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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RDH13 Gene

protein-coding   GIFtS: 53
GCID: GC19M055556

Retinol Dehydrogenase 13 (All-Trans/9-Cis)

(Previous name: retinol dehydrogenase 13 (all-trans and 9-cis))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Retinol Dehydrogenase 13 (All-Trans/9-Cis)1 2     SDR7C32
Retinol Dehydrogenase 13 (All-Trans And 9-Cis)1 2     Retinol Dehydrogenase 132
Member 31     Short Chain Dehydrogenase/Reductase Family 7C, Member 32
Short Chain Dehydrogenase/Reductase Family 7C1     EC 1.1.1.-3

External Ids:    HGNC: 199781   Entrez Gene: 1127242   Ensembl: ENSG000001604397   UniProtKB: Q8NBN73   

Export aliases for RDH13 gene to outside databases

Previous GC identifers: GC19M055979 GC19M060231 GC19M060247 GC19M051879


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RDH13 Gene:
This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation
of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria
against oxidative stress. Alternatively spliced transcript variants have been described. (provided by RefSeq, Mar
2009)

GeneCards Summary for RDH13 Gene: 
RDH13 (retinol dehydrogenase 13 (all-trans/9-cis)) is a protein-coding gene. Diseases associated with RDH13 include leber congenital amaurosis, and tuberculosis. GO annotations related to this gene include oxidoreductase activity and nucleotide binding. An important paralog of this gene is ENSG00000258466.

UniProtKB/Swiss-Prot: RDH13_HUMAN, Q8NBN7
Function: Does not exhibit retinol dehydrogenase (RDH) activity in vitro




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RDH13 gene promoter:
         NF-1   Zic1   NRSF form 1   Olf-1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RDH13 promoter sequence
   Search SABiosciences Chromatin IP Primers for RDH13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RDH13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

RDH13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RDH13 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M055556:  view genomic region     (about GC identifiers)

Start:
55,550,476 bp from pter      End:
55,582,659 bp from pter
Size:
32,184 bases      Orientation:
minus strand

6/8 alternative locations (see all 8):
Chr19-,NW_003571055 689,525-714,747      Chr19-,NW_003571058 1,026,395-1,051,617      Chr19-,NW_003571059 962,688-987,910     
Chr19-,NW_003571054 947,722-972,944      Chr19-,NW_003571061 756,484-781,706      Chr19-,NW_003571057 1,051,846-1,077,068     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RDH13_HUMAN, Q8NBN7 (See protein sequence)
Recommended Name: Retinol dehydrogenase 13  
Size: 331 amino acids; 35932 Da
Secondary accessions: Q6UX79 Q96G88
Alternative splicing: 2 isoforms:  Q8NBN7-1   Q8NBN7-2   

Explore the universe of human proteins at neXtProt for RDH13: NX_Q8NBN7

Explore proteomics data for RDH13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NBN7

  • RDH13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RDH13 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001139443.1  NP_612421.1  

    ENSEMBL proteins: 
     ENSP00000468422   ENSP00000391121   ENSP00000291892   ENSP00000379547   ENSP00000465538  
     ENSP00000467208   ENSP00000466708   ENSP00000467754  

    Human Recombinant Protein Products for RDH13: 
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    Cloud-Clone Corp. Proteins for RDH13 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    RDH13 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SDRC2: Short chain dehydrogenase/reductase superfamily / Classical SDR fold cluster 2

    4 InterPro protein domains:
     IPR020904 Sc_DH/Rdtase_CS
     IPR002347 Glc/ribitol_DH
     IPR002198 DH_sc/Rdtase_SDR
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q8NBN7

    ProtoNet protein and cluster: Q8NBN7

    2 Blocks protein domains:
    IPB002198 Short-chain dehydrogenase/reductase SDR
    IPB002347 Glucose/ribitol dehydrogenase family signature


    UniProtKB/Swiss-Prot: RDH13_HUMAN, Q8NBN7
    Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family


    RDH13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RDH13_HUMAN, Q8NBN7
    Function: Does not exhibit retinol dehydrogenase (RDH) activity in vitro

         Enzyme Number (IUBMB): EC 1.1.1.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0016491oxidoreductase activity IEA--
    GO:0050662coenzyme binding ----
         
    RDH13 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rdh13):
     homeostasis/metabolism  nervous system  vision/eye 

    RDH13 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Rdh13tm1Xuxn for RDH13

