Aliases for RDH10 Gene
External Ids for RDH10 Gene
Previous GeneCards Identifiers for RDH10 Gene
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
GeneCards Summary for RDH10 Gene
RDH10 (Retinol Dehydrogenase 10 (All-Trans)) is a Protein Coding gene. Diseases associated with RDH10 include cone-rod dystrophy 17 and total anomalous pulmonary venous return. Among its related pathways are Signaling by GPCR and Metabolism. GO annotations related to this gene include oxidoreductase activity and NADP-retinol dehydrogenase activity. An important paralog of this gene is HSD17B11.
UniProtKB/Swiss-Prot for RDH10 Gene
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.