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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

REEP5 Gene

protein-coding   GIFtS: 51
GCID: GC05M112212

receptor accessory protein 5

(Previous name: chromosome 5 open reading frame 18 )
(Previous symbol: C5orf18)
 Explore 7 diseases affiliated with
REEP5 via our new
 Human Malady Compendium 
Biological research products
for REEP5
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Receptor Accessory Protein 51 2     YOP12
C5orf181 2 3 5     Deleted In Polyposis 12
DP11 2 3 5     Polyposis Coli Region Hypothetical Protein DP12
TB21 2 3     Receptor Expression Enhancing Protein 52
D5S3461 2 5     Receptor Expression-Enhancing Protein 52
Polyposis Locus Protein 12 3     Protein TB23
Chromosome 5 Open Reading Frame 181     

External Ids:    HGNC: 300771   Entrez Gene: 79052   Ensembl: ENSG000001296257   OMIM: 1252655   UniProtKB: Q007653   

Export aliases for REEP5 gene to outside databases

Previous GC identifers: GC05M112240 GC05M107391


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: REEP5_HUMAN, Q00765
Function: May promote functional cell surface expression of olfactory receptors

Gene Wiki entry for REEP5


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the REEP5 gene promoter:
         c-Fos   GR   AhR   AP-1   Fra-1   FosB   LCR-F1   Arnt   GR-alpha   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidREEP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for REEP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat REEP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q22-q23   Ensembl cytogenetic band:  5q22.2   HGNC cytogenetic band: 5q22-q23

REEP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
REEP5 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M112212:  view genomic region     (about GC identifiers)

Start:
112,212,081 bp from pter      End:
112,258,236 bp from pter
Size:
46,156 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: REEP5_HUMAN, Q00765 (See protein sequence)
Recommended Name: Receptor expression-enhancing protein 5  
Size: 189 amino acids; 21493 Da
Subunit: Interacts with ATL1 (By similarity). Interacts with ATL2
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAA60136.1; Type=Erroneous initiation; Sequence=AAA66351.1; Type=Erroneous initiation;
Sequence=AAH65926.1; Type=Erroneous initiation;
Secondary accessions: D3DT04 Q04198 Q5QGT0 Q9BWH9

Explore the universe of human proteins at neXtProt for REEP5: NX_Q00765

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q00765

  • REEP5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005660.4  
    ENSEMBL proteins: 
     ENSP00000368959   ENSP00000425901   ENSP00000421305   ENSP00000261482   ENSP00000421881  
     ENSP00000442940  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: REEP5
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    Novus Biologicals REEP5 Proteins
    Novus Biologicals REEP5 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for REEP5

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane NAS--


    REEP5 for ontologies           About GeneDecksing



    REEP5 Antibody Products: 
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    Uscn Antibodies for REEP5
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    Uscn ELISAs and CLIAs for REEP5


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    REEP5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004345 TB2_DP1_HVA22

    Graphical View of Domain Structure for InterPro Entry Q00765

    ProtoNet protein and cluster: Q00765

    1 Blocks protein family: IPB004345 TB2/DP1 and HVA22 related proteins

    UniProtKB/Swiss-Prot: REEP5_HUMAN, Q00765
    Similarity: Belongs to the DP1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: REEP5_HUMAN, Q00765
    Function: May promote functional cell surface expression of olfactory receptors

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat REEP5
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate REEP5 (see all 27):
    hsa-miR-323-3p hsa-miR-3685 hsa-miR-217 hsa-miR-548j hsa-miR-548i hsa-miR-1205 hsa-miR-3613-3p hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidREEP5 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for REEP5 (see all 7)
    OriGene shRNA RFP: REEP5
    OriGene siRNA: REEP5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat REEP5

    Gene Editing
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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for REEP5 (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REEP5 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP5

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0004872receptor activity ----
    GO:0005515protein binding IPI16762630


