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RFX7 Gene

protein-coding   GIFtS: 47
GCID: GC15M056379

Regulatory Factor X, 7

(Previous name: regulatory factor X domain containing 2)
(Previous symbol: RFXDC2)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Regulatory Factor X, 71 2
RFXDC21 2 3 5
Regulatory Factor X Domain Containing 21 2
Regulatory Factor X Domain-Containing Protein 22 3
DNA-Binding Protein RFX72
Regulatory Factor X 73

External Ids:    HGNC: 257771   Entrez Gene: 648642   Ensembl: ENSG000001818277   OMIM: 6126605   UniProtKB: Q2KHR23   

Export aliases for RFX7 gene to outside databases

Previous GC identifers: GC15M054170 GC15M033206


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RFX7 Gene:
RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et
al., 2008 (PubMed 18673564)).(supplied by OMIM, Mar 2009)

GeneCards Summary for RFX7 Gene:
RFX7 (regulatory factor X, 7) is a protein-coding gene. An important paralog of this gene is RFX5.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RFX7 gene promoter:
         AML1a   GCNF   AP-4   Cdc5   LCR-F1   Tal-1beta   E47   FOXL1   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRFX7 promoter sequence
   Search Chromatin IP Primers for RFX7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RFX7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.3   Ensembl cytogenetic band:  15q21.3   HGNC cytogenetic band: 15q21.3

RFX7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RFX7 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M056379:  view genomic region     (about GC identifiers)

Start:
56,379,478 bp from pter      End:
56,535,483 bp from pter
Size:
156,006 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RFX7_HUMAN, Q2KHR2 (See protein sequence)
Recommended Name: DNA-binding protein RFX7  
Size: 1363 amino acids; 146896 Da
Sequence caution: Sequence=BAB14381.1; Type=Erroneous initiation; Sequence=BAB14988.1; Type=Erroneous initiation;
Sequence=BAC86441.1; Type=Erroneous initiation;
Secondary accessions: Q6ZRR1 Q6ZTY6 Q8N3J0 Q9H7A9 Q9H956
Alternative splicing: 2 isoforms:  Q2KHR2-1   Q2KHR2-2   

Explore the universe of human proteins at neXtProt for RFX7: NX_Q2KHR2

Explore proteomics data for RFX7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RFX7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073752.5  
    ENSEMBL proteins: 
     ENSP00000453376   ENSP00000453281   ENSP00000453611   ENSP00000387504   ENSP00000313299  
     ENSP00000397644  

    RFX7 Human Recombinant Protein Products:

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    OriGene Custom Protein Services for RFX7
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RFX7

     
    Search eBioscience for Proteins for RFX7 

     
    Search antibodies-online for proteins for RFX7 

     
    Search antibodies-online for peptides for RFX7

    RFX7 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals RFX7 Antibodies
    Abcam antibodies for RFX7
    Cloud-Clone Corp. Antibodies for RFX7
    ThermoFisher Antibodies for RFX7
    antibodies-online antibodies for RFX7 (3 products) 

    RFX7 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RFX7
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    GenScript Custom Assay Services for RFX7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RFX7
    Cloud-Clone Corp. CLIAs for RFX7
    Search eBioscience for ELISAs for RFX7 
    antibodies-online kits for RFX7 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR011991 WHTH_DNA-bd_dom
     IPR003150 DNA-bd_RFX

    Graphical View of Domain Structure for InterPro Entry Q2KHR2

    ProtoNet protein and cluster: Q2KHR2

    1 Blocks protein domain: IPB003150 DNA-binding RFX

    UniProtKB/Swiss-Prot: RFX7_HUMAN, Q2KHR2
    Similarity: Belongs to the RFX family
    Similarity: Contains 1 RFX-type winged-helix DNA-binding domain


    Find genes that share domains with RFX7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
         
    Find genes that share ontologies with RFX7           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RFX7:
     Proliferating cells 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RFX7

    miRNA
    Products:
        
    miRTarBase miRNAs that target RFX7:
    hsa-mir-26b-5p (MIRT029828), hsa-mir-320a (MIRT044661), hsa-mir-30b-5p (MIRT023454)

    Block miRNA regulation of human, mouse, rat RFX7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RFX7 (see all 83):
    hsa-miR-140-5p hsa-miR-520f hsa-miR-4272 hsa-miR-199a-3p hsa-miR-30d hsa-miR-409-5p hsa-miR-30a hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidRFX7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RFX7
    Predesigned siRNA for gene silencing in human, mouse, rat RFX7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RFX7

    Clone
    Products:
         
    OriGene clones in human, mouse for RFX7 (see all 10)
    OriGene ORF clones in mouse, rat for RFX7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RFX7 (NM_022841)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RFX7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFX7

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for RFX7
    Browse ESI BIO Cell Lines and PureStem Progenitors for RFX7 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFX7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RFX7_HUMAN, Q2KHR2: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with RFX7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RFX7
    Interactions:

        Search GeneGlobe Interaction Network for RFX7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    Selected Interacting proteins for RFX7 (Q2KHR23 ENSP000003976444) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    IGHG1P018573, ENSP000003749904I2D: score=1 STRING: ENSP00000374990
    BTAF1ENSP000002659904STRING: ENSP00000265990
    MAP3K4ENSP000003759864STRING: ENSP00000375986
    PPP4CENSP000002793874STRING: ENSP00000279387
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with RFX7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RFX7



