Aliases for RFX2 Gene
External Ids for RFX2 Gene
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
GeneCards Summary for RFX2 Gene
RFX2 (Regulatory Factor X, 2 (Influences HLA Class II Expression)) is a Protein Coding gene. An important paralog of this gene is RFX3.