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Aliases for RFPL3S Gene

Subcategory (RNA class) for RFPL3S Gene


Quality Score for this RNA gene is


Aliases for RFPL3S Gene

  • RFPL3 Antisense 2 3
  • Non-Protein Coding RNA 5 2 3
  • RFPL3 Antisense RNA 1 2 4
  • RFPL3-AS1 3 4
  • Ret Finger Protein-Like 3 Antisense Gene Protein 4
  • RFPL3 Antisense RNA 1 (Non-Protein Coding) 3
  • Ret Finger Protein-Like 3 Antisense 3
  • RFPL3 Antisense Gene Protein 1 4
  • NCRNA00005 3
  • RFPL3-AS 3
  • RFPL3ANT 3
  • RFPL3AS 3

External Ids for RFPL3S Gene

ORGUL Members for RFPL3S Gene

Previous HGNC Symbols for RFPL3S Gene

  • RFPL3-AS1

Previous GeneCards Identifiers for RFPL3S Gene

  • GC22M029451
  • GC22P029280
  • GC22M031080
  • GC22M032755
  • GC22M015717

Summaries for RFPL3S Gene

GeneCards Summary for RFPL3S Gene

RFPL3S (RFPL3 Antisense) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RFPL3S Gene

Genomics for RFPL3S Gene

Regulatory Elements for RFPL3S Gene

Genomic Location for RFPL3S Gene

32,359,906 bp from pter
32,382,052 bp from pter
22,147 bases
Minus strand

Genomic View for RFPL3S Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RFPL3S Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RFPL3S Gene

Proteins for RFPL3S Gene

  • Protein details for RFPL3S Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative protein RFPL3S
    Protein Accession:
    Secondary Accessions:
    • Q5TI83
    • Q5TI84

    Protein attributes for RFPL3S Gene

    107 amino acids
    Molecular mass:
    11739 Da
    Quaternary structure:
    No Data Available
    • The gene encoding RFPL3S is located on the opposite strand of the gene encoding RFPL3. Its transcription may play a role in RFPL3 transcription regulation
    • Sequence=CAB38257.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=CAI19584.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

neXtProt entry for RFPL3S Gene

Proteomics data for RFPL3S Gene at MOPED

Post-translational modifications for RFPL3S Gene

No Post-translational modifications

Other Protein References for RFPL3S Gene

No data available for DME Specific Peptides for RFPL3S Gene

Domains & Families for RFPL3S Gene

Protein Domains for RFPL3S Gene


Suggested Antigen Peptide Sequences for RFPL3S Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RFPL3S: view

No data available for Gene Families and UniProtKB/Swiss-Prot for RFPL3S Gene

Function for RFPL3S Gene

Molecular function for RFPL3S Gene

GENATLAS Biochemistry:
ret finger protein-like 3,antisense transcript,overlapping RFRL3

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RFPL3S

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RFPL3S Gene

Localization for RFPL3S Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RFPL3S Gene

Pathways & Interactions for RFPL3S Gene

SuperPathways for RFPL3S Gene

No Data Available

Interacting Proteins for RFPL3S Gene

Gene Ontology (GO) - Biological Process for RFPL3S Gene


No data available for Pathways by source and SIGNOR curated interactions for RFPL3S Gene

Drugs & Compounds for RFPL3S Gene

No Compound Related Data Available

Transcripts for RFPL3S Gene

Unigene Clusters for RFPL3S Gene

RFPL3 antisense:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RFPL3S

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RFPL3S Gene

No ASD Table

Relevant External Links for RFPL3S Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RFPL3S Gene

mRNA expression in normal human tissues for RFPL3S Gene

mRNA differential expression in normal tissues according to GTEx for RFPL3S Gene

This gene is overexpressed in Testis (x22.5).

Protein differential expression in normal tissues from HIPED for RFPL3S Gene

This gene is overexpressed in Heart (67.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RFPL3S Gene

SOURCE GeneReport for Unigene cluster for RFPL3S Gene Hs.274285

mRNA Expression by UniProt/SwissProt for RFPL3S Gene

Tissue specificity: Strongly expressed in the testis and weakly in brain, placenta and pancreas.
genes like me logo Genes that share expression patterns with RFPL3S: view

Protein tissue co-expression partners for RFPL3S Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for RFPL3S Gene

Orthologs for RFPL3S Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for RFPL3S Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RFPL3S 36
  • 94 (a)
Species with no ortholog for RFPL3S:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RFPL3S Gene

Gene Tree for RFPL3S (if available)
Gene Tree for RFPL3S (if available)

Paralogs for RFPL3S Gene Pseudogenes for RFPL3S Gene

genes like me logo Genes that share paralogs with RFPL3S: view

No data available for Paralogs for RFPL3S Gene

Variants for RFPL3S Gene

Sequence variations from dbSNP and Humsavar for RFPL3S Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs713620 -- 32,367,536(+) TCACC(C/T)GAAAA intron-variant
rs713647 -- 32,367,842(+) CCCCA(A/G)CATCT intron-variant
rs738267 -- 32,367,800(+) GCTCT(C/T)GGTAA intron-variant
rs3884744 -- 32,368,026(+) tacaa(A/T)tcaca intron-variant
rs5749410 -- 32,368,111(+) ATGGC(A/G)TGAAC intron-variant

Variation tolerance for RFPL3S Gene

Gene Damage Index Score: 0.92; 19.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RFPL3S Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RFPL3S Gene

Disorders for RFPL3S Gene

Relevant External Links for RFPL3S

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with RFPL3S: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RFPL3S Gene

Publications for RFPL3S Gene

  1. Duplications on human chromosome 22 reveal a novel Ret finger protein-like gene family with sense and endogenous antisense transcripts. (PMID: 10508838) Seroussi E. … Dumanski J.P. (Genome Res. 1999) 2 23 67
  2. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 67
  3. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  5. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 67

Products for RFPL3S Gene

Sources for RFPL3S Gene

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