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REEP3 Gene

protein-coding   GIFtS: 54
GCID: GC10P065281

Receptor Accessory Protein 3

(Previous name: chromosome 10 open reading frame 74)
(Previous symbol: C10orf74)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Receptor Accessory Protein 31 2
C10orf741 2 3 5
Chromosome 10 Open Reading Frame 741
Receptor Expression Enhancing Protein 32
Receptor Expression-Enhancing Protein 32

External Ids:    HGNC: 237111   Entrez Gene: 2210352   Ensembl: ENSG000001654767   OMIM: 6093485   UniProtKB: Q6NUK43   

Export aliases for REEP3 gene to outside databases

Previous GC identifers: GC10P064952 GC10P059317


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for REEP3 Gene:
REEP3 (receptor accessory protein 3) is a protein-coding gene. An important paralog of this gene is REEP4.

UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4
Function: Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by
sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the
endoplasmic reticulum membrane from metaphase chromosomes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the REEP3 gene promoter:
         Max1   ER-alpha   HTF   AP-2gamma   FOXJ2 (long isoform)   Sox9   AP-2beta   AP-2alpha   c-Myc   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidREEP3 promoter sequence
   Search Chromatin IP Primers for REEP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat REEP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.3   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q21.3

REEP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
REEP3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P065281:  view genomic region     (about GC identifiers)

Start:
65,281,123 bp from pter      End:
65,384,883 bp from pter
Size:
103,761 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4 (See protein sequence)
Recommended Name: Receptor expression-enhancing protein 3  
Size: 255 amino acids; 29264 Da
Sequence caution: Sequence=AAH10040.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q5JQR5 Q5QGT2 Q6PEW8 Q6PJY4
Alternative splicing: 2 isoforms:  Q6NUK4-1   Q6NUK4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for REEP3: NX_Q6NUK4

Explore proteomics data for REEP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys99, Lys111
  • Modification sites at PhosphoSitePlus

  • See REEP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001001330.1  
    ENSEMBL proteins: 
     ENSP00000298249   ENSP00000362863  

    REEP3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for REEP3

     
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    Search eBioscience for ELISAs for REEP3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    REEP: Receptor accessory proteins

    1 InterPro protein domain:
     IPR004345 TB2_DP1_HVA22

    Graphical View of Domain Structure for InterPro Entry Q6NUK4

    ProtoNet protein and cluster: Q6NUK4

    1 Blocks protein domain: IPB004345 TB2/DP1 and HVA22 related proteins

    UniProtKB/Swiss-Prot: REEP3_HUMAN, Q6NUK4
    Similarity: Belongs to the DP1 family


    Find genes that share domains with REEP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: REEP3_HUMAN, Q6NUK4
    Function: Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by
    sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the
    endoplasmic reticulum membrane from metaphase chromosomes

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for REEP3
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    miRNA
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    miRTarBase miRNAs that target REEP3:
    hsa-mir-96-5p (MIRT027898), hsa-mir-34a-5p (MIRT025553), hsa-mir-93-5p (MIRT028114), hsa-mir-374b-5p (MIRT016063), hsa-mir-590-3p (MIRT016224), hsa-mir-375 (MIRT020016), hsa-mir-335-5p (MIRT018792), hsa-mir-26b-5p (MIRT030093)

    Block miRNA regulation of human, mouse, rat REEP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate REEP3 (see all 95):
    hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidREEP3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat REEP3

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    REEP3_HUMAN, Q6NUK4: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus2
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005874microtubule IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with REEP3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for REEP3
    Interactions:

        Search GeneGlobe Interaction Network for REEP3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for REEP3 (Q6NUK42, 3 ENSP000003628634) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3976629 I2D: score=1 
    ARL6IP5O759153I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    YIF1AENSP000003660984STRING: ENSP00000366098
    YIF1BENSP000003434354STRING: ENSP00000343435
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006998nuclear envelope organization IMP--
    GO:0007067mitosis IEA--
    GO:0007084mitotic nuclear envelope reassembly IMP--

    Find genes that share ontologies with REEP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for REEP3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for REEP3 gene: 
    NM_001001330.2  

    Unigene Cluster for REEP3:

    Receptor accessory protein 3
    Hs.499833  [show with all ESTs]
    Unigene Representative Sequence: NM_001001330
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000298249 ENST00000373758(uc009xpl.2 uc001jmt.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat REEP3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate REEP3 (see all 95):
    hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidREEP3 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat REEP3
    Primer
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    OriGene qPCR primer pairs and template standards for REEP3
    OriGene qSTAR qPCR primer pairs in human, mouse for REEP3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat REEP3
      QuantiTect SYBR Green Assays in human, mouse, rat REEP3
      QuantiFast Probe-based Assays in human, mouse, rat REEP3

    Additional mRNA sequence: 

    AK289976.1 AY562241.1 BC010040.2 BC018658.1 BC038724.1 BC057832.1 BC068557.1 CR936686.1 

    11 DOTS entries:

    DT.415955  DT.80102037  DT.91686888  DT.95164555  DT.95164557  DT.97838862  DT.100021448  DT.95164559 
    DT.121260033  DT.40250675  DT.91765865 

    Selected AceView cDNA sequences (see all 154):

