Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RBMS2 Gene

protein-coding GIFtS: 49
GCID: GC12P056915

RNA binding motif, single stranded interacting protein 2

Explore 3 diseases affiliated with
RBMS2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
RNA Binding Motif, Single Stranded Interacting Protein 2¹ ²
SCR3¹ ² ³
Suppressor Of CDC2 With RNA-Binding Motif 3² ³
RNA-Binding Motif, Single-Stranded-Interacting Protein 2²

External Ids:	HGNC: 9909¹	Entrez Gene: 5939²	Ensembl: ENSG00000076067⁷	OMIM: 602387⁵	UniProtKB: Q15434³

Export aliases for RBMS2 gene to outside databases

Previous GC identifers: GC12P056808 GC12P057140 GC12P056632 GC12P055202 GC12P053954

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RBMS2:

The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These

proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain

conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS

proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression

and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is

thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. (provided by RefSeq, Jul

2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RBMS2 gene promoter:
E2F-4 E2F-3a E2F-5 NCX/Ncx CUTL1 E2F-2 E2F-1 Nkx6-1 E2F NF-E2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RBMS2 promoter sequence

Search SABiosciences Chromatin IP Primers for RBMS2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMS2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13.13

RBMS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RBMS2 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12P056915: view genomic region (about GC identifiers)

Start:	56,915,609 bp from pter	End:	56,989,980 bp from pter
Size:	74,372 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RBMS2_HUMAN, Q15434 (See protein sequence)

Recommended Name: RNA-binding motif, single-stranded-interacting protein 2

Size: 407 amino acids; 43959 Da

Subcellular location: Nucleus (Potential)

1 PDB 3D structure from and Proteopedia for RBMS2:

1X4E (3D)

Explore the universe of human proteins at neXtProt for RBMS2: NX_Q15434

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q15434

RBMS2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_002889.1

ENSEMBL proteins:

ENSP00000262031 ENSP00000447426 ENSP00000447699 ENSP00000450127 ENSP00000449678

ENSP00000443486 ENSP00000440442

Human Recombinant Protein Products for RBMS2:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: RBMS2 OriGene Protein Over-expression Lysate: RBMS2 OriGene Custom Protein Services for RBMS2
	GenScript Custom Purified and Recombinant Proteins Services for RBMS2
	Novus Biologicals RBMS2 Protein Novus Biologicals RBMS2 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RBMS2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

RBMS2 for ontologies About GeneDecksing

RBMS2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for RBMS2
	GenScript Custom Superior Antibodies Services for RBMS2
	Novus Biologicals RBMS2 Antibodies
	Abcam antibodies for RBMS2
	Uscn Antibodies for RBMS2
	Search ThermoFisher Antibodies for RBMS2

Assay Products for RBMS2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RBMS2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RBMS2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RBMS2 for domains About GeneDecksing

2 InterPro domains/families:

IPR012677 Nucleotide-bd_a/b_plait

IPR000504 RRM_dom

Graphical View of Domain Structure for InterPro Entry Q15434

ProtoNet protein and cluster: Q15434

1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

UniProtKB/Swiss-Prot: RBMS2_HUMAN, Q15434

Similarity: Contains 2 RRM (RNA recognition motif) domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003676	nucleic acid binding	--	--
GO:0003723	RNA binding	IEA	--

RBMS2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for RBMS2:

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RBMS2

miRNA Products:		OriGene 3'-UTR Clone: RBMS2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBMS2
		8/111 QIAGEN miScript miRNA Assays for microRNAs that regulate RBMS2 (see all 111):
		hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3916 hsa-miR-3161 hsa-miR-93

		SwitchGear 3'UTR luciferase reporter plasmid: RBMS2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBMS2 (see all 7) OriGene shRNA RFP: RBMS2 OriGene siRNA: RBMS2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBMS2
		Sirion Biotech Custom design and validation of potent shRNA sequences against RBMS2

