 gene to outside databases

Previous GC identifers: GC06M033307 GC06M033367 GC06M033001


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RGL2_HUMAN, O15211
Function: Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the
GTP-bound form of Rap 1A and H-Ras in vitro (By similarity)

Gene Wiki entry for RGL2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167245.1  NT_167247.1  NT_167248.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RGL2 gene promoter:
         E2F-4   E2F-3a   E2F-5   Sp1   Pax-5   CUTL1   E2F-2   E2F   E2F-1   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RGL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RGL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RGL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.32   HGNC cytogenetic band: 6p21.3

RGL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RGL2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M033259:  view genomic region     (about GC identifiers)

Start:
33,259,431 bp from pter      End:
33,267,176 bp from pter
Size:
7,746 bases      Orientation:
minus strand

4 alternative locations:
Chr6-,ALT_REF_LOCI_5 33,344,598-33,352,343      Chr6-,ALT_REF_LOCI_2 33,181,041-33,227,974      Chr6-,ALT_REF_LOCI_3 33,237,360-33,256,143     
Chr6-,ALT_REF_LOCI_6 33,188,277-33,231,600     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RGL2_HUMAN, O15211 (See protein sequence)
Recommended Name: Ral guanine nucleotide dissociation stimulator-like 2  
Size: 777 amino acids; 83549 Da
Subunit: Interacts with SAMD9
Secondary accessions: Q5STK0 Q9Y3F3

Explore the universe of human proteins at neXtProt for RGL2: NX_O15211

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15211

  • RGL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001230667.1  NP_004752.1  

    ENSEMBL proteins: 
     ENSP00000420211   ENSP00000392918   ENSP00000403070  

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    Uscn Proteins for RGL2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005622intracellular IEA--


    RGL2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RGL2 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR008937 Ras_GEF
     IPR023578 Ras_GEF_dom
     IPR001895 RasGRF_CDC25
     IPR000159 Ras-assoc
     IPR019804 Ras_G-nucl-exch_fac_CS

    Graphical View of Domain Structure for InterPro Entry O15211

    ProtoNet protein and cluster: O15211

    2 Blocks protein families:
    IPB000159 RA domain
    IPB001895 Guanine-nucleotide dissociation stimulator CDC25


    UniProtKB/Swiss-Prot: RGL2_HUMAN, O15211
    Similarity: Contains 1 N-terminal Ras-GEF domain
    Similarity: Contains 1 Ras-associating domain
    Similarity: Contains 1 Ras-GEF domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RGL2_HUMAN, O15211
    Function: Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the
    GTP-bound form of Rap 1A and H-Ras in vitro (By similarity)

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate RGL2 (see all 11):
    hsa-miR-142-3p hsa-miR-328 hsa-miR-27a hsa-miR-324-3p hsa-miR-4255 hsa-miR-128 hsa-miR-3681* hsa-miR-196a
    SwitchGear 3'UTR luciferase reporter plasmidRGL2 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005085guanyl-nucleotide exchange factor activity ----
    GO:0005088Ras guanyl-nucleotide exchange factor activity NAS8976381


    RGL2 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for RGL2:
     Decreased nuclei size in G2M  Increased HPV18 LCR reporter a 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1G-protein signaling K-RAS regulation pathway
    G-protein signaling K-RAS regulation pathway1.00
    G-protein signaling_K-RAS regulation pathway0.96
    2G-protein signaling N-RAS regulation pathway
    G-protein signaling N-RAS regulation pathway1.00
    G-protein signaling_N-RAS regulation pathway0.83
    3Cytoskeleton remodeling_RalB regulation pathway
    Cytoskeleton remodeling RalA regulation pathway0.23
    Cytoskeleton remodeling_RalA regulation pathway0.23

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    3 EMD Millipore Pathways for RGL2
        G-protein signaling K-RAS regulation pathway
    G-protein signaling N-RAS regulation pathway
    Cytoskeleton remodeling RalA regulation pathway


