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Aliases for RBMX2 Gene

Aliases for RBMX2 Gene

  • RNA Binding Motif Protein, X-Linked 2 2 3 5
  • CGI-79 3
  • Snu17 3

External Ids for RBMX2 Gene

Previous GeneCards Identifiers for RBMX2 Gene

  • GC0XP128242
  • GC0XP129261
  • GC0XP129363
  • GC0XP129535
  • GC0XP118931

Summaries for RBMX2 Gene

GeneCards Summary for RBMX2 Gene

RBMX2 (RNA Binding Motif Protein, X-Linked 2) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBMX2 Gene

Genomics for RBMX2 Gene

Regulatory Elements for RBMX2 Gene

Enhancers for RBMX2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RBMX2 on UCSC Golden Path with GeneCards custom track

Promoters for RBMX2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RBMX2 on UCSC Golden Path with GeneCards custom track

Genomic Location for RBMX2 Gene

130,401,969 bp from pter
130,413,343 bp from pter
11,375 bases
Plus strand

Genomic View for RBMX2 Gene

Genes around RBMX2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBMX2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBMX2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBMX2 Gene

Proteins for RBMX2 Gene

  • Protein details for RBMX2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding motif protein, X-linked 2
    Protein Accession:
    Secondary Accessions:
    • A8K9Z0
    • Q5JY82
    • Q9Y3I8

    Protein attributes for RBMX2 Gene

    322 amino acids
    Molecular mass:
    37336 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RBMX2 Gene

Proteomics data for RBMX2 Gene at MOPED

Post-translational modifications for RBMX2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RBMX2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RBMX2 Gene

Domains & Families for RBMX2 Gene

Gene Families for RBMX2 Gene

Protein Domains for RBMX2 Gene

Suggested Antigen Peptide Sequences for RBMX2 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 RRM (RNA recognition motif) domain.
  • Belongs to the IST3 family.
  • Contains 1 RRM (RNA recognition motif) domain.
  • Belongs to the IST3 family.
genes like me logo Genes that share domains with RBMX2: view

Function for RBMX2 Gene

Gene Ontology (GO) - Molecular Function for RBMX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0000384 contributes_to first spliceosomal transesterification activity IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IBA --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with RBMX2: view

Phenotypes for RBMX2 Gene

genes like me logo Genes that share phenotypes with RBMX2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RBMX2 Gene

Localization for RBMX2 Gene

Subcellular locations from

Jensen Localization Image for RBMX2 Gene COMPARTMENTS Subcellular localization image for RBMX2 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for RBMX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IBA --
genes like me logo Genes that share ontologies with RBMX2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RBMX2 Gene

Pathways & Interactions for RBMX2 Gene

SuperPathways for RBMX2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBMX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome IBA --
genes like me logo Genes that share ontologies with RBMX2: view

No data available for Pathways by source and SIGNOR curated interactions for RBMX2 Gene

Drugs & Compounds for RBMX2 Gene

No Compound Related Data Available

Transcripts for RBMX2 Gene

Unigene Clusters for RBMX2 Gene

RNA binding motif protein, X-linked 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RBMX2 Gene

No ASD Table

Relevant External Links for RBMX2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBMX2 Gene

mRNA expression in normal human tissues for RBMX2 Gene

Protein differential expression in normal tissues from HIPED for RBMX2 Gene

This gene is overexpressed in Adrenal (25.3), Peripheral blood mononuclear cells (22.7), and Lung (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RBMX2 Gene

SOURCE GeneReport for Unigene cluster for RBMX2 Gene Hs.740515

genes like me logo Genes that share expression patterns with RBMX2: view

Protein tissue co-expression partners for RBMX2 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RBMX2 Gene

Orthologs for RBMX2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RBMX2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RBMX2 35
  • 85.02 (n)
  • 80.06 (a)
-- 36
  • 74 (a)
RBMX2 36
  • 74 (a)
(Canis familiaris)
Mammalia RBMX2 35
  • 83.23 (n)
  • 77.64 (a)
RBMX2 36
  • 78 (a)
(Mus musculus)
Mammalia Rbmx2 35
  • 78.97 (n)
  • 75.27 (a)
Rbmx2 16
Rbmx2 36
  • 71 (a)
(Pan troglodytes)
Mammalia RBMX2 35
  • 98.03 (n)
  • 97.47 (a)
RBMX2 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Rbmx2 35
  • 81.12 (n)
  • 78.14 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
-- 36
  • 68 (a)
-- 36
  • 51 (a)
(Ornithorhynchus anatinus)
Mammalia RBMX2 36
  • 47 (a)
(Gallus gallus)
Aves RBMX2 36
  • 49 (a)
(Anolis carolinensis)
Reptilia RBMX2 36
  • 58 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC64376 35
(Danio rerio)
Actinopterygii rbmx2 36
  • 35 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000977 35
  • 64.23 (n)
  • 66.42 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10466 35
  • 64.96 (n)
  • 66.42 (a)
CG10466 36
  • 62 (a)
(Caenorhabditis elegans)
Secernentea C30B5.4 36
  • 37 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes IST3 36
  • 44 (a)
(Oryza sativa)
Liliopsida Os.7367 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2920 36
  • 31 (a)
Species with no ortholog for RBMX2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RBMX2 Gene

Gene Tree for RBMX2 (if available)
Gene Tree for RBMX2 (if available)

Paralogs for RBMX2 Gene

(3) SIMAP similar genes for RBMX2 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with RBMX2: view

No data available for Paralogs for RBMX2 Gene

Variants for RBMX2 Gene

Sequence variations from dbSNP and Humsavar for RBMX2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs5977266 - 130,412,739(+) AGGGC(A/G)TAGTT reference, missense
rs747721162 -- 130,411,313(+) TGAGG(A/G)CTGTC intron-variant
rs747815603 -- 130,412,849(+) ACTGA(A/G)GACTT utr-variant-3-prime
rs747953293 -- 130,403,788(+) ATGTG(G/T)TTTTC intron-variant
rs748007472 -- 130,402,319(+) TGGCC(A/G)ATAAG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RBMX2 Gene

Variant ID Type Subtype PubMed ID
nsv528290 CNV Gain 19592680
esv2017730 CNV Deletion 18987734
esv2440853 CNV Deletion 19546169
esv2740470 CNV Deletion 23290073

Variation tolerance for RBMX2 Gene

Residual Variation Intolerance Score: 41% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.67; 14.32% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RBMX2 Gene

Disorders for RBMX2 Gene

Relevant External Links for RBMX2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RBMX2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBMX2 Gene

Publications for RBMX2 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. Dynamic protein-protein interaction wiring of the human spliceosome. (PMID: 22365833) Hegele A. … Stelzl U. (Mol. Cell 2012) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for RBMX2 Gene

Sources for RBMX2 Gene