    REEP5 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Reep5):
     normal 

    REEP5 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for REEP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/48 Interacting proteins for REEP5 (Q007651, 2, 3 ENSP000003689594) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LETMD1Q6P1Q01, 3, ENSP000002620554EBI-1549827,EBI-1549822 I2D: score=1 STRING: ENSP00000262055
    NUDT3O959892, 3MINT-8264967 I2D: score=2 
    RGS2P412202, 3MINT-8268922 I2D: score=2 
    E2F6O754612, 3, ENSP000003709364MINT-14072 I2D: score=1 STRING: ENSP00000370936
    RABAC1Q9UI142, 3, ENSP000002220084MINT-8267808 I2D: score=4 STRING: ENSP00000222008
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--


    REEP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for REEP5
    Search CenterWatch for drugs/clinical trials and news about REEP5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for REEP5 gene: 
    NM_005669.4  

    Unigene Cluster for REEP5:

    Receptor accessory protein 5
    Hs.429608  [show with all ESTs]
    Unigene Representative Sequence: NM_005669
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379638(uc011cvw.1 uc003kqe.1 uc011cvx.1 uc011cvy.1 uc011cvz.1)
    ENST00000497856 ENST00000513339 ENST00000511865 ENST00000261482 ENST00000474542
    ENST00000504247 ENST00000545426

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: REEP5
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat REEP5
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate REEP5 (see all 27):
    hsa-miR-323-3p hsa-miR-3685 hsa-miR-217 hsa-miR-548j hsa-miR-548i hsa-miR-1205 hsa-miR-3613-3p hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidREEP5 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for REEP5 (see all 7)
    OriGene shRNA RFP: REEP5
    OriGene siRNA: REEP5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat REEP5
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for REEP5 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for REEP5 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: REEP5 (NM_005669)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REEP5 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat REEP5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REEP5

    Additional cDNA sequence: 

    AK294496.1 AK295436.1 AK298268.1 AK299902.1 AK300048.1 AK310729.1 AK312522.1 AY562243.1 
    BC000232.1 BC065926.1 BX648005.1 M74090.1 

    16 DOTS entries:

    DT.91773366  DT.40258334  DT.101958294  DT.100823802  DT.100823804  DT.100733913  DT.100823803  DT.120809624 
    DT.120809674  DT.120809687  DT.120809754  DT.120809762  DT.120809790  DT.91773368  DT.91773377  DT.99927206 

    24/498 AceView cDNA sequences (see all 498):

    CA943668 BQ002353 AA236841 N72728 BQ012560 AW466954 AA385860 CR615731 
    BU580935 AW611887 AI431658 BQ574275 BQ011856 BQ013208 AA878281 CA306729 
    AL557589 CR603989 AW466998 AA280788 BP870922 AI434416 AV709572 AA262090 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for REEP5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b
    SP1:              -     -     -                 -                           
    SP2:              -     -     -           -     -                           
    SP3:                    -     -                 -                           
    SP4:                                                                        
    SP5:                                            -                           


    ECgene alternative splicing isoforms for REEP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    REEP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See REEP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for REEP5

    SOURCE GeneReport for Unigene cluster: Hs.429608
        SABiosciences Custom PCR Arrays for REEP5
    Primer
    Products:
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REEP5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for REEP5 gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves REEP51 receptor accessory protein 5 80.78(n)
    85.19(a)
      770021  NM_001252077.1  NP_001239006.1 
    lizard
    (Anolis carolinensis)
    Reptilia REEP56
    --
    81(a)
    1 ↔ 1
    GL343193.1(7017239-7038666)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC041760.12   -- 75.43(n)    BC041760.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC059545.12   -- 76.01(n)   337237  BC059545.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG83311 CG8331 58.8(n)
    52.78(a)
      36569  NM_137092.3  NP_610936.2 
    worm
    (Caenorhabditis elegans)
    Secernentea yop-11 Protein YOP-1 53.33(n)
    47.88(a)
      171835  NM_058632.3  NP_491033.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATHVA22E6
    ATHVA22D6
    (see all 11)
    HVA22-like protein d
    (see all 11)
    32(a)
    28(a)
    (see all 11)
    possible ortholog
    possible ortholog
    (see all 11)
    5(20633193-20634552)
    4(12827936-12829243)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 16)
    HVA22, putative, expressed
    (see all 16)
    9(a)
    5(a)
    (see all 16)
    possible ortholog
    possible ortholog
    (see all 16)
    10(5357503-5363472)
    1(30362018-30369168)


