External Ids for RERG Gene
Previous GeneCards Identifiers for RERG Gene
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
GeneCards Summary for RERG Gene
RERG (RAS-Like, Estrogen-Regulated, Growth Inhibitor) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RASL12.
UniProtKB/Swiss-Prot for RERG Gene
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.