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Aliases for RGAG1 Gene

Aliases for RGAG1 Gene

  • Retrotransposon Gag Domain Containing 1 2 3 5
  • Tumor Antigen BJ-HCC-23 3 4
  • Retrotransposon Gag Domain-Containing Protein 1 3
  • Tumor Antigen BJHCC23 3
  • KIAA1318 4
  • MART9 3
  • MAR9 3

External Ids for RGAG1 Gene

Previous GeneCards Identifiers for RGAG1 Gene

  • GC0XP109468
  • GC0XP109662
  • GC0XP099283
  • GC0XP109602

Summaries for RGAG1 Gene

GeneCards Summary for RGAG1 Gene

RGAG1 (Retrotransposon Gag Domain Containing 1) is a Protein Coding gene. Diseases associated with RGAG1 include Non-Syndromic X-Linked Intellectual Disability.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RGAG1 Gene

Genomics for RGAG1 Gene

Regulatory Elements for RGAG1 Gene

Enhancers for RGAG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF110519 0.6 ENCODE 18.7 +161.4 161354 0.8 RGAG1 TDGF1P3 AMMECR1
GH0XF110531 0.6 ENCODE 18.1 +173.4 173374 1.7 ESRRA JUN TAL1 CEBPG RARA FOSL1 NCOR1 EED ZNF207 ETV6 RGAG1 CHRDL1 TDGF1P3 LOC100131200
GH0XF110380 0.6 ENCODE 13.1 +24.0 24019 4.8 TAL1 JUN ZNF664 ZNF316 NCOR1 NR2F6 FOS MTA2 RNF2 NRF1 RGAG1 GC0XM110384
GH0XF110402 1.1 FANTOM5 Ensembl ENCODE 12.2 +44.5 44492 3.6 CTCF TBP KLF1 TAL1 JUN MAX RAD21 ZKSCAN1 GATA3 CTBP1 RGAG1 GC0XM110384 GC0XP110441
GH0XF110401 0.5 ENCODE 12.2 +42.6 42592 0.2 CTCF REST RAD21 ZKSCAN1 RGAG1 GC0XM110384 GC0XP110441
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RGAG1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RGAG1 Gene

110,358,776 bp from pter
110,456,334 bp from pter
97,559 bases
Plus strand

Genomic View for RGAG1 Gene

Genes around RGAG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RGAG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RGAG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RGAG1 Gene

Proteins for RGAG1 Gene

  • Protein details for RGAG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Retrotransposon gag domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q9P2M8

    Protein attributes for RGAG1 Gene

    1388 amino acids
    Molecular mass:
    144280 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA92556.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for RGAG1 Gene

Post-translational modifications for RGAG1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RGAG1 Gene

No data available for DME Specific Peptides for RGAG1 Gene

Domains & Families for RGAG1 Gene

Protein Domains for RGAG1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RGAG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for RGAG1 Gene

Function for RGAG1 Gene

Phenotypes for RGAG1 Gene

genes like me logo Genes that share phenotypes with RGAG1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RGAG1 Gene

Localization for RGAG1 Gene

Subcellular locations from

Jensen Localization Image for RGAG1 Gene COMPARTMENTS Subcellular localization image for RGAG1 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RGAG1 Gene

Pathways & Interactions for RGAG1 Gene

SuperPathways for RGAG1 Gene

No Data Available

Interacting Proteins for RGAG1 Gene

Gene Ontology (GO) - Biological Process for RGAG1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RGAG1 Gene

Transcripts for RGAG1 Gene

mRNA/cDNA for RGAG1 Gene

(5) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RGAG1 Gene

Retrotransposon gag domain containing 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RGAG1 Gene

No ASD Table

Relevant External Links for RGAG1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RGAG1 Gene

mRNA expression in normal human tissues for RGAG1 Gene

mRNA differential expression in normal tissues according to GTEx for RGAG1 Gene

This gene is overexpressed in Testis (x21.0) and Brain - Hypothalamus (x4.3).

Protein differential expression in normal tissues from HIPED for RGAG1 Gene

This gene is overexpressed in Brain (46.5) and Peripheral blood mononuclear cells (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RGAG1 Gene

Protein tissue co-expression partners for RGAG1 Gene

NURSA nuclear receptor signaling pathways regulating expression of RGAG1 Gene:


SOURCE GeneReport for Unigene cluster for RGAG1 Gene:

genes like me logo Genes that share expression patterns with RGAG1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RGAG1 Gene

Orthologs for RGAG1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RGAG1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RGAG1 34 35
  • 99.23 (n)
(Canis familiaris)
Mammalia RGAG1 34 35
  • 82.61 (n)
(Bos Taurus)
Mammalia RGAG1 34 35
  • 81.67 (n)
(Mus musculus)
Mammalia Rgag1 34 16 35
  • 79.76 (n)
(Rattus norvegicus)
Mammalia LOC100912526 34
  • 79.35 (n)
(Anolis carolinensis)
Reptilia RGAG1 35
  • 31 (a)
Species where no ortholog for RGAG1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RGAG1 Gene

Gene Tree for RGAG1 (if available)
Gene Tree for RGAG1 (if available)

Paralogs for RGAG1 Gene

No data available for Paralogs for RGAG1 Gene

Variants for RGAG1 Gene

Sequence variations from dbSNP and Humsavar for RGAG1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs771130284 Uncertain significance 110,453,979(+) CACAT(C/T)GCACA reference, missense
rs10126143 -- 110,362,267(+) TTAAG(C/T)TTGTT intron-variant
rs10521528 -- 110,445,924(+) TTAAT(A/G)GAACG intron-variant
rs111255886 -- 110,379,097(+) GAACA(G/T)GCTAG intron-variant
rs111274592 -- 110,445,483(+) TCAGG(A/G)CTGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RGAG1 Gene

Variant ID Type Subtype PubMed ID
esv2758884 CNV loss 17122850

Variation tolerance for RGAG1 Gene

Residual Variation Intolerance Score: 90.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.59; 56.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RGAG1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RGAG1 Gene

Disorders for RGAG1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for RGAG1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
non-syndromic x-linked intellectual disability
  • mrx
- elite association - COSMIC cancer census association via MalaCards
Search RGAG1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for RGAG1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with RGAG1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RGAG1 Gene

Publications for RGAG1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
  2. Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. (PMID: 15716091) Brandt J. … Volff J.-N. (Gene 2005) 2 3 64
  3. A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. (PMID: 16093683) Brandt J. … Volff J.-N. (Cytogenet. Genome Res. 2005) 2 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. BioID-based Identification of Skp Cullin F-box (SCF)I^-TrCP1/2 E3 Ligase Substrates. (PMID: 25900982) Coyaud E. … Raught B. (Mol. Cell Proteomics 2015) 3 64

Products for RGAG1 Gene

Sources for RGAG1 Gene

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