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REN Gene

protein-coding GIFtS: 59

GC01M204123

renin
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases & Descriptions
renin¹ ²		angiotensinogenase²
HNFJ2² ⁵		FLJ10761²
renin precursor, renal²		Angiotensinogenase³
angiotensin-forming enzyme²		EC 3.4.23.15³

External Ids:	HGNC: 9958¹	Entrez Gene: 5972²	Ensembl: ENSG00000143839⁷	UniProtKB: P00797³

Search outside databases for aliases for REN gene

Previous GC identifers: GC01M201847 GC01M199584 GC01M200484 GC01M201301 GC01M200855 GC01M202390

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for REN:

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone

release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form

angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of

blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from

alternative splicing and the use of alternative promoters have been described, but their full-length nature has not

been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. (provided by RefSeq)

UniProtKB/Swiss-Prot: RENI_HUMAN, P00797

Function: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from

angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and

increased sodium retention by the kidney

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
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Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the REN gene upstream (promoter) region

:
AP-1 deltaCREB CREB c-Jun c-Fos ATF-2 PPAR-gamma2 PPAR-gamma1 GATA-6 SREBP-1c

Epigenetics:

Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for REN

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32

REN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M204123: view genomic region (about GC identifiers)

Start:	204,123,944 bp from pter
End:	204,135,465 bp from pter
Size:	11,522 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000001.10 NT_004487.19

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: RENI_HUMAN, P00797 (See protein sequence)

Recommended Name: Renin precursor

Size: 406 amino acids; 45057 Da

Subunit: Interacts with ATP6AP2

Subcellular location: Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2

PDB structures from and Proteopedia :

1BBS (3D)

1BIL (3D)

1BIM (3D)

1HRN (3D)

1RNE (3D)

2BKS (3D)

2BKT (3D)

2FS4 (3D)

2G1N (3D)

2G1O (3D)

2G1R (3D)

2G1S (3D)

2G1Y (3D)

2G20 (3D)

2G21 (3D)

2G22 (3D)

2G24 (3D)

2G26 (3D)

2G27 (3D)

2I4Q (3D)

2IKO (3D)

2IKU (3D)

2IL2 (3D)

2REN (3D)

2V0Z (3D)

2V10 (3D)

2V11 (3D)

2V12 (3D)

2V13 (3D)

2V16 (3D)

3D91 (3D)

3G6Z (3D)

3G70 (3D)

3G72 (3D)

3GW5 (3D)

3K1W (3D)

3KM4 (3D)

Secondary accessions: Q6FI38 Q6T5C2

Alternative splicing: 2 isoforms: P00797-1 P00797-2

REFSEQ proteins: NP_000528.1

ENSEMBL proteins:

ENSP00000272190 ENSP00000356163

Human Recombinant Proteins

	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for REN
	R&D Systems Recombinant & Natural Proteins for REN (Renin)
	Enzo Life Sciences proteins for REN
	HuPro® and/or Recombinant Proteins from Abnova for REN
	Origene Purified Recombinant Human Protein: REN
	Novus Biologicals Protein for REN
	Novus Biologicals Lysate for REN
	Sino Biological Recombinant Protein for REN

5/6 Gene Ontology (GO) cellular component terms (GO ID links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	IDA	12045255
GO:0005737	cytoplasm	IDA	18029348
GO:0016020	membrane	IEA	--
GO:0043231	intracellular membrane-bounded organelle	IDA	18029348

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REN for ontologies About GeneDecksing

Antibodies for REN:

	Millipore Mono- and Polyclonal Antibodies for the study of REN
	Sigma-Aldrich Antibodies for REN
	R&D Systems Antibodies for REN (Renin)
	Monoclonal and Polyclonal Antibodies from Abnova (REN)
	Browse Origene Antibodies
	Novus Biologicals Antibodies for REN
	Browse antibodies at Epitomics

Assays for REN:

	Browse Kits and Assays available from Millipore
	Browse ELISAs at Sigma-Aldrich
	Browse R&D Systems for biochemical assays
	Enzo Life Sciences assays for REN

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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REN for domains About GeneDecksing

5 InterPro domains/families:

IPR021109 Peptidase_aspartic

IPR009007 Peptidase_aspartic_catalytic

IPR001969 Peptidase_aspartic_AS

IPR012848 Propep_A1

IPR001461 Peptidase_A1

Graphical View of Domain Structure for InterPro Entry P00797

ProtoNet protein and cluster: P00797

1 Blocks protein family: IPB001461 Pepsin (A1) aspartic protease family signature

UniProtKB/Swiss-Prot: RENI_HUMAN, P00797

Similarity: Belongs to the peptidase A1 family

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (REN)
		Origene 29mer shRNA kits in GFP-retroviral vector: REN Origene shRNA RFP: REN Origene basic RS shRNA: REN
		Applied Biosystems Silencer® siRNAs for REN
		Sigma-Aldrich siRNA Panels and siRNA for REN Sigma-Aldrich shRNA Panels and shRNA for REN Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		Origene GFP tagged cDNA clones in CMV expression vector: REN Origene Myc/DDK tagged cDNA clones in CMV expression vector: REN Origene untagged cDNA clones in CMV expression vector: REN
		Browse Sino Biological Human cDNA Clones

