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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

REEP3 Gene

protein-coding   GIFtS: 52
GCID: GC10P065281

Receptor Accessory Protein 3

(Previous name: chromosome 10 open reading frame 74)
(Previous symbol: C10orf74)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Receptor Accessory Protein 31 2
C10orf741 2 3 5
Chromosome 10 Open Reading Frame 741
Receptor Expression Enhancing Protein 32
Receptor Expression-Enhancing Protein 32

External Ids:    HGNC: 237111   Entrez Gene: 2210352   Ensembl: ENSG000001654767   OMIM: 6093485   UniProtKB: Q6NUK43   

Export aliases for REEP3 gene to outside databases

Previous GC identifers: GC10P064952 GC10P059317


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for REEP3 Gene: 
REEP3 (receptor accessory protein 3) is a protein-coding gene. Diseases associated with REEP3 include alzheimer's disease, and arthritis. An important paralog of this gene is REEP1.

UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4
Function: May enhance the cell surface expression of odorant receptors (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the REEP3 gene promoter:
         Max1   ER-alpha   HTF   AP-2gamma   FOXJ2 (long isoform)   Sox9   AP-2beta   AP-2alpha   c-Myc   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidREEP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for REEP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat REEP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.3   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q21.3

REEP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
REEP3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P065281:  view genomic region     (about GC identifiers)

Start:
65,281,123 bp from pter      End:
65,384,883 bp from pter
Size:
103,761 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4 (See protein sequence)
Recommended Name: Receptor expression-enhancing protein 3  
Size: 255 amino acids; 29264 Da
Subunit: Interacts with odorant receptor proteins (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=AAH10040.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q5JQR5 Q5QGT2 Q6PEW8 Q6PJY4
Alternative splicing: 2 isoforms:  Q6NUK4-1   Q6NUK4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for REEP3: NX_Q6NUK4

Explore proteomics data for REEP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6NUK4

  • REEP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    REEP3 Protein Expression
    REFSEQ proteins: NP_001001330.1  
    ENSEMBL proteins: 
     ENSP00000298249   ENSP00000362863  

    Human Recombinant Protein Products for REEP3: 
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    OriGene MassSpec for REEP3 
    OriGene Custom Protein Services for REEP3
    GenScript Custom Purified and Recombinant Proteins Services for REEP3
    Novus Biologicals REEP3 Protein
    Novus Biologicals REEP3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for REEP3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005874microtubule IEA--
    GO:0016021integral to membrane IEA--

    REEP3 for ontologies           About GeneDecksing



    REEP3 Antibody Products: 
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    Assay Products for REEP3: 
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    Cloud-Clone Corp. ELISAs for REEP3 
    Cloud-Clone Corp. CLIAs for REEP3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    REEP: Receptor accessory proteins

    1 InterPro protein domain:
     IPR004345 TB2_DP1_HVA22

    Graphical View of Domain Structure for InterPro Entry Q6NUK4

    ProtoNet protein and cluster: Q6NUK4

    1 Blocks protein domain: IPB004345 TB2/DP1 and HVA22 related proteins

    UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4
    Similarity: Belongs to the DP1 family


    REEP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: REEP3_HUMAN, Q6NUK4
    Function: May enhance the cell surface expression of odorant receptors (By similarity)

    Animal Models:

       inGenious Targeting Laboratory - Custom generated mouse model solutions for REEP3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for REEP3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for REEP3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for REEP3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat REEP3
    8/95 QIAGEN miScript miRNA Assays for microRNAs that regulate REEP3 (see all 95):
    hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidREEP3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for REEP3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat REEP3

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of REEP3

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for REEP3 (see all 7)
    OriGene ORF clones in mouse, rat for REEP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: REEP3 (NM_001001330)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for REEP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REEP3
    Sirion Biotech Customized lentivirus for stable overexpression of REEP3 
                         Customized lentivirus expression plasmids for stable overexpression of REEP3 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for REEP3
    Search LifeMap BioReagents cell lines for REEP3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for REEP3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for REEP3 (Q6NUK42, 3 ENSP000003628634) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3976629 I2D: score=1 
    ARL6IP5O759153I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006998nuclear envelope organization IMP--
    GO:0007067mitosis IEA--
    GO:0007084mitotic nuclear envelope reassembly IMP--
    GO:0051301cell division IEA--

    REEP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for REEP3

    Search CenterWatch for drugs/clinical trials and news about REEP3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for REEP3 gene: 
    NM_001001330.2  

    Unigene Cluster for REEP3:

    Receptor accessory protein 3
    Hs.499833  [show with all ESTs]
    Unigene Representative Sequence: NM_001001330
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298249 ENST00000373758(uc009xpl.2 uc001jmt.3)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat REEP3
    8/95 QIAGEN miScript miRNA Assays for microRNAs that regulate REEP3 (see all 95):
    hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidREEP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for REEP3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat REEP3
    Clone
    Products:
         
    OriGene clones in human, mouse for REEP3 (see all 7)
    OriGene ORF clones in mouse, rat for REEP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: REEP3 (NM_001001330)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for REEP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REEP3
    Sirion Biotech Customized lentivirus for stable overexpression of REEP3 
                         Customized lentivirus expression plasmids for stable overexpression of REEP3 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for REEP3
    OriGene qSTAR qPCR primer pairs in human, mouse for REEP3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat REEP3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat REEP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REEP3

    Additional mRNA sequence: 