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RDH13 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RDH13 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Visual Cycle in Retinal Rods
    Visual Cycle in Retinal Rods

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for RDH13
        Visual Cycle in Retinal Rods


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RDH13

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for RDH13 (Q8NBN72, 3 ENSP000002918924) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GADD45GO952572, 3, ENSP000002525064MINT-8256261 I2D: score=2 STRING: ENSP00000252506
    MINOS1Q5TGZ03, ENSP000003255624I2D: score=1 STRING: ENSP00000325562
    UBCENSP000003448184STRING: ENSP00000344818
    CYP3A5ENSP000002229824STRING: ENSP00000222982
    PSKH1ENSP000002910414STRING: ENSP00000291041
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----
    GO:0044237cellular metabolic process ----

    RDH13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RDH13

    8 HMDB Compounds for RDH13    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Butanol1-Butanol (see all 10)71-36-3--
    13-OxoODE13-KODE (see all 3)----
    3a,7a,12a,24-Tetrahydroxy-5b-cholestanoyl-CoA3alpha,7alpha,12alpha,24zeta-Tetrahydroxy-5beta-cholestanoyl-CoA (see all 10)----
    3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA (see all 24)----
    3a,7a,12a-Trihydroxy-5b-cholestanoyl-CoA3a,7a,12a-Trihydroxy-5b-cholestan-26-oyl-CoA (see all 28)57458-60-3--
    Butanal1-Butanal (see all 16)123-72-8--
    HydroxyacetoneAcetol (see all 7)116-09-6--
    Pyruvaldehyde1,2-Propanedione (see all 16)78-98-8--

    1 DrugBank Compound for RDH13    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Vitamin A[11,12-3H]-Retinol (see all 18)68-26-8target--17512723

    Search CenterWatch for drugs/clinical trials and news about RDH13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RDH13 gene (2 alternative transcripts): 
    NM_001145971.1  NM_138412.3  

    Unigene Clusters for RDH13:

    Retinol dehydrogenase 13 (all-trans/9-cis)
    Hs.327631  [show with all ESTs], Hs.731615  [show with all ESTs]
    Unigene Representative Sequences: AK122764, AK096798
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000592423 ENST00000586331 ENST00000591960 ENST00000415061(uc010esr.1 uc002qio.3 uc010yfq.1)
    ENST00000291892 ENST00000396247(uc002qip.2) ENST00000592573 ENST00000587721
    ENST00000589605 ENST00000589305 ENST00000586945 ENST00000587026 ENST00000591603
    ENST00000588306 ENST00000591023 ENST00000589197 ENST00000590349 ENST00000587373

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate RDH13:
    hsa-miR-376a*
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK096798.1 AL833150.1 

    22 DOTS entries:

    DT.100027715  DT.85105454  DT.97837853  DT.95157350  DT.95374245  DT.99999377  DT.121640885  DT.91987183 
    DT.121505693  DT.40129461  DT.92417262  DT.92423309  DT.95374248  DT.95374250  DT.121505637  DT.121505649 
    DT.121505653  DT.208984  DT.40122533  DT.40125561  DT.91970276  DT.95313681 

    24/228 AceView cDNA sequences (see all 228):

    AI744631 AI188687 BX099264 AW137350 BU848946 AI300806 AI928256 BE676766 
    AW469077 BF939371 BQ682333 AI990886 BM829123 AA134945 AA565318 AI800708 
    BF590610 AI361494 CB243256 CK824969 BE675517 AI924506 AI189961 BF195666 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RDH13 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b
    SP1:        -     -     -                 -     -     -                       -                 -               
    SP2:                                      -     -     -                       -                 -               
    SP3:                                      -     -     -                                                         
    SP4:                                            -     -                       -                                 
    SP5:                          -           -     -     -                                                         


    ECgene alternative splicing isoforms for RDH13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RDH13 expression in normal human tissues (normalized intensities)      RDH13 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAGTCCAAA
    RDH13 Expression
    About this image


    RDH13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Midbrain tegmentum
             ganglion/cranial   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             limb/hindlimb   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See RDH13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RDH13

    SOURCE GeneReport for Unigene clusters: Hs.327631 Hs.731615

    UniProtKB/Swiss-Prot: RDH13_HUMAN, Q8NBN7
    Tissue specificity: Expressed mostly in eye, pancreas, placenta and lung. In the retina, detected in the inner
    segment of the photoreceptor cells. Weak signals were observed in a small population of inner nuclear neurons and
    the inner plexiform layer

