Aliases for RCN1 Gene
External Ids for RCN1 Gene
Previous Symbols for RCN1 Gene
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]
GeneCards Summary for RCN1 Gene
RCN1 (Reticulocalbin 1, EF-Hand Calcium Binding Domain) is a Protein Coding gene. Diseases associated with RCN1 include prostate cancer and wagr syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CALU.
UniProtKB/Swiss-Prot for RCN1 Gene
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment