RFFL Gene
protein-coding GIFtS: 54
GCID: GC17M033333
|
|
ring finger and FYVE-like domain containing E3 ubiquitin...(Previous name: ring finger and FYVE-like domain containing )
| |
Aliases
for RFFL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Ring Finger And FYVE-Like Domain Containing E3 Ubiquitin Protein Ligase1 2 | | Ring Finger And FYVE-Like Domain Containing1 | | RNF1891 2 3 | | CARP22 | | RNF34L1 2 3 | | FRING2 | | Caspase Regulator CARP22 3 | | RIFIFYLIN2 | | Caspases-8 And -10-Associated RING Finger Protein 22 3 | | E3 Ubiquitin-Protein Ligase Rififylin2 | | FYVE-RING Finger Protein Sakura2 3 | | Ring Finger And FYVE-Like Domain Containing 12 | | CARP-22 3 | | EC 6.3.2.-3 | | RING Finger And FYVE-Like Domain-Containing Protein 12 3 | | Fring3 | | RING Finger Protein 1892 3 | | RING Finger Protein 34-Like3 | | Fring3 | | EC 6.3.28 | | Rififylin1 | | |
| External Ids: | HGNC: 248211 | Entrez Gene: 1175842 | Ensembl: ENSG000000928717 | OMIM: 6097355 | UniProtKB: Q8WZ733 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n410546 n410547 | |
Export aliases for RFFL gene to outside databasesPrevious GC identifers: GC17M030360 GC17M029522
Summaries
for RFFL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73Function: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them forproteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates
Gene Wiki entry for RFFL
|
Genomic Views
for RFFL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010799.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RFFL gene promoter:
Max1 FOXF2 CUTL1 POU2F1 Ik-2 POU2F1a c-Myb Cart-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RFFL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RFFL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q12RFFL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M033333: view genomic region
(about GC identifiers)
Start:
|
33,333,009 bp from pter |
End:
|
33,416,338 bp from pter |
Size:
|
83,330 bases |
Orientation:
|
minus strand |
ORGUL member locations:
Legend (see complete legend)
33336130 33392336 33448541 chr17
|
Proteins
for RFFL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase rififylin Size: 363 amino acids; 40514 Da
Subunit: Binds CASP8 and CASP10
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
1 PDB 3D structure from  and Proteopedia  for RFFL:1Y02 (3D)
Secondary accessions: E1P633 Q8NHW0 Q8TBY7 Q96BE6Alternative splicing: 3 isoforms: Q8WZ73-1 Q8WZ73-2 Q8WZ73-3 Explore the universe of human proteins at neXtProt for RFFL: NX_Q8WZ73
Post-translational modifications:
Rapidly degraded after stimulation with TNFSF10, probably by caspases1
Auto-ubiquitinated (in vitro) (By similarity)1
Palmitoylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WZ73
3 DME Specific Peptides for RFFL (Q8WZ73)
RFFL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001017368.1
ENSEMBL proteins: ENSP00000326170 ENSP00000463035 ENSP00000378096 ENSP00000389832 ENSP00000412322 ENSP00000408513 ENSP00000462656 ENSP00000462499 ENSP00000395090 ENSP00000464000 ENSP00000367777 ENSP00000268850
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
RFFL for ontologies About GeneDecksing
RFFL Antibody Products:
Assay Products for RFFL: |
Protein
Domains /
Families
for RFFL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RFFL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WZ73ProtoNet protein and cluster: Q8WZ73 3 Blocks protein families: IPB000306 Zn-finger IPB001841 Zn-finger IPB003034 DNA-binding SAP
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73Similarity: Contains 1 FYVE-type zinc fingerSimilarity: Contains 1 RING-type zinc fingerSimilarity: Contains 2 SAP domains |
Function
for RFFL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73Function: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them forproteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphatesEnzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RFFL (NM_001017368) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RFFL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFFL |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFFL |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- | | GO:0016874 | ligase activity |
IEA | -- |
RFFL for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for RFFL:
Animal Models:
Mouse knock-out Rffltm1Cota for RFFL
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rffl):
RFFL for phenotypes About GeneDecksing
|
Pathways & Interactions
for RFFL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TNF receptor signaling pathway | |
1  BioSystems Pathway for RFFL
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73Pathway: Protein modification; protein ubiquitinationInteractions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RFFL
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for RFFL (Q8WZ733 ENSP000003261704) via UniProtKB, MINT, STRING, and/or I2D (see all 7) About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006886 | intracellular protein transport |
-- | -- | | GO:0006915 | apoptotic process |
IEA | -- | | GO:0016567 | protein ubiquitination |
IEA | -- |
RFFL for ontologies About GeneDecksing
|
Drugs & Compounds
for RFFL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RFFL
Search CenterWatch for drugs/clinical trials and news about RFFL
|
Transcripts
for RFFL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RFFL gene (2 alternative transcripts): NM_057178.3 NM_001017368.1 Unigene Cluster for RFFL: Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase Hs.13680 [show with all ESTs]Unigene Representative Sequence: NR_03771314 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000315249(uc010cti.1 uc002hip.2 uc002hio.2) ENST00000580569
ENST00000584655 ENST00000394597(uc002hin.1) ENST00000447669 ENST00000415395
ENST00000413582 ENST00000581039 ENST00000584541 ENST00000582308 ENST00000414419
