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RCOR3 Gene

protein-coding   GIFtS: 52
GCID: GC01P211433

REST Corepressor 3

  Search for RCOR3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
REST Corepressor 31 2
KIAA13433

External Ids:    HGNC: 255941   Entrez Gene: 557582   Ensembl: ENSG000001176257   UniProtKB: Q9P2K33   

Export aliases for RCOR3 gene to outside databases

Previous GC identifers: GC01P208513 GC01P207821 GC01P209499 GC01P182109


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RCOR3 Gene:
RCOR3 (REST corepressor 3) is a protein-coding gene. GO annotations related to this gene include chromatin binding. An important paralog of this gene is RCOR2.

UniProtKB/Swiss-Prot: RCOR3_HUMAN, Q9P2K3
Function: May act as a component of a corepressor complex that represses transcription (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for RCOR3
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRCOR3 promoter sequence
   Search Chromatin IP Primers for RCOR3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RCOR3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.2   Ensembl cytogenetic band:  1q32.2   HGNC cytogenetic band: 1q32.3

RCOR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RCOR3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P211433:  view genomic region     (about GC identifiers)

Start:
211,431,719 bp from pter      End:
211,489,727 bp from pter
Size:
58,009 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RCOR3_HUMAN, Q9P2K3 (See protein sequence)
Recommended Name: REST corepressor 3  
Size: 495 amino acids; 55581 Da
Sequence caution: Sequence=BAA92581.1; Type=Erroneous initiation;
Secondary accessions: B3KYA2 B4DYY7 Q5VT47 Q7L9I5 Q8N5U3 Q9NV83
Alternative splicing: 4 isoforms:  Q9P2K3-1   Q9P2K3-2   Q9P2K3-3   Q9P2K3-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RCOR3: NX_Q9P2K3

Explore proteomics data for RCOR3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys20, Lys325
  • Modification sites at PhosphoSitePlus

  • See RCOR3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001129695.1  NP_001129696.2  NP_001129697.1  NP_060724.1  

    ENSEMBL proteins: 
     ENSP00000436057   ENSP00000436838   ENSP00000355973   ENSP00000398558   ENSP00000432779  
     ENSP00000413929   ENSP00000434605   ENSP00000355972   ENSP00000433441   ENSP00000437048  
     ENSP00000434181  

    RCOR3 Human Recombinant Protein Products:

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    Novus Biologicals RCOR3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RCOR3

     
    Search eBioscience for Proteins for RCOR3 

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    Search for Antibodies for RCOR3 at Abcam
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    LSBio Antibodies in human, mouse, rat for RCOR3

    RCOR3 Assay Products:

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    Cloud-Clone Corp. ELISAs for RCOR3
    Cloud-Clone Corp. CLIAs for RCOR3
    Search eBioscience for ELISAs for RCOR3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR017884 SANT_dom
     IPR001005 SANT/Myb
     IPR000949 ELM2_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9P2K3

    ProtoNet protein and cluster: Q9P2K3

    UniProtKB/Swiss-Prot: RCOR3_HUMAN, Q9P2K3
    Similarity: Belongs to the CoREST family
    Similarity: Contains 1 ELM2 domain
    Similarity: Contains 2 SANT domains


    Find genes that share domains with RCOR3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RCOR3_HUMAN, Q9P2K3
    Function: May act as a component of a corepressor complex that represses transcription (Potential)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0005515protein binding IPI16189514
         
    Find genes that share ontologies with RCOR3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RCOR3:
     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RCOR3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RCOR3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RCOR3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RCOR3

    miRNA
    Products:
        
    miRTarBase miRNAs that target RCOR3:
    hsa-let-7e-5p (MIRT051445)

    Block miRNA regulation of human, mouse, rat RCOR3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RCOR3 (see all 45):
    hsa-miR-21* hsa-miR-136 hsa-miR-15a hsa-miR-128 hsa-miR-200a hsa-miR-30d hsa-miR-500a hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidRCOR3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RCOR3
    Predesigned siRNA for gene silencing in human, mouse, rat RCOR3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 4): RCOR3 (NM_001136224)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RCOR3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RCOR3

