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Aliases for REC114 Gene

Aliases for REC114 Gene

  • REC114 Meiotic Recombination Protein 2 3
  • C15orf60 3 4
  • Meiotic Recombination Protein REC114-Like 3
  • Meiotic Recombination Protein REC114 3
  • Chromosome 15 Open Reading Frame 60 2
  • CT147 3

External Ids for REC114 Gene

Previous HGNC Symbols for REC114 Gene

  • C15orf60

Summaries for REC114 Gene

GeneCards Summary for REC114 Gene

REC114 (REC114 Meiotic Recombination Protein) is a Protein Coding gene.

UniProtKB/Swiss-Prot for REC114 Gene

  • May play a role in meiotic DNA double-strand break formation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for REC114 Gene

Genomics for REC114 Gene

Genomic Location for REC114 Gene

73,443,158 bp from pter
73,560,817 bp from pter
117,660 bases
Plus strand

Genomic View for REC114 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for REC114 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for REC114 Gene

No data available for Regulatory Elements for REC114 Gene

Proteins for REC114 Gene

  • Protein details for REC114 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Meiotic recombination protein REC114
    Protein Accession:
    Secondary Accessions:

    Protein attributes for REC114 Gene

    266 amino acids
    Molecular mass:
    29155 Da
    Quaternary structure:
    • Interacts with MEI4.
    • Sequence=AAH55412.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for REC114 Gene

Proteomics data for REC114 Gene at MOPED

Post-translational modifications for REC114 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for REC114 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for REC114 Gene

Domains for REC114 Gene

Protein Domains for REC114 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the REC114 family.
  • Belongs to the REC114 family.
genes like me logo Genes that share domains with REC114: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for REC114 Gene

Function for REC114 Gene

Molecular function for REC114 Gene

UniProtKB/Swiss-Prot Function:
May play a role in meiotic DNA double-strand break formation.

Gene Ontology (GO) - Molecular Function for REC114 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with REC114: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for REC114 Gene

Localization for REC114 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for REC114 Gene

Pathways for REC114 Gene

SuperPathways for REC114 Gene

No Data Available

Interacting Proteins for REC114 Gene

Gene Ontology (GO) - Biological Process for REC114 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006310 DNA recombination IEA --
GO:0051321 meiotic cell cycle IEA --
genes like me logo Genes that share ontologies with REC114: view

No data available for Pathways by source for REC114 Gene

Transcripts for REC114 Gene

mRNA/cDNA for REC114 Gene

(3) REFSEQ mRNAs :
(14) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for REC114 Gene

No ASD Table

Relevant External Links for REC114 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for REC114 Gene

mRNA expression in normal human tissues for REC114 Gene

Protein differential expression in normal tissues for REC114 Gene

This gene is overexpressed in Plasma (67.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for REC114 Gene

genes like me logo Genes that share expressions with REC114: view

Expression partners for REC114 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for REC114 Gene

Orthologs for REC114 Gene

This gene was present in the common ancestor of chordates.

Orthologs for REC114 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C10H15orf60 35
  • 81.12 (n)
  • 76.95 (a)
(Canis familiaris)
Mammalia C30H15orf60 35
  • 79.45 (n)
  • 70.68 (a)
C15orf60 36
  • 73 (a)
(Mus musculus)
Mammalia 2410076I21Rik 35
  • 76.45 (n)
  • 68.73 (a)
2410076I21Rik 16
2410076I21Rik 36
  • 68 (a)
(Pan troglodytes)
Mammalia C15H15orf60 35
  • 99.62 (n)
  • 99.62 (a)
C15orf60 36
  • 97 (a)
(Rattus norvegicus)
Mammalia RGD1311874 35
  • 77.86 (n)
  • 71.43 (a)
(Monodelphis domestica)
Mammalia C15orf60 36
  • 57 (a)
(Ornithorhynchus anatinus)
Mammalia C15orf60 36
  • 55 (a)
(Gallus gallus)
Aves C10H15ORF60 35
  • 65.17 (n)
  • 56.76 (a)
C15orf60 36
  • 45 (a)
(Anolis carolinensis)
Reptilia C15orf60 36
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734605 35
  • 55.09 (n)
  • 43.66 (a)
(Danio rerio)
Actinopterygii C18H15orf60 (1 of 2) 36
  • 38 (a)
C18H15orf60 (2 of 2) 36
  • 41 (a)
Species with no ortholog for REC114:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for REC114 Gene

Gene Tree for REC114 (if available)
Gene Tree for REC114 (if available)

Paralogs for REC114 Gene

No data available for Paralogs for REC114 Gene

Variants for REC114 Gene

Sequence variations from dbSNP and Humsavar for REC114 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs922687 -- 73,556,467(+) GTTCA(A/C)TTCTT intron-variant
rs1280334 -- 73,471,988(-) tttgc(C/T)gtctt intron-variant
rs1481088 -- 73,549,920(+) AAATT(A/G)TGAAC intron-variant
rs1481090 -- 73,527,728(-) GTCTA(G/T)TTTTA intron-variant
rs1481091 -- 73,527,574(-) TAGAC(A/G)GTACA intron-variant

Relevant External Links for REC114 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for REC114 Gene

Disorders for REC114 Gene

No disorders were found for REC114 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for REC114 Gene

Publications for REC114 Gene

  1. Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. (PMID: 20551173) Kumar R. … de Massy B. (Genes Dev. 2010) 2 3
  2. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PMID: 23382691) Lauc G. … Rudan I. (PLoS Genet. 2013) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for REC114 Gene

Sources for REC114 Gene

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