ENST00000581265 ENST00000378516(uc002him.1) ENST00000268850(uc002hiq.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RFFL (NM_001017368) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RFFL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFFL |
Additional cDNA sequence: AF434816.1 AK093112.1 AK308689.1 AY098935.1 BC015681.2 BC028424.1 CR933651.1 NR_037713.1 NR_037714.1 13 DOTS entries: DT.40296331 DT.70100523 DT.212992 DT.95164187 DT.91672980 DT.97789427 DT.97805008 DT.100026975 DT.100789501 DT.95221368 DT.120964097 DT.91992743 DT.95336943 24/183 AceView cDNA sequences (see all 183): NM_133630 AK097811 AI033521 AB018362 BM670107 AI242571 AW296494 BX327473 BM696809 AI241579 AI369733 AW300373 BU681257 AI760772 BC002723 NM_133627 BM759246 BM739302 AA282406 BQ027317 BU786480 AI597891 BU521767 AL117459
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RFFL (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | ^ | 10 | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RFFL
|
Expression
for RFFL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RFFL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATCCTTGGT
About this image
See RFFL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RFFL
SOURCE GeneReport for Unigene cluster: Hs.13680
UniProtKB/Swiss-Prot: RFFL_HUMAN, Q8WZ73Tissue specificity: Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon andperipheral blood leukocytes
SABiosciences Custom PCR Arrays for RFFL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RFFL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RFFL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RFFL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RFFL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFFL |
Orthologs
for RFFL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RFFL gene from 4/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RFFL1 |
ring finger and FYVE-like domain containing 1 |
69.54(n)
67.78(a) |
|
417529 NM_001030711.1 NP_001025882.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
65(a) |
possible ortholog |
GL343550.1(38769-40432) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.290632 |
Transcribed sequence with strong similarity to protein more |
83.85(n) |
|
CK141680.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG170196 |
-- |
17(a) |
1 → many |
2R(8818417-8821550) |
ENSEMBL Gene Tree for RFFL (if available)
TreeFam Gene Tree for RFFL (if available) |
Paralogs
for RFFL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RFFL gene
- ENSG000002676182 RNF342
1 SIMAP similar gene for RFFL using alignment to 5 protein entries: RFFL_HUMAN (see all proteins):RNF34
RFFL for paralogs About GeneDecksing
|
Genomic Variants
for RFFL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RFFL (33333009 - 33416338 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RFFL
4 CNVs: 88429 88428 88430 88427 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RFFL |
|
Disorders
/ Diseases
for RFFL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RFFL for disorders About GeneDecksing
OMIM gene information: 609735
OMIM disorders: --
2  diseases for RFFL: About MalaCardsprostatitis carcinoma
Human Genome Epidemiology (HuGE) Navigator: RFFL (3 documents)
Export disorders for RFFL gene to outside databases
|
Publications
for RFFL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RFFL gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with RFFL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. (PubMed id 15229288)1, 3, 9 Coumailleau F....Cohen-Tannoudji M. (2004)
- Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2. (PubMed id 15576038)1, 2, 9 Tibbetts M.D....Shi Y. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. (PubMed id 15069192)1, 2 McDonald E.R. III and El-Deiry W.S. (2004)
- A microarray of ubiquitylated proteins for profiling d eubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (2012)
- Destabilization of CARP mRNAs by aloe-emodin contribu tes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. (PubMed id 21308745)1 Lin M.L....Chen S.S. (2011)
- An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1 Shimada M....Tokunaga K. (2010)
- Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1 Hosgood H.D....Lan Q. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
|
External Searches for RFFL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RFFL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RFFL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RFFL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RFFL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RFFL gene:
Search GeneIP for patents involving RFFL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RFFL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RFFL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RFFL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RFFL | | | OriGene Protein Over-expression Lysate for RFFL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RFFL | | OriGene 3'-UTR Clone for RFFL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFFL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RFFL | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RFFL | | OriGene Custom Protein Services for RFFL | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RFFL | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RFFL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RFFL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RFFL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RFFL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RFFL |
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| | | | Search Tocris compounds for RFFL |
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 | | | RFFL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFFL |
|  |  |  | | | | Search ThermoFisher Antibodies for RFFL |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFFL |
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GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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