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RETNLB Gene

protein-coding   GIFtS: 55
GCID: GC03M108462

Resistin Like Beta

  See RETNLB-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Resistin Like Beta1 2     RELM-beta2
Colon And Small Intestine-Specific Cysteine-Rich Protein2 3     RELMb2
Colon Carcinoma-Related Gene Protein2 3     XCP22
Cysteine-Rich Secreted Protein A12-Alpha-Like 12 3     C/EBP-Epsilon Regulated Myeloid-Specific Secreted Cysteine-Rich Protein
Precursor 22
Cysteine-Rich Secreted Protein FIZZ22 3     Cysteine-Rich Secreted A12-Alpha-Like Protein 12
FIZZ22 3     Found In Inflammatory Zone 12
HXCP22 3     Resistin-Like Beta2
RELMbeta2 3     CCRG3
FIZZ12     RETNL23

External Ids:    HGNC: 203881   Entrez Gene: 846662   Ensembl: ENSG000001635157   OMIM: 6056455   UniProtKB: Q9BQ083   

Export aliases for RETNLB gene to outside databases

Previous GC identifers: GC03M108001 GC03M109755 GC03M109794 GC03M109956 GC03M105848


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RETNLB Gene:
RETNLB (resistin like beta) is a protein-coding gene. Diseases associated with RETNLB include insulin resistance. GO annotations related to this gene include hormone activity. An important paralog of this gene is RETN.

UniProtKB/Swiss-Prot: RETNB_HUMAN, Q9BQ08
Function: Probable hormone

Gene Wiki entry for RETNLB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the RETNLB gene promoter:
         Sox5   p53   MyoD   Tal-1beta   E47   Meis-1b   C/EBPalpha   RORalpha1   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRETNLB promoter sequence
   Search Chromatin IP Primers for RETNLB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RETNLB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.1   Ensembl cytogenetic band:  3q13.13   HGNC cytogenetic band: 3q13.1

RETNLB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RETNLB gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M108462:  view genomic region     (about GC identifiers)

Start:
108,462,271 bp from pter      End:
108,476,231 bp from pter
Size:
13,961 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RETNB_HUMAN, Q9BQ08 (See protein sequence)
Recommended Name: Resistin-like beta precursor  
Size: 111 amino acids; 11730 Da
Subunit: Homodimer; disulfide-linked (By similarity)
Secondary accessions: Q14D27

Explore the universe of human proteins at neXtProt for RETNLB: NX_Q9BQ08

REFSEQ proteins: NP_115968.1  
ENSEMBL proteins: 
 ENSP00000295755  

RETNLB Human Recombinant Protein Products:

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ThermoFisher Antibodies for RETNLB
LSBio Antibodies in human, mouse, rat for RETNLB

RETNLB Assay Products:

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Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.
Search eBioscience for ELISAs for RETNLB 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR009714 Resistin

Graphical View of Domain Structure for InterPro Entry Q9BQ08

ProtoNet protein and cluster: Q9BQ08

1 Blocks protein domain: IPB009714 Resistin

UniProtKB/Swiss-Prot: RETNB_HUMAN, Q9BQ08
Similarity: Belongs to the resistin/FIZZ family


Find genes that share domains with RETNLB           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: RETNB_HUMAN, Q9BQ08
Function: Probable hormone

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
GO:0005179hormone activity IEA--
     
Find genes that share ontologies with RETNLB           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for RETNLB:
 Synthetic lethal with Ras 

     5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Retnlb):
 digestive/alimentary  hematopoietic system  homeostasis/metabolism  immune system  mortality/aging 

Find genes that share phenotypes with RETNLB           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Retnlbtm1Gdw for RETNLB

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RETNLB
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RETNLB

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RETNLB
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RETNLB

miRNA
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Block miRNA regulation of human, mouse, rat RETNLB using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate RETNLB:
hsa-miR-511 hsa-miR-556-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for RETNLB
Predesigned siRNA for gene silencing in human, mouse, rat RETNLB

Gene Editing
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DNA2.0 Custom Protein Engineering Service for RETNLB

Clone
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OriGene clones in human, mouse for RETNLB (see all 6)
OriGene ORF clones in mouse, rat for RETNLB
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RETNLB (NM_032579)
Sino Biological Human cDNA Clone for RETNLB
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RETNLB
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RETNLB

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RETNLB


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
RETNB_HUMAN, Q9BQ08: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005576extracellular region IEA--

Find genes that share ontologies with RETNLB           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for RETNLB About    
See pathways by source

SuperPathContained pathways About
1Selected targets of C EBPbeta
Selected targets of C EBPbeta
2IL4-mediated signaling events
IL4-mediated signaling events


1 BioSystems Pathway for RETNLB
    IL4-mediated signaling events



    Pathway & Disease-focused RT2 Profiler PCR Array including RETNLB: 
          Allergy & Asthma in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for RETNLB