UniProtKB/Swiss-Prot: RENI_HUMAN, P00797

Function: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from

angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and

increased sodium retention by the kidney

Catalytic activity: Cleavage of Leu- -Xaa bond in angiotensinogen to generate angiotensin I

Enzyme regulation: Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing

Biophysicochemical properties: Kinetic parameters: KM=1 uM for angiotensinogen (in absence of ATP6AP2); KM=0.15 uM for

angiotensinogen (in presence of membrane-bound ATP6AP2);

Enzyme Number (IUBMB): EC 3.4.23.15

Genatlas biochemistry entry for REN:

renin,40kDa,angiotensin-forming enzyme

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004190	aspartic-type endopeptidase activity	IDA	12045255
GO:0005102	receptor binding	IPI	12045255
GO:0005159	insulin-like growth factor receptor binding	IEA	--
GO:0008233	peptidase activity	IDA	12045255

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REN for ontologies About GeneDecksing

Animal Models: 11 MGI mutant phenotypes (inferred from 9 alleles) (MGI details for Ren1):

behavior/neurological	cardiovascular system	growth/size	homeostasis/metabolism	immune system
lethality-postnatal	muscle	nervous system	normal	renal/urinary system
reproductive system

REN for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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REN for pathways About GeneDecksing

1 Millipore Pathway for REN

Selected targets of CREB1

2 Sigma-Aldrich "Your Favorite Gene" Pathways for REN (Your Favorite Gene powered by Ingenuity)

	Lysine Degradation
	Renin-Angiotensin Signaling

1 GeneAssist Pathway for REN

Renin-Angiotensin Pathway

1 Kegg Pathway (Kegg details for REN):

hsa04614 Renin-angiotensin system

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for REN

1 Interacting protein for REN (P00797²) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KCTD15	Q96SI1²	MINT-65369

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5/15 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 15 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001822	kidney development	IMP	16116425
GO:0001823	mesonephros development	--	--
GO:0002003	angiotensin maturation	IDA	12045255
GO:0002016	regulation of blood volume by renin-angiotensin	IEA	--
GO:0006508	proteolysis	IDA	12045255

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REN for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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REN for compounds About GeneDecksing

Enzo Life Sciences drugs & compounds for REN

Sigma-Aldrich Small Molecules for REN:

Small Molecule - Inhibitor

Browse Tocris compounds for REN
10/1247 Novoseek chemical compound relationships for REN gene (see all 1247 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
sodium	100.00	3286	7911056 (8), 10725 (8), 9369279 (7), 9170003 (7) (see all 100)
aldosterone	100.00	7964	14583438 (8), 12406976 (8), 9822455 (7), 9688237 (7) (see all 100)
potassium	100.00	1066	4319970 (12), 6428366 (7), 4319969 (7), 1333446 (7) (see all 100)
furosemide	100.00	734	3276725 (6), 3105853 (6), 9170004 (5), 884392 (5) (see all 100)
saralasin	100.00	237	713415 (6), 1269103 (6), 120320 (6), 7020064 (5) (see all 100)
isoproterenol	100.00	537	7028620 (7), 7039349 (6), 480253 (6), 15737 (6) (see all 100)
captopril	100.00	998	7004721 (7), 8738111 (6), 3078272 (6), 8021469 (5) (see all 100)
propranolol	100.00	582	236325 (6), 879001 (5), 6996661 (5), 637424 (5) (see all 100)
enalapril	100.00	275	2260680 (5), 10193670 (5), 2837909 (4), 2159503 (4) (see all 100)
epinephrine	100.00	560	6372523 (6), 3309520 (6), 3279810 (6), 7826555 (4) (see all 100)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
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Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (REN)
		Applied Biosystems Silencer® siRNAs: NM_000537
		Origene 29mer shRNA kits in GFP-retroviral vector: REN Origene shRNA RFP: REN Origene basic RS shRNA: REN
		Sigma-Aldrich siRNA Panels and siRNA for REN Sigma-Aldrich shRNA Panels and shRNA for REN Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:

Search SABiosciences for microRNAs that regulate REN:

Assays:

Applied Biosystems TaqMan® Gene Expression Assays:

NM_000537

Clones:

Origene GFP tagged cDNA clones in CMV expression vector: REN
Origene Myc/DDK tagged cDNA clones in CMV expression vector: REN
Origene untagged cDNA clones in CMV expression vector: REN

Primers:		Origene genome-wide validated SYBR primer pairs: REN
		SABiosciences RT2 qPCR Primer Assay for REN: PPH07193A

REFSEQ mRNAs for REN gene:

NM_000537.3

Additional cDNA sequence:

AF117822.1 BC033474.1 BC047752.1 CR536498.1 X00063.1

2 DOTS entries:

DT.411947 DT.121384325

24/47 AceView cDNA sequences (see all 47 ):

BM543760 BC047752 AW513938 CB044005 AW445055 CB044993 CB045004 BI759718

CB044002 AW771349 CB853064 CB044992 CB044030 BX108221 CR536498 BC033474

AW615180 X00063 BI762506 AW513368 CB044006 BI517900 BI761258 BM906275

highest scoring ESTs for REN:

BC033474 BC047752 BI759718 BI761258 BI762506 BM543760 BM906275 CB044006 CB044031 AA253258

Unigene Cluster for REN:

