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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RCL1 Gene

protein-coding GIFtS: 52
GCID: GC09P004782

RNA terminal phosphate cyclase-like 1

Explore 1 disease affiliated with
RCL1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
RNA Terminal Phosphate Cyclase-Like 1¹ ²		RNA 3'-Terminal Phosphate Cyclase-Like Protein²
RNAC¹ ² ³		RNA Cyclase Homolog²
RPCL1¹ ² ³		RPC2³
2310040A02Rik²		RTC2³

External Ids:	HGNC: 17687¹	Entrez Gene: 10171²	Ensembl: ENSG00000120158⁷	OMIM: 611405⁵	UniProtKB: Q9Y2P8³

Export aliases for RCL1 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8

Function: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA

processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity)

Gene Wiki entry for RCL1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008413.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RCL1 gene promoter:
NF-1/L NF-YA NF-YC CBF-C CBF-B CBF-A CP1A CP1C NF-Y CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RCL1 promoter sequence

Search SABiosciences Chromatin IP Primers for RCL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RCL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.1-p23 Ensembl cytogenetic band: 9p24.1 HGNC cytogenetic band: 9p24.1-p23

RCL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RCL1 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P004782: view genomic region (about GC identifiers)

Start:	4,792,834 bp from pter	End:	4,861,064 bp from pter
Size:	68,231 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8 (See protein sequence)

Recommended Name: RNA 3'-terminal phosphate cyclase-like protein

Size: 373 amino acids; 40843 Da

Subcellular location: Nucleus, nucleolus (By similarity)

Sequence caution: Sequence=AAD32456.1; Type=Frameshift; Positions=13, 58;

Secondary accessions: D3DRI2 Q5VYW9 Q9H9D0 Q9NY00 Q9P044

Explore the universe of human proteins at neXtProt for RCL1: NX_Q9Y2P8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y2P8

RCL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_005763.3

ENSEMBL proteins:

ENSP00000371169 ENSP00000371151 ENSP00000412000 ENSP00000371149 ENSP00000371147

ENSP00000413381 ENSP00000388096

Human Recombinant Protein Products for RCL1:

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	Uscn Proteins for RCL1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005730	nucleolus	NAS	--

RCL1 for ontologies About GeneDecksing

RCL1 Antibody Products:

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	Uscn ELISAs and CLIAs for RCL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RCL1 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR023797 RNA3'_phos_cyclase_dom

IPR016443 RNA3'_term_phos_cyc_type_2

IPR013796 RNA3'_term_phos_cycl_insert

IPR020719 RNA3'_term_phos_cycl-like_CS

IPR000228 RNA3'_term_phos_cyc

Graphical View of Domain Structure for InterPro Entry Q9Y2P8

ProtoNet protein and cluster: Q9Y2P8

1 Blocks protein family: IPB000228 _term_cycl

UniProtKB/Swiss-Prot: RCL1_HUMAN, Q9Y2P8

Similarity: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: RCL1_HUMAN, Q9Y2P8

Function: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA

processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003824	catalytic activity	--	--
GO:0003963	RNA-3'-phosphate cyclase activity	NAS	10790377

RCL1 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for RCL1:

Nuclear 40S maturation defects

Nucleolar pre-40S maturation d

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RCL1

miRNA Products:		OriGene 3'-UTR Clone: RCL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RCL1
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate RCL1:
		hsa-miR-511 hsa-miR-3690 hsa-miR-4254 hsa-miR-133a hsa-miR-4252 hsa-miR-133b
		SwitchGear 3'UTR luciferase reporter plasmid: RCL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCL1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Ribosome biogenesis in eukaryotes

Ribosome biogenesis in eukaryotes

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for RCL1):

Ribosome biogenesis in eukaryotes

RCL1 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RCL1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/27 Interacting proteins for RCL1 (ENSP00000371169⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 27)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BMS1	ENSP00000363642⁴	STRING: ENSP00000363642
BYSL	ENSP00000230340⁴	STRING: ENSP00000230340
GAR1	ENSP00000226796⁴	STRING: ENSP00000226796
HDGF	ENSP00000357189⁴	STRING: ENSP00000357189
NOP58	ENSP00000264279⁴	STRING: ENSP00000264279

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006396	RNA processing	IEA	--
GO:0008150	biological_process	ND	--
GO:0042254	ribosome biogenesis	IEA	--

RCL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RCL1
Search CenterWatch for drugs/clinical trials and news about RCL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RCL1 gene:

NM_005772.3

Unigene Cluster for RCL1:

RNA terminal phosphate cyclase-like 1

Hs.194121 [show with all ESTs]

Unigene Representative Sequence: NM_005772

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000381750(uc003zis.2 uc010mhl.1) ENST00000381732 ENST00000442869

ENST00000473230 ENST00000381730 ENST00000381728 ENST00000441844 ENST00000448872

miRNA Products:		OriGene 3'-UTR Clone: RCL1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RCL1
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate RCL1:
		hsa-miR-511 hsa-miR-3690 hsa-miR-4254 hsa-miR-133a hsa-miR-4252 hsa-miR-133b
		SwitchGear 3'UTR luciferase reporter plasmid: RCL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RCL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RCL1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Additional cDNA sequence:

AF067172.1 AF161456.1 AJ276894.1 AK022904.1 AK225872.1 BC001025.2 EF553527.1

15 DOTS entries:

DT.443376 DT.91761856 DT.100773507 DT.40131888 DT.121207796 DT.100773513 DT.121207800 DT.40246277

DT.97858875 DT.100024239 DT.121207786 DT.91761858 DT.95169187 DT.95169191 DT.87046986

24/202 AceView cDNA sequences (see all 202):

