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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RCSD1 Gene

protein-coding   GIFtS: 45
GCID: GC01P167599

RCSD domain containing 1

 Explore 6 diseases affiliated with
RCSD1 via our new
 Human Malady Compendium 
Biological research products
for RCSD1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RCSD Domain Containing 11 2     RCSD Domain-Containing Protein 12 3
MK2S41 2     MGC218541
Protein Kinase Substrate CapZIP2 3     CapZ-Interacting Protein2
CAPZIP2 3     Protein Kinase Substrate MK2S42

External Ids:    HGNC: 283101   Entrez Gene: 922412   Ensembl: ENSG000001987717   OMIM: 6105795   UniProtKB: Q6JBY93   

Export aliases for RCSD1 gene to outside databases

Previous GC identifers: GC01P164331 GC01P165865 GC01P138845


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CPZIP_HUMAN, Q6JBY9
Function: Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin
filament assembly




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RCSD1 gene promoter:
         GR   AP-1   ATF-2   HSF1 (long)   CREB   deltaCREB   HSF1short   c-Jun   GR-alpha   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRCSD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RCSD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RCSD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.2   Ensembl cytogenetic band:  1q24.2   HGNC cytogenetic band: 1q24.2

RCSD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RCSD1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P167599:  view genomic region     (about GC identifiers)

Start:
167,599,330 bp from pter      End:
167,675,486 bp from pter
Size:
76,157 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CPZIP_HUMAN, Q6JBY9 (See protein sequence)
Recommended Name: CapZ-interacting protein  
Size: 416 amino acids; 44504 Da
Subunit: Interacts with CAPZA2 and CAPZB
Sequence caution: Sequence=CAB70910.1; Type=Erroneous initiation;
Secondary accessions: B1AK48 Q4G0E7 Q6IN93 Q8IZM2 Q96DX0 Q9NST4
Alternative splicing: 2 isoforms:  Q6JBY9-1   Q6JBY9-2   

Explore the universe of human proteins at neXtProt for RCSD1: NX_Q6JBY9

Post-translational modifications:

  • Dephosphorylation results in its dissociation from CAPZA21
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6JBY9

  • RCSD1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_443094.3  
    ENSEMBL proteins: 
     ENSP00000356828   ENSP00000355291   ENSP00000439409  

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    Novus Biologicals RCSD1 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RCSD1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005884actin filament IC15850461


    RCSD1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RCSD1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RCSD1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007850 RCSD

    Graphical View of Domain Structure for InterPro Entry Q6JBY9

    ProtoNet protein and cluster: Q6JBY9

    UniProtKB/Swiss-Prot: CPZIP_HUMAN, Q6JBY9
    Similarity: Contains 1 RCSD domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CPZIP_HUMAN, Q6JBY9
    Function: Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin
    filament assembly

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    hsa-miR-4291 hsa-miR-146a hsa-miR-554 hsa-miR-3155 hsa-miR-484 hsa-miR-33a* hsa-miR-3142 hsa-miR-214
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    Inhib. RNA
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCSD1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051015actin filament binding IPI15850461


    RCSD1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RCSD1:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RCSD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/44 Interacting proteins for RCSD1 (ENSP000003568284) via UniProtKB, MINT, STRING, and/or I2D (see all 44)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTA1ENSP000003556454STRING: ENSP00000355645
    ACTC1ENSP000002903784STRING: ENSP00000290378
    ACTN2ENSP000003555374STRING: ENSP00000355537
    AMOTENSP000003610274STRING: ENSP00000361027
    APC2ENSP000002336074STRING: ENSP00000233607
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003009skeletal muscle contraction ISS--
    GO:0071474cellular hyperosmotic response IDA15850461


    RCSD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RCSD1
    Search CenterWatch for drugs/clinical trials and news about RCSD1 / CPZIP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RCSD1 gene: 
    NM_052862.3  

    Unigene Cluster for RCSD1:

    RCSD domain containing 1
    Hs.493867  [show with all ESTs]
    Unigene Representative Sequence: AF545852
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367854(uc001gem.3 uc010pli.2) ENST00000361496 ENST00000475127
    ENST00000472038 ENST00000461790 ENST00000537350

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate RCSD1 (see all 13):
    hsa-miR-4291 hsa-miR-146a hsa-miR-554 hsa-miR-3155 hsa-miR-484 hsa-miR-33a* hsa-miR-3142 hsa-miR-214
    SwitchGear 3'UTR luciferase reporter plasmidRCSD1 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RCSD1 (see all 7)
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RCSD1
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    Additional cDNA sequence: 

    AF545852.1 AK025425.1 AK124221.1 AK130798.1 AL137762.1 AL833211.1 AY530954.1 BC013186.1 
    BC072399.1 BC098426.1 BC101536.1 BC101562.1 BC143428.1 

    7 DOTS entries:

    DT.109341  DT.101968387  DT.40243476  DT.92425297  DT.92425298  DT.92425299  DT.95280941 

    24/183 AceView cDNA sequences (see all 183):