Renin

Hs.3210 [show with all ESTs]

Unigene Representative Sequence: NM_000537

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000272190 ENST00000367195

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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REN expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for REN

¹ / ² / ³

3 probe-sets matching REN gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39655_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M26901	0.20	1.00	0.72	1
206367_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000537	0.60	1.00	0.82	1
206367_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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REN for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
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About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.3210

Primers:		Origene genome-wide validated SYBR primer pairs: REN
		SABiosciences RT2 qPCR Primer Assay for REN: PPH07193A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for REN gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	REN¹	--	renin	80.9(n) 72.86(a)	403838 NM_001003194.1 NP_001003194.1
chimpanzee (Pan troglodytes)	REN¹	--	renin	99.26(n) 100(a)	469651 NM_001009122.1 NP_001009122.1
cow (Bos taurus)	REN¹	--	renin	80(n) 74.5(a)	511831 XM_589248.3 XP_589248.3
rat (Rattus norvegicus)	Ren¹	--	renin	76.42(n) 67(a)	24715 NM_012642.3 NP_036774.3
mouse (Mus musculus)	Ren1^{1, 5}	1 (69.90 cM)⁵	renin 1 structural^{1, 5}	77.72(n)¹ 70.85(a)¹	19701¹ NM_031192.2¹ NP_112469.1¹ AF117821⁵ AK052685⁵ (see all 24)

About this table Species with no ortholog for REN

ENSEMBL Gene Tree for REN

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for REN gene

NAPSB² PGA5² BACE1² CTSD² BACE2² PGA3² NAPSA² CTSE²

PGC²

REN for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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10/34 NCBI SNPs in REN are shown (see all 34 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 69)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Related Data				Allele Frequencies
				--	--	--		--	--			--
--	rs6668858^1,2	C,F,A,H	175300804(+)	`CAAGCG/ATAAAA`	1	--	ng5¹		10	NS EA NA	776
--	rs6681776^1,2	C,F,A	175301644(+)	`cttccC/Tcttcc`	1	--	ng5¹ trp³		15	NS EA NA WA	1030
	rs6682082^1,2	C,F,A	175301957(+)	`ctttgC/Tgtttt`	1	--	ng5¹		13	NS EA NA WA	1356
	rs5705^1,2	C,F,O,A	204131186(-)	`CTGACA/C/G/T CTTGG`	4	T	ref¹ syn¹ ese³		26	MN NS EA NA WA	4032
	rs1464816^1,2	C,F,O,A,H	175293870(+)	`GTATTG/TCCTCA`	1	--	int¹		38	NA EA MN NS WA	5266
--	rs2887284^1,2	C,F,O,A	175289824(+)	`GGATTA/CTTGGG`	1	--	int¹		25	NS EA NA WA	2514
	rs5707^1,2	C,F,A,H	175294687(-)	`CGCCCT/GAGGTC`	1	--	int¹		22	MN EA NS NA WA	4392
	rs1917539^1,2	C,F,O,A	175294570(-)	`ACCCTA/GCTCTG`	1	--	int¹		14	NA EA MN NS WA	1414
--	rs2177695^1,2	C,F,H	175299277(+)	`CGCCCG/AGCTAA`	1	--	int¹		4	NS	282
--	rs6676458^1,2	C,F,A	175292531(+)	`CCCACT/CTCCTC`	1	--	int¹		3	NA WA	124

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HapMap Linkage Disequilibrium images for REN (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for REN: --

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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REN for disorders About GeneDecksing

OMIM: 179820

UniProtKB/Swiss-Prot: RENI_HUMAN, P00797

Defects in REN are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive

severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably

due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype)

10/1051 Novoseek disease relationships for REN gene (see all 1051 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hypertension	100.00	2785	870227 (6), 8498972 (5), 713415 (5), 6374506 (5) (see all 100)
hypertension renal	100.00	137	790007 (3), 4331798 (3), 1152349 (3), 1132078 (3) (see all 100)
hypertension; renovascular	100.00	456	9486089 (6), 3044993 (5), 9453303 (4), 8727869 (4) (see all 100)
hyponatremia	100.00	273	7911056 (7), 10725 (5), 7737709 (4), 6376345 (4) (see all 100)
renal artery stenosis	100.00	174	9488241 (5), 929140 (2), 8129537 (2), 796975 (2) (see all 100)
essential hypertension	100.00	1141	8411837 (4), 7606651 (4), 6109626 (4), 3058795 (4) (see all 100)
low renin hypertension	100.00	111	6993721 (5), 891220 (4), 7004721 (4), 14504 (4) (see all 78)
hypotensive	100.00	290	2412016 (4), 902672 (3), 846681 (3), 7033921 (3) (see all 100)
aldosteronism primary	100.00	413	1727806 (5), 12406976 (5), 9522976 (4), 12354127 (4) (see all 100)
enzyme inhibition	99.72	157	7994817 (4), 6293741 (3), 6160938 (3), 1396304 (3) (see all 100)

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Human Gene Mutation Database: REN
Genetic Association Database: REN
Human Genome Epidemiology Navigator: REN (174 documents)

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/3445 PubMed articles for REN gene (see all 3445 ):

