RFC4 Gene
protein-coding GIFtS: 65
GCID: GC03M186507
|
|
replication factor C (activator 1) 4, 37kDa(Previous name: replication factor C (activator 1) 4 (37kD) )
| |
Aliases
for RFC4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Replication Factor C (Activator 1) 4, 37kDa1 2 | | A1 37 KDa Subunit2 3 | | RFC371 2 3 | | RF-C 37 KDa Subunit2 3 | | A11 2 | | Replication Factor C (Activator 1) 4 (37kD)1 | | Activator 1 37 KDa Subunit2 3 | | Replication Factor C Subunit 42 | | Activator 1 Subunit 42 3 | | RFC 37 KDa Subunit2 | | Replication Factor C 37 KDa Subunit2 3 | | |
Export aliases for RFC4 gene to outside databasesPrevious GC identifers: GC03M183282 GC03M187764 GC03M187909 GC03M187828 GC03M187990 GC03M183917 |
Summaries
for RFC4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RFC4:
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessoryproteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is aprotein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kDsubunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependentATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcriptvariants encoding the same protein have been reported. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RFC4_HUMAN, P35249Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of theaccessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in theelongation of the multiprimed DNA template
Gene Wiki entry for RFC4
|
Genomic Views
for RFC4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RFC4 gene promoter:
MEF-2A Max Sp1 aMEF-2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for RFC4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RFC4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q27 Ensembl cytogenetic band: 3q27.3 HGNC cytogenetic band: 3q27RFC4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M186507: view genomic region
(about GC identifiers)
Start:
|
186,507,669 bp from pter |
End:
|
186,524,847 bp from pter |
Size:
|
17,179 bases |
Orientation:
|
minus strand |
|
Proteins
for RFC4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RFC4_HUMAN, P35249 (See
protein sequence)Recommended Name: Replication factor C subunit 4 Size: 363 amino acids; 39682 Da
Subunit: Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex either with RFC1 or with RAD17.The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated byPCNA
Subcellular location: Nucleus (Probable)
Miscellaneous: Despite of the presence of a putative ATP-binding motif, this protein does not bind ATP
Secondary accessions: D3DNV2 Q6FHX7Explore the universe of human proteins at neXtProt for RFC4: NX_P35249
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P35249
RFC4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_002907.1 NP_853551.1
ENSEMBL proteins: ENSP00000399769 ENSP00000296273 ENSP00000401429 ENSP00000411300 ENSP00000394870 ENSP00000413065 ENSP00000407982 ENSP00000415099 ENSP00000399314 ENSP00000376272 Reactome Protein details: P35249
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RFC4 for ontologies About GeneDecksing
RFC4 Antibody Products:
Assay Products for RFC4: |
Protein
Domains /
Families
for RFC4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RFC4 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P35249ProtoNet protein and cluster: P35249 1 Blocks protein family: IPB013748 Replication factor C
UniProtKB/Swiss-Prot: RFC4_HUMAN, P35249Similarity: Belongs to the activator 1 small subunits family |
Function
for RFC4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RFC4_HUMAN, P35249Function: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of theaccessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in theelongation of the multiprimed DNA template Genatlas biochemistry entry for RFC4:replication factor C4,component of complex A-1,DNA polymerase accessory protein "clamp loader",ATP dependent,requiredto assemble PCNA and polymerase delta on the DNA template
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RFC4 (NM_002916) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RFC4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFC4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFC4 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RFC4 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RFC4:
|
Pathways & Interactions
for RFC4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lagging Strand Synthesis | | | 2 | Ubiquitinated Orc1 is degraded by the proteasome | | | 3 | Global Genomic NER (GG-NER) | | | 4 | Nucleotide Excision Repair | | | 5 | Activation of ATR in response to replication stress | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for RFC4
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RFC4
1  GeneGo (Thomson Reuters) Pathway for RFC4
1  BioSystems Pathway for RFC4
5/25 
Reactome Pathways for RFC4 (see all 25)
3 
Kegg Pathways (Kegg details for RFC4):
RFC4 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RFC4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/830 Interacting proteins for RFC4 (P352491, 2, 3 ENSP000002962734) via UniProtKB, MINT, STRING, and/or I2D (see all 830)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
RFC4 for ontologies About GeneDecksing
|
Drugs & Compounds
for RFC4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RFC4 for compounds About GeneDecksing
 Browse Tocris compounds for RFC4
1 Novoseek chemical compound relationship for RFC4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| atp |
37.1 |
2 |
1670772 (2) |
Search CenterWatch for drugs/clinical trials and news about RFC4
|
Transcripts
for RFC4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RFC4 gene (2 alternative transcripts): NM_002916.3 NM_181573.2 Unigene Cluster for RFC4: Replication factor C (activator 1) 4, 37kDa Hs.732098 [show with all ESTs]Unigene Representative Sequence: NM_18157314 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000433496 ENST00000479307 ENST00000296273(uc003fqz.3) ENST00000417876
ENST00000494047(uc011bsd.2) ENST00000460408 ENST00000418288 ENST00000449502
ENST00000447345 ENST00000489028 ENST00000427785 ENST00000448497 ENST00000411792
ENST00000392481(uc011bsc.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RFC4 (NM_002916) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RFC4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFC4 |
