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RD3 Gene

protein-coding   GIFtS: 48
GCID: GC01M211649

Retinal Degeneration 3

(Previous name: chromosome 1 open reading frame 36)
(Previous symbol: C1orf36)
  See RD3-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Retinal Degeneration 31 2
C1orf361 2 3 5
Retinal Degeneration Protein 32 3
LCA122 5
Chromosome 1 Open Reading Frame 361
Protein RD32

External Ids:    HGNC: 196891   Entrez Gene: 3430352   Ensembl: ENSG000001985707   OMIM: 1800405   UniProtKB: Q7Z3Z23   
ORGUL members:         

Export aliases for RD3 gene to outside databases

Previous GC identifers: GC01M209717 GC01M182327


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RD3 Gene:
This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in
the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal
degeneration. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Sep 2009)

GeneCards Summary for RD3 Gene:
RD3 (retinal degeneration 3) is a protein-coding gene. Diseases associated with RD3 include rd3-related leber congenital amaurosis, and retinal degeneration. An important paralog of this gene is RD3L.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the RD3 gene promoter:
         MEF-2A   RFX1   AP-4   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRD3 promoter sequence
   Search Chromatin IP Primers for RD3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q32.3

RD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RD3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M211649:  view genomic region     (about GC identifiers)

Start:
211,649,864 bp from pter      End:
211,666,259 bp from pter
Size:
16,396 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RD3_HUMAN, Q7Z3Z2 (See protein sequence)
Recommended Name: Protein RD3  
Size: 195 amino acids; 22704 Da
Secondary accessions: A8K595

Explore the universe of human proteins at neXtProt for RD3: NX_Q7Z3Z2

Explore proteomics data for RD3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001158160.1  NP_898882.1  

    ENSEMBL proteins: 
     ENSP00000355969  

    RD3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RD3

     
    Search eBioscience for Proteins for RD3 

    RD3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals RD3 Antibody
    Abcam antibodies for RD3
    Cloud-Clone Corp. Antibodies for RD3
    Search ThermoFisher Antibodies for RD3
    LSBio Antibodies in human, mouse, rat for RD3

    RD3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RD3
    Cloud-Clone Corp. CLIAs for RD3
    Search eBioscience for ELISAs for RD3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR028092 RD3

    Graphical View of Domain Structure for InterPro Entry Q7Z3Z2

    ProtoNet protein and cluster: Q7Z3Z2


    Find genes that share domains with RD3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rd3):
     nervous system  vision/eye 

    Find genes that share phenotypes with RD3           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RD3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RD3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RD3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RD3

    miRNA
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    Block miRNA regulation of human, mouse, rat RD3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RD3 (see all 11):
    hsa-miR-492 hsa-miR-103b hsa-miR-3651 hsa-miR-2278 hsa-miR-3647-3p hsa-miR-3150a-3p hsa-miR-182 hsa-miR-491-5p
    SwitchGear 3'UTR luciferase reporter plasmidRD3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RD3

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for RD3

    Clone
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    OriGene clones in human, mouse for RD3 (see all 12)
    OriGene ORF clones in mouse, rat for RD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RD3 (NM_000796)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RD3

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RD3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    nucleus2
    cytosol1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RD3
    Interactions:

        Search GeneGlobe Interaction Network for RD3

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007601visual perception IEA--
    GO:0050896response to stimulus IEA--
    GO:0060041retina development in camera-type eye IEA--

    Find genes that share ontologies with RD3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RD3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RD3 gene (2 alternative transcripts): 
    NM_001164688.1  NM_183059.2  

    Unigene Cluster for RD3:

    Retinal degeneration 3
    Hs.632495  [show with all ESTs]
    Unigene Representative Sequence: NM_183059
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000484910 ENST00000367002(uc001him.2 uc001hin.2 uc009xda.2)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RD3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RD3 (see all 11):
    hsa-miR-492 hsa-miR-103b hsa-miR-3651 hsa-miR-2278 hsa-miR-3647-3p hsa-miR-3150a-3p hsa-miR-182 hsa-miR-491-5p
    SwitchGear 3'UTR luciferase reporter plasmidRD3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RD3
    Predesigned siRNA for gene silencing in human, mouse, rat RD3
    Clone
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    OriGene clones in human, mouse for RD3 (see all 12)
    OriGene ORF clones in mouse, rat for RD3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RD3 (NM_000796)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RD3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RD3
    OriGene qSTAR qPCR primer pairs in human, mouse for RD3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RD3
      QuantiTect SYBR Green Assays in human, mouse, rat RD3
      QuantiFast Probe-based Assays in human, mouse, rat RD3

    Additional mRNA sequence: 

    AK291210.1 AY191519.1 BC035651.1 BC065541.1 BX647803.1 

    3 DOTS entries:

    DT.99941796  DT.102822814  DT.91668805 

    Selected AceView cDNA sequences (see all 33):

    BU734167 AA364772 BC035651 BM451791 BM451541 BC065541 BQ637404 NM_183059 
    BM709674 AY191519 AW963480 BU193531 BM450722 AA708109 BQ423977 BU176577 
    H56707 BU153642 AA719822 BX647803 AV722566 BM478345 BE618160 BU734084 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RD3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4
    SP1:              -                     
    SP2:              -                     
    SP3:                                    


    ECgene alternative splicing isoforms for RD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGGTCCAGA
    RD3 Expression
    About this image


    RD3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Epithelial Cells
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
    RD3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RD3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632495