Strong association of a renin intronic dimorphism with essential hypertension. (PubMed id 16138564)^{1, 3, 6} Ahmad U....Frossard P.M. (2005)
A novel variable number of tandem repeat polymorphism of the renin gene and essential hypertension. (PubMed id 12862204)^{1, 3, 6} Hasimu B....Ozawa Y. (2003)
Haplotypes of the human renin gene associated with essential hypertension and stroke. (PubMed id 11224002)^{1, 3, 6} Frossard P.M....Kane J.P. (2001)
Lack of correlation between Mbo I restriction fragment length polymorphism of renin gene and essential hypertension in Japanese. (PubMed id 11409653)^{1, 3, 6} Fu Y....Ogihara T. (2001)
Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis. (PubMed id 16116425)^{1, 3, 4} Gribouval O.... Gubler M.-C. (2005)
Association study between the human Renin gene and preeclampsia. (PubMed id 16036389)^{1, 3, 6} Maruyama A....Yamamoto T. (2005)
Angiotensin converting enzyme DD genotype is associated with hypertensive crisis. (PubMed id 12394950)^{1, 3, 6} Sunder-Plassmann G....Fodinger M. (2002)
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. (PubMed id 12045255)^{1, 3, 4} Nguyen G.... Sraer J.-D. (2002)
Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes. (PubMed id 11803527)^{1, 3, 6} Taylor A....Rubinsztein D.C. (2001)
Relationship between the renin-angiotensin system genes and diabetic nephropathy in the Chinese. (PubMed id 11776100)^{1, 3, 6} Wu S....Li J. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
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Entrez Gene: 5972	HGNC: 9958	AceView: REN	Ensembl:ENSG00000143839	euGenes: HUgn5972
ECgene: REN	Kegg: 5972	H-InvDB: REN

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Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Renin

Intellectual Property for REN gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

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Patent Information for REN gene:

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GeneCards and IP:

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Products for REN:

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Category			ACSF3 acyl-CoA synthetase family member 3
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REN Gene

