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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RENBP Gene

protein-coding   GIFtS: 63
GCID: GC0XM153200

Renin Binding Protein

(Previous name: renin-binding protein)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Renin Binding Protein1 2     AGE2 3
GlcNAc 2-Epimerase1 2 3     EC 5.1.3.83 8
N-Acetyl-D-Glucosamine 2-Epimerase1 2 3     RBP2
Renin-Binding Protein1 3     RNBP2
N-Acylglucosamine 2-Epimerase1 2     RnBP3

External Ids:    HGNC: 99591   Entrez Gene: 59732   Ensembl: ENSG000001020327   OMIM: 3124205   UniProtKB: P516063   

Export aliases for RENBP gene to outside databases

Previous GC identifers: GC0XM147338 GC0XM149655 GC0XM150786 GC0XM151668 GC0XM152721 GC0XM152853 GC0XM141853


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RENBP Gene:
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight
renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin.
The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that
it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the
literature. (provided by RefSeq, Jul 2008)

GeneCards Summary for RENBP Gene: 
RENBP (renin binding protein) is a protein-coding gene. Diseases associated with RENBP include sialuria, and wilms tumor. GO annotations related to this gene include mannose-6-phosphate isomerase activity and protein homodimerization activity.

UniProtKB/Swiss-Prot: RENBP_HUMAN, P51606
Function: Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a
protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the
N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of
Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded

Gene Wiki entry for RENBP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RENBP gene promoter:
         AhR   SRY   Elk-1   Sp1   CUTL1   Tal-1beta   ITF-2   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRENBP promoter sequence
   Search SABiosciences Chromatin IP Primers for RENBP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RENBP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

RENBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RENBP gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM153200:  view genomic region     (about GC identifiers)

Start:
153,200,716 bp from pter      End:
153,210,232 bp from pter
Size:
9,517 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RENBP_HUMAN, P51606 (See protein sequence)
Recommended Name: N-acylglucosamine 2-epimerase  
Size: 427 amino acids; 48831 Da
Subunit: Homodimer
Caution: It is uncertain whether Met-1 or Met-11 is the initiator
Sequence caution: Sequence=AAH15558.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA01082.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA01082.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence;
Secondary accessions: B4DNZ3 Q96BI6
Alternative splicing: 2 isoforms:  P51606-1   P51606-2   

Explore the universe of human proteins at neXtProt for RENBP: NX_P51606

Explore proteomics data for RENBP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P51606

  • 3 DME Specific Peptides for RENBP (P51606)
     YAELGDWC  MAVPMMLL  EAMIAFLMGY 

    RENBP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RENBP Protein Expression
    REFSEQ proteins: NP_002901.2  
    ENSEMBL proteins: 
     ENSP00000377303   ENSP00000405759   ENSP00000359014   ENSP00000394220   ENSP00000409034  
     ENSP00000399278   ENSP00000387811  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR012341 6hp_glycosidase
     IPR010819 AGE/RnBP
     IPR008928 6-hairpin_glycosidase-like

    Graphical View of Domain Structure for InterPro Entry P51606

    ProtoNet protein and cluster: P51606

    1 Blocks protein domain: IPB010819 N-acylglucosamine 2-epimerase

    UniProtKB/Swiss-Prot: RENBP_HUMAN, P51606
    Similarity: Belongs to the N-acylglucosamine 2-epimerase family


    RENBP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RENBP_HUMAN, P51606
    Function: Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a
    protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the
    N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of
    Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded
    Catalytic activity: N-acyl-D-glucosamine = N-acyl-D-mannosamine

         Genatlas biochemistry entry for RENBP:
    renin binding protein,involved in the regulation of the renin-angiotensin system

         Enzyme Number (IUBMB): EC 5.1.3.81 2

         Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004476mannose-6-phosphate isomerase activity IEA--
    GO:0004857enzyme inhibitor activity ----
    GO:0004866endopeptidase inhibitor activity TAS9285790
    GO:0005524ATP binding IEA--
         
    RENBP for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Renbp):
     homeostasis/metabolism  renal/urinary system 

    RENBP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Renbptm1Csch for RENBP

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RENBP 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RENBP About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Amino sugar and nucleotide sugar metabolism
    Amino sugar and nucleotide sugar metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for RENBP):
        Amino sugar and nucleotide sugar metabolism

    UniProtKB/Swiss-Prot: RENBP_HUMAN, P51606
    Pathway: Amino-sugar metabolism; N-acetylneuraminate degradation


    RENBP for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RENBP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/11 Interacting proteins for RENBP (P516062, 3 ENSP000003773034) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZBED1O960062, 3, ENSP000003706164MINT-68359 I2D: score=5 STRING: ENSP00000370616
    RENP007973, ENSP000002721904I2D: score=1 STRING: ENSP00000272190
    GNEENSP000003798394STRING: ENSP00000379839
    HEXAENSP000002680974STRING: ENSP00000268097
    HEXBENSP000002614164STRING: ENSP00000261416
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006013mannose metabolic process IEA--
    GO:0006044N-acetylglucosamine metabolic process IEA--
    GO:0006051N-acetylmannosamine metabolic process IEA--
    GO:0008217regulation of blood pressure TAS9285790
    GO:0010951negative regulation of endopeptidase activity ----

    RENBP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RENBP for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RENBP

    3 HMDB Compounds for RENBP    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    N-Acetyl-D-glucosamine2-(acetylamino)-2-deoxyhexose (see all 9)7512-17-6--
    N-Acetylmannosamine2-Acetamido-2-deoxy-D-mannose (see all 3)3615-17-6--

    1 DrugBank Compound for RENBP    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    N-Acetyl-D-glucosamine2-Acetamido-2-deoxy-D-glucose (see all 4)7512-17-6target--16011304 17349707 17565386 17292397

    8 Novoseek inferred chemical compound relationships for RENBP gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-acetylglucosamine 72.7 24 16011304 (2), 11275551 (2), 11926999 (2), 10502668 (2) (see all 9)
    mannose 6-phosphate 48.5 1 8735181 (1)
    sialic acid 40 7 12499362 (3), 19707758 (2), 15987957 (1)
    rapamycin 23.4 1 1563628 (1)
    leucine 15.7 4 1723410 (3)
    atp 5.16 8 11926999 (1), 11726282 (1), 9990133 (1)
    cysteine 2.31 4 10502668 (2), 11275551 (1)
    serine 0 1 11275551 (1)

    Search CenterWatch for drugs/clinical trials and news about RENBP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RENBP gene: 
    NM_002910.5  

    Unigene Cluster for RENBP:

    Renin binding protein
    Hs.158331  [show with all ESTs]
    Unigene Representative Sequence: NM_002910
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393700 ENST00000457282 ENST00000369997 ENST00000423624 ENST00000451114
    ENST00000442361 ENST00000462086 ENST00000464227 ENST00000471056 ENST00000475904
    ENST00000412763(uc004fjo.2 uc011mzh.1)
    miRNA
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    Additional mRNA sequence: 

    AK298125.1 BC015558.2 D10232.1 

    5 DOTS entries:

    DT.91695494  DT.100023512  DT.99997872  DT.100746718  DT.121317632 

    24/45 AceView cDNA sequences (see all 45):

    CR601292 CA976102 BI822024 BC015558 BI753232 BQ002857 CD368393 BQ683160 
    BU784500 CA308512 BX280654 BM675574 BU784428 BM719661 BE277254 BX390368 
    BG910783 BX371652 AI539009 BI836864 BI908480 BU157608 CA309049 D10232 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RENBP    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                                          
    SP2:                                                  -           -                           
    SP3:                                                                                          


    ECgene alternative splicing isoforms for RENBP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RENBP expression in normal human tissues (normalized intensities)      RENBP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RENBP Expression
    About this image


    RENBP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/10 selected tissues (see all 10) fully expand
     
     Melanocytes (Integumentary System)    fully expand to see all 3 entries
             Human EpiDermal Melanocytes-medium (HEM-m)   
     
     Epidermis (Integumentary System)    fully expand to see all 3 entries
             Human EpiDermal Melanocytes-medium (HEM-m)   
     
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             PureStem endothelial progenitor 30-SM2-1
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Kidney (Urinary System)
             kidney ; cells in tubules   

    See RENBP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RENBP

    SOURCE GeneReport for Unigene cluster: Hs.158331
        SABiosciences Custom PCR Arrays for RENBP
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for RENBP gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Renbp1 , 5 renin binding protein1, 5 84.45(n)1
    85.65(a)1
      X (37.49 cM)5
    197031  NM_023132.31  NP_075621.31 
     739221215 
    lizard
    (Anolis carolinensis)
    Reptilia RENBP6
    Uncharacterized protein
    65(a)
    1 ↔ 1
    2(88341111-88358465)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.237592 Xenopus laevis transcribed sequence with weak similarity more 75.42(n)    CF519989.1 
    zebrafish
    (Danio rerio)
    Actinopterygii renbp1 renin binding protein 64.11(n)
    63.17(a)
      791728  NM_001126443.1  NP_001119915.1 