    ENSEMBL Gene Tree for REEP5 (if available)
    TreeFam Gene Tree for REEP5 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for REEP5 gene
    REEP12  REEP42  REEP32  REEP62  REEP22  
    4 SIMAP similar genes for REEP5 using alignment to 6 protein entries:     REEP5_HUMAN (see all proteins):
    REEP6    REEP1    REEP4    REEP2

    REEP5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/603 NCBI SNPs in REEP5 are shown (see all 603    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1500730311,2
    --112229331(+) TGATGA/GAAAGG 1 -- int10--------
    rs1931746691,2
    --112229366(+) AGTCTC/TGCTAC 1 -- int10--------
    rs1136584451,2
    C,--112229367(+) GTCTCG/ACTACA 1 -- int12Minor allele frequency- A:0.04NA 122
    rs1453804521,2
    --112229402(+) GAATGC/TGCAAT 1 -- int10--------
    rs1389630241,2
    --112229403(+) AATGTC/GCAATC 1 -- int10--------
    rs1457308031,2
    --112229433(+) CCTTCG/TGCACA 1 -- int10--------
    rs1478033051,2
    --112229445(+) ACACAA/GTGGTA 1 -- int10--------
    rs4340901,2
    C,F,O,A,--112229523(-) ACTACT/CTGCAC 1 -- int115Minor allele frequency- C:0.31NA EA WA CSA 872
    rs1162113021,2
    --112229531(+) AGTTCG/AATGTT 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1474335961,2
    C,--112229637(+) CCTTG-/GTT   
       TTTTT
    GAGAT
    1 -- int10--------

    HapMap Linkage Disequilibrium report for REEP5 (112212081 - 112258236 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for REEP5
         1 CNV: 7468
         1 Indel: 69184

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing REEP5
    DNA2.0 Custom Variant and Variant Library Synthesis for REEP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    REEP5 for disorders           About GeneDecksing

    OMIM gene information: 125265    OMIM disorders: --

    7 diseases for REEP5:    About MalaCards
    polyposis    muir-torre syndrome    adenomatous polyposis coli    familial adenomatous polyposis
    adhd    colorectal cancer    malaria

    4 diseases from the University of Copenhagen DISEASES database for REEP5:
    Lynch syndrome     Colorectal cancer     Familial adenomatous polyposis     Carcinoma
    Human Genome Epidemiology (HuGE) Navigator: REEP5 (3 documents)

    Export disorders for REEP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for REEP5 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with REEP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RTP family members induce functional expression of mammalian odorant receptors. (PubMed id 15550249)1, 2, 3 Saito H....Matsunami H. (2004)
    2. Inherited ACTH insensitivity illuminates the mechanisms of ACTH action. (PubMed id 16271481)1, 3 Clark A.J....Huebner A. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Identification of FAP locus genes from chromosome 5q21. (PubMed id 1651562)1, 2 Kinzler K.W.... Nakamura Y. (1991)
    5. Identification of deletion mutations and three new genes at the familial polyposis locus. (PubMed id 1678319)1, 2 Joslyn G.... White R. (1991)
    6. Association of APC and REEP5 gene polymorphisms with m ajor depression disorder and treatment response to antidepressants in a Han Chin ese population. (PubMed id 22795047)1 Yang Z....Li T. (2012)
    7. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)1 Shamay M....Hayward S.D. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7905 HGNC: 30077 AceView: C5orf18 Ensembl:ENSG00000129625 euGenes: HUgn7905
    ECgene: REEP5 H-InvDB: REEP5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for REEP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for REEP5 gene:
    Search GeneIP for patents involving REEP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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