protein-coding GIFtS: 59

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diabetic ketoacidosis
adrenal suppression
alcohol intoxication
varicocele
cardiac tamponade
malformation
arthritis reactive
fibrosis myocardial
hyperthyroid
supraventricular tachycardia
familial diabetes insipidus
laron syndrome
epilepsies
fetal complications
cardiovascular disease other
african trypanosomiasis
hematocrit change
venous disease
adrenal carcinoma
apnea
anterior myocardial infarction
hypoglycemia
high-risk pregnancies
apoa1
htlv-i
kidney stone
osteolysis
atopic
adpkd
arteriolonephrosclerosis
hypertension malignant
restriction site polymorphism
sclerosis; systemic
abdominal aortic aneurysm
hepatitis viral
vascular embolism
hyperemia
left renal artery stenosis
metastasis
chagas disease
acidosis respiratory
thrombocytosis
liver hypoxia
block; conduction
dengue hemorrhagic fever
vasculitis
chronic glomerulonephritis
arteritis
cardiac; fibrosis
acute respiratory failure
emotional stress
renal fibrosis
osteoporosis
beta-thalassemia
endocrinopathy
atrophy; olivopontocerebellar
17 alpha-hydroxylase deficiency
pseudohypoparathyroidism, type ib
hypoplasia
gh deficiency
arteriovenous fistula
hypertrophy; ventricular; right
orbital tumor
abdominal pregnancies
disuse muscle atrophy
occlusion; vessel
failure respiratory
kidney functional
renal atrophy
hypertensive nephropathy
postinfarction
cystic hygroma
active chronic hepatitis
dilatations
failure right heart
chronic heart failure
lupus erythematosus systemic
fatty liver
damage liver
polycythemia
growth suppression
infertility
hyperaldosteronism, familial, type i
fulminant hepatic failure
congenital atresia
inflammatory disease
angioedema
breast cancer
infarction; myocardial
hypercholesterolemia
antidiuresis
hyperemia; renal
depression endogenous
hyperreninemic hypoaldosteronism
polyarteritis nodosa
nephritis autoimmune
hyperglycemia
cervical cancer
anemia
aortic atresia
fibrillation
budd-chiari syndrome
hypertension, pregnancy-induced
acute viral hepatitis
oedema peripheral
glioma
renal cirrhosis
psychological stress
carboxyhemoglobinemia
carcinoma; renal cell
atherosclerotic renal artery stenosis
unilateral hyperplasia
acidosis renal tubular
disturbance; circulatory
cardiovascular morbidity
ventricular couplet
metastatic renal cell carcinoma
delayed graft function
background retinopathy
portal vein thrombosis
autonomic disorder
hemorrhage; intraventricular
cushing disease
VSD
hypocortisolism
vascular encephalopathy
kwashiorkor; marasmic
parenchymal renal hypertension
encephalopathies
complicated pregnancy
borderline hypertension
glomerulonephritis
hypertension; renovascular
von willebrand
alkalosis hypochloremic
angiotensin hypertension
delivery preterm
mitral (valve) prolapse
microalbuminuria
embolism pulmonary
idiopathic edema
fetal alcohol syndrome
depletion; potassium
mitral valvular disease
anovulatory infertility
hyperthyroidism
proximal renal tubular acidosis
multicystic dysplastic kidney
obstruction
chronic congestive heart failure
thrombocytopenia
diabetic microangiopathies
falciparum malaria
hypertension secondary
dysgenesis; gonadal
familial dysautonomia
bilateral renal artery stenosis
carotid occlusion
systolic dysfunction
asphyxia; fetal
bilateral hydronephrosis
pheochromocytoma
celiac disease
vitamin d deficiencies
hypercalciuria
acute liver damage
insufficiency; vascular
response, acute phase
hypertension; white coat
hyperplasia
HUS
gene insertion
infarct
underdevelopment
congenital diaphragmatic hernia
leukemia
hypertensive emergency
erectile dysfunction
hydatidiform mole
intraoperative hypertension
compensatory hypertrophy
arteriosclerosis
bronchitis chronic
gastric ulcer
dysfunction kidney
eosinophilia
spontaneous subarachnoid hemorrhage
polycystic kidney disease
congestion
premature newborn
CAD
renal oncocytoma
cardiomyopathies
atopic dermatitis
solitary kidney
fistula, arteriovenous, renal
angioedema; hereditary
fistula
infection viral
hemolytic disease
nephrotic range proteinuria
lymphocele
edema pulmonary
hyperlipidemia
iugr
diabetes; type 2
catecholamine; secretion
acute anterior myocardial infarction
hypotension symptomatic
asthma
heart failure nyha class ii
seminoma
disease; urological
microscopic polyarteritis
obstructive uropathy
acidosis metabolic
cardiovascular risk factor
neurological disorder
scleroderma
malnutrition
tuberculosis
proteinuria
obstruction; renal artery
pseudohypoparathyroidism
clear cell carcinoma
androgen insensitivity syndrome
death neonatal
venous hypertension
myoglobinemia
sarcoma
hypersensitivities
disease; ischemic heart
mood disorder
renin-dependent hypertension
prolactinoma
left ventricular diastolic dysfunction
serous effusion
graft dysfunction
VUR
abnormal secretion
cerebral palsy
charcot-marie-tooth disease
chronic hyperkalemia
calcification
nephrosclerosis
cardiosclerosis
CKD
bleeding; uterine
polydipsia psychogenic
hypertension portal
complications; vascular
fluid imbalance
septicemia
cardiogenic shock
alkalosis hypokalaemic
AD
hypocalciuria
benign essential hypertension
infarction; renal
restenosis
coarctation
infectious
low-renin essential hypertension
islet cell carcinoma
reactive hyperemia
ovarian tumor
overtransfusion
high output heart failure
mesangial proliferation
juxtaglomerular cell tumor
myxedema
low output heart failure
renal tumor
pseudohypoaldosteronism
herpes simplex
vascular dilation
brain death
uncontrolled hypertension
interstitial nephritis
sickle cell nephropathy
arteriopathy
acute cerebrovascular disease
hypertrophy; ventricular; left
high renin hypertension
acidosis respiratory acute
estrogenic effect
recurrent wilms tumor
aldosterone hypertension
congenital renal dysgenesis
disease; menieres
reflux
atherogenesis
arrhythmia atrial
glucocorticoid resistance
fibrosis liver
exercise proteinuria
azotemia
postoperative hypertension
cell injury
thyrotoxicosis
autonomic failure
refractory heart failure
hydronephrosis
htlv-i-associated myelopathies
malnutrition; protein
colon cancer
tetanus
fibrinoid necrosis
benign kidney tumor
heart ca
cardiovascular abnormalities
labor preterm
sickness, motion
albino
pituitary disease
decompression sickness
diffuse toxic goiter
mitral regurgitation
valvular heart disease
fenestration
hypovolemic shock
immaturity
compensated cirrhosis
adrenocortical carcinoma
alkalosis metabolic
low cardiac output syndrome
liver dysfunction
neuropathy
undifferentiated carcinoma
struma ovarii
menorrhagia
fluid retention
juxtaglomerular cell hyperplasia
cerebrovascular disease
steroid-sensitive nephrotic syndrome
leiomyosarcoma
vascular disease
abdominal tumor
syncope vasovagal
chloride deficiency
choriocarcinoma
adrenal cortex; hyperactivity
alhe
sepsis
microangiopathy
malaria
erythroleukemia
transient ischemia
diabetic retinopathy proliferative