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for RETNLB (ENSP000002957554) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
STAT6ENSP000003001344STRING: ENSP00000300134
SIRT5ENSP000003685524STRING: ENSP00000368552
HDAC6ENSP000003340614STRING: ENSP00000334061
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008283cell proliferation NAS11209052

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for RETNLB (RETNB)

1 Novoseek inferred chemical compound relationship for RETNLB gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cysteine 15.4 1 11358969 (1)



Find genes that share compounds with RETNLB           About GenesLikeMe



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for RETNLB gene: 
NM_032579.2  

Unigene Cluster for RETNLB:

Resistin like beta
Hs.307047  [show with all ESTs]
Unigene Representative Sequence: AF323084
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000482939 ENST00000295755(uc003dxh.2)
miRNA
Products:
     
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2 qRT-PCR Assays for microRNAs that regulate RETNLB:
hsa-miR-511 hsa-miR-556-3p
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for RETNLB
Predesigned siRNA for gene silencing in human, mouse, rat RETNLB
Clone
Products:
     
OriGene clones in human, mouse for RETNLB (see all 6)
OriGene ORF clones in mouse, rat for RETNLB
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RETNLB (NM_032579)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RETNLB
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RETNLB
Primer
Products:
    
OriGene qPCR primer pairs and template standards for RETNLB
OriGene qSTAR qPCR primer pairs in human, mouse for RETNLB
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RETNLB
  QuantiTect SYBR Green Assays in human, mouse, rat RETNLB
  QuantiFast Probe-based Assays in human, mouse, rat RETNLB

Additional mRNA sequence: 

AF290873.1 AF323084.1 AM050721.1 AY358655.1 BC069318.1 BC113502.1 BC113528.1 

1 DOTS entry:

DT.406430 

14 AceView cDNA sequences:

BC069318 AA570296 BX097733 NM_032579 AY358655 AF323084 AA515389 AI732336 
BX957161 AA524300 BX643160 AF290873 AF323921 AI732383 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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RETNLB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACAGTAATGA
RETNLB Expression
About this image


RETNLB expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Brain (Nervous System)    fully expand to see all 4 entries
         Cerebral Cortex
 
 Ovary (Reproductive System)
         Oviduct
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Liver (Hepatobiliary System)
         Hepatocytes Liver Lobule
 
 Colon (Gastrointestinal Tract)
RETNLB Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

SOURCE GeneReport for Unigene cluster: Hs.307047

UniProtKB/Swiss-Prot: RETNB_HUMAN, Q9BQ08
Tissue specificity: Expressed only in the gastrointestinal tract, particularly the colon

    Pathway & Disease-focused RT2 Profiler PCR Array including RETNLB: 
          Allergy & Asthma in human mouse rat

Primer
Products:
OriGene qPCR primer pairs and template standards for RETNLB
OriGene qSTAR qPCR primer pairs in human, mouse for RETNLB
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RETNLB
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QuantiFast Probe-based Assays in human, mouse, rat RETNLB
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RETNLB

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for RETNLB gene from Selected species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Retnlb1 , 5 resistin like beta1, 5 73.4(n)1
60.58(a)1
  16 (30.75 cM)5
572631  NM_023881.41  NP_076370.31 
 488168565 
lizard
(Anolis carolinensis)
Reptilia --
--
Uncharacterized protein
39(a)
38(a)
many ↔ many
many ↔ many
2(102944753-102953351)
2(102964086-102969981)


ENSEMBL Gene Tree for RETNLB (if available)
TreeFam Gene Tree for RETNLB (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for RETNLB gene
RETN2  
2 SIMAP similar genes for RETNLB using alignment to 1 protein entry:     RETNB_HUMAN:
RELM-beta    RETN

Find genes that share paralogs with RETNLB           About GenesLikeMe


1 Pseudogenes.org Pseudogene for RETNLB
PGOHUM00000237713


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for RETNLB (see all 149)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs98332391,2
C,F,H--108445682(+) TACATG/CATGGG 1 -- us2k17Minor allele frequency- C:0.11NS EA WA NA 660
rs2017242881,2
C--108474002(+) ACTATC/TGCAAG 1 -- int10--------
rs98400921,2
C--108474098(+) actctA/Ggggac 1 -- int10--------
rs76273101,2
C,H--108474122(+) ggggaG/Tggggg 1 -- int11Minor allele frequency- T:0.00NA 2
rs76273171,2
C--108474138(+) tagcaT/Ctggga 1 -- int11Minor allele frequency- C:0.00NA 2
rs76159121,2
C,A--108474275(+) aaaATA/GAaaaa 1 -- int10--------
rs130946561,2
C--108474284(+) AAAAAA/GAAAAA 1 -- int10--------
rs117163331,2
C,H--108474292(+) AAAAAA/TAAATA 1 -- int11Minor allele frequency- T:0.00NA 2
rs1408218921,2
--108474292(+) AAAAA-/TAAATA 1 -- int10--------
rs1496535231,2
--108474310(+) AAATAA/TAAATG 1 -- int10--------