BQ225993 CB068595 BP376439 BQ059299 BM541289 CR623784 BC001025 BQ065949

CR625779 AA344149 AI479714 BE795353 BQ933532 BQ883684 BM563256 AI688431

BM824835 BQ642949 AL545511 AJ276894 BQ009374 AV650527 AV650261 AV650831

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for RCL1 (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	·	1g	^	2	^	3	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	·	6c	^	7	^	8a	·	8b	^	9a	·	9b	^	10a	·	10b	^	11a	·	11b
SP1:															-						-				-		-						-		-						-
SP2:															-		-		-		-				-		-						-		-						-
SP3:																					-				-		-
SP4:															-						-		-		-		-		-		-		-		-		-		-		-		-		-
SP5:															-		-		-		-		-		-		-		-		-		-								-

ECgene alternative splicing isoforms for RCL1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RCL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

RCL1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Liver

Liver Lobule

Liver

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RCL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RCL1

SOURCE GeneReport for Unigene cluster: Hs.194121

SABiosciences Custom PCR Arrays for RCL1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RCL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for RCL1 gene from 11/36 species (see all 36) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Rcl1^{1 , 5}	RNA terminal phosphate cyclase-like 1^{1, 5}	88.56(n)¹ 97.05(a)¹		19 (23.61 cM)⁵ 59028¹ NM_021525.2¹ NP_067500.1¹ 29101375⁵
chicken (Gallus gallus)	Aves	RCL1¹	RNA terminal phosphate cyclase-like 1	77.51(n) 86.18(a)		427222 XM_424808.3 XP_424808.1
lizard (Anolis carolinensis)	Reptilia	RCL1⁶	--	84(a)	1 ↔ 1	2(52119609-52147739)
African clawed frog (Xenopus laevis)	Amphibia	MGC53171²	similar to RNA cyclase homolog	74.5(n)		BC045026.1
zebrafish (Danio rerio)	Actinopterygii	Dr.6949²	Transcribed sequence with moderate similarity to protein more	76.56(n)		57060986
fruit fly (Drosophila melanogaster)	Insecta	Rtc1¹	CG11130-PA	56.85(n) 55.14(a)		32338 NM_132691.3 NP_572919.1
worm (Caenorhabditis elegans)	Secernentea	ZK1127.5¹	Protein ZK1127.5	53.08(n) 48.37(a)		174151 NM_063044.4 NP_495445.2
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	RCL1(YOL010W)⁴ RCL1¹	Subunit of U3-containing 90S preribosome processome more⁴ Rcl1p¹	48.62(n)¹ 38.75(a)¹		15(307938-309041)⁴ 854152^{1, 4} NP_014633.1^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G22100¹	RNA 3'-terminal phosphate cyclase-like protein	50.61(n) 47.04(a)		832271 NM_147891.3 NP_680196.1
rice (Oryza sativa)	Liliopsida	Os03g0833700¹	hypothetical protein	51.79(n) 47.46(a)		4334688 NM_001058346.1 NP_001051811.1

ENSEMBL Gene Tree for RCL1 (if available)
TreeFam Gene Tree for RCL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RCL1 gene

RTCA²

RCL1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for RCL1
PGOHUM00000237016

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs190903548^1,2		--	4790848(+)	`GGATCA/TAACAA`	1	--	us2k¹		0	--	--	--	--
rs139070603^1,2	C	--	4790874(+)	`CATGG-/AAAATA`	1	--	us2k¹		0	--	--	--	--
rs183142268^1,2		--	4790877(+)	`TGGAAA/CTAGAG`	1	--	us2k¹		0	--	--	--	--
rs116141431^1,2	F	--	4790921(+)	`TAGAGG/CGGGTG`	1	--	us2k¹		1		WA	118
rs10974785^1,2	F,A	--	4791012(+)	`AGGTGT/ACTGTA`	1	--	us2k¹		2		WA NA	238
rs141183885^1,2		--	4791130(+)	`TTCAGA/GATGTG`	1	--	us2k¹		0	--	--	--	--
rs149114357^1,2		--	4791219(+)	`AAATT-/AAAAAA`	1	--	us2k¹		0	--	--	--	--
rs116636279^1,2	F	--	4791250(+)	`GACCCA/GGAATA`	1	--	us2k¹		1		WA	118
rs186698749^1,2		--	4791254(+)	`CAGAAC/TAGCCA`	1	--	us2k¹		0	--	--	--	--
rs146934114^1,2		--	4791299(+)	`AATCAC/TATTAC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RCL1 (4792834 - 4861064 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RCL1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RCL1

DNA2.0 Custom Variant and Variant Library Synthesis for RCL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RCL1 for disorders           About GeneDecksing

OMIM gene information: 611405    OMIM disorders: --

1 disease for RCL1:    About MalaCards

malaria

Human Genome Epidemiology (HuGE) Navigator: RCL1 (1 document)

Export disorders for RCL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RCL1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with RCL1)

Utopia: connect your pdf to the dynamic
world of online information

DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)^{1, 2} Humphray S.J.... Dunham I. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis. (PubMed id 10790377)^{1, 2} Billy E.... Filipowicz W. (2000)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2} Zhang Q.-H.... Chen Z. (2000)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)¹ Zhao J....Yang P. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
New gene functions in megakaryopoiesis and platelet fo rmation. (PubMed id 22139419)¹ Gieger C....Soranzo N. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10171	HGNC: 17687	AceView: RCL1	Ensembl:ENSG00000120158	euGenes: HUgn10171
ECgene: RCL1	Kegg: 10171	H-InvDB: RCL1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RCL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RCL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RCL1 gene:
Search GeneIP for patents involving RCL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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RCL1 Gene

RNA terminal phosphate cyclase-like 1

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RCL1 Gene

RNA terminal phosphate cyclase-like 1

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