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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

REG1P Gene

pseudogene   GIFtS: 28
GCID: GC02M079363

regenerating islet-derived 1 pseudogene

(Previous names: rat regenerating islet-derived-like, human homolog (pancreatic...)
(Previous symbol: REGL)
 Explore 1 disease affiliated with
REG1P via our new
 Human Malady Compendium 
Biological research products
for REG1P
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Regenerating Islet-Derived 1 Pseudogene1 2
REGL1 2
RS1 2
Rat Regenerating Islet-Derived-Like, Human Homolog (Pancreatic Stone
Protein-Like, Pancreatic Thread Protein-Like)1
Regenerating Islet-Derived-Like, Pancreatic Stone Protein-Like, Pancreatic
Thread Protein-Like (Rat)1

External Ids:    HGNC: 99531   Entrez Gene: 59692   Ensembl: ENSG000002047877   
ORGUL members:         
NONCODE:n383660 n383662    

Export aliases for REG1P gene to outside databases

Previous GC identifers: GC02M079218 GC02M079097


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the REG1P gene promoter:
         Bach1   SREBP-1c   CUTL1   LCR-F1   SREBP-1b   Evi-1   AREB6   SREBP-1a   ZID   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat REG1P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p12   Ensembl cytogenetic band:  2p12   HGNC cytogenetic band: 2p12

REG1P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
REG1P gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M079363:  view genomic region     (about GC identifiers)

Start:
79,362,629 bp from pter      End:
79,365,553 bp from pter
Size:
2,925 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for REG1P

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB: --


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Animal Models:
   inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for REG1P 

miRNA
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for REG1P

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for REG1P
Search CenterWatch for drugs/clinical trials and news about REG1P 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Clusters for REG1P:

Regenerating islet-derived 1 pseudogene
Hs.584797  [show with all ESTs], Hs.716255  [show with all ESTs]
Unigene Representative Sequences: D56495, AK126561
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000444841(uc002soa.1) ENST00000377435(uc002sob.1) ENST00000447469
ENST00000414597 ENST00000443710 ENST00000450249 ENST00000434852

miRNA
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Inhib. RNA
Products:
     
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REG1P

Additional cDNA sequence: 

AK126561.1 NR_002714.1 

7 DOTS entries:

DT.308257  DT.101976696  DT.102824096  DT.100794212  DT.100794214  DT.120961909  DT.95255502 

20 AceView cDNA sequences:

D56495 AA363643 D56494 NM_006508 BG142191 AK126561 AA363642 CD622836 
CD622835 CD622827 AA363721 CD622824 CD622820 CD622831 CD622832 CD622814 
CD622828 CD622823 CD622818 CD622817 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

REG1P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCCCCCAT
REG1P Expression
About this image
Genevestigator expression for REG1P

SOURCE GeneReport for Unigene clusters: Hs.584797 Hs.716255
    SABiosciences Custom PCR Arrays for REG1P

Primer
Products:
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REG1P
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REG1P

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for REG1P (if available)
TreeFam Gene Tree for REG1P (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/98 NCBI SNPs in REG1P are shown (see all 98    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs104962131,2
C,F,H--79362154(+) TTTATT/GATTCA 1 -- ds500199Minor allele frequency- G:0.13NS EA PA EU CA WA NA 6306
rs729132751,2
C--79362244(+) TCAACG/ACTGTA 1 -- ds50011Minor allele frequency- A:0.50WA 2
rs1503733671,2
--79362322(+) CTTCCA/TCAGGT 1 -- ds50010--------
rs775826601,2
F--79362346(+) ACCTCT/CTTAGA 1 -- ds50011Minor allele frequency- C:0.04WA 118
rs1451389551,2
--79362403(+) TGACAC/GTGGGT 1 -- ds50010--------
rs1162824491,2
--79362582(+) CCCAAA/CTACCC 1 -- ds50010--------
rs75953681,2
C,F,H--79362619(+) ACAGAA/GGACAG 1 -- ds50017Minor allele frequency- G:0.09NS EA CSA WA NA 658
rs1490266821,2
--79362624(+) AGACAA/GCACTA 1 -- ds50010--------
rs1120804351,2
--79362625(+) GACAGC/TACTAT 1 -- ds50011Minor allele frequency- T:0.50CSA 2
rs1416637761,2
--79362745(+) ATGGAA/GAGAGA 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for REG1P (79362629 - 79365553 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for REG1P: --

SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

REG1P for disorders           About GeneDecksing

1 disease for REG1P:    About MalaCards
pancreatitis


Export disorders for REG1P gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for REG1P gene integrated from 9 sources:
(articles sorted by number of sources associating them with REG1P)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Human regeneration protein/lithostathine genes map to chromosome 2p12. (PubMed id 8333731)1, 3 Gharib B....Berge-lefranc J.L. (1993)
  2. Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III. (PubMed id 15556304)1 Nata K.... Okamoto H. (2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  5. Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12. (PubMed id 8549770)1 Miyashita H....Okamoto H. (1995)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 5969 HGNC: 9953 AceView: REGL Ensembl:ENSG00000204787 euGenes: HUgn5969
ECgene: REG1P H-InvDB: REG1P

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for REG1P Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for REG1P gene:
Search GeneIP for patents involving REG1P

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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