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Aliases for RBMXL3 Gene

Aliases for RBMXL3 Gene

  • RNA Binding Motif Protein, X-Linked-Like 3 2 3
  • CXorf55 3 4
  • RNA-Binding Motif Protein, X-Linked-Like-3 3
  • Chromosome X Open Reading Frame 55 2

External Ids for RBMXL3 Gene

Previous Symbols for RBMXL3 Gene

  • CXorf55

Summaries for RBMXL3 Gene

GeneCards Summary for RBMXL3 Gene

RBMXL3 (RNA Binding Motif Protein, X-Linked-Like 3) is a Protein Coding gene. Among its related pathways are Spliceosome. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBMXL1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBMXL3 Gene

Genomics for RBMXL3 Gene

Genomic Location for RBMXL3 Gene

Start:
115,189,400 bp from pter
End:
115,192,868 bp from pter
Size:
3,469 bases
Orientation:
Plus strand

Genomic View for RBMXL3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RBMXL3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBMXL3 Gene

Regulatory Elements for RBMXL3 Gene

Proteins for RBMXL3 Gene

  • Protein details for RBMXL3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7X1-RMXL3_HUMAN
    Recommended name:
    RNA-binding motif protein, X-linked-like-3
    Protein Accession:
    Q8N7X1
    Secondary Accessions:
    • B4DXC0

    Protein attributes for RBMXL3 Gene

    Size:
    1067 amino acids
    Molecular mass:
    114938 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBMXL3 Gene

Proteomics data for RBMXL3 Gene at MOPED

Post-translational modifications for RBMXL3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBMXL3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBMXL3 Gene

Domains for RBMXL3 Gene

Gene Families for RBMXL3 Gene

HGNC:
  • RBM :RNA binding motif (RRM) containing

Protein Domains for RBMXL3 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RMXL3_HUMAN
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.:
    • Q8N7X1
genes like me logo Genes that share domains with RBMXL3: view

Function for RBMXL3 Gene

Gene Ontology (GO) - Molecular Function for RBMXL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with RBMXL3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RBMXL3 Gene

Localization for RBMXL3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RBMXL3 Gene COMPARTMENTS Subcellular localization image for RBMXL3 gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for RBMXL3 Gene

Pathways for RBMXL3 Gene

SuperPathways for RBMXL3 Gene

Superpath Contained pathways
1 Spliceosome
genes like me logo Genes that share pathways with RBMXL3: view

Pathways by source for RBMXL3 Gene

1 KEGG pathway for RBMXL3 Gene

Interacting Proteins for RBMXL3 Gene

Gene Ontology (GO) - Biological Process for RBMXL3 Gene

None

Transcripts for RBMXL3 Gene

mRNA/cDNA for RBMXL3 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RBMXL3 Gene

RNA binding motif protein, X-linked-like 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBMXL3 Gene

No ASD Table

Relevant External Links for RBMXL3 Gene

GeneLoc Exon Structure for
RBMXL3
ECgene alternative splicing isoforms for
RBMXL3

Expression for RBMXL3 Gene

mRNA expression in normal human tissues for RBMXL3 Gene

mRNA differential expression in normal tissues according to GTEx for RBMXL3 Gene

This gene is overexpressed in Testis (49.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RBMXL3 Gene

SOURCE GeneReport for Unigene cluster for RBMXL3 Gene Hs.376008

genes like me logo Genes that share expressions with RBMXL3: view

Orthologs for RBMXL3 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBMXL3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RBMXL3 37
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RBMX 37
  • 64 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Rbmxl2 37
  • 64 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 54 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 53 (a)
OneToMany
chicken
(Gallus gallus)
Aves RBMX 37
  • 57 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 56 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii rbmx 37
  • 48 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta tra2 37
  • 18 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rsp-8 37
  • 18 (a)
OneToMany
Species with no ortholog for RBMXL3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RBMXL3 Gene

ENSEMBL:
Gene Tree for RBMXL3 (if available)
TreeFam:
Gene Tree for RBMXL3 (if available)

Paralogs for RBMXL3 Gene

Paralogs for RBMXL3 Gene

Selected SIMAP similar genes for RBMXL3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for RBMXL3 Gene

genes like me logo Genes that share paralogs with RBMXL3: view

Variants for RBMXL3 Gene

Structural Variations from Database of Genomic Variants (DGV) for RBMXL3 Gene

Variant ID Type Subtype PubMed ID
esv33994 CNV Gain+Loss 17666407
nsv520351 CNV Gain 19592680

Relevant External Links for RBMXL3 Gene

HapMap Linkage Disequilibrium report
RBMXL3

No data available for Sequence variations from dbSNP and Humsavar for RBMXL3 Gene

Disorders for RBMXL3 Gene

No disorders were found for RBMXL3 Gene.

No data available for UniProtKB/Swiss-Prot for RBMXL3 Gene

Publications for RBMXL3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PMID: 22178446) Lopitz-Otsoa F. … Rodriguez M.S. (J Proteomics 2012) 3
  5. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PMID: 22678362) Stehling O. … Lill R. (Science 2012) 3

Products for RBMXL3 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate RBMXL3
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RBMXL3
    • Block miRNA regulation of RBMXL3 using miScript Target Protectors

    Sources for RBMXL3 Gene

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