    ENSEMBL Gene Tree for RENBP (if available)
    TreeFam Gene Tree for RENBP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RENBP gene
    4 SIMAP similar genes for RENBP using alignment to 6 protein entries:     RENBP_HUMAN (see all proteins):
    UTY    NF2    ZNF564    AURA2

    RENBP for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RENBP
    PGOHUM00000242089


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/200 SNPs in RENBP are shown (see all 200)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1999196631,2
    --153202694(+) ATAAA-/TAAAAA 2 -- int10--------
    rs568211101,2
    C--153202697(+) ATAAA-/TAAA/TAAATAA
    A
    /TAAATAAATAAA
    AACTA
    4 -- int1 cds10--------
    rs1463608691,2
    C--153202706(+) TAGTTA/CTGTGT 2 -- int10--------
    rs1824080371,2
    --153202738(+) TTACAC/TTGTTC 2 -- int10--------
    rs1397768911,2
    C--153203077(+) TATTTA/TTTTTA 2 -- int10--------
    rs1858832801,2
    --153203139(+) TTCCCA/GGGTTC 2 -- int10--------
    rs1117850601,2
    C,F--153203337(+) GCCACT/CGCGAC 2 -- int11Minor allele frequency- C:0.00CSA 1
    rs48984631,2
    C,A--153203390(+) tgttgG/Accagg 2 -- int11Minor allele frequency- A:0.00NA 1
    rs1917777611,2
    --153203628(+) TAGCTA/GCAGGT 2 -- int10--------
    rs1486166071,2
    C--153203785(+) ACTCAC/TAATGG 2 -- int10--------

    HapMap Linkage Disequilibrium report for RENBP (153200716 - 153210232 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RENBP:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv33199CNV Gain+Loss17666407
    nsv469867CNV Complex16826518


    Locus Specific Mutation Databases (LSDB): RENBP
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 312420    OMIM disorders: --

    9 diseases for RENBP:    About MalaCards
    sialuria    wilms tumor    proteinuria    rhinitis
    allergic rhinitis    myopathy    vascular disease    essential hypertension
    hypertension

    2 diseases from the University of Copenhagen DISEASES database for RENBP:
    Allergic rhinitis     Toxocariasis

    RENBP for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for RENBP gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    wilms tumor 35.1 1 1587805 (1)
    essential hypertension 20.5 1 9285790 (1)
    renal disease 0 1 8897555 (1)

    Genetic Association Database (GAD): RENBP
    Human Genome Epidemiology (HuGE) Navigator: RENBP (6 documents)

    Export disorders for RENBP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RENBP gene, integrated from 9 sources (see all 56):
    (articles sorted by number of sources associating them with RENBP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic and molecular properties of human and rat renin-binding proteins with reference to the function of the leucine zipper motif. (PubMed id 1723410)1, 2, 9 Inoue H.... Miyake Y. (1991)
    2. Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2- epimerase. (PubMed id 9990133)1, 2, 9 Takahashi S....Kobayashi M. (1999)
    3. Human renin binding protein: complete genomic sequence and association of an intronic T/C polymorphism with the prorenin level in males. (PubMed id 9285790)1, 4, 9 Knoll A....Rosenthal A. (1997)
    4. The human gene for renin-binding protein. (PubMed id 1618798)1, 3, 9 Takahashi S....Miyake Y. (1992)
    5. Angiotensin converting enzyme DD genotype is associated with hypertensive crisis. (PubMed id 12394950)1, 4, 9 Sunder-Plassmann G....Fodinger M. (2002)
    6. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease. (PubMed id 12446192)1, 4 Ortlepp J.R....Hoffmann R. (2002)
    9. Renin inhibits N-acetyl-D-glucosamine 2-epimerase (renin-binding protein). (PubMed id 11098137)1, 9 Takahashi S....Kawamura Y. (2000)
    10. Identification of a domain conferring nucleotide binding to the N-acetyl-d-glucosamine 2-epimerase (Renin binding protein). (PubMed id 11926999)1, 9 Takahashi S....Mori K. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5973 HGNC: 9959 AceView: RENBP Ensembl:ENSG00000102032 euGenes: HUgn5973
    ECgene: RENBP Kegg: 5973 H-InvDB: RENBP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RENBP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RENBP gene:
    Search GeneIP for patents involving RENBP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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