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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RFT1 Gene

protein-coding   GIFtS: 60
GCID: GC03M053122

RFT1 Homolog (S. Cerevisiae)

(Previous names: RFT1, requiring fifty three 1 homolog (S. cerevisiae))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RFT1 Homolog (S. Cerevisiae)1 2
CDG1N2 5
RFT1, Requiring Fifty Three 1 Homolog (S. Cerevisiae)1
Protein RFT1 Homolog2
Putative Endoplasmic Reticulum Multispan Transmembrane Protein2
RFT1, Requiring Fifty Three 1 Homolog2

External Ids:    HGNC: 302201   Entrez Gene: 918692   Ensembl: ENSG000001639337   OMIM: 6119085   UniProtKB: Q96AA33   

Export aliases for RFT1 gene to outside databases

Previous GC identifers: GC03U990226 GC03M052377 GC03M052980 GC03M053082 GC03M053100


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RFT1 Gene:
This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the
cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of
proteins. Mutations in this gene are associated with congenital disorder of glycosylation type In.(provided by
RefSeq, Dec 2008)

GeneCards Summary for RFT1 Gene: 
RFT1 (RFT1 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with RFT1 include congenital disorder of glycosylation, and smallpox, and among its related super-pathways are WNT ligand biogenesis and trafficking and Signaling by GPCR. GO annotations related to this gene include lipid transporter activity. An important paralog of this gene is ENSG00000272305.

UniProtKB/Swiss-Prot: RFT1_HUMAN, Q96AA3
Function: May be involved in N-linked oligosaccharide assembly. May participate in the translocation of
oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane

Gene Wiki entry for RFT1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RFT1 gene promoter:
         CREB   p53   AP-1   deltaCREB   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRFT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RFT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RFT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.1   Ensembl cytogenetic band:  3p21.1   HGNC cytogenetic band: 3p21.1

RFT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RFT1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M053122:  view genomic region     (about GC identifiers)

Start:
53,122,499 bp from pter      End:
53,164,478 bp from pter
Size:
41,980 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RFT1_HUMAN, Q96AA3 (See protein sequence)
Recommended Name: Protein RFT1 homolog  
Size: 541 amino acids; 60335 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q96J03

Explore the universe of human proteins at neXtProt for RFT1: NX_Q96AA3

Explore proteomics data for RFT1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96AA3

  • RFT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RFT1 Protein Expression
    REFSEQ proteins: NP_443091.1  
    ENSEMBL proteins: 
     ENSP00000296292   ENSP00000378223   ENSP00000420325  
    Reactome Protein details: Q96AA3
    Human Recombinant Protein Products for RFT1: 
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    Cloud-Clone Corp. Proteins for RFT1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    RFT1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007594 RFT1

    Graphical View of Domain Structure for InterPro Entry Q96AA3

    ProtoNet protein and cluster: Q96AA3

    UniProtKB/Swiss-Prot: RFT1_HUMAN, Q96AA3
    Similarity: Belongs to the RFT1 family


    RFT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RFT1_HUMAN, Q96AA3
    Function: May be involved in N-linked oligosaccharide assembly. May participate in the translocation of
    oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005319lipid transporter activity IEA--
         
    RFT1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RFT1:
     Decreased viability with TRAIL  Decreased viability with pacli  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RFT1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RFT1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RFT1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RFT1 

    miRNA
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    miRTarBase miRNAs that target RFT1:
    hsa-mir-16 (MIRT001422), hsa-mir-1 (MIRT001338)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RFT1
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate RFT1 (see all 20):
    hsa-miR-193a-3p hsa-miR-301a hsa-miR-4260 hsa-miR-28-5p hsa-miR-1827 hsa-miR-130b hsa-miR-193b hsa-miR-140-3p
    SwitchGear 3'UTR luciferase reporter plasmidRFT1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RFT1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Asparagine N-linked glycosylation
    Asparagine N-linked glycosylation0.77
    N-Glycan biosynthesis0.52
    WNT ligand biogenesis and trafficking0.77
    Post-translational protein modification0.44
    Signaling by Wnt0.62
    Metabolism of proteins0.35
    2Signaling by GPCR
    Signal Transduction0.55
    3Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein0.53