    AK289976.1 AY562241.1 BC010040.2 BC018658.1 BC038724.1 BC057832.1 BC068557.1 CR936686.1 

    11 DOTS entries:

    DT.415955  DT.80102037  DT.91686888  DT.95164555  DT.95164557  DT.97838862  DT.100021448  DT.95164559 
    DT.121260033  DT.40250675  DT.91765865 

    24/154 AceView cDNA sequences (see all 154):

    BI826741 CA455063 AI079315 BM841117 CA422715 BQ225487 AA100609 BX494303 
    BX280876 BC057832 AI192275 AL118571 BM761268 AA730643 AA620591 AI922029 
    W56228 BU197986 BC010040 W31882 AA548384 BM830660 AI499277 AW593082 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    REEP3 expression in normal human tissues (normalized intensities)      REEP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTAACATT
    REEP3 Expression
    About this image


    REEP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter

    See REEP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for REEP3

    SOURCE GeneReport for Unigene cluster: Hs.499833
        SABiosciences Custom PCR Arrays for REEP3
    Primer
    Products:
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat REEP3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for REEP3 gene from 8/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Reep31 , 5 receptor accessory protein 31, 5 84.38(n)1
    92.52(a)1
      10 (34.83 cM)5
    281931  NM_178606.51  NP_848721.11 
     670091895 
    chicken
    (Gallus gallus)
    Aves REEP31 receptor accessory protein 3 79.22(n)
    83.92(a)
      423654  NM_001199532.1  NP_001186461.1 
    lizard
    (Anolis carolinensis)
    Reptilia REEP36
    Uncharacterized protein
    69(a)
    1 ↔ 1
    GL343204.1(2295507-2333207)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC687642 hypothetical protein MGC68764 74.05(n)    BC063730.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc555292 hypothetical protein MGC55529 75.1(n)   393130  BC045373.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG116976
    CG55396
    (see all 3)
    --
    15(a)
    15(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    X(11466740-11467673)
    2R(19692334-19693411)
    worm
    (Caenorhabditis elegans)
    Secernentea T19C3.46
    T03F6.66
    (see all 3)
    Protein T03F6.6
    (see all 3)
    36(a)
    15(a)
    (see all 3)
    1 ↔ many
    possible ortholog
    (see all 3)
    III(618248-620212)
    III(13378441-13380352)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YOP16
    Membrane protein that interacts with Yip1p to medi...
    18(a)
    1 → many
    XVI(623527-624202)


    ENSEMBL Gene Tree for REEP3 (if available)
    TreeFam Gene Tree for REEP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for REEP3 gene
    REEP12  REEP42  REEP52  REEP62  REEP22  
    3 SIMAP similar genes for REEP3 using alignment to 2 protein entries:     REEP3_HUMAN (see all proteins):
    REEP1    REEP4    REEP2

    REEP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1734 SNPs in REEP3 are shown (see all 1734)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1834303921,2
    --65279305(+) ATTCAA/GTACAT 1 -- us2k10--------
    rs1882877541,2
    --65279311(+) TACATA/TAGACA 1 -- us2k10--------
    rs1922353371,2
    --65279347(+) AGAAAC/TAGAAA 1 -- us2k10--------
    rs763786001,2
    F--65279420(+) AGGATG/ATCTTC 1 -- us2k12Minor allele frequency- A:0.02WA NA 238
    rs1829333351,2
    --65279482(+) CAAAGC/TGTTAA 1 -- us2k10--------
    rs1412215761,2
    C--65279760(+) ATTCAC/GAGTTA 1 -- us2k10--------
    rs797613981,2
    --65279868(+) TTGTTA/TCTTAA 1 -- us2k10--------
    rs70710911,2
    C,F--65279908(+) GAGAAC/GTGAAA 1 -- us2k12Minor allele frequency- G:0.11WA NA 238
    rs1876351971,2
    --65280163(+) TATTCA/TTCGCA 1 -- us2k10--------
    rs108221791,2
    C,F,A,H--65280164(+) ATTCTC/TCGCAC 1 -- us2k124Minor allele frequency- T:0.43NS EA NA WA 2760

    HapMap Linkage Disequilibrium report for REEP3 (65281123 - 65384883 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for REEP3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2737640CNV Deletion23290073
    esv2334532CNV Deletion18987734
    esv272741CNV Insertion20981092
    nsv895571CNV Loss21882294
    esv22964CNV Loss19812545

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing REEP3
    DNA2.0 Custom Variant and Variant Library Synthesis for REEP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609348    OMIM disorders: --

    2 diseases for REEP3:    About MalaCards
    alzheimer's disease    arthritis


    REEP3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): REEP3
    Human Genome Epidemiology (HuGE) Navigator: REEP3 (3 documents)

    Export disorders for REEP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for REEP3 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with REEP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RTP family members induce functional expression of mammalian odorant receptors. (PubMed id 15550249)1, 2, 3 Saito H....Matsunami H. (2004)
    2. Genome-wide association analysis of juvenile idiopathi c arthritis identifies a new susceptibility locus at chromosomal region 3q13. (PubMed id 22354554)1, 4 Thompson S.D....Glass D.N. (2012)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PubMed id 18940312)1, 4 Yuan X....Mooser V. (2008)
    5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    6. Inherited ACTH insensitivity illuminates the mechanisms of ACTH action. (PubMed id 16271481)1, 3 Clark A.J....Huebner A. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    9. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism. (PubMed id 17290275)1, 9 Castermans D....Devriendt K. (2007)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221035 HGNC: 23711 AceView: C10orf74 Ensembl:ENSG00000165476 euGenes: HUgn221035
    ECgene: REEP3 H-InvDB: REEP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for REEP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for REEP3 gene:
    Search GeneIP for patents involving REEP3

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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