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for RBMS2
			Sirion Biotech Customized adenovirus for overexpression of RBMS2 Sirion Biotech Customized adenovirus for potent knockdown of RBMS2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RBMS2 (NM_002898)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBMS2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMS2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RBMS2
		Search LifeMap BioReagents cell lines for RBMS2
		Sirion Biotech Customized stable knockdown cell line services for RBMS2 Sirion Biotech Customized inducible knockdown cell line services for RBMS2 Sirion Biotech Customized stable overexpressing cell line services for RBMS2 Sirion Biotech Customized inducible overexpressing cell line services for RBMS2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMS2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RBMS2

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for RBMS2 (Q15434³ ENSP00000262031⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FAM69B	Q5VUD6³, ENSP00000360757⁴	I2D: score=4 STRING: ENSP00000360757
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006396	RNA processing	TAS	8041632

RBMS2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RBMS2
Search CenterWatch for drugs/clinical trials and news about RBMS2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RBMS2 gene:

NM_002898.3

Unigene Cluster for RBMS2:

RNA binding motif, single stranded interacting protein 2

Hs.505729 [show with all ESTs]

Unigene Representative Sequence: NM_002898

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000262031(uc001sln.2 uc010sqp.1 uc010sqq.1 uc009zou.2)

ENST00000552247 ENST00000551369 ENST00000552916 ENST00000549945 ENST00000550726

ENST00000542360 ENST00000545007 ENST00000552228

miRNA Products:		OriGene 3'-UTR Clone: RBMS2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RBMS2
		8/111 QIAGEN miScript miRNA Assays for microRNAs that regulate RBMS2 (see all 111):
		hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-1260b hsa-miR-519a hsa-miR-3916 hsa-miR-3161 hsa-miR-93

		SwitchGear 3'UTR luciferase reporter plasmid: RBMS2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBMS2 (see all 7) OriGene shRNA RFP: RBMS2 OriGene siRNA: RBMS2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBMS2
		Sirion Biotech Custom design and validation of potent shRNA sequences against RBMS2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RBMS2 (NM_002898)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RBMS2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMS2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMS2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RBMS2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMS2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMS2

Additional cDNA sequence:

AK096412.1 AK097342.1 AK125252.1 AK293315.1 AK299580.1 AK304540.1 AK308885.1 BC027863.1

BC072679.1 D28483.1

17 DOTS entries:

DT.100661007 DT.412524 DT.121178221 DT.97862246 DT.121178150 DT.121195334 DT.102834507 DT.121178153

DT.101954208 DT.40106044 DT.75183682 DT.92419984 DT.95158854 DT.95361281 DT.100838184 DT.40189574

DT.97818988

24/294 AceView cDNA sequences (see all 294):

AA410284 CR594007 AA374652 NM_002898 BX436318 AK097342 AW136451 CA941132

BX477949 C01838 D28483 AI026117 BM991183 AA347699 CR597503 AA025963

AI333353 AA292379 AA436373 BQ010177 BC027863 BI772357 BU069305 BQ711251

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RBMS2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAAAAACAG

About this image

RBMS2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Reproductive System

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RBMS2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RBMS2

SOURCE GeneReport for Unigene cluster: Hs.505729

SABiosciences Custom PCR Arrays for RBMS2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMS2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RBMS2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMS2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMS2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMS2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RBMS2 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	RBMS2⁶	--	78(a)	1 ↔ 1	2(93046642-93071913)
zebrafish (Danio rerio)	Actinopterygii	LOC559040¹	RNA-binding motif, single-stranded-interacting protein more	72.04(n) 76.47(a)		559040 XM_682340.5 XP_687432.5
fruit fly (Drosophila melanogaster)	Insecta	shep⁶	alan shepard	27(a)	1 → many	3L(5148921-5271044)
worm (Caenorhabditis elegans)	Secernentea	R10E4.2b³	RNA recognition motif. (aka RRM, RBD, or RNP domain) more	57(a) (best of 2)		III(4349152-4351056) --
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G47310⁶ FCA⁶	RNA binding / abscisic acid binding protein	8(a) 7(a)	many ↔ many many ↔ many	2(19423684-19427277) 4(9206597-9214825)
rice (Oryza sativa)	Liliopsida	FCA⁶	flowering time control protein FCA, putative, expr...	7(a)	1 → many	9(1789446-1798611)

