RECQL5 Gene
protein-coding GIFtS: 57
GCID: GC17M073622
|
|
RecQ protein-like 5
| |
Aliases
for RECQL5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RecQ Protein-Like 51 2 3 | | FLJ906031 | | RECQ52 3 5 | | ATP-Dependent DNA Helicase Q52 | | RecQ51 3 | | EC 3.6.4.123 | | DNA Helicase, RecQ-Like Type 52 3 | | EC 3.6.18 |
Export aliases for RECQL5 gene to outside databasesPrevious GC identifers: GC17M073593 GC17M076648 GC17M074087 GC17M074220 GC17M071134 GC17M069046 |
Summaries
for RECQL5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RECQL5:
The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein alsoprevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Jul 2011)
UniProtKB/Swiss-Prot: RECQ5_HUMAN, O94762Function: May have an important role in DNA metabolism
Gene Wiki entry for RECQL5
|
Genomic Views
for RECQL5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RECQL5 gene promoter:
CREB AML1a HTF POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2
Other transcription factors
Search SABiosciences Chromatin IP Primers for RECQL5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RECQL5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25RECQL5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M073622: view genomic region
(about GC identifiers)
Start:
|
73,622,925 bp from pter |
End:
|
73,663,269 bp from pter |
Size:
|
40,345 bases |
Orientation:
|
minus strand |
|
Proteins
for RECQL5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RECQ5_HUMAN, O94762 (See
protein sequence)Recommended Name: ATP-dependent DNA helicase Q5 Size: 991 amino acids; 108858 Da
Subunit: Interacts with TOP3A and TOP3B
Subcellular location: Isoform Beta: Nucleus, nucleoplasm
Subcellular location: Isoform Alpha: Cytoplasm
Subcellular location: Isoform Gamma: Cytoplasm
Secondary accessions: Q9H0B1 Q9P1W7 Q9UNC8Alternative splicing: 3 isoforms: O94762-1 O94762-2 O94762-3 Explore the universe of human proteins at neXtProt for RECQL5: NX_O94762
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O94762
4 DME Specific Peptides for RECQL5 (O94762)
RECQL5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001003715.1 NP_001003716.1 NP_004250.4
ENSEMBL proteins: ENSP00000394820 ENSP00000317636 ENSP00000462678 ENSP00000462291 ENSP00000463701 ENSP00000463099 ENSP00000462077 ENSP00000414933 ENSP00000341983 ENSP00000462248 ENSP00000462547
Human Recombinant Protein Products for RECQL5:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
RECQL5 for ontologies About GeneDecksing
RECQL5 Antibody Products:
Assay Products for RECQL5: |
Protein
Domains /
Families
for RECQL5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RECQL5 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry O94762ProtoNet protein and cluster: O94762 1 Blocks protein family: IPB002464 ATP-dependent helicase
UniProtKB/Swiss-Prot: RECQ5_HUMAN, O94762Similarity: Belongs to the helicase family. RecQ subfamilySimilarity: Contains 1 helicase ATP-binding domainSimilarity: Contains 1 helicase C-terminal domain |
Function
for RECQL5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RECQ5_HUMAN, O94762Function: May have an important role in DNA metabolismCatalytic activity: ATP + H(2)O = ADP + phosphate Genatlas biochemistry entry for RECQL5:DNA helicase ATP dependent,homologous to E coli RecQ,ubiquitously expressed,upregulated at the G2-M stage of the cellcycle,RecQl family
Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RECQL5 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for RECQL5:
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Recql5):
RECQL5 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Recql5tm1.1Glu for RECQL5
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RECQL5 (NM_001003716) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RECQL5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RECQL5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RECQL5 |
|
Pathways & Interactions
for RECQL5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell Cycle / Checkpoint Control | | | 2 | DNA Damage | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for RECQL5
RECQL5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RECQL5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/43 Interacting proteins for RECQL5 (O947622, 3 ENSP000003176364) via UniProtKB, MINT, STRING, and/or I2D (see all 43)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
RECQL5 for ontologies About GeneDecksing
|
Drugs & Compounds
for RECQL5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RECQL5
Search CenterWatch for drugs/clinical trials and news about RECQL5 / RECQ5
|
Transcripts
for RECQL5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RECQL5 gene (3 alternative transcripts): NM_001003715.3 NM_001003716.3 NM_004259.6 Unigene Cluster for RECQL5: RecQ protein-like 5 Hs.632229 [show with all ESTs]Unigene Representative Sequence: NM_00425918/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000578865(uc002jot.4) ENST00000443199 ENST00000423245(uc010dgk.3)
ENST00000317905(uc010dgl.3) ENST00000581825 ENST00000582548 ENST00000580707
ENST00000579265 ENST00000585205 ENST00000578201 ENST00000583673 ENST00000582464
ENST00000579739 ENST00000581827 ENST00000420326(uc002joz.4 uc002jpa.4 uc002jpb.2)
ENST00000340830 ENST00000584999 ENST00000580078
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 (see all 6)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): RECQL5 (NM_001003716) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RECQL5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RECQL5 |
Additional cDNA sequence: AB006533.1 AB042823.1 AB042824.1 AB042825.1 AF193041.1 AK075084.1 AK304168.1 AL136869.1 BC000570.2 BC005103.1 BC016911.1 BC063440.1 CR533497.1 EF560729.1 15 DOTS entries: DT.75118005 DT.40129987 DT.92428272 DT.120933836 DT.100819207 DT.75197578 DT.92428275 DT.100819212 DT.100819214 DT.100819215 DT.92428270 DT.97810143 DT.120933725 DT.40111528 DT.100028571 1 AceView cDNA sequence: BC042989
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for RECQL5 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | |
| SP2: | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RECQL5
|
Expression
for RECQL5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RECQL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGCGTGCA
About this image
See RECQL5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RECQL5
SOURCE GeneReport for Unigene cluster: Hs.632229
UniProtKB/Swiss-Prot: RECQ5_HUMAN, O94762Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for RECQL5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RECQL5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RECQL5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RECQL5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RECQL5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RECQL5 |
Orthologs
for RECQL5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for RECQL5 gene from 8/28 species (see all 28) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RECQL51 |
RecQ protein-like 5 |
64.61(n)
61.93(a) |
|
373891 XM_001233564.2 XP_001233565.2 |
lizard
(Anolis carolinensis) |
Reptilia |
RECQL56 |
-- |
57(a) |
1 ↔ 1 |
2(113837228-113904142) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.285712 |
Transcribed sequence with weak similarity to protein more |
74.66(n) |
|
57071527 |
fruit fly
(Drosophila melanogaster) |
Insecta |
RecQ51 |
homolog of RecQ |
51.93(n)
44.54(a) |
|
39594 NM_168591.2 NP_729983.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
wrn-13
rcq-51 |
Protein RCQ-51 |
36(a)3
46.81(n)1
40.95(a)1 |
|
II(6554924-6559094)3
1755221 NM_065409.21 NP_497810.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
RecQl31 |
ATP-dependent DNA helicase Q-like 3 |
47.29(n)
38.69(a) |
|
829727 NM_119740.2 NP_195299.2 |
rice
(Oryza sativa) |
Liliopsida |
-- |
DEAD-box ATP-dependent RNA helicase, putative, exp... |
24(a) |
1 ↔ 1 |
2(33078508-33088002) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
recQ6 |
ATP-dependent DNA helicase |
27(a) |
1 → many |
Chromosome(4003887-4005716) |
ENSEMBL Gene Tree for RECQL5 (if available)
TreeFam Gene Tree for RECQL5 (if available) |
Paralogs
for RECQL5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RECQL5 gene
- WRN2 RECQL2 BLM2
2 SIMAP similar genes for RECQL5 using alignment to 11 protein entries: RECQ5_HUMAN (see all proteins):PP1045 RECQL
RECQL5 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RECQL5
PGOHUM00000262967
|
Genomic Variants
for RECQL5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RECQL5 (73622925 - 73663269 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RECQL5
4 CNVs: 5031 49926 30025 30026 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RECQL5 |
|
Disorders
/ Diseases
for RECQL5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RECQL5 for disorders About GeneDecksing
OMIM gene information: 603781
OMIM disorders: --
4  diseases for RECQL5: About MalaCardsrothmund-thomson syndrome baller-gerold syndrome bloom syndrome werner syndrome
5 diseases from the University of Copenhagen DISEASES database for RECQL5:Rothmund-Thomson syndrome Bloom syndrome Werner syndrome Rapadilino syndrome
Baller-Gerold syndrome 5 Novoseek disease relationships for RECQL5 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| rothmund-thomson syndrome |
94.9 |
2 |
12724411 (1), 11738818 (1) |
| bloom syndrome |
90.9 |
2 |
12724411 (1), 20075015 (1) |
| werner syndrome |
86.1 |
1 |
12724411 (1) |
| genetic disorder |
32.4 |
1 |
11032027 (1) |
| cancer |
21.2 |
1 |
18719387 (1) |
Export disorders for RECQL5 gene to outside databases
|
Publications
for RECQL5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RECQL5 gene, integrated from 9 sources (see all 42):
(articles sorted by number of sources associating them with RECQL5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes. (PubMed id 9878247)1, 2, 3, 9 Kitao S.... Shimamoto A. (1998)
- Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing. (PubMed id 10471747)1, 2, 9 Sekelsky J.J.... Hawley R.S. (1999)
- Human RecQ5-beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3-alpha and 3- beta. (PubMed id 10710432)1, 2, 9 Shimamoto A.... Furuichi Y. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Direct inhibition of RNA polymerase II transcription by RECQL5. (PubMed id 19570979)1, 9 AygA1n O....Svejstrup J.Q. (2009)
- RecQL5 promotes genome stabilization through two para llel mechanisms--interacting with RNA polymerase II and acting as a helicase. (PubMed id 20231364)1, 9 Islam M.N....Wang W. (2010)
- A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin. (PubMed id 18562274)1, 9 Aygun O....Liu Y. (2008)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Recruitment and retention dynamics of RECQL5 at DNA do uble strand break sites. (PubMed id 22633600)1 Popuri V....Bohr V.A. (2012)
|
External Searches for RECQL5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RECQL5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RECQL5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RECQL5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RECQL5 gene:
Search GeneIP for patents involving RECQL5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RECQL5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RECQL5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RECQL5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RECQL5 | | | OriGene Protein Over-expression Lysate for RECQL5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RECQL5 | | OriGene 3'-UTR Clone for RECQL5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RECQL5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RECQL5 | | OriGene Custom Protein Services for RECQL5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RECQL5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RECQL5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RECQL5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RECQL5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RECQL5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RECQL5 |
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| | Antibodies & Assays for RECQL5 |
| | | | Search Tocris compounds for RECQL5 |
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 | | | RECQL5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RECQL5 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RECQL5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RECQL5 |
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