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/7        Reactome Pathways for RFT1 (see all 7)
        Signaling by Wnt
    Asparagine N-linked glycosylation
    Signal Transduction
    Metabolism of proteins
    Post-translational protein modification


    1         Kegg Pathway  (Kegg details for RFT1):
        N-Glycan biosynthesis


    RFT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RFT1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/15 Interacting proteins for RFT1 (Q96AA33 ENSP000002962924) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    GTF2BQ004033I2D: score=5 
    IDI1Q139073I2D: score=4 
    PSMA6P609003I2D: score=3 
    ACTBP607093I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006488dolichol-linked oligosaccharide biosynthetic process TAS--
    GO:0006869lipid transport ----
    GO:0008643carbohydrate transport IEA--
    GO:0018279protein N-linked glycosylation via asparagine TAS--
    GO:0043687post-translational protein modification TAS--

    RFT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RFT1

    1 HMDB Compound for RFT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Riboflavin(-)-Riboflavin (see all 30)83-88-5--

    Search CenterWatch for drugs/clinical trials and news about RFT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RFT1 gene: 
    NM_052859.3  

    Unigene Cluster for RFT1:

    RFT1 homolog (S. cerevisiae)
    Hs.631910  [show with all ESTs]
    Unigene Representative Sequence: NM_052859
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296292(uc003dgj.3) ENST00000394738 ENST00000471158 ENST00000467048

    miRNA
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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate RFT1 (see all 20):
    hsa-miR-193a-3p hsa-miR-301a hsa-miR-4260 hsa-miR-28-5p hsa-miR-1827 hsa-miR-130b hsa-miR-193b hsa-miR-140-3p
    SwitchGear 3'UTR luciferase reporter plasmidRFT1 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RFT1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFT1
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RFT1

    Additional mRNA sequence: 

    AJ318099.1 AK098811.1 AL713685.1 BC006846.1 BC043595.1 BC101247.2 BC101248.2 BC101249.2 
    BC101250.1 BC113058.1 BC113059.1 

    11 DOTS entries:

    DT.438626  DT.438922  DT.120926948  DT.100786247  DT.91739261  DT.100728536  DT.100786249  DT.120927009 
    DT.86855332  DT.95160273  DT.99982562 

    24/137 AceView cDNA sequences (see all 137):

    BF447518 CR619807 BU616987 BU528699 BC006846 BE880241 AI568579 AI284846 
    BQ642245 BI868185 BG167718 AI680333 BM826909 AA724082 AI282106 BQ924516 
    CR605993 CA430605 AA701470 CR613853 BX370310 BQ001156 BX477000 BX642407 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RFT1    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                                                                                      -                     
    SP2:                                -                                                                           
    SP3:                                                  -     -                                                   
    SP4:                                                                                                            
    SP5:                          -     -                                                                           


    ECgene alternative splicing isoforms for RFT1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RFT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGACACCTGT
    RFT1 Expression
    About this image


    See RFT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RFT1

    SOURCE GeneReport for Unigene cluster: Hs.631910
        SABiosciences Custom PCR Arrays for RFT1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFT1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RFT1 gene from 9/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rft11 , 5 RFT1 homolog (S. cerevisiae)1, 5 85.34(n)1
    87.43(a)1
      14 (18.90 cM)5
    3283701  NM_177815.31  NP_808483.21 
     306543605 
    chicken
    (Gallus gallus)
    Aves RFT11 RFT1 homolog (S. cerevisiae) 71.08(n)
    71.46(a)
      770487  NM_001142872.1  NP_001136344.1 
    lizard
    (Anolis carolinensis)
    Reptilia RFT16
    RFT1 homolog (S. cerevisiae)
    72(a)
    1 ↔ 1
    2(155568005-155596714)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5598731 protein RFT1 homolog 65.24(n)
    63.82(a)
      559873  XM_683262.4  XP_688354.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta BcDNA:GH083883
    CG31491
    CG31491 37(a)3
    48.15(n)1
    40.46(a)1
      314891  NM_132018.21  NP_572246.11 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK180.31 , 3 Protein ZK180.31 29(a)3
    43.69(n)1
    30.66(a)1
      IV(4508818-4511498)3
    1772161  NM_001028439.21  NP_001023610.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RFT1(YBL020W)4
    RFT11
    Essential integral membrane protein that is required more4
    Rft1p1
    41.84(n)1
    30.8(a)1
      2(182401-184125)4
    8522611, 4  NP_009533.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G076301 lipid transporter 44.7(n)
    36.23(a)
      830656  NM_120845.5  NP_196380.5 
    rice
    (Oryza sativa)
    Liliopsida Os07g04861001 hypothetical protein 48.48(n)
    37.94(a)
      4343254  NM_001066196.1  NP_001059661.2 


