Aliases for RBMS3 Gene
External Ids for RBMS3 Gene
Previous GeneCards Identifiers for RBMS3 Gene
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
GeneCards Summary for RBMS3 Gene
RBMS3 (RNA Binding Motif, Single Stranded Interacting Protein 3) is a Protein Coding gene. Diseases associated with RBMS3 include osteonecrosis of the jaw and lung squamous cell carcinoma. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is PABPC1.
UniProtKB/Swiss-Prot for RBMS3 Gene
Binds poly(A) and poly(U) oligoribonucleotides.