gitelman syndrome
nephrosclerosis hypertensive
aneurysm cerebral
hyperparathyroidism secondary
fibromuscular hyperplasia
damage; renal
increased; permeability
apnea; sleep
hypertension ocular
chronic myocardial ischemia
shock
cerebral infarction
HCM
aortocaval fistula
renal impairment
hypertension
cysts
arrhythmia
hypochloremia
hypertension; maternal
failure; ventricular; left
preeclampsia
incipient diabetic nephropathy
tumor progression
carotid stenosis
deficiency; magnesium
cardiac event
liver hamartoma
failure; ventricular
fetal hypoxia
hypertensive heart disease
anovulatory
hyperlipoproteinemia
eruption
human immunodeficiency virus
acute nephritis
fetal stress
leydig cell tumor
neurofibromatosis
aggressive behavior
infection urinary tract
mitral stenosis
adrenocortical hyperplasia
pseudo-bartter syndrome
cardiomyopathy hypertensive
abstinence syndrome
jaundice obstructive
artery; spasm
osteochondritis
dysautonomia
effusion pericardial
obstructive sleep apnea
aortitis
hypertension; renal artery stenosis
aortic occlusion
hypoaldosteronism
parathyroid adenoma
disease obstructive lung
distal renal tubular dysfunction
primary tumor
lesion; vascular
diabetic retinopathies
nephrotic syndrome
tumor necrosis
preterm infant
hyperphosphatemia
cor pulmonale
ulcer
salt-losing nephropathy
vasopressin decreased
cardiomyopathy dilated
circulation; fetal
crisis; renal
renal ischemia
pulmonic stenosis
retinal vascular
anti-gbm disease
failure; renal
congenital hyperplasia
alkalosis metabolic hypokalemic
mineralocorticoid deficiency
asthmaticus; status
dysfunction; myocardial
potassium, decreased level
myelopathies
hyperparathyroidism
arterial hemorrhage
paraplegia
multiple renal arteries
diabetes mellitus
early cirrhosis
shutdown renal
abuse; laxatives
sustained diastolic hypertension
damage; vascular
pregnancy early
carbohydrate; intolerance
bleeding gastrointestinal
acute right heart failure
arteritis; necrotizing
renal arteriovenous malformation
alcohol withdrawal
acute renal insufficiencies
congenital deficiencies
syndrome, zollinger-ellison
peripheral vasodilatation
syndrome; turner
lupus nephritis
primary hyperplasia
bilateral hyperplasia
rare disorder
21-hydroxylase deficiency
nelson syndrome
goldblatt hypertension
metabolic disturbance
nephritis
acute myocardial infarction
SAH
gestosis
hypoxic
potassium serum increased
biliary obstruction
fibromuscular dysplasia
hemodynamic instability
low t3 syndrome
brain; ischemic
polyhydramnios
anabolic steroids
coronary atherosclerosis
hypothalamic; lesion
deficiency; hormone
defect; vascular
hypercalcemia
acute pancreatitis
compensated metabolic acidosis
inflammation
acute glomerulonephritis
neurogenic hypertension
right renal artery stenosis
nephrotoxic acute renal failure
cyst; follicular
autonomic neuropathy
cyst; renal
glioblastoma
fibrillation ventricular
bright disease
hypertension renal
cushing syndrome
change; vasomotor
phenomenon; raynaud
disease; heart
hyperuricemia
rhinovirus
anemia megaloblastic
malignant renovascular hypertension
cold ischemia
lipid deposition
diseases; multiple
osteoarthritis
vasospasm
breast tumor
endocrine hypertension
transient cerebral ischemia
paraganglioma
uremia
decompensated cirrhosis
renal disease progressive
class i; histocompatibility complex
cavitation
hyperparathyroidism primary
reactive hypertension
adrenal tumor
hyalinization
asthma chronic
other acute renal failure
cholera
genetic disorder
reflux; vesicoureteral
minimal lesion
arthritis
hypothyroid
thromboembolism
complications; renal
lung tumor
adrenal disease
relapse
hypotropia
insufficiency; placental
cystic fibrosis
hyponatremic
familial hypertriglyceridemia
acidemia
aneurysm; renal artery
electrolyte imbalance
primary pulmonary hypertension
atherosclerosis
asphyxia
metaplasia
hypertensive heart failure
headache vascular
massive infarct
neuroblastoma
perinephritis
rheumatoid vasculitis
diabetes mellitus insulin-dependent
volume overload
renin hypertension
uveitis
failure heart
heterotopia
renal pss
anaphylactic reaction
hydrothorax
cognitive impairment
diabetic complication
hemorrhage intracranial
congenital heart defect
marasmus
twin-twin transfusion syndrome
acute pyelonephritis
hypertension rebound
nephrosclerosis, malignant
left ventricular systolic dysfunction
hypotensive episode
bacterial peritonitis
metabolic syndrome
hypertension systolic
abdominal aortic coarctation
necrosis
acidosis
pkhd1
abortion threatened
peptic ulcer
hypocalcemia
glioblastoma multiforme
inferior vena cava obstruction
pyelonephritis
aminoaciduria
hypoosmolality
acute leukemia
hypotension, orthostatic
overhydration
aortic coarctation
hemangioblastoma
pituitary tumor
reflex bradycardia
decreased blood flow
cardiac death; sudden
renin induced hypertension
hyperparathyroid
occlusion; renal artery
dysfunction; renal tubular
adrenogenital syndrome
benign tumor
postoperative hypoparathyroidism
taste sweet
interstitial fibrosis
arterial embolization
peritonitis
valvular insufficiency
cystic disease
hemangiopericytoma
distortion
aplasia
insulin sensitivity
arteritis takayasu
autoimmune disease
fetal hemorrhage
arterial stenosis
ketonemia
diabetes insipidus nephrogenic
emphysema
insufficiency renal
moderate hydronephrosis
thyrotoxic periodic paralysis
brain; disease, organic
malignant secondary hypertension
neonatal anuria
cholesterolemia
effusion
lpl deficiency
hemorrhage intracerebral
brachydactyly
nonobstructive hypertrophic cardiomyopathy
CHF
short stature
morbid obesities
glucocorticoid deficiency
bladder outlet obstruction
chromophobe adenoma
renal angiomyolipoma
transgenic model
upper urinary tract infection
coronary occlusion
acute left ventricular failure
change; circulatory
acute myeloid leukemia
calcium deficiency
chronic allograft nephropathy
sodium; deficit
alcoholism
gas exchange impairment
total blood loss
bartter syndrome, classic
fluid loss
crisis hypertensive
ovary; polycystic (syndrome)
anastomosis
polycythemia vera
hypobetalipoproteinemia
enzyme inhibition
insulin resistance
sodium retention
hyporeninemic hypoaldosteronism
systolic hypertension, mild
conn adenoma
factor xii deficiencies
renal hypoplasia
preeclampsia, severe
tubulointerstitial nephritis
labor preterm treated
meconium aspiration syndrome
syndrome withdrawal
hyperplastic nodule
secondary adrenal insufficiency
jugular vein internal thrombosis
endometrial cancer
glucose tolerance impaired
biliary disease
acute renal disease
dysplasia
diastolic hypertension
narcotic withdrawal
end organ damage
premature ventricular contraction
fever; hemorrhagic
hypothyroidism primary
edema
lipoid nephrosis
extra-adrenal pheochromocytoma
ureteral obstruction
abdominal obesity
cancer
hypertension pulmonary
hydrocephalus
steroid cell tumor
chronic pyelonephritis
tachycardia ventricular
diffuse; peritonitis
vascular tumor