    3 GeneGo (Thomson Reuters) Pathways for RGL2
        G-protein signaling K-RAS regulation pathway
    G-protein signaling N-RAS regulation pathway
    Cytoskeleton remodeling RalA regulation pathway



    RGL2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RGL2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/15 Interacting proteins for RGL2 (O152113 ENSP000004202114) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HRASP011123, ENSP000003098454I2D: score=5 STRING: ENSP00000309845
    RAP1BP612243, ENSP000002505594I2D: score=4 STRING: ENSP00000250559
    CCDC90BQ9GZT63I2D: score=4 
    EEF1GP266413I2D: score=4 
    KAT5Q929933I2D: score=4 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction ----
    GO:0007265Ras protein signal transduction NAS8976381
    GO:0051056regulation of small GTPase mediated signal transduction IEA--


    RGL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RGL2

    3 HMDB Compounds for RGL2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about RGL2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RGL2 gene (2 alternative transcripts): 
    NM_001243738.1  NM_004761.4  

    Unigene Cluster for RGL2:

    Ral guanine nucleotide dissociation stimulator-like 2
    Hs.509622  [show with all ESTs]
    Unigene Representative Sequence: NM_004761
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491168 ENST00000483151 ENST00000437840(uc010jur.3) ENST00000466866(uc003odu.3)
    ENST00000497454(uc003odv.3 uc003odw.3 uc011drb.2) ENST00000471319
    ENST00000476616 ENST00000478610 ENST00000494550 ENST00000485077 ENST00000460988
    ENST00000425946 ENST00000444031

    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate RGL2 (see all 11):
    hsa-miR-142-3p hsa-miR-328 hsa-miR-27a hsa-miR-324-3p hsa-miR-4255 hsa-miR-128 hsa-miR-3681* hsa-miR-196a
    SwitchGear 3'UTR luciferase reporter plasmidRGL2 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RGL2 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: RGL2 (NM_004761)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RGL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RGL2

    Additional cDNA sequence: 

    AK095967.1 AL050259.1 BC000316.1 BC005037.1 BC032681.1 BX648015.1 D85757.1 U68142.1 

    23 DOTS entries:

    DT.99998208  DT.318123  DT.91809717  DT.121364717  DT.95340907  DT.99947740  DT.75124524  DT.95340908 
    DT.100789247  DT.121364627  DT.100728258  DT.100789254  DT.95340990  DT.100709336  DT.100789249  DT.100789250 
    DT.100789253  DT.97781926  DT.100029308  DT.100760268  DT.121364598  DT.121364720  DT.80100030 

    24/315 AceView cDNA sequences (see all 315):

    BM469731 AA699480 BU785457 BC005037 BU902962 BM792732 AA458470 CB215713 
    CF125267 BP361069 BX648015 AA639686 BQ955127 AA505865 AA687824 CA417539 
    BM769947 BQ884252 BQ011541 AA526375 AL047730 AL050259 BM698131 BQ231500 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RGL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAAGGGCCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RGL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RGL2

    SOURCE GeneReport for Unigene cluster: Hs.509622
        SABiosciences Custom PCR Arrays for RGL2
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RGL2 gene from 4/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia RGL26
    --
    53(a)
    1 ↔ 1
    GL343733.1(243530-276674)
    zebrafish
    (Danio rerio)
    Actinopterygii rgl21 ral guanine nucleotide dissociation stimulator-like more 52.96(n)
    46.69(a)
      65227  NM_001115093.2  NP_001108565.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rgl6
    Ral guanine nucleotide exchange factor
    20(a)
    1 → many
    3L(13899997-13918435)
    worm
    (Caenorhabditis elegans)
    Secernentea rgl-16
    Ral GDS-Like family member (rgl-1)
    21(a)
    1 → many
    X(3210463-3220357)


