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Aliases for REXO1L1P Gene

Aliases for REXO1L1P Gene

  • REX1, RNA Exonuclease 1 Homolog (S. Cerevisiae)-Like 1, Pseudogene 2 3
  • Antigen GOR Homolog 3 4
  • REXO1L1 3 4
  • GOR 3 4
  • REX1, RNA Exonuclease 1 Homolog (S. Cerevisiae)-Like 1 2
  • REX1, RNA Exonuclease 1 Homolog-Like 1 3
  • RNA Exonuclease 1 Homolog-Like 1 4
  • Exonuclease GOR 3
  • EC 3.1.-.- 4

External Ids for REXO1L1P Gene

Previous Symbols for REXO1L1P Gene

  • REXO1L1

Summaries for REXO1L1P Gene

GeneCards Summary for REXO1L1P Gene

REXO1L1P (REX1, RNA Exonuclease 1 Homolog (S. Cerevisiae)-Like 1, Pseudogene) is a Pseudogene. Diseases associated with REXO1L1P include hepatitis d. Among its related pathways are Ribosome biogenesis in eukaryotes. An important paralog of this gene is REXO1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for REXO1L1P Gene

Genomics for REXO1L1P Gene

Genomic Location for REXO1L1P Gene

Start:
85,656,304 bp from pter
End:
85,663,497 bp from pter
Size:
7,194 bases
Orientation:
Minus strand

Genomic View for REXO1L1P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for REXO1L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for REXO1L1P Gene

No data available for Regulatory Elements for REXO1L1P Gene

Proteins for REXO1L1P Gene

  • Protein details for REXO1L1P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IX06-GOR_HUMAN
    Recommended name:
    Putative exonuclease GOR
    Protein Accession:
    Q8IX06
    Secondary Accessions:
    • A6NK34
    • O95107

    Protein attributes for REXO1L1P Gene

    Size:
    675 amino acids
    Molecular mass:
    73855 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAN77012.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305};

neXtProt entry for REXO1L1P Gene

Proteomics data for REXO1L1P Gene at MOPED

Post-translational modifications for REXO1L1P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for REXO1L1P Gene

Domains for REXO1L1P Gene

UniProtKB/Swiss-Prot:

GOR_HUMAN
Domain:
  • Contains 1 exonuclease domain.:
    • Q8IX06
Family:
  • Belongs to the REXO1/REXO3 family.:
    • Q8IX06
genes like me logo Genes that share domains with REXO1L1P: view

No data available for Gene Families for REXO1L1P Gene

Function for REXO1L1P Gene

Enzyme Numbers (IUBMB) for REXO1L1P Gene

Gene Ontology (GO) - Molecular Function for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0004527 exonuclease activity IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with REXO1L1P: view

No data available for Molecular function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for REXO1L1P Gene

Localization for REXO1L1P Gene

Subcellular locations from UniProtKB/Swiss-Prot for REXO1L1P Gene

Cytoplasm. Nucleus.

Gene Ontology (GO) - Cellular Components for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with REXO1L1P: view

Pathways for REXO1L1P Gene

genes like me logo Genes that share pathways with REXO1L1P: view

Pathways by source for REXO1L1P Gene

1 KEGG pathway for REXO1L1P Gene

Interacting Proteins for REXO1L1P Gene

Gene Ontology (GO) - Biological Process for REXO1L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0090305 nucleic acid phosphodiester bond hydrolysis IEA --
genes like me logo Genes that share ontologies with REXO1L1P: view

Transcripts for REXO1L1P Gene

mRNA/cDNA for REXO1L1P Gene

(1) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for REXO1L1P Gene

No ASD Table

Relevant External Links for REXO1L1P Gene

GeneLoc Exon Structure for
REXO1L1P
ECgene alternative splicing isoforms for
REXO1L1P

Expression for REXO1L1P Gene

mRNA expression in normal human tissues for REXO1L1P Gene

mRNA differential expression in normal tissues according to GTEx for REXO1L1P Gene

This gene is overexpressed in Brain - Cortex (12.3).
genes like me logo Genes that share expressions with REXO1L1P: view

Orthologs for REXO1L1P Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for REXO1L1P Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 24 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 65 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 25 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii rexo1 37
  • 22 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG12877 37
  • 18 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y56A3A.33 37
  • 31 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RNH70 37
  • 18 (a)
OneToMany
Species with no ortholog for REXO1L1P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for REXO1L1P Gene

ENSEMBL:
Gene Tree for REXO1L1P (if available)
TreeFam:
Gene Tree for REXO1L1P (if available)

Paralogs for REXO1L1P Gene

Paralogs for REXO1L1P Gene

genes like me logo Genes that share paralogs with REXO1L1P: view

Variants for REXO1L1P Gene

Sequence variations from dbSNP and Humsavar for REXO1L1P Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1992083 -- 85,659,450(-) AACAG(A/G)CAAAA nc-transcript-variant
rs2575410 -- 85,660,133(-) GATTT(A/G)CGGTT nc-transcript-variant
rs3930368 -- 85,656,941(-) CCTGC(A/C)GGGAC nc-transcript-variant
rs4091480 -- 85,657,449(-) ATGAT(G/T)TCTTC nc-transcript-variant
rs4739712 -- 85,659,856(+) GCAGG(C/T)ATTTA nc-transcript-variant

Relevant External Links for REXO1L1P Gene

HapMap Linkage Disequilibrium report
REXO1L1P

No data available for Structural Variations from Database of Genomic Variants (DGV) for REXO1L1P Gene

Disorders for REXO1L1P Gene

(1) MalaCards Diseases for REXO1L1P Gene

Search for REXO1L1P Gene in MalaCards »
genes like me logo Genes that share disorders with REXO1L1P: view

No data available for UniProtKB/Swiss-Prot for REXO1L1P Gene

Publications for REXO1L1P Gene

  1. The GOR gene product cannot cross-react with hepatitis C virus in humans. (PMID: 11472404) Koike R. … Miyasaka N. (Clin. Exp. Immunol. 2001) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Serum immunoglobulin G antibodies to the GOR autoepitope are present in patients with occult hepatitis C virus (HCV) infection despite lack of HCV-specific antibodies. (PMID: 17699833) Quiroga J.A. … CarreA+o V. (Clin. Vaccine Immunol. 2007) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4

Products for REXO1L1P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate REXO1L1P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for REXO1L1P
    • Block miRNA regulation of REXO1L1P using miScript Target Protectors

    Sources for REXO1L1P Gene

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