    UniProtKB/Swiss-Prot: RD3_HUMAN, Q7Z3Z2
    Tissue specificity: Preferentially expressed in retina

        Custom PCR Arrays for RD3
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    QuantiFast Probe-based Assays in human, mouse, rat RD3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RD3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rd31 , 5 retinal degeneration 31, 5 83.25(n)1
    85.64(a)1
      1 (97.09 cM)5
    740231  NM_023727.31  NP_076216.21 
     1919773735 
    chicken
    (Gallus gallus)
    Aves RD31 retinal degeneration 3 69.26(n)
    67.88(a)
      421378  XM_419438.4  XP_419438.1 
    lizard
    (Anolis carolinensis)
    Reptilia RD36
    retinal degeneration 3
    66(a)
    1 ↔ 1
    1(237921217-237949248)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rd31 retinal degeneration 3 64.96(n)
    60.51(a)
      100493931  XM_004914081.1  XP_004914138.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rd31 retinal degeneration 3 62.39(n)
    58.29(a)
      791149  NM_001080631.1  NP_001074100.1 


    ENSEMBL Gene Tree for RD3 (if available)
    TreeFam Gene Tree for RD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RD3 gene
    RD3L2  

    Find genes that share paralogs with RD3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RD3 (see all 478)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs722471771,2
    C--182339651(+) GGTAT-/TTCTTTAG 4 -- int1 cds10--------
    rs1507917341,2
    C--182339651(+) GGTAT-/TTCTTTAG 2 -- int10--------
    rs2015216281,2
    C--182339653(-) CTAAAA/GANNNN 2 -- int10--------
    rs114636561,2
    C--182342273(+) CTCAAG/-ATTTT 2 -- ut511Minor allele frequency- -:0.00CSA 2
    rs75194961,2
    C,F,A--182344788(+) GCGTGC/TGTGTG 2 -- us2k15Minor allele frequency- T:0.22WA NA CSA 9
    rs586204641,2
    C--211650796(+) GTCTC-/AAAAAA 2 -- ut310--------
    rs105807871,2
    C--211653994(+) TTCCT-/ACAC  
            
    ACACA
    2 -- int10--------
    rs343848691,2
    C--211655564(+) CGTTT-/AAAAAA 2 -- int11Minor allele frequency- A:0.50NA 2
    rs1125801601,2
    C,F--211659935(+) TCTGTC/TATCTC 2 -- int11Minor allele frequency- T:0.50CSA 2
    rs601608021,2
    C--211661875(+) AAAAA-/ACCCAC 2 -- int11Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for RD3 (211649864 - 211666259 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RD3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675306CNV Deletion23128226
    nsv832514CNV Loss17160897
    esv29853CNV Loss19812545

    Human Gene Mutation Database (HGMD): RD3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RD3
    DNA2.0 Custom Variant and Variant Library Synthesis for RD3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 180040   
    OMIM disorders: 610612  
    UniProtKB/Swiss-Prot: RD3_HUMAN, Q7Z3Z2
  • Leber congenital amaurosis 12 (LCA12) [MIM:610612]: A severe dystrophy of the retina, typically becoming
    evident in the first years of life. Visual function is usually poor and often accompanied by nystagmus, sluggish
    or near-absent pupillary responses, photophobia, high hyperopia and keratoconus. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 6 diseases for RD3:    
    About MalaCards
    rd3-related leber congenital amaurosis    retinal degeneration    leber congenital amaurosis 12    leber congenital amaurosis 17
    progressive supranuclear palsy    leber congenital amaurosis

    3 diseases from the University of Copenhagen DISEASES database for RD3:
    Progressive supranuclear palsy     Leber congenital amaurosis     Pick's disease

    Find genes that share disorders with RD3           About GenesLikeMe

    GeneTests: RD3
    GeneReviews: RD3
    Genetic Association Database (GAD): RD3

    Export disorders for RD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RD3 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with RD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of C1orf36, a transcript highly expressed in photoreceptor cells, and mutation analysis in retinitis pigmentosa. (PubMed id 12914764)1, 2, 3 Lavorgna G....Banfi S. (Biochem. Biophys. Res. Commun. 2003)
    2. Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. (PubMed id 17186464)1, 2 Friedman J.S.... Swaroop A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Union makes strength: a worldwide collaborative genetic and clinical study to provide a comprehensive survey of RD3 mutations and delineate the associated phenotype. (PubMed id 23308101)1 Perrault I....Rozet J.M. (PLoS ONE 2013)
    5. Genome-wide association study of retinopathy in individuals without diabetes. (PubMed id 23393555)1 Jensen R.A....Wong T.Y. (PLoS ONE 2013)
    6. Mutations in RD3 are associated with an extremely rare and severe form of early onset retinal dystrophy. (PubMed id 22531706)1 Preising M.N....Lorenz B. (amp 2012)
    7. Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins. (PubMed id 21928830)1 Peshenko I.V....Dizhoor A.M. (Biochemistry 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Mutation survey of known LCA genes and loci in the Saudi Arabian population. (PubMed id 18936139)1 Li Y....Chen R. (amp 2009)
    10. A genome-wide association study of sporadic ALS in a homogenous Irish population. (PubMed id 18057069)4 Cronin S....Hardiman O. (Hum. Mol. Genet. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 343035 HGNC: 19689 AceView: C1orf36 Ensembl:ENSG00000198570 euGenes: HUgn343035
    ECgene: RD3 H-InvDB: RD3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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