    ENSEMBL Gene Tree for RGL2 (if available)
    TreeFam Gene Tree for RGL2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RGL2 gene
    RALGPS22  RAPGEF12  RASGRF12  SOS22  RASGRF22  SOS12  RGL32  RALGDS2  
    RALGPS12  RGL12  RGL42  
    10 SIMAP similar genes for RGL2 using alignment to 9 protein entries:     RGL2_HUMAN (see all proteins):
    HKE1.5    FLJ00371    RALGDS    FLJ00185    FLJ00153    DKFZp686C2469
    RGL4    RGL3    RGL1    DKFZp781H1715

    RGL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/170 NCBI SNPs in RGL2 are shown (see all 170    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1168665241,2
    C,F,--33258950(+) CAACAT/CACCAT 8 -- us2k1 int11Minor allele frequency- C:0.02EA 120
    rs1847127391,2
    --33259130(+) ATCCCA/CGCATG 8 -- int1 us2k10--------
    rs1894287171,2
    --33259491(+) CCCCCA/CGAGTG 2 -- ut310--------
    rs18018231,2
    C,F,A,H,--33259582(-) ACATGC/TAAGGG 2 -- ut3113Minor allele frequency- T:0.03NA NS EA WA 1444
    rs1825199221,2
    --33259601(+) GGCCAA/CGAATC 2 -- ut310--------
    rs1858623251,2
    --33259619(+) GATGCA/GTTTTT 2 -- ut310--------
    rs77540651,2
    C,H,--33259626(+) TTTTCC/GAGCAC 2 -- ut314Minor allele frequency- G:0.00NS EA 420
    rs1909269401,2
    --33259659(+) AAGGTG/TGGAAG 2 -- ut310--------
    rs2006907431,2
    --33259872(+) GGGGCG/TTCCTC 2 -- ut310--------
    rs1481511951,2
    C,F,--33259903(+) ATCTTC/TCTCCC 4 R syn12Minor allele frequency- T:0.00NA EU 5793

    HapMap Linkage Disequilibrium report for RGL2 (33259431 - 33267176 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RGL2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RGL2
    DNA2.0 Custom Variant and Variant Library Synthesis for RGL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RGL2 for disorders           About GeneDecksing

    OMIM gene information: 602306    OMIM disorders: --

    7 diseases for RGL2:    About MalaCards
    normophosphatemic familial tumoral calcinosis    familial tumoral calcinosis    calcinosis    systemic lupus erythematosus
    lupus erythematosus    pancreatic cancer    pancreatitis

    Human Genome Epidemiology (HuGE) Navigator: RGL2 (2 documents)

    Export disorders for RGL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RGL2 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with RGL2)
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    1. Isolation and mapping of RAB2L, a human cDNA that encodes a protein homologous to RalGDS. (PubMed id 8976381)1, 2, 3 Isomura M.... Nakamura Y. (1996)
    2. Functional characterization of SAMD9, a protein defic ient in normophosphatemic familial tumoral calcinosis. (PubMed id 21160498)1, 2 Hershkovitz D....Sprecher E. (2011)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC. (PubMed id 9545376)1, 2 Herberg J.A.... Trowsdale J. (1998)
    6. G-protein binding features and regulation of the RalGDS family member, RGL2. (PubMed id 18540861)1, 9 Ferro E....Trabalzini L. (2008)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    9. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    10. Aberrant overexpression of the Rgl2 Ral small GTPase- specific guanine nucleotide exchange factor promotes pancreatic cancer growth t hrough Ral-dependent and Ral-independent mechanisms. (PubMed id 20801877)1 Vigil D....Der C.J. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5863 HGNC: 9769 AceView: RGL2 Ensembl:ENSG00000237441 euGenes: HUgn5863
    ECgene: RGL2 H-InvDB: RGL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RGL2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RGL2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RGL2 gene:
    Search GeneIP for patents involving RGL2

    GeneCards and IP:
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