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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RCL1 Gene

protein-coding   GIFtS: 53
GCID: GC09P004782

RNA Terminal Phosphate Cyclase-Like 1

Microbiology & Infectious Diseases Congress
  Search for RCL1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RNA Terminal Phosphate Cyclase-Like 11 2     RNA 3'-Terminal Phosphate Cyclase-Like Protein2
RNAC2 3     RNA Cyclase Homolog2
RPCL12 3     RPC23
2310040A02Rik2     RTC23

External Ids:    HGNC: 176871   Entrez Gene: 101712   Ensembl: ENSG000001201587   OMIM: 6114055   UniProtKB: Q9Y2P83   

Export aliases for RCL1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RCL1 Gene: 
RCL1 (RNA terminal phosphate cyclase-like 1) is a protein-coding gene. GO annotations related to this gene include RNA-3'-phosphate cyclase activity. An important paralog of this gene is RTCA.

UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8
Function: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA
processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity)

Gene Wiki entry for RCL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008413.18  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RCL1 gene promoter:
         NF-1/L   NF-YA   NF-YC   CBF-C   CBF-B   CBF-A   CP1A   CP1C   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRCL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RCL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RCL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.1-p23   Ensembl cytogenetic band:  9p24.1   HGNC cytogenetic band: 9p24.1-p23

RCL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RCL1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P004782:  view genomic region     (about GC identifiers)

Start:
4,792,834 bp from pter      End:
4,885,917 bp from pter
Size:
93,084 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8 (See protein sequence)
Recommended Name: RNA 3'-terminal phosphate cyclase-like protein  
Size: 373 amino acids; 40843 Da
Subcellular location: Nucleus, nucleolus (By similarity)
Sequence caution: Sequence=AAD32456.1; Type=Frameshift; Positions=13, 58;
Secondary accessions: D3DRI2 Q5VYW9 Q9H9D0 Q9NY00 Q9P044

Explore the universe of human proteins at neXtProt for RCL1: NX_Q9Y2P8

Explore proteomics data for RCL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y2P8

  • RCL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RCL1 Protein Expression
    REFSEQ proteins: NP_005763.3  
    ENSEMBL proteins: 
     ENSP00000371169   ENSP00000371151   ENSP00000412000   ENSP00000371149   ENSP00000371147  
     ENSP00000413381   ENSP00000388096  

    Human Recombinant Protein Products for RCL1: 
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    Novus Biologicals RCL1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RCL1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus NAS--

    RCL1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for RCL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR013791 RNA3'-term_phos_cycl_insert
     IPR023797 RNA3'_phos_cyclase_dom
     IPR016443 RNA3'_term_phos_cyc_type_2
     IPR020719 RNA3'_term_phos_cycl-like_CS
     IPR000228 RNA3'_term_phos_cyc

    Graphical View of Domain Structure for InterPro Entry Q9Y2P8

    ProtoNet protein and cluster: Q9Y2P8

    1 Blocks protein domain: IPB000228 _term_cycl

    UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8
    Similarity: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily


    RCL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RCL1_HUMAN, Q9Y2P8
    Function: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA
    processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0003963RNA-3'-phosphate cyclase activity NAS10790377
         
    RCL1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RCL1:
     Nuclear 40S maturation defects  Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RCL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RCL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RCL1 
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    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate RCL1:
    hsa-miR-511 hsa-miR-3690 hsa-miR-4254 hsa-miR-133a hsa-miR-4252 hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidRCL1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCL1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RCL1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for RCL1):
        Ribosome biogenesis in eukaryotes


    RCL1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RCL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/27 Interacting proteins for RCL1 (ENSP000003711694) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BMS1ENSP000003636424STRING: ENSP00000363642
    BYSLENSP000002303404STRING: ENSP00000230340
    GAR1ENSP000002267964STRING: ENSP00000226796
    HDGFENSP000003571894STRING: ENSP00000357189
    NOP58ENSP000002642794STRING: ENSP00000264279
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing IEA--
    GO:0008150biological_process ND--
    GO:0042254ribosome biogenesis IEA--

    RCL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RCL1

    Search CenterWatch for drugs/clinical trials and news about RCL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RCL1 gene: 
    NM_005772.3  

    Unigene Cluster for RCL1:

    RNA terminal phosphate cyclase-like 1
    Hs.194121  [show with all ESTs]
    Unigene Representative Sequence: NM_005772
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381750(uc003zis.2 uc010mhl.1) ENST00000381732 ENST00000442869
    ENST00000473230 ENST00000381730 ENST00000381728 ENST00000441844 ENST00000445485(uc003ziv.1)
    ENST00000448872
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate RCL1:
    hsa-miR-511 hsa-miR-3690 hsa-miR-4254 hsa-miR-133a hsa-miR-4252 hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidRCL1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for RCL1
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RCL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RCL1
    Sirion Biotech Customized lentivirus for stable overexpression of RCL1 
                         Customized lentivirus expression plasmids for stable overexpression of RCL1 
    Primer
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    OriGene qPCR primer pairs and template standards for RCL1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RCL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RCL1

    Additional mRNA sequence: 

    AF067172.1 AF161456.1 AJ276894.1 AK022904.1 AK225872.1 BC001025.2 EF553527.1 

    15 DOTS entries:

    DT.443376  DT.91761856  DT.100773507  DT.40131888  DT.121207796  DT.100773513  DT.121207800  DT.40246277 
    DT.97858875  DT.100024239  DT.121207786  DT.91761858  DT.95169187  DT.95169191  DT.87046986 

    24/202 AceView cDNA sequences (see all 202):

    BG257505 AV650770 CR613074 BE796777 AV650762 BI914339 BM547331 AV650261 
    BE795353 AV650527 AV650831 AJ276894 BQ009374 AL545511 BQ642949 BM824835 
    AI479714 AI688431 BQ883684 CR612665 BQ055897 BI827154 CR600925 BQ225993 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for RCL1 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b
    SP1:                                            -                 -           -     -                 -     -                 -                           
    SP2:                                            -     -     -     -           -     -                 -     -                 -                           
    SP3:                                                              -           -     -                                                                     
    SP4:                                            -                 -     -     -     -     -     -     -     -     -     -     -     -     -               
    SP5:                                            -     -     -     -     -     -     -     -     -     -                       -                           


    ECgene alternative splicing isoforms for RCL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RCL1 expression in normal human tissues (normalized intensities)      RCL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RCL1 Expression
    About this image


    RCL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Adipose (Muscoskeletal System)
             HyStem+BMP4-induced 7SMOO32 cells
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Blood (Hematopoietic System)

     -- (Gastrointestinal Tract)
             visceral organ/oral region/gland   

    See RCL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RCL1

    SOURCE GeneReport for Unigene cluster: Hs.194121
        SABiosciences Custom PCR Arrays for RCL1
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RCL1 gene from 10/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rcl11 , 5 RNA terminal phosphate cyclase-like 11, 5 88.56(n)1
    97.05(a)1
      19 (23.61 cM)5
    590281  NM_021525.21  NP_067500.11 
     291013755 
    chicken
    (Gallus gallus)
    Aves RCL11 RNA terminal phosphate cyclase-like 1 77.51(n)
    86.18(a)
      427222  XM_424808.3  XP_424808.1 
    lizard
    (Anolis carolinensis)
    Reptilia RCL16
    RNA terminal phosphate cyclase-like 1
    85(a)
    1 ↔ 1
    2(52118715-52148406)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC531712 similar to RNA cyclase homolog 74.5(n)    BC045026.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.69492 Transcribed sequence with moderate similarity to protein more 76.56(n)    57060986 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rtc11 CG11130-PA 56.85(n)
    55.14(a)
      32338  NM_132691.3  NP_572919.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK1127.51 Protein ZK1127.5 53.08(n)
    48.37(a)
      174151  NM_063044.4  NP_495445.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RCL1(YOL010W)4
    RCL11
    Subunit of U3-containing 90S preribosome processome more4
    Rcl1p1
    48.62(n)1
    38.75(a)1
      15(307938-309041)4
    8541521, 4  NP_014633.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G221001 RNA 3'-terminal phosphate cyclase-like protein 50.61(n)
    47.04(a)
      832271  NM_147891.3  NP_680196.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g08337001 hypothetical protein 51.79(n)
    47.46(a)
      4334688  NM_001058346.1  NP_001051811.1 


    ENSEMBL Gene Tree for RCL1 (if available)
    TreeFam Gene Tree for RCL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RCL1 gene
    RTCA2  

    RCL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RCL1
    PGOHUM00000237016


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2005 SNPs in RCL1 are shown (see all 2005)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1909035481,2
    --4790848(+) GGATCA/TAACAA 1 -- us2k10--------
    rs1390706031,2
    C--4790874(+) CATGG-/AAAATA 1 -- us2k10--------
    rs1831422681,2
    C--4790877(+) TGGAAA/CTAGAG 1 -- us2k10--------
    rs1161414311,2
    F--4790921(+) TAGAGG/CGGGTG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs109747851,2
    C,F,A--4791012(+) AGGTGT/ACTGTA 1 -- us2k12Minor allele frequency- A:0.06WA NA 238
    rs1411838851,2
    --4791130(+) TTCAGA/GATGTG 1 -- us2k10--------
    rs1491143571,2
    --4791219(+) AAATT-/AAAAAA 1 -- us2k10--------
    rs1166362791,2
    F--4791250(+) GACCCA/GGAATA 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1866987491,2
    --4791254(+) CAGAAC/TAGCCA 1 -- us2k10--------
    rs1469341141,2
    --4791299(+) AATCAC/TATTAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RCL1 (4792834 - 4885917 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RCL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2738158CNV Deletion23290073
    nsv6459CNV Insertion18451855
    nsv824824CNV Loss20364138
    nsv892131CNV Loss21882294
    nsv892133CNV Gain21882294
    nsv892132CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RCL1 for disorders           About MalaCards
    OMIM gene information: 611405    OMIM disorders: --


    RCL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RCL1
    Human Genome Epidemiology (HuGE) Navigator: RCL1 (1 document)

    Export disorders for RCL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RCL1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with RCL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (PubMed id 19862010)1, 4 Ganesh S.K....Lin J.P. (2009)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis. (PubMed id 10790377)1, 2 Billy E.... Filipowicz W. (2000)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    8. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. (PubMed id 23263863)1 Li J....Sleiman P.M. (2013)
    9. Seventy-five genetic loci influencing the human red bl ood cell. (PubMed id 23222517)1 van der Harst P....Chambers J.C. (2012)
    10. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10171 HGNC: 17687 AceView: RCL1 Ensembl:ENSG00000120158 euGenes: HUgn10171
    ECgene: RCL1 Kegg: 10171 H-InvDB: RCL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RCL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RCL1 gene:
    Search GeneIP for patents involving RCL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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