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RBMS2 Gene

protein-coding   GIFtS: 50
GCID: GC12P056915

RNA Binding Motif, Single Stranded Interacting Protein 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RNA Binding Motif, Single Stranded Interacting Protein 21 2
Suppressor Of CDC2 With RNA-Binding Motif 32 3
SCR32 3
RNA-Binding Motif, Single-Stranded-Interacting Protein 22

External Ids:    HGNC: 99091   Entrez Gene: 59392   Ensembl: ENSG000000760677   OMIM: 6023875   UniProtKB: Q154343   

Export aliases for RBMS2 gene to outside databases

Previous GC identifers: GC12P056808 GC12P057140 GC12P056632 GC12P055202 GC12P053954


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RBMS2 Gene:
The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA.
These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS)
that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA
binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription,
cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13
mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2.
(provided by RefSeq, Jul 2008)

GeneCards Summary for RBMS2 Gene:
RBMS2 (RNA binding motif, single stranded interacting protein 2) is a protein-coding gene. Diseases associated with RBMS2 include pyelonephritis, and measles. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is PABPC1L.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RBMS2 gene promoter:
         E2F-4   E2F-3a   E2F-5   NCX/Ncx   CUTL1   E2F-2   E2F-1   Nkx6-1   E2F   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRBMS2 promoter sequence
   Search Chromatin IP Primers for RBMS2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RBMS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13.13

RBMS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBMS2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P056915:  view genomic region     (about GC identifiers)

Start:
56,915,609 bp from pter      End:
56,989,980 bp from pter
Size:
74,372 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RBMS2_HUMAN, Q15434 (See protein sequence)
Recommended Name: RNA-binding motif, single-stranded-interacting protein 2  
Size: 407 amino acids; 43959 Da
1 PDB 3D structure from and Proteopedia for RBMS2:
1X4E (3D)    

Explore the universe of human proteins at neXtProt for RBMS2: NX_Q15434

Explore proteomics data for RBMS2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RBMS2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002889.1  
    ENSEMBL proteins: 
     ENSP00000262031   ENSP00000447426   ENSP00000447699   ENSP00000450127   ENSP00000449678  
     ENSP00000443486  

    RBMS2 Human Recombinant Protein Products:

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    Novus Biologicals RBMS2 Protein
    Novus Biologicals RBMS2 Lysates
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for RBMS2

    RBMS2 Antibody Products:

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    Abcam antibodies for RBMS2
    Cloud-Clone Corp. Antibodies for RBMS2
    Search ThermoFisher Antibodies for RBMS2
    LSBio Antibodies in human, mouse, rat for RBMS2

    RBMS2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RBMS2
    Cloud-Clone Corp. CLIAs for RBMS2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q15434

    ProtoNet protein and cluster: Q15434

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: RBMS2_HUMAN, Q15434
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    RBMS2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding TAS8041632
    GO:0044822poly(A) RNA binding IDA--
         
    RBMS2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RBMS2:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RBMS2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RBMS2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RBMS2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RBMS2

    miRNA
    Products:
        
    miRTarBase miRNAs that target RBMS2:
    hsa-mir-18b-5p (MIRT042413), hsa-mir-484 (MIRT042145), hsa-mir-26b-5p (MIRT029628)

    Block miRNA regulation of human, mouse, rat RBMS2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBMS2 (see all 111):
    hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3916 hsa-miR-3161 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidRBMS2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RBMS2
    Predesigned siRNA for gene silencing in human, mouse, rat RBMS2

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for RBMS2

    Clone
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    OriGene clones in human, mouse for RBMS2 (see all 6)
    OriGene ORF clones in mouse, rat for RBMS2
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    GenScript: all cDNA clones in your preferred vector: RBMS2 (NM_002898)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBMS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMS2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RBMS2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMS2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RBMS2_HUMAN, Q15434: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1
    extracellular1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    RBMS2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RBMS2
    Interactions:

