Aliases for RCC1 Gene
External Ids for RCC1 Gene
Previous HGNC Symbols for RCC1 Gene
Previous GeneCards Identifiers for RCC1 Gene
GeneCards Summary for RCC1 Gene
RCC1 (Regulator Of Chromosome Condensation 1) is a Protein Coding gene. Among its related pathways are Disease and Cytoskeletal Signaling. GO annotations related to this gene include chromatin binding and nucleosomal DNA binding. An important paralog of this gene is RCBTB2.
UniProtKB/Swiss-Prot for RCC1 Gene
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.