banti
nephropathy incipient
alveolar soft part sarcoma
pnets
bilateral adrenal hyperplasia
disorder sleep
brain tumor
hypoparathyroidism
multiple endocrine neoplasia type 1
hypertrophy; ventricular
hypertension iatrogenic
unilateral renal artery stenosis
functional failure
parkinsonism
ovarian failure primary
renal dysplasia
epithelial hyperplasia
acute hyperkalemia
atherosclerotic plaque
atrial flutter/ fibrillation
ovarian hyperstimulation
RA
fsgs
septic shock
chronic cor pulmonale
complete quadriplegia
alloxan diabetes
glucagonoma
cardiac; lesion
advanced cirrhosis
failure; aortic
hematologic malignancies
fast acetylator
cerebral ventricle
chronic renal failure
previous myocardial infarction
adrenal mass
potassium retention
localized disease
NDI
RDS
first myocardial infarction
arteriovenous malformation
drug-induced hypotension
disease graves
ischemic stroke
autoimmune
TTP
stricture
osteomalacia
concentric hypertrophy
inflammatory response
acute disease
tumor angiogenesis
renal tubular acidosis, type 4
blindness
hyperinsulinemia
adult t-cell leukemia
essential hypertension
enlargement; thymus
hyperadrenocorticism; pituitary-dependent
carcinoid syndrome
hypoglycemia; insulin
renovascular stenosis
ischemia
renal magnesium wasting
bartter syndrome
schizophrenia
tumor vasculature
shock; traumatic
renal scarring
arterial occlusion
functional disorder
disease; hodgkin
distress
alcoholic cirrhosis
glomerulosclerosis
trypanosomiasis
severe sepsis
hyperaldosteronism, familial, type ii
follicular ovarian cyst
hypertension uncomplicated
adrenal hyperplasia congenital
psychiatric disorder
effusion pleural
adhd
encephalopathy hepatic
stillborn
hyponatremia
alcohol; liver
insulin tolerance
adrenocortical tumor
scleroderma renal crisis
cardiac function impaired
severe hydronephrosis
microangiopathic haemolytic anaemia
unilateral renal hypoplasia
renal failure chronic hypertension
acute failure
postural tachycardia syndrome
chronic hypotension
acromegaly
venous occlusion
diuretic abuse
diabetic hyperglycemia
ALS
nephrosis
mastocytoma
diabetic autonomic neuropathies
retinopathies
nephroptosis
diphtheria
fibrous body
salt overload
hyperaldosteronism
massive hepatic necrosis
cardiac hypertrophy
stroke
trisomies
chronic liver disease
headache, tension-type
renal tuberculosis
chorioallantoic placenta
k deficiency
obstruction; ureteropelvic junction
thyroid disease
malnutrition; severe
hypouricemia
alcoholic cardiomyopathy
COPD
cardiorenal disease
aortic valve disease
gene fusion
disease; rheumatic heart
congenital heart disease
pediatric renal tumor
hypopituitarism
disease; liver
brain infarction
heartworm disease
hypertensive left ventricular hypertrophy
renal artery stenosis
electrolyte disturbance
cirrhosis (liver)
alkalosis metabolic acute
atresia biliary
asthma intrinsic
thrombus
hamartoma
endometrial tumor
fibrous dysplasia
aortic stenosis
embolism; vertebral artery
morphologic abnormality
hyperandrogenism
fibroplasia; retrolental
genetic hypertension
hyperprolactinemia
malabsorption
hypermagnesemia
glomus tumor
candidiasis
reflux nephropathy
atrial fibrillation
eclampsia
alkalosis
acute lymphoblastic leukemia
chronic hepatitis
hyperaldosteronism; secondary
chronic left ventricular failure
acute heart failure
renal infection
leukocytoclastic vasculitis
immediate hypersensitivities
hyperphagia
mitral disease
delirium tremens
erythrocytosis
arterial embolism
paracoccidioidomycosis
chorioamnionitis
multiple system atrophies
multiple myeloma
cirrhosis; portal
membranous nephropathies
DIC
moyamoya disease
unilateral renal atrophy
malformation venous
dyskinesia tardive
autonomic dysreflexia
disease; peripheral vascular
high-renin essential hypertension
ectopic pregnancies
arrhythmia ventricular
corticotroph adenoma
febrile reaction
pneumoperitoneum
lung cancer
physical stress
mineralocorticoid hypertension
left ventricle dilated
esophageal varices
infant sga
diabetic nephropathies
fistula; parotid
congestion pulmonary
hepatitis
acute pneumonia
sarcoidosis
acute poststreptococcal glomerulonephritis
vascular inflammations
diastolic dysfunction
thrombosis
precocious puberty
cardiovascular disease
cardiovascular pathology
segmental renal hypoplasia
change; vascular
delirium
glaucoma
right ventricular overload
aldosteronism primary
normal tension glaucoma
autonomic dysfunction
paraneoplastic hypokalemia
hormone replacement
disease parkinsons
obese
decompensated heart failure
ventricular dysfunction
panhypopituitarism
generalized seizure
deficiency; growth hormone
complete stenosis
encephalopathy hypertensive
left ventricular overload
ileal cancer
disease; lung
cyst; ovarian
chronic myeloid leukemia
congenital mesoblastic nephroma
hepatic impairment
pulmonary artery hypertension
cerebral ischemia
diabetes insipidus
proliferative retinopathy
renal hypertrophy
renal parenchymal disease
volume hypertension
obstruction; renal
left ventricular dysfunction
anxiety depression
lymphangioleiomyomatosis
acute hemorrhage
hypertension transient
cardiac decompensation
coronary; failure
adenoma; pituitary
cardiac autonomic neuropathy
occlusion; vascular
aneurysm
oncogenesis
IOP
atrophies
acute renal failure
pseudotumor
bipolar disorder
endothelial dysfunction
hypotensive
ketoacidosis
microhematuria
heart rate increased
withdrawal; drug
cardiovascular complication
ohss
disorder fetal
iga nephropathies
low renin hypertension
chest pain syndrome
cyst; epithelial
hypertrophies
adrenal; hyperplasia, congenital, salt-losing
diabetes; renal
adenoma
stasis
infant vlbw
chronic hypokalemia
thoracic neuroblastoma
orthostatic hypertension
narcosis
secondary erythrocytosis
liddle syndrome
excess; salt
tetraplegia
massive bleeding
premenstrual syndrome
neurally mediated syncope
hemorrhagic shock
calicectasis
death (sudden)
chronic uremia
aldosteronoma
adrenal insufficiencies
germ cell tumor
adenocarcinoma
tumor; wilms
abnormal; membranes
brain stem dysfunction
nephroangiosclerosis
congestion; venous
ovarian pregnancies
central diabetes insipidus
congenital hyperinsulinism
dyslipidemia
congenital hypothyroidism
RAO
high altitude pulmonary edema
heavy chain alpha
adrenal hyperplasia
malnutrition, protein-energy
failure liver
simple obesity
conversion; reaction
carcinoma hepatocellular
paroxysmal arrhythmia
men2b
hypertensive episode
anorexia nervosa
alkalosis respiratory
dissecting aortic aneurysm
uterine leiomyosarcoma
van der woude syndrome
growth failure
cataract
brain edema
systolic heart failure
pulmonary tuberculosis
placental site trophoblastic tumor
hypertensive renovascular disease
acidosis hyperchloraemic
compression; vein
adrenocortical adenoma
gestational trophoblastic disease
idiopathic intracranial hypertension
nephropathies
necrosis; renal; papillary
polyarteritis
retinal neovascularization
hyperchloremia