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RFX7 gene: 
    NM_022841.5  

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000559847(uc010ugk.1 uc002adn.1) ENST00000559447 ENST00000560792
    ENST00000422057 ENST00000317318 ENST00000423270(uc010bfn.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RFX7 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RFX7 (see all 83):
    hsa-miR-140-5p hsa-miR-520f hsa-miR-4272 hsa-miR-199a-3p hsa-miR-30d hsa-miR-409-5p hsa-miR-30a hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidRFX7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RFX7
    Predesigned siRNA for gene silencing in human, mouse, rat RFX7
    Clone
    Products:
         
    OriGene clones in human, mouse for RFX7 (see all 10)
    OriGene ORF clones in mouse, rat for RFX7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RFX7 (NM_022841)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RFX7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFX7
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RFX7
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RFX7
      QuantiTect SYBR Green Assays in human, mouse, rat RFX7
      QuantiFast Probe-based Assays in human, mouse, rat RFX7

    Selected AceView cDNA sequences (see all 138):

    BM987143 AI522288 AI263290 AI424779 BQ720150 BQ929567 AA828483 AI378892 
    AI076039 AK023056 BQ185888 AA748527 AL833367 AA287248 BU680698 AA705448 
    BE350596 AA973111 AA976890 BG054753 AA029853 BF055331 BU634128 AI251923 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RFX7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCATTTAG
    RFX7 Expression
    About this image


    RFX7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Lung (Respiratory System)    fully expand to see all 2 entries
             Stem Bronchi
     
     Thymus (Hematopoietic System)
             Thymus
     
     Kidney (Urinary System)
             Metanephros
    RFX7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RFX7 Protein Expression
        Custom PCR Arrays for RFX7
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RFX7
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RFX7
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    QuantiFast Probe-based Assays in human, mouse, rat RFX7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFX7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RFX7 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rfx71 , 5 regulatory factor X, 71, 5 91.7(n)1
    92.73(a)1
      9 (40.08 cM)5
    3197581  NM_001033536.11  NP_001028708.11 
     725322405 
    chicken
    (Gallus gallus)
    Aves RFXDC21 regulatory factor X domain containing 2 78.79(n)
    80.33(a)
      431530  XM_429081.4  XP_429081.4 
    lizard
    (Anolis carolinensis)
    Reptilia RFX76
    regulatory factor X, 7
    66(a)
    1 ↔ 1
    GL344463.1(6015-12463)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.136292 Xenopus laevis transcribed sequence with moderate similarity more 77.34(n)    BJ095218.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005381791 DNA-binding protein RFX7-like 60.82(n)
    60.34(a)
      100538179  XM_003201602.2  XP_003201650.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG97276
    --
    16(a)
    1 → many
    3R(2277275-2282371)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RFX16
    Major transcriptional repressor of DNA-damage-regu...
    14(a)
    1 → many
    XII(507797-510232) YLR176C


    ENSEMBL Gene Tree for RFX7 (if available)
    TreeFam Gene Tree for RFX7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RFX7 gene
    RFX52  
    4 SIMAP similar genes for RFX7 using alignment to 6 protein entries:     RFX7_HUMAN (see all proteins):
    RFX4    RFX5    RFX2    RFX8

    Find genes that share paralogs with RFX7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RFX7 (see all 3136)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs124401421,2
    C,F,H--33360525(+) TGCAGG/AGAGGA 1 -- us2k16Minor allele frequency- A:0.18NA WA EA 364
    rs1865025851,2
    --33360622(+) GCATCA/TCACAA 1 -- us2k10--------
    rs734115251,2
    C,F--33360659(+) GTCTCT/CATTAG 1 -- us2k13Minor allele frequency- C:0.12WA CSA 122
    rs1908870331,2
    --33360709(+) CATTTG/TGCATA 1 -- us2k10--------
    rs1827665181,2
    --33360720(+) CATATC/GTTCAT 1 -- us2k10--------
    rs1888361701,2
    --33360806(+) TAAAAA/CTAGCT 1 -- us2k10--------
    rs1909205061,2
    --33360815(+) CTAATA/GTTTGT 1 -- us2k10--------
    rs717066541,2
    C--36488895(+) CTTTC-/TTTTTTT 1 -- int10--------
    rs1159795061,2
    F--56382256(+) ACTTCG/AGCCTG 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs169767341,2
    C,F,H--56382295(+) TTACAA/GATTCA 1 -- ds500120Minor allele frequency- G:0.24NA EA NS WA 2546

    HapMap Linkage Disequilibrium report for RFX7 (56379478 - 56535483 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RFX7 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676714CNV Deletion23128226
    esv2675469CNV Deletion23128226
    esv2663193CNV Deletion23128226
    esv2666678CNV Deletion23128226
    esv25623CNV Loss19812545
    nsv510401CNV Loss20534489
    nsv519725CNV Loss19592680
    nsv528965CNV Loss19592680
    nsv827341CNV Loss20364138
    nsv833018CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RFX7
    DNA2.0 Custom Variant and Variant Library Synthesis for RFX7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612660    OMIM disorders: --


    Find genes that share disorders with RFX7           About GenesLikeMe

    Genetic Association Database (GAD): RFX7

    Export disorders for RFX7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RFX7 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with RFX7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. (PubMed id 20062064)1, 4 Crowther-Swanepoel D....Houlston R.S. (Nat. Genet. 2010)
    2. Identification and characterization of novel human tissue-specific RFX transcription factors. (PubMed id 18673564)1, 2 Aftab S.... Chen N. (BMC Evol. Biol. 2008)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (Science 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64864 HGNC: 25777 AceView: FLJ12994 Ensembl:ENSG00000181827 euGenes: HUgn64864
    ECgene: RFX7 H-InvDB: RFX7

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RFX7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RFX7 gene:
    Search GeneIP for patents involving RFX7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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