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Aliases for RBMXL1 Gene

Aliases for RBMXL1 Gene

  • RNA Binding Motif Protein, X-Linked-Like 1 2 3
  • Heterogeneous Nuclear Ribonucleoprotein G-Like 1 3 4
  • RNA Binding Motif Protein, X-Linked-Like-1 3
  • Kynurenine Aminotransferase III 2
  • RBM1 3

External Ids for RBMXL1 Gene

Previous GeneCards Identifiers for RBMXL1 Gene

  • GC01M089116
  • GC01M089218
  • GC00U930610
  • GC01M089446
  • GC01M087562

Summaries for RBMXL1 Gene

Entrez Gene Summary for RBMXL1 Gene

  • This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]

GeneCards Summary for RBMXL1 Gene

RBMXL1 (RNA Binding Motif Protein, X-Linked-Like 1) is a Protein Coding gene. Among its related pathways are Spliceosome. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is CIRBP.

UniProtKB/Swiss-Prot for RBMXL1 Gene

  • RNA-binding protein which may be involved in pre-mRNA splicing.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBMXL1 Gene

Genomics for RBMXL1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RBMXL1 Gene

88,979,456 bp from pter
88,992,960 bp from pter
13,505 bases
Minus strand

Genomic View for RBMXL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RBMXL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBMXL1 Gene

No data available for Regulatory Elements for RBMXL1 Gene

Proteins for RBMXL1 Gene

  • Protein details for RBMXL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA binding motif protein, X-linked-like-1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for RBMXL1 Gene

    390 amino acids
    Molecular mass:
    42142 Da
    Quaternary structure:
    No Data Available
    • According to some authors, RBMXL1 is a RBMX retrogene on chromosome X which is likely to be functional.

neXtProt entry for RBMXL1 Gene

Proteomics data for RBMXL1 Gene at MOPED

Post-translational modifications for RBMXL1 Gene

  • Ubiquitination at Lys9, Lys63, and Lys217
  • Modification sites at PhosphoSitePlus

Other Protein References for RBMXL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBMXL1 Gene

Domains for RBMXL1 Gene

Gene Families for RBMXL1 Gene

Protein Domains for RBMXL1 Gene

Suggested Antigen Peptide Sequences for RBMXL1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 RRM (RNA recognition motif) domain.
  • Contains 1 RRM (RNA recognition motif) domain.
genes like me logo Genes that share domains with RBMXL1: view

Function for RBMXL1 Gene

Molecular function for RBMXL1 Gene

UniProtKB/Swiss-Prot Function:
RNA-binding protein which may be involved in pre-mRNA splicing.

Gene Ontology (GO) - Molecular Function for RBMXL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
GO:0003727 single-stranded RNA binding --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with RBMXL1: view

Phenotypes for RBMXL1 Gene

GenomeRNAi human phenotypes for RBMXL1:
genes like me logo Genes that share phenotypes with RBMXL1: view

Animal Model Products

miRNA for RBMXL1 Gene

miRTarBase miRNAs that target RBMXL1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RBMXL1 Gene

Localization for RBMXL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBMXL1 Gene

Subcellular locations from

Jensen Localization Image for RBMXL1 Gene COMPARTMENTS Subcellular localization image for RBMXL1 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for RBMXL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005681 spliceosomal complex --
GO:0030529 ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with RBMXL1: view

Pathways for RBMXL1 Gene

SuperPathways for RBMXL1 Gene

Superpath Contained pathways
1 Spliceosome
genes like me logo Genes that share pathways with RBMXL1: view

Pathways by source for RBMXL1 Gene

1 KEGG pathway for RBMXL1 Gene

Gene Ontology (GO) - Biological Process for RBMXL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006376 mRNA splice site selection --
GO:0006397 mRNA processing IEA --
GO:0008380 RNA splicing IEA --
GO:0045893 positive regulation of transcription, DNA-templated --
genes like me logo Genes that share ontologies with RBMXL1: view

Transcripts for RBMXL1 Gene

mRNA/cDNA for RBMXL1 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RBMXL1 Gene

No ASD Table

Relevant External Links for RBMXL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBMXL1 Gene

mRNA expression in normal human tissues for RBMXL1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBMXL1 Gene

genes like me logo Genes that share expressions with RBMXL1: view

Expression partners for RBMXL1 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBMXL1 Gene

Orthologs for RBMXL1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBMXL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Rattus norvegicus)
Mammalia Rbmxl1 35
  • 86.72 (n)
  • 90.11 (a)
(Mus musculus)
Mammalia Rbmxl1 16
Rbmx 36
  • 94 (a)
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 88 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 85 (a)
(Pan troglodytes)
Mammalia RBMX 36
  • 100 (a)
(Gallus gallus)
Aves RBMX 36
  • 89 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 88 (a)
(Danio rerio)
Actinopterygii rbmx 36
  • 72 (a)
fruit fly
(Drosophila melanogaster)
Insecta tra2 36
  • 20 (a)
(Caenorhabditis elegans)
Secernentea rsp-8 36
  • 23 (a)
Species with no ortholog for RBMXL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RBMXL1 Gene

Gene Tree for RBMXL1 (if available)
Gene Tree for RBMXL1 (if available)

Paralogs for RBMXL1 Gene

Paralogs for RBMXL1 Gene

(10) SIMAP similar genes for RBMXL1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RBMXL1: view

Variants for RBMXL1 Gene

Structural Variations from Database of Genomic Variants (DGV) for RBMXL1 Gene

Variant ID Type Subtype PubMed ID
dgv68e1 CNV Complex 17122850
esv7403 CNV Gain 19470904

Relevant External Links for RBMXL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for RBMXL1 Gene

Disorders for RBMXL1 Gene

No disorders were found for RBMXL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RBMXL1 Gene

Publications for RBMXL1 Gene

  1. Emergence of young human genes after a burst of retroposition in primates. (PMID: 16201836) Marques A.C. … Kaessmann H. (PLoS Biol. 2005) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. (PMID: 19165527) Martins-de-Souza D. … Turck C.W. (Eur Arch Psychiatry Clin Neurosci 2009) 3
  4. Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease. (PMID: 10441733) Yu P. … Tagle D.A. (Mamm. Genome 1999) 2
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for RBMXL1 Gene

Sources for RBMXL1 Gene

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