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RCOR3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCOR3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RCOR3_HUMAN, Q9P2K3: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with RCOR3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RCOR3
    Interactions:

        Search GeneGlobe Interaction Network for RCOR3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for RCOR3 (Q9P2K31, 2, 3 ENSP000004139294) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRT15P190121, 2, 3, ENSP000002540434EBI-743428,EBI-739566 MINT-66856 I2D: score=6 STRING: ENSP00000254043
    CEP70Q8NHQ12, 3, ENSP000002649824MINT-66342 I2D: score=5 STRING: ENSP00000264982
    NINLQ9Y2I62, 3, ENSP000002788864MINT-68109 I2D: score=5 STRING: ENSP00000278886
    GSE1Q146871, 3, ENSP000002534584EBI-743428,EBI-372619 I2D: score=4 STRING: ENSP00000253458
    NECAB2Q7Z6G32, 3, ENSP000003074494MINT-67388 I2D: score=4 STRING: ENSP00000307449
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with RCOR3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RCOR3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RCOR3 gene (4 alternative transcripts): 
    NM_001136223.1  NM_001136224.2  NM_001136225.1  NM_018254.3  

    Unigene Cluster for RCOR3:

    REST corepressor 3
    Hs.356399  [show with all ESTs]
    Unigene Representative Sequence: NM_001136223
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000534478 ENST00000533469 ENST00000367006 ENST00000452621(uc001hie.3)
    ENST00000528926(uc010psv.1) ENST00000419091 ENST00000528408 ENST00000472734
    ENST00000529572 ENST00000367005(uc010psw.2 uc001hif.3 uc001hig.3 uc009xcz.3)
    ENST00000534460 ENST00000529763 ENST00000485186 ENST00000486666 ENST00000528066
    ENST00000526255
    miRNA
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    Block miRNA regulation of human, mouse, rat RCOR3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RCOR3 (see all 45):
    hsa-miR-21* hsa-miR-136 hsa-miR-15a hsa-miR-128 hsa-miR-200a hsa-miR-30d hsa-miR-500a hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidRCOR3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RCOR3
    Predesigned siRNA for gene silencing in human, mouse, rat RCOR3
    Clone
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    OriGene clones in human, mouse for RCOR3 (see all 22)
    OriGene ORF clones in mouse, rat for RCOR3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): RCOR3 (NM_001136224)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RCOR3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RCOR3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RCOR3
    OriGene qSTAR qPCR primer pairs in human, mouse for RCOR3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RCOR3
      QuantiTect SYBR Green Assays in human, mouse, rat RCOR3
      QuantiFast Probe-based Assays in human, mouse, rat RCOR3

    Additional mRNA sequence: 

    AB037764.1 AK001738.1 AK057001.1 AK125810.1 AK131312.1 AK302664.1 AK311644.1 BC031608.1 

    13 DOTS entries:

    DT.446461  DT.100791231  DT.100742228  DT.99929041  DT.100791227  DT.40126075  DT.100791226  DT.437592 
    DT.100698394  DT.121458754  DT.121458771  DT.121458794  DT.65284646 

    Selected AceView cDNA sequences (see all 185):

    AI653139 BM722908 AK131312 AW051317 BI964143 AA398057 BM126872 BF196302 
    BC031608 AW021273 BX956434 AU133327 CR621031 BM697780 BQ010823 AW237171 
    BF197963 BQ448539 H88945 AI811045 AK001738 BM718325 BU741914 AA044128 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RCOR3 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b ·
    SP1:              -           -           -     -     -                                                           -           -     -           -     -         
    SP2:                          -           -     -     -                                                           -           -     -           -     -         
    SP3:              -           -           -     -     -                                                           -           -     -           -     -     -   
    SP4:              -                       -     -     -                                                                                                         
    SP5:              -           -           -     -     -                                                                                                         

    ExUns: 15c · 15d ^ 16a · 16b · 16c
    SP1:                              
    SP2:  -     -                     
    SP3:  -     -                     
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for RCOR3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RCOR3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATATAGTGA
    RCOR3 Expression
    About this image