        Search GeneGlobe Interaction Network for RBMS2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for RBMS2 (Q154343 ENSP000002620314) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FAM69BQ5VUD63, ENSP000003607574I2D: score=4 STRING: ENSP00000360757
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing TAS8041632

    RBMS2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RBMS2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RBMS2 gene: 
    NM_002898.3  

    Unigene Cluster for RBMS2:

    RNA binding motif, single stranded interacting protein 2
    Hs.505729  [show with all ESTs]
    Unigene Representative Sequence: NM_002898
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262031(uc001sln.2 uc010sqp.1 uc010sqq.1 uc009zou.2)
    ENST00000552247 ENST00000551369 ENST00000552916 ENST00000549945 ENST00000550726
    ENST00000542360 ENST00000552228
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RBMS2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RBMS2 (see all 111):
    hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3916 hsa-miR-3161 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidRBMS2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RBMS2
    Predesigned siRNA for gene silencing in human, mouse, rat RBMS2
    Clone
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    OriGene clones in human, mouse for RBMS2 (see all 6)
    OriGene ORF clones in mouse, rat for RBMS2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RBMS2 (NM_002898)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBMS2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMS2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RBMS2
    OriGene qSTAR qPCR primer pairs in human, mouse for RBMS2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RBMS2
      QuantiTect SYBR Green Assays in human, mouse, rat RBMS2
      QuantiFast Probe-based Assays in human, mouse, rat RBMS2

    Additional mRNA sequence: 

    AK096412.1 AK097342.1 AK125252.1 AK293315.1 AK299580.1 AK304540.1 AK308885.1 BC027863.1 
    BC072679.1 D28483.1 

    17 DOTS entries:

    DT.100661007  DT.412524  DT.121178221  DT.97862246  DT.121178150  DT.121195334  DT.121178153  DT.101954208 
    DT.102834507  DT.40106044  DT.75183682  DT.92419984  DT.95158854  DT.95361281  DT.100838184  DT.40189574 
    DT.97818988 

    Selected AceView cDNA sequences (see all 294):

    CA941132 BX436318 AI375166 AW136451 NM_002898 AK097342 CD107953 AA347699 
    AA902806 BM763572 CR611083 BC027863 BX357396 D28483 AA436373 AI026117 
    CR612928 AA025963 CA434696 AI378325 BI772357 BX473954 CR597503 BQ711251 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RBMS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAAAAACAG
    RBMS2 Expression
    About this image


    RBMS2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Intermediate Mesoderm (Gastrulation Derivatives)
             Mesonephros
     
     Kidney (Urinary System)
             Metanephros
     
     Thyroid (Endocrine System)
    RBMS2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RBMS2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.505729
        Custom PCR Arrays for RBMS2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RBMS2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMS2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RBMS2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rbms21 , 5 RNA binding motif, single stranded interacting protein more1, 5 86.02(n)1
    88.13(a)1
      10 (76.41 cM)5
    565161  NM_019711.21  NP_062685.21 
     1281294705 
    chicken
    (Gallus gallus)
    Aves RBMS26
    RNA binding motif, single stranded interacting pro...
    62(a)
    1 ↔ 1
    AADN03018986.1(21-1042)
    lizard
    (Anolis carolinensis)
    Reptilia RBMS26
    RNA binding motif, single stranded interacting pro...
    82(a)
    1 ↔ 1
    2(93046636-93118956)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rbms21 RNA binding motif, single stranded interacting protein more 73.52(n)
    79.19(a)
      100495159  XM_004911893.1  XP_004911950.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rbms2a1 RNA binding motif, single stranded interacting protein more 71.87(n)
    75.96(a)
      378458  XM_005155662.1  XP_005155719.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta shep6
    alan shepard
    30(a)
    1 → many
    3L(5148921-5271044)
    worm
    (Caenorhabditis elegans)
    Secernentea R10E4.2b3 RNA recognition motif. (aka RRM, RBD,
    or RNP domain) more
    57(a)
    (best of 2)
      III(4349152-4351056)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PAB16
    Poly(A) binding protein, part of the 3'-end RNA-pr...
    13(a)
    1 → many
    V(510373-512106) YER165W


