Aliases for REPS2 Gene
External Ids for REPS2 Gene
Previous GeneCards Identifiers for REPS2 Gene
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for REPS2 Gene
REPS2 (RALBP1 Associated Eps Domain Containing 2) is a Protein Coding gene. Diseases associated with REPS2 include Prostate Cancer. Among its related pathways are Cytoskeleton remodeling_RalA regulation pathway and Cytoskeleton remodeling_RalB regulation pathway. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is REPS1.
UniProtKB/Swiss-Prot for REPS2 Gene
Involved in growth factor signaling through its influence on the Ral signaling pathway.