Aliases for RDH13 Gene
External Ids for RDH13 Gene
Previous GeneCards Identifiers for RDH13 Gene
This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
GeneCards Summary for RDH13 Gene
RDH13 (Retinol Dehydrogenase 13 (All-Trans/9-Cis)) is a Protein Coding gene. Diseases associated with RDH13 include leber congenital amaurosis. Among its related pathways are Signaling by GPCR and Visual Cycle in Retinal Rods. GO annotations related to this gene include oxidoreductase activity and coenzyme binding. An important paralog of this gene is DHRS12.
UniProtKB/Swiss-Prot for RDH13 Gene
Does not exhibit retinol dehydrogenase (RDH) activity in vitro