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Aliases for RELL1 Gene

Aliases for RELL1 Gene

  • RELT-Like 1 2 3
  • Receptor Expressed In Lymphoid Tissues Like 1 3
  • RELT-Like Protein 1 3
  • Tmp_locus_29 3

External Ids for RELL1 Gene

Summaries for RELL1 Gene

GeneCards Summary for RELL1 Gene

RELL1 (RELT-Like 1) is a Protein Coding gene. An important paralog of this gene is RELT.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RELL1 Gene

Genomics for RELL1 Gene

Genomic Location for RELL1 Gene

Start:
37,588,059 bp from pter
End:
37,686,377 bp from pter
Size:
98,319 bases
Orientation:
Minus strand

Genomic View for RELL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RELL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RELL1 Gene

Regulatory Elements for RELL1 Gene

Proteins for RELL1 Gene

  • Protein details for RELL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IUW5-RELL1_HUMAN
    Recommended name:
    RELT-like protein 1
    Protein Accession:
    Q8IUW5
    Secondary Accessions:
    • Q8NBK1

    Protein attributes for RELL1 Gene

    Size:
    271 amino acids
    Molecular mass:
    29340 Da
    Quaternary structure:
    • Interacts with RELT, RELL2 and OXSR1.

neXtProt entry for RELL1 Gene

Proteomics data for RELL1 Gene at MOPED

Post-translational modifications for RELL1 Gene

Other Protein References for RELL1 Gene

No data available for DME Specific Peptides for RELL1 Gene

Domains for RELL1 Gene

Protein Domains for RELL1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RELL1_HUMAN
Family:
  • Belongs to the RELT family.:
    • Q8IUW5
genes like me logo Genes that share domains with RELL1: view

No data available for Gene Families for RELL1 Gene

Function for RELL1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RELL1 Gene

Localization for RELL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RELL1 Gene

Cell membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RELL1 Gene COMPARTMENTS Subcellular localization image for RELL1 gene
Compartment Confidence
plasma membrane 5
cytoskeleton 4
cytosol 3
extracellular 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for RELL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm --
GO:0005886 plasma membrane IDA --
GO:0015630 microtubule cytoskeleton IDA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RELL1: view

Pathways for RELL1 Gene

SuperPathways for RELL1 Gene

No Data Available

Interacting Proteins for RELL1 Gene

Gene Ontology (GO) - Biological Process for RELL1 Gene

None

No data available for Pathways by source for RELL1 Gene

Transcripts for RELL1 Gene

mRNA/cDNA for RELL1 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RELL1 Gene

RELT-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RELL1 Gene

No ASD Table

Relevant External Links for RELL1 Gene

GeneLoc Exon Structure for
RELL1
ECgene alternative splicing isoforms for
RELL1

Expression for RELL1 Gene

mRNA expression in normal human tissues for RELL1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RELL1 Gene

SOURCE GeneReport for Unigene cluster for RELL1 Gene Hs.283378

mRNA Expression by UniProt/SwissProt for RELL1 Gene

Q8IUW5-RELL1_HUMAN
Tissue specificity: Widely expressed. Expressed at highest levels in the placenta, skeletal muscle, spleen and testis.
genes like me logo Genes that share expressions with RELL1: view

Orthologs for RELL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RELL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RELL1 36
  • 99.31 (n)
  • 100 (a)
RELL1 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RELL1 36
  • 84.75 (n)
  • 85.98 (a)
RELL1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RELL1 36
  • 85.98 (n)
  • 88.93 (a)
RELL1 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rell1 36
  • 82.41 (n)
  • 88.19 (a)
Rell1 16
Rell1 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RELL1 37
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RELL1 37
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rell1 36
  • 82.41 (n)
  • 88.93 (a)
chicken
(Gallus gallus)
Aves RELL1 36
  • 67.95 (n)
  • 65.64 (a)
RELL1 37
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RELL1 37
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rell1 36
  • 61.25 (n)
  • 61.38 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC799556 36
  • 59.51 (n)
  • 56.59 (a)
RELL1 37
  • 42 (a)
OneToOne
Species with no ortholog for RELL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RELL1 Gene

ENSEMBL:
Gene Tree for RELL1 (if available)
TreeFam:
Gene Tree for RELL1 (if available)

Paralogs for RELL1 Gene

Paralogs for RELL1 Gene

Selected SIMAP similar genes for RELL1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RELL1: view

Variants for RELL1 Gene

Sequence variations from dbSNP and Humsavar for RELL1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs12142 -- 37,610,904(-) AATTC(C/T)TGTGT intron-variant, utr-variant-3-prime
rs919006 -- 37,674,319(+) CTGTA(A/C)AGAAT intron-variant
rs919007 -- 37,674,540(+) AGGCC(A/G)TACGA intron-variant
rs919008 -- 37,674,556(+) TAGAA(A/C)AAACT intron-variant
rs949998 -- 37,659,672(+) tTAGA(A/G)GCAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RELL1 Gene

Variant ID Type Subtype PubMed ID
nsv829909 CNV Loss 17160897
nsv878934 CNV Gain 21882294
nsv4303 CNV Insertion 18451855
esv2727432 CNV Deletion 23290073
esv2727433 CNV Deletion 23290073
esv2727434 CNV Deletion 23290073
esv2727435 CNV Deletion 23290073
nsv822535 CNV Loss 20364138
esv2727436 CNV Deletion 23290073
esv2727437 CNV Deletion 23290073

Relevant External Links for RELL1 Gene

HapMap Linkage Disequilibrium report
RELL1

Disorders for RELL1 Gene

Relevant External Links for RELL1

Genetic Association Database (GAD)
RELL1
Human Genome Epidemiology (HuGE) Navigator
RELL1
genes like me logo Genes that share disorders with RELL1: view

No data available for UniProtKB/Swiss-Prot for RELL1 Gene

Publications for RELL1 Gene

  1. Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1. (PMID: 16389068) Cusick J.K. … Shu H.-B. (Biochem. Biophys. Res. Commun. 2006) 2 3 4
  2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for RELL1 Gene

Sources for RELL1 Gene

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