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Aliases for RBMY1C Gene

Aliases for RBMY1C Gene

  • RNA Binding Motif Protein, Y-Linked, Family 1, Member C 2 3
  • RNA Binding Motif Protein, Y Chromosome, Family 1, Member C 2

External Ids for RBMY1C Gene

Previous GeneCards Identifiers for RBMY1C Gene

  • GC0YP022827
  • GC0YM022871
  • GC0YP022011
  • GC0YP022083
  • GC0YM022438
  • GC0YP023673

Summaries for RBMY1C Gene

GeneCards Summary for RBMY1C Gene

RBMY1C (RNA Binding Motif Protein, Y-Linked, Family 1, Member C) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding.

UniProtKB/Swiss-Prot for RBMY1C Gene

  • RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBMY1C Gene

Genomics for RBMY1C Gene

Genomic Location for RBMY1C Gene

Orientation:
Unknown strand

Genomic View for RBMY1C Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for RBMY1C Gene

Proteins for RBMY1C Gene

  • Protein details for RBMY1C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0DJD4-RBY1C_HUMAN
    Recommended name:
    RNA-binding motif protein, Y chromosome, family 1 member C
    Protein Accession:
    P0DJD4
    Secondary Accessions:
    • Q15376
    • Q15377
    • Q15414
    • Q6NSB5
    • Q86VU6
    • Q8NHR0

    Protein attributes for RBMY1C Gene

    Size:
    496 amino acids
    Molecular mass:
    55784 Da
    Quaternary structure:
    • Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.
    Miscellaneous:
    • The RBMY1 proteins are encoded by repeated regions of the Y chromosome, mostly within the AZFb region. The exact number of functional copies is unclear and may vary between individuals, and some of them may represent pseudogenes. The proteins are very similar, which makes the characterization of each protein difficult. Thus, most experiments do not discriminate between the different members. One can therefore suppose that reported interactions with a RBMY1 protein involve all the proteins

neXtProt entry for RBMY1C Gene

Proteomics data for RBMY1C Gene at MOPED

Post-translational modifications for RBMY1C Gene

No Post-translational modifications

No data available for DME Specific Peptides for RBMY1C Gene

Domains for RBMY1C Gene

Gene Families for RBMY1C Gene

HGNC:
  • RBM :RNA binding motif (RRM) containing

Protein Domains for RBMY1C Gene

Suggested Antigen Peptide Sequences for RBMY1C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0DJD4

UniProtKB/Swiss-Prot:

RBY1C_HUMAN :
  • P0DJD4
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with RBMY1C: view

Function for RBMY1C Gene

Molecular function for RBMY1C Gene

GENATLAS Biochemistry:
RNA binding motif protein,Y chromosome,family 1,member C,in a AZF deleted region
UniProtKB/Swiss-Prot Function:
RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs

Gene Ontology (GO) - Molecular Function for RBMY1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with RBMY1C: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RBMY1C Gene

Localization for RBMY1C Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBMY1C Gene

Gene Ontology (GO) - Cellular Components for RBMY1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with RBMY1C: view

No data available for Subcellular locations from COMPARTMENTS for RBMY1C Gene

Pathways for RBMY1C Gene

SuperPathways for RBMY1C Gene

No Data Available

Interacting Proteins for RBMY1C Gene

Gene Ontology (GO) - Biological Process for RBMY1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006397 mRNA processing IEA --
GO:0008380 RNA splicing IEA --
genes like me logo Genes that share ontologies with RBMY1C: view

No data available for Pathways by source for RBMY1C Gene

Transcripts for RBMY1C Gene

Alternative Splicing Database (ASD) splice patterns (SP) for RBMY1C Gene

No ASD Table

Relevant External Links for RBMY1C Gene

ECgene alternative splicing isoforms for
RBMY1C

No data available for mRNA/cDNA for RBMY1C Gene

Expression for RBMY1C Gene

Protein differential expression in normal tissues for RBMY1C Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for RBMY1C Gene

mRNA Expression by UniProt/SwissProt for RBMY1C Gene

P0DJD4-RBY1C_HUMAN
Tissue specificity: Testis-specific

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for RBMY1C Gene

Orthologs for RBMY1C Gene

No data available for Orthologs and Evolution for RBMY1C Gene

Paralogs for RBMY1C Gene

Selected SIMAP similar genes for RBMY1C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RBMY1C: view

No data available for Paralogs for RBMY1C Gene

Variants for RBMY1C Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for RBMY1C Gene

Disorders for RBMY1C Gene

No disorders were found for RBMY1C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RBMY1C Gene

Publications for RBMY1C Gene

  1. Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene. (PMID: 9598316) Chai N.-N. … Yen P.H. (Genomics 1998) 2 3 4
  2. RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing. (PMID: 10749975) Venables J.P. … Eperon E.C. (Hum. Mol. Genet. 2000) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. Expression of RBM in the nuclei of human germ cells is dependent on a critical region of the Y chromosome long arm. (PMID: 9108067) Elliott D.J. … Cooke H. (Proc. Natl. Acad. Sci. U.S.A. 1997) 4
  5. T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA- binding protein implicated in spermatogenesis. (PMID: 10332027) Venables J.P. … Eperon I.C. (Hum. Mol. Genet. 1999) 4

Products for RBMY1C Gene

Sources for RBMY1C Gene

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