    ENSEMBL Gene Tree for RBMS2 (if available)
    TreeFam Gene Tree for RBMS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RBMS2 gene
    PABPC1L2  PABPC52  PABPC42  ELAVL12  PABPC4L2  ELAVL42  RBMS12  ELAVL32  
    RBMS32  PABPC32  ELAVL22  PABPC12  
    Selected SIMAP similar genes for RBMS2 using alignment to 6 protein entries:     RBMS2_HUMAN (see all proteins) (see all similar genes):
    AAMDC    CTSS    RPGRIP1    ACTR10    TMEM14B    RBMS1
    DCUN1D4    LYRM4    ZNF564    ZNF738    NF2    UTY
    ZNF212    RBMS3    AURA2    FKBP3    CNN2    ZNF554

    RBMS2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RBMS2
    PGOHUM00000239547


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RBMS2 (see all 1454)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs597152531,2
    C--56747593(+) AAAAA-/A/AAA 
            
    TATAT
    2 -- us2k1 cds10--------
    rs1385396141,2
    C--56913608(+) GACTT-/A/AAA 
            
    AAAAA
    1 -- cds10--------
    rs589951081,2
    C--56913616(+) AAAAAA/TATATA 1 -- us2k10--------
    rs672143401,2
    C--56913616(+) AAAAA-/TATATA 1 -- us2k11Minor allele frequency- T:0.00CSA 2
    rs2015712561,2
    C--56913620(+) ATATAA/TATATA 1 -- us2k10--------
    rs26579071,2
    A--56913639(-) CGCCCG/TGCCCA 1 -- us2k12Minor allele frequency- T:0.00NA 4
    rs26949181,2
    --56913646(+) GGCGCA/GGTGGC 1 -- us2k10--------
    rs1401032821,2
    C--56913832(+) AACCCA/GGGACG 1 -- us2k10--------
    rs1927203731,2
    --56913847(+) GGTTGC/TGGTGA 1 -- us2k10--------
    rs1458530511,2
    --56913872(+) ACTGCA/GCTCTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RBMS2 (56915609 - 56989980 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RBMS2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662220CNV Deletion23128226
    esv1272042CNV Insertion17803354
    nsv820140CNV Loss19587683
    nsv526706CNV Gain19592680
    nsv899106CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RBMS2
    DNA2.0 Custom Variant and Variant Library Synthesis for RBMS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602387    OMIM disorders: --

    6 diseases for RBMS2:    
    About MalaCards
    pyelonephritis    measles    amyotrophic lateral sclerosis    lateral sclerosis
    thyroiditis    endotheliitis


    RBMS2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RBMS2

    Export disorders for RBMS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RBMS2 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with RBMS2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. (PubMed id 8041632)1, 2, 3 Kanaoka Y. and Nojima H. (Nucleic Acids Res. 1994)
    2. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. (PubMed id 22479202)1, 4 Dastani Z....Kathiresan S. (PLoS Genet. 2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    8. Proteomic profiling of Myc-associated proteins. (PubMed id 21150319)1 Agrawal P....Sedivy J.M. (Cell Cycle 2010)
    9. Identification of long stress-induced non-coding transcripts that have altered expression in cancer. (PubMed id 20214974)1 Silva J.M....Smith D.I. (Genomics 2010)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5939 HGNC: 9909 AceView: RBMS2 Ensembl:ENSG00000076067 euGenes: HUgn5939
    ECgene: RBMS2 H-InvDB: RBMS2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RBMS2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RBMS2 gene:
    Search GeneIP for patents involving RBMS2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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