Advanced Search (alpha)

REN Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor REN gene

Summariesfor REN gene

Genomic Viewsfor REN gene

Proteinsfor REN gene

Protein Domains/Familiesfor REN gene

Gene Functionfor REN gene

Pathways & Interactionsfor REN gene

Drugs & Compoundsfor REN gene

Transcriptsfor REN gene

Expression for REN gene

Orthologsfor REN gene

Paralogsfor REN gene

Genomic Variantsfor REN gene

Disorders & Mutationsfor REN gene

Medical Newsfor REN gene

Publicationsfor REN gene

Search for REN gene

Genome Databases showing REN gene

Other Databases showing REN gene

Specialized Databases showing REN gene

Intellectual Propertyfor REN gene

Servicesfor REN gene

View Random Gene

Aliases &
Descriptions
for REN gene

Summaries
for REN gene

Genomic Views
for REN gene

Proteins
for REN gene

Protein Domains/
Families
for REN gene

Gene Function
for REN gene

Pathways & Interactions
for REN gene

Drugs & Compounds
for REN gene

Transcripts
for REN gene

Expression
for REN gene

Orthologs
for REN gene

Paralogs
for REN gene

Genomic Variants
for REN gene

Disorders & Mutations
for REN gene

Medical News
for REN gene

Publications
for REN gene

Intellectual Property
for REN gene

Services
for REN gene