    RCOR3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    RCOR3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RCOR3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.356399
        Custom PCR Arrays for RCOR3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RCOR3
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    QuantiFast Probe-based Assays in human, mouse, rat RCOR3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCOR3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RCOR3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rcor35 REST corepressor 3   --   1 (97.23 cM) 192100459 
    chicken
    (Gallus gallus)
    Aves RCOR36
    REST corepressor 3
    93(a)
    1 ↔ 1
    3(21628366-21650478)
    lizard
    (Anolis carolinensis)
    Reptilia RCOR36
    REST corepressor 3
    80(a)
    1 ↔ 1
    1(237824268-237849252)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rcor31 REST corepressor 3 78.4(n)
    83.71(a)
      779496  XM_004914768.1  XP_004914825.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rcor31 REST corepressor 3 70.72(n)
    77.38(a)
      563808  NM_001045029.1  NP_001038494.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CoRest6
    CoRest
    21(a)
    1 → many
    X(19415962-19424929)
    worm
    (Caenorhabditis elegans)
    Secernentea rcor-16
    spr-16
    Protein SPR-1 (spr-1) mRNA, complete cds
    15(a)
    13(a)
    many ↔ many
    many ↔ many
    I(17483-26781) WBGene00022278
    V(8126663-8129352) WBGene00005006


    ENSEMBL Gene Tree for RCOR3 (if available)
    TreeFam Gene Tree for RCOR3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RCOR3 gene
    RCOR22  RCOR12  
    4 SIMAP similar genes for RCOR3 using alignment to 8 protein entries:     RCOR3_HUMAN (see all proteins):
    RCOR1    RCOR2    FAM138C    KIAA1651

    Find genes that share paralogs with RCOR3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RCOR3 (see all 1107)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs354260131,2
    C,F--211430728(+) TTCTTC/TTCCTA 3 -- us2k110Minor allele frequency- T:0.46NA WA CSA EA 372
    rs802057871,2
    C,F--211430781(+) TGCTCG/AAATGG 3 -- us2k12Minor allele frequency- A:0.04NA EA 240
    rs1166348871,2
    F--211430809(+) GGTTTT/GACTAA 3 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1864101991,2
    --211430851(+) TCCAAC/TGTTTT 3 -- us2k10--------
    rs1897100841,2
    --211430870(+) ATCTAC/TATGCA 3 -- us2k10--------
    rs1411219781,2
    --211430954(+) CAGAGC/TGAGGA 3 -- us2k10--------
    rs67007471,2
    C,F,A,H--211431105(+) ATTTCA/CTTTGG 3 -- us2k123Minor allele frequency- C:0.40NS EA NA WA CSA 2348
    rs1451667641,2
    --211431116(+) CCAGGA/GCATTC 3 -- us2k10--------
    rs1475828221,2
    --211431129(+) TCCTTG/TTAGGA 3 -- us2k10--------
    rs747147291,2
    C,F--211431263(+) AGACTA/CTCTCT 3 -- us2k12Minor allele frequency- C:0.04NA EA 240

    HapMap Linkage Disequilibrium report for RCOR3 (211431719 - 211489727 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RCOR3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv159013CNV Loss16902084
    esv6409CNV Gain19470904

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with RCOR3           About GenesLikeMe

    Genetic Association Database (GAD): RCOR3
    Human Genome Epidemiology (HuGE) Navigator: RCOR3 (1 document)

    Export disorders for RCOR3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RCOR3 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with RCOR3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    7. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. (PubMed id 21258344)1 Bantscheff M....Drewes G. (Nat. Biotechnol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55758 HGNC: 25594 AceView: RCOR3 Ensembl:ENSG00000117625 euGenes: HUgn55758
    ECgene: RCOR3 H-InvDB: RCOR3

    (According to HUGE)
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    HUGE: KIAA1343

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RCOR3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RCOR3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RCOR3 gene:
    Search GeneIP for patents involving RCOR3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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