ENSEMBL Gene Tree for RBMS2 (if available)
TreeFam Gene Tree for RBMS2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RBMS2 gene

PABPC1L² PABPC5² PABPC4² PABPC4L² ELAVL1² RBMS1² ELAVL4² ELAVL3²

RBMS3² PABPC3² ELAVL2² PABPC1L2B² PABPC1L2A² PUF60² PABPC1²

18/41 SIMAP similar genes for RBMS2 using alignment to 7 protein entries: RBMS2_HUMAN (see all proteins) (see all similar genes):

AAMDC RPGRIP1 ACTR10 TMEM14B RBMS1 DCUN1D4

LYRM4 ZNF564 NF2 RFXANK UTY RBMS3

ZDHHC20 ZNF212 AURA2 FKBP3 CNN2 ZNF554

RBMS2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for RBMS2
PGOHUM00000239547

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs58995108^1,2	C	--	56913616(+)	`AAAAAA/TATATA`	1	--	us2k¹		0	--	--	--	--
rs67214340^1,2	C	--	56913616(+)	`AAAAA-/TATATA`	1	--	us2k¹		1		CSA	2
rs2657907^1,2	A	--	56913639(-)	`CGCCCG/TGCCCA`	1	--	us2k¹		2		NA	4
rs2694918^1,2		--	56913646(+)	`GGCGCA/GGTGGC`	1	--	us2k¹		0	--	--	--	--
rs140103282^1,2		--	56913832(+)	`AACCCA/GGGACG`	1	--	us2k¹		0	--	--	--	--
rs192720373^1,2		--	56913847(+)	`GGTTGC/TGGTGA`	1	--	us2k¹		0	--	--	--	--
rs145853051^1,2		--	56913872(+)	`ACTGCA/GCTCTA`	1	--	us2k¹		0	--	--	--	--
rs184141228^1,2		--	56913886(+)	`TGGGCA/GACAGA`	1	--	us2k¹		0	--	--	--	--
rs2638287^1,2	C,F,A,H	--	56913902(+)	`ACTCTG/ATCTCA`	1	--	us2k¹		13		NS EA NA	1870
rs73329513^1,2	C,F	--	56914014(+)	`TCCCAC/TCCTTC`	1	--	us2k¹		5		WA CSA	125

HapMap Linkage Disequilibrium report for RBMS2 (56915609 - 56989980 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RBMS2
2 Indels: 39906 58581

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMS2

DNA2.0 Custom Variant and Variant Library Synthesis for RBMS2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RBMS2 for disorders           About GeneDecksing

OMIM gene information: 602387    OMIM disorders: --

3 diseases for RBMS2:    About MalaCards

pyelonephritis measles malaria

Export disorders for RBMS2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RBMS2 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with RBMS2)

Utopia: connect your pdf to the dynamic
world of online information

SCR: novel human suppresors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. (PubMed id 8041632)^{1, 2, 3} Kanaoka Y. and Nojima H. (1994)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. (PubMed id 22479202)¹ Dastani Z....Kathiresan S. (2012)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Identification of long stress-induced non-coding tran scripts that have altered expression in cancer. (PubMed id 20214974)¹ Silva J.M....Smith D.I. (2010)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)² Oppermann F.S.... Daub H. (2009)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)² Daub H.... Mann M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 5939	HGNC: 9909	AceView: RBMS2	Ensembl:ENSG00000076067	euGenes: HUgn5939
ECgene: RBMS2	H-InvDB: RBMS2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RBMS2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RBMS2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RBMS2 gene:
Search GeneIP for patents involving RBMS2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for RBMS2
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RBMS2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RBMS2
	OriGene Protein Over-expression Lysate for RBMS2		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for RBMS2		OriGene 3'-UTR Clone for RBMS2
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RBMS2
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for RBMS2		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RBMS2		OriGene Custom Protein Services for RBMS2
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RBMS2
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RBMS2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RBMS2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RBMS2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RBMS2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RBMS2

