Aliases for RBP4 Gene
External Ids for RBP4 Gene
Previous GeneCards Identifiers for RBP4 Gene
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for RBP4 Gene
RBP4 (Retinol Binding Protein 4) is a Protein Coding gene. Diseases associated with RBP4 include Retinal Dystrophy, Iris Coloboma, And Comedogenic Acne Syndrome and Microphthalmia, Isolated, With Coloboma 10. Among its related pathways are the visual cycle I (vertebrates) and Retinoid cycle disease events. GO annotations related to this gene include protein heterodimerization activity and retinol binding.
UniProtKB/Swiss-Prot for RBP4 Gene
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.