    AK124221 BC072399 AI660357 BI491018 BC013186 H22137 CF138903 BQ051659 
    CR618927 AW408550 BM684348 BM479517 BF507709 CR618640 BX281922 AA490598 
    AA490793 BQ431021 AA651889 AI573014 T77359 AA425076 AI696275 CA748758 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RCSD1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
    SP1:              -                                       
    SP2:              -           -                           
    SP3:                                                      


    ECgene alternative splicing isoforms for RCSD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RCSD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    RCSD1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeHindgutHindgut Endoderm CellsEndoderm
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    LungTracheaBasal CellsLung
    BrainMeningesBrain
    Gut TubeHindgutGut Tube
    Gut TubeMidgutGut Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RCSD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RCSD1

    SOURCE GeneReport for Unigene cluster: Hs.493867

    UniProtKB/Swiss-Prot: CPZIP_HUMAN, Q6JBY9
    Tissue specificity: Highly expressed in skeletal muscle and more weakly in cardiac muscle. Also expressed in several
    lymphoid organs, including spleen, thymus, peripheral blood leukocytes, lymph node and bone marrow

        SABiosciences Custom PCR Arrays for RCSD1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCSD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for RCSD1 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rcsd11 , 5 RCSD domain containing 11, 5 72.47(n)1
    65.44(a)1
      1 (72.99 cM)5
    2265941  NM_178593.31  NP_848708.21 
     1656489455 
    chicken
    (Gallus gallus)
    Aves RCSD11 RCSD domain containing 1 59.66(n)
    54.44(a)
      418443  NM_001030789.1  NP_001025960.1 
    lizard
    (Anolis carolinensis)
    Reptilia RCSD16
    --
    63(a)
    1 ↔ 1
    3(163825318-163831683)
    zebrafish
    (Danio rerio)
    Actinopterygii dub1 duboraya 47.1(n)
    42.39(a)
      566846  NM_001045422.1  NP_001038887.1 


    ENSEMBL Gene Tree for RCSD1 (if available)
    TreeFam Gene Tree for RCSD1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1710 NCBI SNPs in RCSD1 are shown (see all 1710    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75422071,2
    C,F,A,H,--138882636(+) GAGACC/TGGACC 1 -- us2k117Minor allele frequency- T:0.06NS EA NA WA 1870
    rs559807091,2
    C--138882907(+) ATTATG/AATAGA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs594929331,2
    C,--138883126(+) TATCAA/GTCCCT 1 -- us2k12Minor allele frequency- G:0.04WA 120
    rs778497511,2
    C,--138883800(+) ATGTCA/TCATCT 1 -- us2k12Minor allele frequency- T:0.15CSA WA 120
    rs781219121,2
    F,--138884044(+) CAAGAT/CGTACT 1 -- nc-transcript-variant1Minor allele frequency- C:0.06WA 118
    rs37539271,2
    C,F,H,--138884364(+) TCCCCT/CATGCA 1 -- nc-transcript-variant3Minor allele frequency- C:0.10NA WA 244
    rs741206191,2
    C,--138884386(+) TACAGG/TCAAAG 1 -- nc-transcript-variant1Minor allele frequency- T:0.50WA 2
    rs753776931,2
    C,F,--138884499(+) TAGGGC/TTATCT 1 -- nc-transcript-variant1Minor allele frequency- T:0.12WA 118
    rs121332431,2
    --138884693(+) AGGCTC/GTAGTC 1 -- nc-transcript-variant0--------
    rs1996828781,2
    C--138885306(+) CACACA/GCNNNN 1 -- nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for RCSD1 (167599330 - 167675486 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RCSD1: --

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for RCSD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RCSD1 for disorders           About GeneDecksing

    OMIM gene information: 610579    OMIM disorders: --

    6 diseases for RCSD1:    About MalaCards
    acute lymphoblastic leukemia    lymphoblastic leukemia    essential hypertension    hypertension
    t-cell leukemia    leukemia

    Human Genome Epidemiology (HuGE) Navigator: RCSD1 (2 documents)

    Export disorders for RCSD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RCSD1 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with RCSD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The phosphorylation of CapZ-interacting protein (CapZIP) by stress- activated protein kinases triggers its dissociation from CapZ. (PubMed id 15850461)1, 2 Eyers C.E.... Cohen P. (2005)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    4. Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (2009)
    5. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    6. Follow-up of a major linkage peak on chromosome 1 rev eals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1 Ehret G.B....Chakravarti A. (2009)
    7. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PubMed id 19064610)1 Cheung C.L....Kung A.W. (2009)
    8. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)2 Carrascal M.... Abian J. (2008)
    9. A new partner gene fused to ABL1 in a t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia. (PubMed id 17541395)1 De Braekeleer E....De Braekeleer M. (2007)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 92241 HGNC: 28310 AceView: MK2S4 Ensembl:ENSG00000198771 euGenes: HUgn92241
    ECgene: RCSD1 H-InvDB: RCSD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RCSD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RCSD1 gene:
    Search GeneIP for patents involving RCSD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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