    W56228 BQ225487 AA548384 CA455063 AA620591 BM761268 CA422715 BI826741 
    AI922029 AA100609 AI499277 BU197986 BM841117 W31882 BC010040 AI192275 
    AL118571 BC057832 AI079315 BM830660 BX280876 BX494303 AA730643 AI050673 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    REEP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTAACATT
    REEP3 Expression
    About this image


    REEP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter
    REEP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    REEP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.499833
        Custom PCR Arrays for REEP3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for REEP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for REEP3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Reep31 , 5 receptor accessory protein 31, 5 84.38(n)1
    92.52(a)1
      10 (34.83 cM)5
    281931  NM_178606.51  NP_848721.11 
     670091895 
    chicken
    (Gallus gallus)
    Aves REEP31 receptor accessory protein 3 79.22(n)
    83.92(a)
      423654  NM_001199532.1  NP_001186461.1 
    lizard
    (Anolis carolinensis)
    Reptilia REEP36
    receptor accessory protein 3
    69(a)
    1 ↔ 1
    GL343204.1(2295507-2333207)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC687642 hypothetical protein MGC68764 74.05(n)    BC063730.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc555292 hypothetical protein MGC55529 75.1(n)   393130  BC045373.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG55396
    CG426786
    --
    16(a)
    14(a)
    many ↔ many
    many ↔ many
    2R(19692334-19693411)
    2R(18812613-18819567)
    worm
    (Caenorhabditis elegans)
    Secernentea T19C3.46
    Protein T19C3.4 (T19C3.4) mRNA, complete cds
    37(a)
    1 → many
    III(618248-620212) WBGene00020562
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YOP16
    Membrane protein that interacts with Yip1p to medi...
    20(a)
    1 → many
    XVI(623527-624202) YPR028W


    ENSEMBL Gene Tree for REEP3 (if available)
    TreeFam Gene Tree for REEP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for REEP3 gene
    REEP42  REEP12  REEP52  REEP62  REEP22  
    3 SIMAP similar genes for REEP3 using alignment to 2 protein entries:     REEP3_HUMAN (see all proteins):
    REEP1    REEP4    REEP2

    Find genes that share paralogs with REEP3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for REEP3 (see all 1734)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1834303921,2
    --65279305(+) ATTCAA/GTACAT 1 -- us2k10--------
    rs1882877541,2
    --65279311(+) TACATA/TAGACA 1 -- us2k10--------
    rs1922353371,2
    --65279347(+) AGAAAC/TAGAAA 1 -- us2k10--------
    rs763786001,2
    F--65279420(+) AGGATG/ATCTTC 1 -- us2k12Minor allele frequency- A:0.02WA NA 238
    rs1829333351,2
    --65279482(+) CAAAGC/TGTTAA 1 -- us2k10--------
    rs1412215761,2
    C--65279760(+) ATTCAC/GAGTTA 1 -- us2k10--------
    rs797613981,2
    --65279868(+) TTGTTA/TCTTAA 1 -- us2k10--------
    rs70710911,2
    C,F--65279908(+) GAGAAC/GTGAAA 1 -- us2k12Minor allele frequency- G:0.11WA NA 238
    rs1876351971,2
    --65280163(+) TATTCA/TTCGCA 1 -- us2k10--------
    rs108221791,2
    C,F,A,H--65280164(+) ATTCTC/TCGCAC 1 -- us2k124Minor allele frequency- T:0.43NS EA NA WA 2760

    HapMap Linkage Disequilibrium report for REEP3 (65281123 - 65384883 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for REEP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2737640CNV Deletion23290073
    esv2334532CNV Deletion18987734
    esv272741CNV Insertion20981092
    nsv895571CNV Loss21882294
    esv22964CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing REEP3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609348    OMIM disorders: --


    Find genes that share disorders with REEP3           About GenesLikeMe

    Genetic Association Database (GAD): REEP3
    Human Genome Epidemiology (HuGE) Navigator: REEP3 (3 documents)

    Export disorders for REEP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for REEP3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with REEP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RTP family members induce functional expression of mammalian odorant receptors. (PubMed id 15550249)1, 2, 3 Saito H.... Matsunami H. (Cell 2004)
    2. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism. (PubMed id 17290275)1, 2, 9 Castermans D....Devriendt K. (Eur. J. Hum. Genet. 2007)
    3. REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture. (PubMed id 23911198)1, 2 Schlaitz A.L.... Heald R. (Dev. Cell 2013)
    4. Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. (PubMed id 22354554)1, 4 Thompson S.D....Glass D.N. (Arthritis Rheum. 2012)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    6. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PubMed id 18940312)1, 4 Yuan X....Mooser V. (Am. J. Hum. Genet. 2008)
    7. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    8. Inherited ACTH insensitivity illuminates the mechanisms of ACTH action. (PubMed id 16271481)1, 3 Clark A.J....Huebner A. (Trends Endocrinol. Metab. 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 221035 HGNC: 23711 AceView: C10orf74 Ensembl:ENSG00000165476 euGenes: HUgn221035
    ECgene: REEP3 H-InvDB: REEP3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for REEP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for REEP3 gene:
    Search GeneIP for patents involving REEP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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