HapMap Linkage Disequilibrium report for RETNLB (108462271 - 108476231 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for RETNLB:    About this table    
Variant IDTypeSubtypePubMed ID
esv2670614CNV Deletion23128226
nsv829659CNV Gain17160897
nsv522119CNV Gain19592680
nsv829661CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing RETNLB
DNA2.0 Custom Variant and Variant Library Synthesis for RETNLB

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 605645    OMIM disorders: --

1 disease for RETNLB:    
About MalaCards
insulin resistance

1 disease from the University of Copenhagen DISEASES database for RETNLB:
Pulmonary fibrosis

Find genes that share disorders with RETNLB           About GenesLikeMe

2 Novoseek inferred disease relationships for RETNLB gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
insulin resistance 48.9 2 16815164 (1), 12531878 (1)
barrett esophagus 48.5 1 19967544 (1)

Genetic Association Database (GAD): RETNLB

Export disorders for RETNLB gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for RETNLB gene, integrated from 10 sources (see all 33):
(articles sorted by number of sources associating them with RETNLB)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Bioinformatics based discovery of a novel factor with apparent specificity to colon cancer. (PubMed id 12224133)1, 2, 9 De Young M.P.... Narayanan R. (In Vivo 2002)
  2. A family of tissue-specific resistin-like molecules. (PubMed id 11209052)1, 2, 9 Steppan C.M.... Lazar M.A. (Proc. Natl. Acad. Sci. U.S.A. 2001)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism. (PubMed id 12574343)1, 3 StA1tz A.M....WoisetschlAoger M. (J. Immunol. 2003)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  6. Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice. (PubMed id 11090083)1, 2 Kubota T.... Koeffler H.P. (Blood 2000)
  7. FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. (PubMed id 10921885)1, 3 Holcomb I.N.... Hebert C.C. (EMBO J. 2000)
  8. Expression of resistin-like molecule beta in gastric cancer: its relationship with clinicopathological parameters and prognosis. (PubMed id 19967544)1, 9 Zheng L....Tong Q. (Virchows Arch. 2010)
  9. Enhanced expression of resistin-like molecule beta in human colon cancer and its clinical significance. (PubMed id 18594973)1, 9 Zheng L.D....Hou X.H. (Dig. Dis. Sci. 2009)
  10. Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia. (PubMed id 16427636)1, 9 Renigunta A....Haenze J. (FEBS Lett. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84666 HGNC: 20388 AceView: RETNLB Ensembl:ENSG00000163515 euGenes: HUgn84666
ECgene: RETNLB H-InvDB: RETNLB

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for RETNLB Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for RETNLB gene:
Search GeneIP for patents involving RETNLB

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
 Antibodies for RETNLB (RELM beta)   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
 Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for RETNLB   OriGene RNAi products in human, mouse, rat for RETNLB  
 OriGene qPCR primer pairs and template standards for RETNLB   OriGene Protein Over-expression Lysate for RETNLB  
 OriGene MassSpec something-or-other for RETNLB   OriGene clones in human, mouse for RETNLB  
 OriGene qSTAR qPCR primer pairs in human, mouse for RETNLB   OriGene Purified Protein for RETNLB  
 OriGene ORF clones in mouse, rat for RETNLB   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for RETNLB   OriGene Custom Protein Services for RETNLB  

 
 
 Block miRNA regulation of human, mouse, rat RETNLB using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RETNLB
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RETNLB Predesigned siRNA for gene silencing in human, mouse, rat RETNLB
 QuantiFast Probe-based Assays in human, mouse, rat RETNLB QuantiTect SYBR Green Assays in human, mouse, rat RETNLB
 PCR Arrays including human, mouse, rat RETNLB Search Chromatin IP Primers for RETNLB
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RETNLB  Search GeneGlobe Interaction Network for RETNLB
 Regulatory tfbs in RETNLB promoter
 GenScript Custom Purified and Recombinant Proteins Services for RETNLB GenScript cDNA clones with any tag delivered in your preferred vector for RETNLB
 GenScript Custom Assay Services for RETNLB GenScript Custom overexpressing Cell Line Services for RETNLB
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for RETNLB (RETNB)
 Browse Sino Biological Proteins
 Browse Sino Biological Cell Lysates
 cDNA Clones for RETNLB
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Proteins for RETNLB
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 RETNLB antibodies
 RETNLB proteins
 RETNLB lysates
 Antibodies for RETNLB
 See all of Abcam's Antibodies, Kits and Proteins for RETNLB
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Recombinant Protein for RETNLB
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for RETNLB
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RETNLB
 Browse SwitchGear 3'UTR luciferase reporter plasmids for RETNLB
 SwitchGear Promoter luciferase reporter plasmids for RETNLB
 ThermoFisher Antibodies for RETNLB
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RETNLB
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RETNLB
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RETNLB
 LSBio Antibodies in human, mouse, rat for RETNLB
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for RETNLB
  Search eBioscience for proteins for RETNLB
  Search eBioscience for elisas for RETNLB
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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