	GenScript Custom Purified and Recombinant Proteins Services for RBMS2		GenScript cDNA clones with any tag delivered in your preferred vector for RBMS2
	GenScript Custom Assay Services for RBMS2		GenScript Custom Superior Antibodies Services for RBMS2
	GenScript Custom overexpressing Cell Line Services for RBMS2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RBMS2 promoter
	Search Chromatin IP Primers for RBMS2
	RT² qPCR Primer Assay in human, mouse, rat RBMS2
	Search GNC Networks for RBMS2
	SABiosciences Custom PCR Arrays for RBMS2

Search Tocris compounds for RBMS2

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RBMS2 antibodies
	RBMS2 proteins
	RBMS2 lysates

	Antibodies for RBMS2
	See all of Abcam's Antibodies, Kits and Proteins for RBMS2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RBMS2 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RBMS2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RBMS2

	SwitchGear 3'UTR luciferase reporter plasmids for RBMS2
	SwitchGear Promoter luciferase reporter plasmids for RBMS2

Search ThermoFisher Antibodies for RBMS2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RBMS2

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RBMS2

Sirion Biotech Customized:

	stable knockdown cell line services for RBMS2
	inducible knockdown cell line services for RBMS2
	design and validation of potent shRNA sequences against RBMS2
	adenovirus for potent knockdown of RBMS2
	adenovirus for overexpression of RBMS2
	stable overexpressing cell line services for RBMS2
	inducible overexpressing cell line services for RBMS2

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RBMS2 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

RBMS2 Gene

RNA binding motif, single stranded interacting protein 2

Aliases
for RBMS2 gene

Summaries
for RBMS2 gene

Genomic Views
for RBMS2 gene

Proteins
for RBMS2 gene

Protein Domains /
Families
for RBMS2 gene

Function
for RBMS2 gene

Pathways & Interactions
for RBMS2 gene

Drugs & Compounds
for RBMS2 gene

Transcripts
for RBMS2 gene

Expression
for RBMS2 gene

Orthologs
for RBMS2 gene

Paralogs
for RBMS2 gene

Genomic Variants
for RBMS2 gene

Disorders / Diseases
for RBMS2 gene

Publications
for RBMS2 gene

External Searches for RBMS2 gene

Genome Databases showing RBMS2 gene

Other Databases showing RBMS2 gene

Specialized Databases showing RBMS2 gene

Intellectual Property
for RBMS2 gene

Products
for RBMS2 gene

View Random Gene

Advanced Search

Export list of displayed genes

RBMS2 Gene

RNA binding motif, single stranded interacting protein 2

Aliasesfor RBMS2 gene

Summariesfor RBMS2 gene

Genomic Viewsfor RBMS2 gene

Proteinsfor RBMS2 gene

Protein Domains /Familiesfor RBMS2 gene

Functionfor RBMS2 gene

Pathways & Interactionsfor RBMS2 gene

Drugs & Compoundsfor RBMS2 gene

Transcriptsfor RBMS2 gene

Expression for RBMS2 gene

Orthologsfor RBMS2 gene

Paralogsfor RBMS2 gene

Genomic Variantsfor RBMS2 gene

Disorders / Diseasesfor RBMS2 gene

Publicationsfor RBMS2 gene

External Searches for RBMS2 gene

Genome Databases showing RBMS2 gene

Other Databases showing RBMS2 gene

Specialized Databases showing RBMS2 gene

Intellectual Propertyfor RBMS2 gene

Productsfor RBMS2 gene

View Random Gene

Aliases
for RBMS2 gene

Summaries
for RBMS2 gene

Genomic Views
for RBMS2 gene

Proteins
for RBMS2 gene

Protein Domains /
Families
for RBMS2 gene

Function
for RBMS2 gene

Pathways & Interactions
for RBMS2 gene

Drugs & Compounds
for RBMS2 gene

Transcripts
for RBMS2 gene

Expression
for RBMS2 gene

Orthologs
for RBMS2 gene

Paralogs
for RBMS2 gene

Genomic Variants
for RBMS2 gene

Disorders / Diseases
for RBMS2 gene

Publications
for RBMS2 gene

Intellectual Property
for RBMS2 gene

Products
for RBMS2 gene