    ENSEMBL Gene Tree for RFT1 (if available)
    TreeFam Gene Tree for RFT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RFT1 gene
    ENSG000002723052  

    RFT1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/918 SNPs in RFT1 are shown (see all 918)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0625734
    Congenital disorder of glycosylation 1N (CDG1N)4--see VAR_0625732 E K mis40--------
    VAR_0443344
    Congenital disorder of glycosylation 1N (CDG1N)4--see VAR_0443342 R C mis40--------
    VAR_0625724
    Congenital disorder of glycosylation 1N (CDG1N)4--see VAR_0625722 K E mis40--------
    rs1182039131,2
    Cpathogenic153090211(-) CCTTCC/TGCAGA 2 R C mis11Minor allele frequency- T:0.00NA 4552
    rs1405526471,2
    --53054451(+) AACTAC/GGTGAA 1 -- int10--------
    rs1500527411,2
    --53054503(+) GGGGCC/TGTCCT 1 -- int10--------
    rs729653861,2
    C,F--53054637(+) GTCCCG/ACAAAC 1 -- int13Minor allele frequency- A:0.17WA CSA 122
    rs1867032351,2
    --53054646(+) ACAACA/GGGAAA 1 -- int10--------
    rs1913152211,2
    --53054655(+) AATACA/TGCTTA 1 -- int10--------
    rs25817821,2
    C,F--53054669(+) GGGGAC/TGGGGA 1 -- int16Minor allele frequency- T:0.48NA WA EA 364

    HapMap Linkage Disequilibrium report for RFT1 (53122499 - 53164478 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RFT1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834699CNV Loss17160897
    nsv460553CNV Loss19166990
    nsv822095CNV Gain20364138


    Human Gene Mutation Database (HGMD): RFT1
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611908   
    OMIM disorders: 612015  
    UniProtKB/Swiss-Prot: RFT1_HUMAN, Q96AA3
  • Congenital disorder of glycosylation 1N (CDG1N) [MIM:612015]: A multisystem disorder caused by a defect
    in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of
    glycosylation result in a wide variety of clinical features, such as defects in the nervous system development,
    psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad
    spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation,
    and maintenance of cell functions. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 3 diseases for RFT1:    About MalaCards
    congenital disorder of glycosylation    smallpox    hypotonia


    RFT1 for disorders           About GeneDecksing

    GeneTests: RFT1
    GeneReviews: RFT1
    Genetic Association Database (GAD): RFT1
    Human Genome Epidemiology (HuGE) Navigator: RFT1 (1 document)

    Export disorders for RFT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RFT1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with RFT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Human RFT1 deficiency leads to a disorder of N-linked glycosylation. (PubMed id 18313027)1, 2 Haeuptle M.A.... Hennet T. (2008)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Genome-wide meta-analysis identifies 11 new loci for a nthropometric traits and provides insights into genetic architecture. (PubMed id 23563607)1 Berndt S.I....Ingelsson E. (2013)
    5. RFT1-CDG in adult siblings with novel mutations. (PubMed id 23111317)1 Ondruskova N....Honzik T. (2012)
    6. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
    7. Large-scale genome-wide association analysis of bipol ar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 Sklar P....Purcell S.M. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    10. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91869 HGNC: 30220 AceView: RFT1 Ensembl:ENSG00000163933 euGenes: HUgn91869
    ECgene: RFT1 Kegg: 91869 H-InvDB: RFT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RFT1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RFT1 gene:
    Search GeneIP for patents involving RFT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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