Additional cDNA sequence: AK297282.1 BC017452.1 BC024022.1 BT006987.1 CR536561.1 24/30 DOTS entries (see all 30): DT.87016306 DT.100868317 DT.95352196 DT.214260 DT.95378443 DT.100650807 DT.100059274 DT.100718855 DT.92054629 DT.87000025 DT.120915857 DT.92471144 DT.100704108 DT.100704106 DT.120915952 DT.120915728 DT.91855254 DT.95366981 DT.95367045 DT.40111645 DT.92471199 DT.100704120 DT.100848057 DT.121345669 24/300 AceView cDNA sequences (see all 300): CR608475 BE695818 AA354089 BC024022 CR616552 F08084 CR625223 NM_181573 BM800308 CA773606 AW327326 BG498617 BU169798 AI189808 BM472875 AI200322 AA704058 AL042687 AL526272 BP338080 CR536561 AU132734 BQ441143 AL525156
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for RFC4 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RFC4
|
Expression
for RFC4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RFC4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTGGTTGT
About this image
See RFC4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RFC4
SOURCE GeneReport for Unigene cluster: Hs.732098
SABiosciences Custom PCR Arrays for RFC4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RFC4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RFC4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RFC4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RFC4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFC4 |
Orthologs
for RFC4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RFC4 gene from 9/41 species (see all 41) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RFC41 |
replication factor C (activator 1) 4, 37kDa |
76(n)
84.31(a) |
|
424958 NM_001006550.1 NP_001006550.1 |
lizard
(Anolis carolinensis) |
Reptilia |
RFC46 |
-- |
82(a) |
1 ↔ 1 |
GL343321.1(83410-110295) |
African clawed frog
(Xenopus laevis) |
Amphibia |
RFC22 |
replication factor C p37 subunit |
76.64(n) |
|
AB080268.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb82e022 |
Danio rerio cDNA clone MGC64030 IMAGE6793333, complete more |
75.06(n) |
|
BC054598.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG81421 , 3 |
DNA replication DNA binding3
CG81421 |
54(a)3
53.03(n)1
55.62(a)1 |
|
16E13
327631 NM_133017.31 NP_573245.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
rfc-43 |
Replication factor C |
43(a) |
|
III(7043840-7045403) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
RFC2(YJR068W)4
RFC21 |
Subunit of heteropentameric Replication factor C (RF-C), more4
Rfc2p1 |
55.17(n)1
53.92(a)1 |
|
10(567643-568704)4
8535311, 4 NP_012602.31 NP_012602.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
EMB19681 |
replication factor C subunit 2/4 |
57.56(n)
57.14(a) |
|
838771 NM_102018.3 NP_564148.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.2762 |
Oryza sativa (japonica cultivar-group) OsRFC2 mRNA more |
70.85(n) |
|
AB045677.1 |
ENSEMBL Gene Tree for RFC4 (if available)
TreeFam Gene Tree for RFC4 (if available) |
Paralogs
for RFC4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for RFC4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RFC4 (186507669 - 186524847 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RFC4
3 CNVs: 47856 3467 32540
1 Indel: 27248 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RFC4 |
|
Disorders
/ Diseases
for RFC4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RFC4 for disorders About GeneDecksing
OMIM gene information: 102577
OMIM disorders: --
7  diseases for RFC4: About MalaCardsgraft versus host disease multiple sclerosis hepatocellular carcinoma immunodeficiency
carcinoma malaria prostatitis
Human Genome Epidemiology (HuGE) Navigator: RFC4 (7 documents)
Export disorders for RFC4 gene to outside databases
|
Publications
for RFC4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RFC4 gene, integrated from 9 sources (see all 70):
(articles sorted by number of sources associating them with RFC4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Purification and characterization of human DNA damage checkpoint Rad complexes. (PubMed id 11572977)1, 2 Lindsey-Boltz L.A.... Sancar A. (2001)
- Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23. (PubMed id 7774928)1, 3 Okumura K....Ozawa K. (1995)
- Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells. (PubMed id 1351677)1, 2 Chen M.... Hurwitz J. (1992)
- The human EKC/KEOPS complex is recruited to Cullin2 ub iquitin ligases by the human tumour antigen PRAME. (PubMed id 22912744)1 Costessi A....Stunnenberg H.G. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Genetic associations for activated partial thromboplas tin time and prothrombin time, their gene expression profiles, and risk of coron ary artery disease. (PubMed id 22703881)1 Tang W....Folsom A.R. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
|
External Searches for RFC4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RFC4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RFC4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RFC4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RFC4 gene:
Search GeneIP for patents involving RFC4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RFC4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for RFC4 | | OriGene shRNA RFP for RFC4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RFC4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RFC4 | | | OriGene Protein Over-expression Lysate for RFC4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RFC4 | | OriGene 3'-UTR Clone for RFC4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RFC4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RFC4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RFC4 | | OriGene Custom Protein Services for RFC4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RFC4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RFC4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RFC4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RFC4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RFC4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RFC4 |
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| | | | Search Tocris compounds for RFC4 |
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 | | | RFC4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RFC4 |
|  |  |  | | | | ThermoFisher Antibody for RFC4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RFC4 |
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