Aliases for RBP4 Gene
External Ids for RBP4 Gene
Previous GeneCards Identifiers for RBP4 Gene
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for RBP4 Gene
RBP4 (Retinol Binding Protein 4) is a Protein Coding gene. Diseases associated with RBP4 include retinal dystrophy, iris coloboma, and comedogenic acne syndrome and microphthalmia, isolated, with coloboma 10. Among its related pathways are Signaling by GPCR and Metabolism. GO annotations related to this gene include protein heterodimerization activity and retinol binding.
UniProtKB/Swiss-Prot for RBP4 Gene
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.