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Aliases for RFPL4AL1 Gene

Aliases for RFPL4AL1 Gene

  • Ret Finger Protein Like 4A Like 1 2 3
  • Ret Finger Protein-Like 4A-Like 1 2 5

External Ids for RFPL4AL1 Gene

Previous GeneCards Identifiers for RFPL4AL1 Gene

  • GC19P056283

Summaries for RFPL4AL1 Gene

GeneCards Summary for RFPL4AL1 Gene

RFPL4AL1 (Ret Finger Protein Like 4A Like 1) is a Protein Coding gene. An important paralog of this gene is RFPL4A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RFPL4AL1 Gene

Genomics for RFPL4AL1 Gene

Regulatory Elements for RFPL4AL1 Gene

Enhancers for RFPL4AL1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RFPL4AL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RFPL4AL1 Gene

Chromosome:
19
Start:
55,769,118 bp from pter
End:
55,773,423 bp from pter
Size:
4,306 bases
Orientation:
Plus strand

Genomic View for RFPL4AL1 Gene

Genes around RFPL4AL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RFPL4AL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RFPL4AL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RFPL4AL1 Gene

Proteins for RFPL4AL1 Gene

  • Protein details for RFPL4AL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F8VTS6-RFAL1_HUMAN
    Recommended name:
    Ret finger protein-like 4A-like protein 1
    Protein Accession:
    F8VTS6

    Protein attributes for RFPL4AL1 Gene

    Size:
    287 amino acids
    Molecular mass:
    32249 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RFPL4AL1 Gene

Proteomics data for RFPL4AL1 Gene at MOPED

Post-translational modifications for RFPL4AL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RFPL4AL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RFPL4AL1 Gene

Domains & Families for RFPL4AL1 Gene

Protein Domains for RFPL4AL1 Gene

Graphical View of Domain Structure for InterPro Entry

F8VTS6

UniProtKB/Swiss-Prot:

RFAL1_HUMAN :
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 RING-type zinc finger.
Domain:
  • Contains 1 B30.2/SPRY domain.
Similarity:
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RFPL4AL1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for RFPL4AL1 Gene

Function for RFPL4AL1 Gene

Phenotypes for RFPL4AL1 Gene

GenomeRNAi human phenotypes for RFPL4AL1:
genes like me logo Genes that share phenotypes with RFPL4AL1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RFPL4AL1 Gene

Localization for RFPL4AL1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RFPL4AL1 Gene

Pathways & Interactions for RFPL4AL1 Gene

SuperPathways for RFPL4AL1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RFPL4AL1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RFPL4AL1 Gene

Drugs & Compounds for RFPL4AL1 Gene

No Compound Related Data Available

Transcripts for RFPL4AL1 Gene

mRNA/cDNA for RFPL4AL1 Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RFPL4AL1 Gene

No ASD Table

Relevant External Links for RFPL4AL1 Gene

GeneLoc Exon Structure for
RFPL4AL1
ECgene alternative splicing isoforms for
RFPL4AL1

Expression for RFPL4AL1 Gene

mRNA expression in normal human tissues for RFPL4AL1 Gene

mRNA differential expression in normal tissues according to GTEx for RFPL4AL1 Gene

This gene is overexpressed in Liver (x24.6), Testis (x12.2), and Kidney - Cortex (x5.7).
genes like me logo Genes that share expression patterns with RFPL4AL1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RFPL4AL1 Gene

Orthologs for RFPL4AL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RFPL4AL1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 29 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 28 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Rfpl4 36
  • 54 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 35 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 97 (a)
ManyToMany
-- 36
  • 97 (a)
ManyToMany
-- 36
  • 97 (a)
ManyToMany
-- 36
  • 96 (a)
ManyToMany
-- 36
  • 96 (a)
ManyToMany
chicken
(Gallus gallus)
Aves B-BTN2 36
  • 17 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 18 (a)
OneToMany
Species with no ortholog for RFPL4AL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RFPL4AL1 Gene

ENSEMBL:
Gene Tree for RFPL4AL1 (if available)
TreeFam:
Gene Tree for RFPL4AL1 (if available)

Paralogs for RFPL4AL1 Gene

Paralogs for RFPL4AL1 Gene

(11) SIMAP similar genes for RFPL4AL1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for RFPL4AL1 Gene

genes like me logo Genes that share paralogs with RFPL4AL1: view

Variants for RFPL4AL1 Gene

Sequence variations from dbSNP and Humsavar for RFPL4AL1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7258447 -- 55,769,744(+) agtgc(A/C)gtggc intron-variant
rs7258649 -- 55,769,679(+) AGGAT(A/G)GGGAT intron-variant
rs7260322 -- 55,772,298(+) ACTGT(C/G)TTCTT intron-variant
rs7507667 -- 55,768,157(+) ATGCA(A/G)TGTGC upstream-variant-2KB
rs71256167 -- 55,771,781(+) GTTCA(-/T)TTTTT intron-variant, upstream-variant-2KB

Variation tolerance for RFPL4AL1 Gene

Gene Damage Index Score: 0.59; 12.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RFPL4AL1 Gene

HapMap Linkage Disequilibrium report
RFPL4AL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RFPL4AL1 Gene

Disorders for RFPL4AL1 Gene

Relevant External Links for RFPL4AL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RFPL4AL1

No disorders were found for RFPL4AL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RFPL4AL1 Gene

Publications for RFPL4AL1 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 67

Products for RFPL4AL1 Gene

Sources for RFPL4AL1 Gene

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