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RDH13 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rdh131 , 5 retinol dehydrogenase 13 (all-trans and 9-cis)1, 5 84.01(n)1
    86.52(a)1
      7 (2.56 cM)5
    1088411  NM_175372.41  NP_780581.11 
     44247705 
    African clawed frog
    (Xenopus laevis)
    Amphibia 480126802   -- 74.37(n)    48012680 
    zebrafish
    (Danio rerio)
    Actinopterygii sbcb4642 sbcb464 73.53(n)   368337  CB923501.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG304911 CG30491 55.8(n)
    52.4(a)
      35704  NM_136462.1  NP_610306.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G025401 Rossmann-fold NAD(P)-binding domain-containing protein 50.12(n)
    43.01(a)
      831913  NM_120332.3  NP_568102.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g01517001 hypothetical protein 52.07(n)
    46.35(a)
      4324493  NM_001048577.1  NP_001042042.1 


    ENSEMBL Gene Tree for RDH13 (if available)
    TreeFam Gene Tree for RDH13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RDH13 gene
    ENSG000002584662  DHRS122  WWOX2  DHRSX2  RDH122  DHRS132  RDH142  RDH112  
    9 SIMAP similar genes for RDH13 using alignment to 5 protein entries:     RDH13_HUMAN (see all proteins):
    RDH12    RDH11    RDH14    DHRS13    DHRSX    BDH2
    WWOX    DHRS12    HSD17B7

    RDH13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/997 SNPs in RDH13 are shown (see all 997)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1449422841,2
    Cuntested155568047(+) ACTCTC/G/TGGATA 6 Q R mis11EU 1323
    rs1816097321,2
    --55555234(+) TTAAAC/TGGTTA 4 -- ds50010--------
    rs796343291,2
    C--55555295(+) TTTTT-/CT/TC 
            
    TTTTT
    4 -- ds50010--------
    rs603480011,2
    C--55555296(+) TTTTT-/CT/TC 
            
    TTTTT
    4 -- ds50010--------
    rs16544421,2
    C,F--55555366(+) TGCAAG/TCTCCG 4 -- ds50015Minor allele frequency- T:0.22NA CSA 9
    rs16712191,2
    C,F,A--55555378(+) CTCCCG/AGCTTC 4 -- ds50011Minor allele frequency- A:0.00NA 2
    rs16712201,2
    C,F,A--55555380(+) CCCAGG/CTTCAC 4 -- ds50011Minor allele frequency- C:0.00NA 2
    rs602581471,2
    C,F--55555409(+) CCTCCC/TGAGTA 4 -- ds50012Minor allele frequency- T:0.50NA 4
    rs1853531391,2
    C--55555437(+) CCACCA/CCCATG 4 -- ds50010--------
    rs1496525881,2
    --55555522(+) ACCTCA/GTGATC 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for RDH13 (55550476 - 55582659 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/14 variations for RDH13 (see all 14):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2718944CNV Deletion23290073
    esv2667609CNV Deletion23128226
    esv2672890CNV Deletion23128226
    esv2671441CNV Deletion23128226
    esv2718872CNV Deletion23290073
    nsv912448CNV Loss21882294
    nsv833880CNV Loss17160897
    nsv817874CNV Loss17921354
    esv9070CNV Loss19470904
    nsv912446CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for RDH13:    About MalaCards
    leber congenital amaurosis    tuberculosis    retinitis    neuronitis


    RDH13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RDH13
    Human Genome Epidemiology (HuGE) Navigator: RDH13 (1 document)

    Export disorders for RDH13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RDH13 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with RDH13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina. (PubMed id 12226107)1, 2, 3 Haeseleer F.... Palczewski K. (2002)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    7. Human retinol dehydrogenase 13 (RDH13) is a mitochond rial short-chain dehydrogenase/reductase with a retinaldehyde reductase activit y. (PubMed id 18039331)1, 9 Belyaeva O.V....Kedishvili N.Y. (2008)
    8. MINOS1 is a conserved component of mitofilin complexe s and required for mitochondrial function and cristae organization. (PubMed id 22114354)1 Alkhaja A.K....Deckers M. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 112724 HGNC: 19978 AceView: RDH13 Ensembl:ENSG00000160439 euGenes: HUgn112724
    ECgene: RDH13 H-InvDB: RDH13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RDH13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RDH13 gene:
    Search GeneIP for patents involving RDH13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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