REG3A Gene

Aliases
for REG3A gene

Previous GC identifers: GC02M079296 GC02M079119

Summaries
for REG3A gene

Genomic Views
for REG3A gene

RefSeq DNA sequence:

NC_000002.11  NC_018913.1  NT_022184.15  

SwitchGear Promoter luciferase reporter plasmid: REG3A promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat REG3A

REG3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M079384:  view genomic region     (about GC identifiers)

Proteins
for REG3A gene

2 PDB 3D structures from and Proteopedia for REG3A:

1UV0 (3D)        2GO0 (3D)    

Explore the universe of human proteins at neXtProt for REG3A: NX_Q06141

REG3A Protein expression data from MOPED and PaxDb:    About this image 

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Proteins (see all 3): REG3A OriGene Protein Over-expression Lysate (see all 4): REG3A OriGene Custom Protein Services for REG3A
	GenScript Custom Purified and Recombinant Proteins Services for REG3A
	Novus Biologicals REG3A Proteins Novus Biologicals REG3A Lysates
	Sino Biological Recombinant Protein for REG3A
	ProSpec Recombinant Protein for REG3A
	Uscn Proteins for REG3A

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for REG3A
	Browse OriGene Antibodies OriGene Custom Antibody Services for REG3A
	GenScript Custom Superior Antibodies Services for REG3A
	Novus Biologicals REG3A Antibodies
	Search for Antibodies for REG3A at Abcam
	Uscn Antibodies for REG3A
	ThermoFisher Antibody for REG3A

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for REG3A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for REG3A

Protein Domains /
Families
for REG3A gene

ProtoNet protein and cluster: Q06141

Function
for REG3A gene

miRNA Products:		OriGene 3'-UTR Clone (see all 3): REG3A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat REG3A
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate REG3A
		SwitchGear 3'UTR luciferase reporter plasmid: REG3A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for REG3A (see all 4) OriGene shRNA RFP: REG3A OriGene siRNA: REG3A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat REG3A

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for REG3A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for REG3A (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for REG3A (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): REG3A (NM_002580)
		Sino Biological Human cDNA Clone for REG3A
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for REG3A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REG3A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for REG3A
		Search LifeMap BioReagents cell lines for REG3A

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REG3A

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

(inferred from 1 allele) (MGI details for Reg3b)

Pathways & Interactions
for REG3A gene

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for REG3A gene

Transcripts
for REG3A gene

Expression
for REG3A gene

REG3A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGAGAAAT

3 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor Cells			Motor Neurons
	TestisSeminiferous TubulesSertoli cells			Testis
	Spinal CordSpinal Ventral Columns			Spinal Cord
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for REG3A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat REG3A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat REG3A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REG3A

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REG3A

Orthologs
for REG3A gene

Paralogs
for REG3A gene

Paralogs for REG3A gene

REG4²  REG3G²  CLEC19A²  REG1B²  REG1A²  

8 SIMAP similar genes for REG3A using alignment to 2 protein entries:     REG3A_HUMAN (see all proteins):

PAP    REG3G    REG1A    REG1B    CSPG3 variant protein    NCAN

REG4    MRC1L1

REG3A for paralogs           About GeneDecksing

Genomic Variants
for REG3A gene

10/125 NCBI SNPs in REG3A are shown (see all 125)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs777216431,2	F,	--	79119833(+)	GTTAAA/CGCCTC	3	--	int1		1		EA	120
rs124718521,2	C,F,H,	--	79119859(+)	AGTGTC/TCCAAT	3	--	int1		1		NA	6
rs562713581,2	C,F,	--	79120357(-)	CCTTGA/GGTTGT	3	--	int1		9		WA NA CSA	251
rs784653031,2		--	79120370(+)	ATATAT/CTATTT	3	--	int1		1		NA	120
rs22721091,2	C,F,H,	--	79121382(-)	TACTAC/TGGCTA	3	--	int1		16		EA NS NA	3576
rs1140069771,2	C,F,	--	79121514(+)	CTGACC/ACTCCA	3	--	int1		1		WA	118
rs22721081,2	C,F,H,	--	79121628(-)	GTTAAC/ATTGCA	3	--	int1		7		EA NS	2202
rs749766281,2	C,F,	--	79122037(+)	CTCTCC/TCATCC	3	--	int1 ut51		1		EA	120
rs75813531,2	A,H	--	79122125(+)	CCTGTG/ATCATG	3	--	int1 ut51		4		NS EA	420
rs728166551,2		--	79122198(+)	TGGTAC/TGGTTT	3	--	ut51		0	--	--	--	--

HapMap Linkage Disequilibrium report for REG3A (79384132 - 79386879 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for REG3A: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing REG3A

DNA2.0 Custom Variant and Variant Library Synthesis for REG3A

Disorders / Diseases
for REG3A gene

20/25 diseases for REG3A

10/20 Novoseek disease relationships for REG3A gene (see all 20)    About this table

Publications
for REG3A gene

PubMed articles for REG3A gene, integrated from 9 sources (see all 115): (articles sorted by number of sources associating them with REG3A)

Utopia: connect your pdf to the dynamic world of online information

1. Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene. (PubMed id 8188210)^{1, 2, 3, 9} Dusetti N.J....Iovanna J.L. (1994)
2. A novel gene (HIP) activated in human primary liver cancer. (PubMed id 1325291)^{1, 2, 9} Lasserre C.... Brechot C. (1992)
3. Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer. (PubMed id 8076648)^{1, 2, 9} Lasserre C.... Brechot C. (1994)
4. Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. (PubMed id 1469087)^{1, 2, 9} Orelle B.... Iovanna J.-L. (1992)
5. Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). (PubMed id 7679928)^{1, 2, 9} Itoh T. and Teraoka H. (1993)
6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
7. Pancreatitis-associated protein is related closely to neoplastic proliferative activity in patients with colorectal carcinoma. (PubMed id 19051257)^{1, 9} Cao G....Li F. (2009)
8. Pancreatitis-associated protein inhibits human pancreatic stellate cell MMP-1 and -2, TIMP-1 and -2 secretion and RECK expression. (PubMed id 19077460)^{1, 9} Li L....Graf R. (2009)
9. Discovery of a human peptide sequence signaling islet neogenesis. (PubMed id 19158046)^{1, 9} Levetan C.S....El-Hajj R.J. (2008)
10. Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters. (PubMed id 9151782)^{1, 9} Rafaeloff R....Vinik A.I. (1997)

External Searches for REG3A gene

Genome Databases showing REG3A gene

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Products
for REG3A gene