RBMXL3 Gene
protein-coding GIFtS: 34
GCID: GC0XP114423
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RNA binding motif protein, X-linked-like 3(Previous name: chromosome X open reading frame 55 )
(Previous symbol: CXorf55)
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Aliases
for RBMXL3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RNA Binding Motif Protein, X-Linked-Like 31 2 | | CXorf551 2 3 | | FLJ402491 | | Chromosome X Open Reading Frame 551 | | RNA-Binding Motif Protein, X-Linked-Like-32 |
Export aliases for RBMXL3 gene to outside databasesPrevious GC identifers: GC0XP114330 GC0XP104008 |
Summaries
for RBMXL3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RBMXL3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_028405.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RBMXL3 gene promoter:
Sox5 Elk-1 HNF-1A C/EBPalpha Pax-3 POU2F1 POU2F1a HNF-1 IRF-7A Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for RBMXL3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMXL3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq23 Ensembl cytogenetic band: Xq23 HGNC cytogenetic band: Xq23RBMXL3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP114423: view genomic region
(about GC identifiers)
Start:
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114,423,963 bp from pter |
End:
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114,427,431 bp from pter |
Size:
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3,469 bases |
Orientation:
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plus strand |
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Proteins
for RBMXL3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RMXL3_HUMAN, Q8N7X1 (See
protein sequence)Recommended Name: RNA-binding motif protein, X-linked-like-3 Size: 1067 amino acids; 114938 Da
Caution: Encoded in intron of the LRCH2 gene
Secondary accessions: B4DXC0Explore the universe of human proteins at neXtProt for RBMXL3: NX_Q8N7X1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N7X1
RBMXL3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001138818.1
ENSEMBL proteins: ENSP00000417451
Human Recombinant Protein Products for RBMXL3:
RBMXL3 Antibody Products:
Assay Products for RBMXL3: |
Protein
Domains /
Families
for RBMXL3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RBMXL3 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N7X1ProtoNet protein and cluster: Q8N7X1 UniProtKB/Swiss-Prot: RMXL3_HUMAN, Q8N7X1Similarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for RBMXL3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0003723 | RNA binding |
IEA | -- |
RBMXL3 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RBMXL3 (NM_001145346) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBMXL3 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RBMXL3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMXL3 |
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Pathways & Interactions
for RBMXL3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBMXL3
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for RBMXL3 (ENSP000004174514) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for RBMXL3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RBMXL3
Search CenterWatch for drugs/clinical trials and news about RBMXL3 / RMXL3
|
Transcripts
for RBMXL3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RBMXL3 gene (2 alternative transcripts): NM_152425.1 NM_001145346.1 Unigene Cluster for RBMXL3: RNA binding motif protein, X-linked-like 3 Hs.376008 [show with all ESTs]Unigene Representative Sequence: AK3019041 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000424776(uc011mte.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RBMXL3 (NM_001145346) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBMXL3 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RBMXL3 |
Additional cDNA sequence: AK097568.1 AK301904.1 2 DOTS entries: DT.121306185 DT.100008408 3 AceView cDNA sequences: AK097568 NM_152425 BF887114
GeneLoc Exon Structure
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Expression
for RBMXL3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RBMXL3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTCTTACAG
About this image
See RBMXL3 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.376008
SABiosciences Custom PCR Arrays for RBMXL3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMXL3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RBMXL3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMXL3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMXL3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMXL3 |
Orthologs
for RBMXL3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RBMXL3 gene from 6/15 species (see all 15) About this table
ENSEMBL Gene Tree for RBMXL3 (if available)
TreeFam Gene Tree for RBMXL3 (if available) |
Paralogs
for RBMXL3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RBMXL3 gene
- RBMY1E2 RBMY1J2 RBMY1F2 RBMXL22 TRA2B2 RBMY1B2 RBMXL12 RBMY1A12
- CIRBP2 RBM32 TRA2A2 RBMX2 RBMY1D2
9 SIMAP similar genes for RBMXL3 using alignment to 1 protein entry: RMXL3_HUMAN:RBM HNRNPA1 RBM3 RBMXL2 CIRBP RBM38
RBMXL1 RBMX SFRS3
RBMXL3 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RBMXL3
PGOHUM00000241362
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Genomic Variants
for RBMXL3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RBMXL3
3 CNVs: 83683 7758 96900
1 Indel: 83684 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMXL3 |
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Disorders
/ Diseases
for RBMXL3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RBMXL3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RBMXL3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RBMXL3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (2011)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
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External Searches for RBMXL3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RBMXL3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing RBMXL3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RBMXL3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RBMXL3 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for RBMXL3 gene:
Search GeneIP for patents involving RBMXL3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RBMXL3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RBMXL3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBMXL3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMXL3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RBMXL3 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMXL3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBMXL3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMXL3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMXL3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBMXL3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMXL3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMXL3 |
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 | | | RBMXL3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMXL3 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RBMXL3 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RBMXL3 |
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