Aliases for RDH10 Gene
External Ids for RDH10 Gene
Previous GeneCards Identifiers for RDH10 Gene
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
GeneCards Summary for RDH10 Gene
RDH10 (Retinol Dehydrogenase 10 (All-Trans)) is a Protein Coding gene. Diseases associated with RDH10 include fundus albipunctatus. Among its related pathways are Signaling by GPCR and Disease. GO annotations related to this gene include retinol dehydrogenase activity and NADP-retinol dehydrogenase activity. An important paralog of this gene is HSD17B11.
UniProtKB/Swiss-Prot for RDH10 Gene
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.