Aliases for RCN1 Gene
External Ids for RCN1 Gene
Previous HGNC Symbols for RCN1 Gene
Previous GeneCards Identifiers for RCN1 Gene
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]
GeneCards Summary for RCN1 Gene
RCN1 (Reticulocalbin 1) is a Protein Coding gene. Diseases associated with RCN1 include nephrogenic systemic fibrosis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CALU.
UniProtKB/Swiss-Prot for RCN1 Gene
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.