RBMX2 Gene
protein-coding GIFtS: 46
GCID: GC0XP129535
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|
RNA binding motif protein, X-linked 2
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Aliases
for RBMX2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RNA Binding Motif Protein, X-Linked 21 2 | | CGI-791 2 | | RNA-Binding Motif Protein, X-Linked 22 |
Export aliases for RBMX2 gene to outside databasesPrevious GC identifers: GC0XP128242 GC0XP129261 GC0XP129363 GC0XP118931 |
Summaries
for RBMX2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RBMX2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011786.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RBMX2 gene promoter:
Max1 GR USF1 LHX3b/Lhx3b FOXD1 Ik-3 USF-1 LHX3a/Lhx3a GR-alpha MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for RBMX2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMX2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq26.1 Ensembl cytogenetic band: Xq26.1 HGNC cytogenetic band: Xq26.1RBMX2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP129535: view genomic region
(about GC identifiers)
Start:
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129,535,943 bp from pter |
End:
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129,547,317 bp from pter |
Size:
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11,375 bases |
Orientation:
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plus strand |
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Proteins
for RBMX2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RBMX2_HUMAN, Q9Y388 (See
protein sequence)Recommended Name: RNA-binding motif protein, X-linked 2 Size: 322 amino acids; 37336 Da
Secondary accessions: A8K9Z0 Q5JY82 Q9Y3I8Explore the universe of human proteins at neXtProt for RBMX2: NX_Q9Y388
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y388
RBMX2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057108.2
ENSEMBL proteins: ENSP00000339090 ENSP00000359985
Human Recombinant Protein Products for RBMX2:
RBMX2 Antibody Products:
Assay Products for RBMX2: |
Protein
Domains /
Families
for RBMX2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RBMX2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y388ProtoNet protein and cluster: Q9Y388 1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
UniProtKB/Swiss-Prot: RBMX2_HUMAN, Q9Y388Similarity: Belongs to the IST3 familySimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for RBMX2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0003723 | RNA binding |
IEA | -- |
RBMX2 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for RBMX2:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RBMX2 (NM_016024) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBMX2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMX2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMX2 |
|
Pathways & Interactions
for RBMX2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RBMX2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/14 Interacting proteins for RBMX2 (Q9Y3882 ENSP000003390904) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
|
Drugs & Compounds
for RBMX2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RBMX2
Search CenterWatch for drugs/clinical trials and news about RBMX2
|
Transcripts
for RBMX2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RBMX2 gene: NM_016024.2 Unigene Cluster for RBMX2: RNA binding motif protein, X-linked 2 Hs.740515 [show with all ESTs]Unigene Representative Sequence: AF1518374 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000305536(uc004evt.3) ENST00000469953 ENST00000370947 ENST00000487274
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RBMX2 (NM_016024) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RBMX2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMX2 |
Additional cDNA sequence: AF078865.1 AF151837.1 AK292855.1 AL050405.1 BC003676.1 BC010036.2 BC012345.1 BC033750.1 BC040433.1 BC050707.1 BC063517.1 BC105582.1 7 DOTS entries: DT.101982924 DT.40313190 DT.121308968 DT.70103491 DT.100829541 DT.92426306 DT.121308949 24/159 AceView cDNA sequences (see all 159): C02473 AI858736 BC010036 AI090665 BC050707 AI419267 AW593805 BC063517 BI753148 AI879604 BX376663 BQ018634 BF718426 BF476468 BC033750 CA446793 BU688491 BM695435 AL050405 AI917337 BE672261 CA310096 BM920835 AI672755
GeneLoc Exon Structure
|
Expression
for RBMX2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RBMX2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCAAACCTT
About this image
See RBMX2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RBMX2
SOURCE GeneReport for Unigene cluster: Hs.740515
SABiosciences Custom PCR Arrays for RBMX2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMX2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RBMX2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMX2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMX2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMX2 |
Orthologs
for RBMX2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RBMX2 gene from 9/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RBMX26 |
Uncharacterized protein |
72(a) |
1 ↔ 1 |
4(1553805-1555944) |
lizard
(Anolis carolinensis) |
Reptilia |
RBMX26 |
-- |
57(a) |
1 ↔ 1 |
GL343451.1(321449-324262) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC643762 |
hypothetical protein MGC64376 |
73.38(n) |
|
BC056844.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
rbmx21 |
RNA binding motif protein, X-linked 2 |
57.73(n)
57.41(a) |
|
553240 NM_001025166.1 NP_001020337.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG104661 |
CG10466 |
62.55(n)
62.34(a) |
|
35268 NM_136159.2 NP_610003.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
C30B5.41 |
Protein C30B5.4 |
55.86(n)
56.94(a) |
|
183040 NM_062836.1 NP_495237.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
IST31 |
Ist3p |
52.59(n)
50.37(a) |
|
854821 NP_012270.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G471201 |
RNA-binding motif protein, X-linked 2 |
46.86(n)
39.62(a) |
|
823865 NM_114579.2 NP_190296.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.73672 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
71.18(n) |
|
AK071472.1 |
ENSEMBL Gene Tree for RBMX2 (if available)
TreeFam Gene Tree for RBMX2 (if available) |
Paralogs
for RBMX2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RBMX2 gene
- ZCRB12
3 SIMAP similar genes for RBMX2 using alignment to 4 protein entries: RBMX2_HUMAN (see all proteins):ZCRB1 CSTF2 RBM38
RBMX2 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for RBMX2
PGOHUM00000244162 PGOHUM00000239035 PGOHUM00000251320 PGOHUM00000250852 PGOHUM00000241577
|
Genomic Variants
for RBMX2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RBMX2 (129535943 - 129547317 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RBMX2
1 CNV: 103277
1 Indel: 47765 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMX2 |
|
Disorders
/ Diseases
for RBMX2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RBMX2 for disorders About GeneDecksing
1  disease for RBMX2: About MalaCardsmalaria
Export disorders for RBMX2 gene to outside databases
|
Publications
for RBMX2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RBMX2 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with RBMX2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for RBMX2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RBMX2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RBMX2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RBMX2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RBMX2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RBMX2 gene:
Search GeneIP for patents involving RBMX2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RBMX2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RBMX2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBMX2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMX2 | | | OriGene Protein Over-expression Lysate for RBMX2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RBMX2 | | OriGene 3'-UTR Clone for RBMX2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMX2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBMX2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMX2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMX2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBMX2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMX2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMX2 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMX2 |
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