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Aliases for RD3L Gene

Aliases for RD3L Gene

  • Retinal Degeneration 3-Like 2 3 5
  • Retinal Degeneration Protein 3-Like 3 4
  • TDRD9 Antisense 1 2 3
  • TDRD9 Antisense RNA 1 (Non-Protein Coding) 3
  • Protein RD3-Like 3
  • TDRD9-AS1 3
  • TDRD9AS1 3

External Ids for RD3L Gene

Previous HGNC Symbols for RD3L Gene

  • TDRD9-AS1

Previous GeneCards Identifiers for RD3L Gene

  • GC14M104410

Summaries for RD3L Gene

GeneCards Summary for RD3L Gene

RD3L (Retinal Degeneration 3-Like) is a Protein Coding gene. An important paralog of this gene is RD3.

Additional gene information for RD3L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RD3L Gene

Genomics for RD3L Gene

Regulatory Elements for RD3L Gene

Enhancers for RD3L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H103107 1.9 FANTOM5 Ensembl ENCODE dbSUPER 5.2 +831.8 831835 6.7 HDGF PKNOX1 ATF1 SIN3A GLIS2 ZNF143 FOS ATF7 RUNX3 PAF1 XRCC3 TNFAIP2 ENSG00000259444 RCOR1 TRAF3 RD3L EIF5 MARK3 BAG5 APOPT1
GH14H103943 0.8 ENCODE 0.7 -1.6 -1621 0.8 HDAC1 PKNOX1 ATF1 TBL1XR1 NFRKB TCF12 GATA2 ATF7 CREM NCOA1 TDRD9 C14orf2 ASPG RD3L GC14P103968
GH14H103931 1.3 FANTOM5 Ensembl ENCODE 0.4 +9.5 9508 3.2 ELF3 SOX13 FOXA2 SAP130 CEBPG RARA ZNF7 TEAD3 POLR2A SOX5 TDRD9 C14orf2 ENSG00000202275 RD3L
GH14H103930 0.7 Ensembl 0.4 +12.1 12108 0.4 SMARCE1 PKNOX1 ESRRA ZNF687 DPF2 RARA ZKSCAN1 FOXA1 ZNF217 CTBP1 TDRD9 RD3L
GH14H103932 0.7 ENCODE 0.4 +11.8 11830 0.2 SMARCE1 PKNOX1 ESRRA ZNF687 DPF2 RARA ZKSCAN1 FOXA1 ZNF217 CTBP1 ENSG00000202275 TDRD9 RD3L
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RD3L on UCSC Golden Path with GeneCards custom track

Genomic Locations for RD3L Gene

Genomic Locations for RD3L Gene
1,883 bases
Minus strand

Genomic View for RD3L Gene

Genes around RD3L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RD3L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RD3L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RD3L Gene

Proteins for RD3L Gene

  • Protein details for RD3L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein RD3-like
    Protein Accession:

    Protein attributes for RD3L Gene

    198 amino acids
    Molecular mass:
    23209 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RD3L Gene

Post-translational modifications for RD3L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RD3L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RD3L Gene

Domains & Families for RD3L Gene

Gene Families for RD3L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RD3L Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RD3L: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RD3L Gene

Function for RD3L Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RD3L Gene

Localization for RD3L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RD3L Gene

Pathways & Interactions for RD3L Gene

No Data Available

Interacting Proteins for RD3L Gene

Selected Interacting proteins: P0DJH9-RD3L_HUMAN for RD3L Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for RD3L Gene


No data available for Pathways by source and SIGNOR curated interactions for RD3L Gene

Drugs & Compounds for RD3L Gene

No Compound Related Data Available

Transcripts for RD3L Gene

mRNA/cDNA for RD3L Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RD3L Gene

Retinal degeneration 3-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for RD3L Gene

No ASD Table

Relevant External Links for RD3L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RD3L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RD3L Gene

mRNA differential expression in normal tissues according to GTEx for RD3L Gene

This gene is overexpressed in Heart - Left Ventricle (x31.9) and Heart - Atrial Appendage (x17.5).

Protein differential expression in normal tissues from HIPED for RD3L Gene

This gene is overexpressed in Bone (47.5) and Testis (18.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RD3L Gene

Protein tissue co-expression partners for RD3L Gene

NURSA nuclear receptor signaling pathways regulating expression of RD3L Gene:


SOURCE GeneReport for Unigene cluster for RD3L Gene:

genes like me logo Genes that share expression patterns with RD3L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RD3L Gene

Orthologs for RD3L Gene

This gene was present in the common ancestor of chordates.

Orthologs for RD3L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RD3L 33
  • 99.66 (n)
(Canis familiaris)
Mammalia RD3L 33 34
  • 89.06 (n)
(Bos Taurus)
Mammalia RD3L 33 34
  • 84.85 (n)
(Mus musculus)
Mammalia BC048943 33 34
  • 81.39 (n)
Rd3l 16
(Rattus norvegicus)
Mammalia RGD1305627 33
  • 81.27 (n)
(Ornithorhynchus anatinus)
Mammalia RD3L 34
  • 79 (a)
(Monodelphis domestica)
Mammalia RD3L 34
  • 75 (a)
(Gallus gallus)
Aves RD3L 34
  • 75 (a)
LOC772190 33
  • 74.92 (n)
(Anolis carolinensis)
Reptilia RD3L 34
  • 75 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rd3l 33
  • 69.08 (n)
(Danio rerio)
Actinopterygii si:ch211-253p18.5 33
  • 49.47 (n)
RD3L 34
  • 30 (a)
Species where no ortholog for RD3L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RD3L Gene

Gene Tree for RD3L (if available)
Gene Tree for RD3L (if available)

Paralogs for RD3L Gene

Paralogs for RD3L Gene

genes like me logo Genes that share paralogs with RD3L: view

Variants for RD3L Gene

Sequence variations from dbSNP and Humsavar for RD3L Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1001085720 -- 103,941,430(+) GTTGA(A/G)CTTGT intron-variant, reference, missense
rs1001416370 -- 103,939,964(+) ACCAG(C/T)AAATC intron-variant
rs1001451802 -- 103,943,006(+) ACAAA(A/G)TCTTA intron-variant, upstream-variant-2KB
rs1001558113 -- 103,941,053(+) AGATG(C/T)AGACT intron-variant, reference, missense
rs1002172105 -- 103,942,974(+) AAATA(A/G)AGGCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RD3L Gene

Variant ID Type Subtype PubMed ID
esv2760013 CNV loss 17122850
nsv1054574 CNV loss 25217958

Variation tolerance for RD3L Gene

Gene Damage Index Score: 5.17; 69.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RD3L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RD3L Gene

Disorders for RD3L Gene

Relevant External Links for RD3L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RD3L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RD3L Gene

Publications for RD3L Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 4 60
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 60

Products for RD3L Gene

Sources for RD3L Gene

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